IL123256A0 - Methods for dna amplification and sequencing - Google Patents

Methods for dna amplification and sequencing

Info

Publication number: IL123256A0
Authority: IL; Israel
Prior art keywords: thp; dna; sequencing; methods; tetrahydropyrimidine
Prior art date: 1998-02-10

Application number

IL12325698A

Other languages

English (en)

Original Assignee

Yeda Res & Dev

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-02-10

Filing date

1998-02-10

Publication date

1998-09-24

1998-02-10 Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev

1998-02-10 Priority to IL12325698A priority Critical patent/IL123256A0/xx

1998-09-24 Publication of IL123256A0 publication Critical patent/IL123256A0/xx

1999-02-08 Priority to EP99903891A priority patent/EP1053350B1/de

1999-02-08 Priority to IL13772599A priority patent/IL137725A/en

1999-02-08 Priority to US09/601,943 priority patent/US6428986B1/en

1999-02-08 Priority to JP2000531590A priority patent/JP4393700B2/ja

1999-02-08 Priority to DE69940662T priority patent/DE69940662D1/de

1999-02-08 Priority to AT99903891T priority patent/ATE427361T1/de

1999-02-08 Priority to ES99903891T priority patent/ES2323561T3/es

1999-02-08 Priority to PCT/IL1999/000080 priority patent/WO1999041410A1/en

2002-04-08 Priority to US10/117,077 priority patent/US7150980B1/en

2006-08-31 Priority to US11/513,206 priority patent/US7387878B2/en

Links

238000000034 method Methods 0.000 title abstract 2
230000004544 DNA amplification Effects 0.000 title 1
238000012163 sequencing technique Methods 0.000 title 1
108020004414 DNA Proteins 0.000 abstract 2
102000053602 DNA Human genes 0.000 abstract 2
ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 abstract 2
238000002844 melting Methods 0.000 abstract 2
230000008018 melting Effects 0.000 abstract 2
238000003752 polymerase chain reaction Methods 0.000 abstract 2
WQXNXVUDBPYKBA-UHFFFAOYSA-N 2-Methyl-4-carboxy-3,4,5,6-tetrahydropyrimidine Chemical compound CC1=NCCC(C(O)=O)N1 WQXNXVUDBPYKBA-UHFFFAOYSA-N 0.000 abstract 1
KIIBBJKLKFTNQO-UHFFFAOYSA-N 5-hydroxy-2-methyl-1,4,5,6-tetrahydropyrimidin-3-ium-6-carboxylate Chemical compound CC1=NCC(O)C(C(O)=O)N1 KIIBBJKLKFTNQO-UHFFFAOYSA-N 0.000 abstract 1
238000001712 DNA sequencing Methods 0.000 abstract 1
230000006820 DNA synthesis Effects 0.000 abstract 1
102000016928 DNA-directed DNA polymerase Human genes 0.000 abstract 1
108010014303 DNA-directed DNA polymerase Proteins 0.000 abstract 1
ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 abstract 1
230000003321 amplification Effects 0.000 abstract 1
230000001404 mediated effect Effects 0.000 abstract 1
238000003199 nucleic acid amplification method Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Physics & Mathematics (AREA)
Biotechnology (AREA)
Analytical Chemistry (AREA)
Biophysics (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Chemical Kinetics & Catalysis (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Saccharide Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Enzymes And Modification Thereof (AREA)

IL12325698A 1998-02-10 1998-02-10 Methods for dna amplification and sequencing IL123256A0 (en)

Priority Applications (11)

Application Number	Priority Date	Filing Date	Title
IL12325698A IL123256A0 (en)	1998-02-10	1998-02-10	Methods for dna amplification and sequencing
PCT/IL1999/000080 WO1999041410A1 (en)	1998-02-10	1999-02-08	Methods for dna amplification and sequencing
JP2000531590A JP4393700B2 (ja)	1998-02-10	1999-02-08	Ｄｎａ増幅法および配列決定方法
IL13772599A IL137725A (en)	1998-02-10	1999-02-08	Method for dna amplification and sequencing
US09/601,943 US6428986B1 (en)	1998-02-10	1999-02-08	Methods for DNA amplificating and sequencing
EP99903891A EP1053350B1 (de)	1998-02-10	1999-02-08	Verfahren zur dna-amplifikation und -sequenzierung
DE69940662T DE69940662D1 (de)	1998-02-10	1999-02-08	Verfahren zur dna-amplifikation und -sequenzierung
AT99903891T ATE427361T1 (de)	1998-02-10	1999-02-08	Verfahren zur dna-amplifikation und - sequenzierung
ES99903891T ES2323561T3 (es)	1998-02-10	1999-02-08	Metodos para amplificar y secuenciar adn.
US10/117,077 US7150980B1 (en)	1998-02-10	2002-04-08	Methods for DNA amplification and sequencing
US11/513,206 US7387878B2 (en)	1998-02-10	2006-08-31	Methods for DNA amplification and sequencing

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IL12325698A IL123256A0 (en)	1998-02-10	1998-02-10	Methods for dna amplification and sequencing

Publications (1)

Publication Number	Publication Date
IL123256A0 true IL123256A0 (en)	1998-09-24

Family

ID=11071218

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL12325698A IL123256A0 (en)	1998-02-10	1998-02-10	Methods for dna amplification and sequencing

Country Status (8)

Country	Link
US (3)	US6428986B1 (de)
EP (1)	EP1053350B1 (de)
JP (1)	JP4393700B2 (de)
AT (1)	ATE427361T1 (de)
DE (1)	DE69940662D1 (de)
ES (1)	ES2323561T3 (de)
IL (1)	IL123256A0 (de)
WO (1)	WO1999041410A1 (de)

Families Citing this family (40)

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IL123256A0 (en) *	1998-02-10	1998-09-24	Yeda Res & Dev	Methods for dna amplification and sequencing
US6787305B1 (en)	1998-03-13	2004-09-07	Invitrogen Corporation	Compositions and methods for enhanced synthesis of nucleic acid molecules
US6780591B2 (en)	1998-05-01	2004-08-24	Arizona Board Of Regents	Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US7875440B2 (en)	1998-05-01	2011-01-25	Arizona Board Of Regents	Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
DK1129064T3 (da)	1998-11-12	2008-04-28	Invitrogen Corp	Transfektionsreagenser
US7501245B2 (en)	1999-06-28	2009-03-10	Helicos Biosciences Corp.	Methods and apparatuses for analyzing polynucleotide sequences
US6818395B1 (en)	1999-06-28	2004-11-16	California Institute Of Technology	Methods and apparatus for analyzing polynucleotide sequences
US7101111B2 (en) *	1999-07-19	2006-09-05	Exodyne Technologies Inc.	Flared energy absorbing system and method
US7306397B2 (en) *	2002-07-22	2007-12-11	Exodyne Technologies, Inc.	Energy attenuating safety system
WO2001023618A2 (en) *	1999-09-30	2001-04-05	Qiagen Genomics, Inc.	Compositions and methods for reducing oligonucleotide hybridization and priming specificity
CN1326990A (zh) *	2000-06-07	2001-12-19	上海博德基因开发有限公司	一种新的多肽——人类dna cgg重复结合蛋白16.17和编码这种多肽的多核苷酸
EP1368497A4 (de)	2001-03-12	2007-08-15	California Inst Of Techn	Verfahren und vorrichtung zur analyse von polynukleotidsequenzen durch asynchrone basenverlängerung
WO2004035818A1 (en) *	2002-10-21	2004-04-29	Biotage Ab	Use of osmolytes to heat stabilise luciferase and/or apyrase
US8323897B2 (en)	2002-12-04	2012-12-04	Applied Biosystems, Llc	Multiplex amplification of polynucleotides
US20060193688A1 (en) *	2003-03-05	2006-08-31	Albritton James R	Flared Energy Absorbing System and Method
EP1618187A4 (de) *	2003-04-29	2006-12-20	Ge Healthcare Bio Sciences	Amplifikation von nukleinsäuresequenzen mit mehrfachpriming
DE602004016440D1 (de) *	2003-11-06	2008-10-23	Rohm & Haas Elect Mat	Optischer Gegenstand mit leitender Struktur
US7169560B2 (en)	2003-11-12	2007-01-30	Helicos Biosciences Corporation	Short cycle methods for sequencing polynucleotides
WO2005080605A2 (en)	2004-02-19	2005-09-01	Helicos Biosciences Corporation	Methods and kits for analyzing polynucleotide sequences
CA2560513A1 (en)	2004-04-08	2005-12-01	Biomatrica, Inc.	Integration of sample storage and sample management for life science
DE602005027700D1 (de)	2004-05-25	2011-06-09	Helicos Biosciences Corp	Verfahren zur nukleinsäureimmobilisierung
US7476734B2 (en)	2005-12-06	2009-01-13	Helicos Biosciences Corporation	Nucleotide analogs
US7220549B2 (en)	2004-12-30	2007-05-22	Helicos Biosciences Corporation	Stabilizing a nucleic acid for nucleic acid sequencing
US7482120B2 (en)	2005-01-28	2009-01-27	Helicos Biosciences Corporation	Methods and compositions for improving fidelity in a nucleic acid synthesis reaction
ATE551433T1 (de)	2005-05-06	2012-04-15	Gen Probe Inc	Verfahren und produkte zum erfassen von nukleinsäurezielen
ITMI20051050A1 (it) *	2005-06-07	2006-12-08	Roberto Sapio	"metodo per la determinazione delle sequenze di acidi nucleici e analoghi"
US7666593B2 (en)	2005-08-26	2010-02-23	Helicos Biosciences Corporation	Single molecule sequencing of captured nucleic acids
US7397546B2 (en)	2006-03-08	2008-07-08	Helicos Biosciences Corporation	Systems and methods for reducing detected intensity non-uniformity in a laser beam
US8568982B2 (en) *	2006-08-09	2013-10-29	National University Of Singapore	Methods of nucleic acid synthesis using particular crowding agents and concentrations
WO2010065629A2 (en) *	2008-12-02	2010-06-10	Kapabiosystems	Nucleic acid amplification
EP2430195B1 (de) *	2009-05-11	2019-01-23	Biomatrica, INC.	Zusammensetzungen und verfahren zur lagerung biologischer proben
CA2806670A1 (en)	2010-07-26	2012-02-09	Biomatrica, Inc.	Compositions for stabilizing dna, rna and proteins in blood and other biological samples during shipping and storage at ambient temperatures
US9845489B2 (en)	2010-07-26	2017-12-19	Biomatrica, Inc.	Compositions for stabilizing DNA, RNA and proteins in saliva and other biological samples during shipping and storage at ambient temperatures
EP2683814A4 (de)	2011-03-11	2014-09-24	Univ Singapore	Perizytenvorläufer aus peripherem blut
US9725703B2 (en)	2012-12-20	2017-08-08	Biomatrica, Inc.	Formulations and methods for stabilizing PCR reagents
EP2935664A4 (de) *	2012-12-21	2016-08-17	Ibis Biosciences Inc	Stabilisierte nanoporen- und mikroporenstrukturen sowie verfahren zur herstellung und verwendung davon
CN106572650B (zh)	2014-06-10	2021-08-31	生物马特里卡公司	在环境温度下稳定凝血细胞
WO2016011203A1 (en)	2014-07-15	2016-01-21	Life Technologies Corporation	Compositions with lipid aggregates and methods for efficient delivery of molecules to cells
SG11201804776SA (en)	2015-12-08	2018-07-30	Biomatrica Inc	Reduction of erythrocyte sedimentation rate
KR102441122B1 (ko) *	2020-05-11	2022-09-07	주식회사 엔지노믹스	폴리머라제 활성 측정 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL100810A (en) *	1992-01-30	1996-12-05	Yeda Res & Dev	Pharmaceutical preparations including 2 - methyl - carboxy - 5 - hydroxy - tetrahydropyrimidine and / or 2 - methyl - 4 - carboxy - tetrahydropyrimidine, plywood methods
US5432065A (en)	1993-03-30	1995-07-11	United States Biochemical Corporation	Cycle sequencing with non-thermostable DNA polymerases
DE69531487T2 (de) *	1994-01-31	2004-06-17	The Regents Of The University Of California, Oakland	Methode zur eliminierung von sequenzierartefakten
US5545539A (en) *	1994-10-18	1996-08-13	Genzyme Corporation	Method for nucleotide sequence amplification
FR2733515B1 (fr) *	1995-04-27	1997-09-05	Cis Bio Int	Tampon, procede et methode d'evaluation des conditions optimales, d'amplification de sequences cibles d'acide nucleique, et leurs applications
GB9524974D0 (en) *	1995-12-06	1996-02-07	Amersham Int Plc	An improved method for dye-terminator (cycle) sequencing
AU8162598A (en)	1997-06-25	1999-01-04	Life Technologies, Inc.	Improved method for isolating and recovering target dna or rna molecules having a desired nucleotide sequence
IL123256A0 (en) *	1998-02-10	1998-09-24	Yeda Res & Dev	Methods for dna amplification and sequencing

1998
- 1998-02-10 IL IL12325698A patent/IL123256A0/xx unknown
1999
- 1999-02-08 WO PCT/IL1999/000080 patent/WO1999041410A1/en not_active Ceased
- 1999-02-08 JP JP2000531590A patent/JP4393700B2/ja not_active Expired - Lifetime
- 1999-02-08 DE DE69940662T patent/DE69940662D1/de not_active Expired - Lifetime
- 1999-02-08 ES ES99903891T patent/ES2323561T3/es not_active Expired - Lifetime
- 1999-02-08 EP EP99903891A patent/EP1053350B1/de not_active Expired - Lifetime
- 1999-02-08 AT AT99903891T patent/ATE427361T1/de not_active IP Right Cessation
- 1999-02-08 US US09/601,943 patent/US6428986B1/en not_active Expired - Lifetime
2002
- 2002-04-08 US US10/117,077 patent/US7150980B1/en not_active Expired - Lifetime
2006
- 2006-08-31 US US11/513,206 patent/US7387878B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP1053350A1 (de)	2000-11-22
ES2323561T3 (es)	2009-07-20
WO1999041410A1 (en)	1999-08-19
US7150980B1 (en)	2006-12-19
US7387878B2 (en)	2008-06-17
JP2002503482A (ja)	2002-02-05
JP4393700B2 (ja)	2010-01-06
DE69940662D1 (de)	2009-05-14
US6428986B1 (en)	2002-08-06
ATE427361T1 (de)	2009-04-15
US20070212760A1 (en)	2007-09-13
EP1053350B1 (de)	2009-04-01

Publication	Publication Date	Title
IL123256A0 (en)	1998-09-24	Methods for dna amplification and sequencing
EP2272952B8 (de)	2012-08-15	Thermostabiler oder thermoactiver DNA-polymerase mit abgeschwächter 3'-5' Exonukleaseaktivität
DK0669401T3 (da)	2002-04-02	Amplificering af lange nukleinsyresekvenser ved PCR
PT833944E (pt)	2009-04-14	Ligandos de ácido nucleico que se ligam a, e inibem, adn-polimerases
DK1040202T3 (da)	2009-04-14	DNA-polymorfiidentitetsbestemmelse under anvendelse af flowcytometri
DE60112746D1 (de)	2005-09-22	Kälteempfindliche dna-polymerasemutanten
DE69923180D1 (de)	2005-02-17	Thermostabiles Enzym welches die Genauigkeit thermostabiler DNA Polymerasen erhöht - zur Verbesserung der Nucleinsäuresynthese und in vitro Amplifikation
DK0550696T3 (da)	2001-03-19	Oprenset termostabilt nukleinsyre-polymeraseenzym fra Thermosipho africanus
EP1050587A3 (de)	2004-02-04	Erzeugung und Amplifizierung von Nukleinsäuren ausgehend von Ribonukleinsäuren
EP0975806A4 (de)	2004-10-06	Zusammensetzungen und verfahren der reversen transkriptase-polymerasekettenreaktion (rt-pcr)
CA2052413A1 (en)	1992-03-29	Nucleotides sequences useful as type-specific probes, pcr primers and lcr probes for the amplifications and detection of human papilloma virus, and related kits and methods
WO2003027258A3 (en)	2003-11-13	RECOMBINANT DNA PROCESSES USING A dNTP MIXTURE CONTAINING MODIFIED NUCLEOTIDES
ATE330031T1 (de)	2006-07-15	Reversibel inhibierende sonden
AU2002305073A1 (en)	2002-10-08	Synthesis of selenium-derivatized nucleosides, nucleotides, phosphoramidites, triphosphates and nucleic acids
EP2314596A3 (de)	2011-07-06	DNA-Polymerase-mischungen und mutante DNA-polymerasen
NO991566D0 (no)	1999-03-30	Termostabil nukleinsyre og polymerase fra Thermococcus gorgonarius
AU2003257177A8 (en)	2004-02-23	Improved compositions for in vitro amplification of nucleic acids
WO2000068422A3 (en)	2002-04-04	High density labeling of dna with modified or 'chromophore' carrying nucleotides and dna polymerases used
WO2004067775A3 (en)	2004-12-09	Method for the detection of cytosine methylation patterns with high sensitivity
Steinman	1993	Improvement of primer directed nucleic acid amplification including the addition of specific template DNA inactivating enzyme
KR950023714A (ko)	1995-08-18	중합 효소 연쇄 반응 조성물