IL123915A - Lipid alcohols as immunosuppressive and antiviral drugs - Google Patents

Lipid alcohols as immunosuppressive and antiviral drugs

Info

Publication number: IL123915A
Authority: IL; Israel
Prior art keywords: oxicarbonyl; carbonylamido; amidocarbonyl; alkylmercapto; carbonyloxy
Prior art date: 1995-10-14

Application number

IL12391596A

Other languages

English (en)

Original Assignee

Heidelberg Pharma Holding Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-10-14

Filing date

1996-10-11

Publication date

2003-01-12

1996-10-11 Application filed by Heidelberg Pharma Holding Gmbh filed Critical Heidelberg Pharma Holding Gmbh

2003-01-12 Publication of IL123915A publication Critical patent/IL123915A/xx

Links

-1 Lipid alcohols Chemical class 0.000 title abstract 2
230000001506 immunosuppresive effect Effects 0.000 title abstract 2
239000003443 antiviral agent Substances 0.000 title 1
239000003018 immunosuppressive agent Substances 0.000 title 1
125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 2
125000004454 (C1-C6) alkoxycarbonyl group Chemical group 0.000 abstract 2
125000004739 (C1-C6) alkylsulfonyl group Chemical group 0.000 abstract 2
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
239000005864 Sulphur Substances 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
125000004414 alkyl thio group Chemical group 0.000 abstract 2
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 2
125000005708 carbonyloxy group Chemical group [*:2]OC([*:1])=O 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
229910052760 oxygen Inorganic materials 0.000 abstract 2
239000001301 oxygen Substances 0.000 abstract 2
229920006395 saturated elastomer Polymers 0.000 abstract 2
125000000475 sulfinyl group Chemical group [*:2]S([*:1])=O 0.000 abstract 2
125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 abstract 2
125000004738 (C1-C6) alkyl sulfinyl group Chemical group 0.000 abstract 1
239000013543 active substance Substances 0.000 abstract 1
230000000840 anti-viral effect Effects 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
239000008177 pharmaceutical agent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/08—Ethers or acetals acyclic, e.g. paraformaldehyde
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/10—Sulfides; Sulfoxides; Sulfones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C317/18—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
AIDS & HIV (AREA)
Molecular Biology (AREA)
Transplantation (AREA)
Tropical Medicine & Parasitology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

IL12391596A 1995-10-14 1996-10-11 Lipid alcohols as immunosuppressive and antiviral drugs IL123915A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19538402A DE19538402A1 (de)	1995-10-14	1995-10-14	Lipidalkohole als neue immunsuppressive und antivirale Arzneimittel
PCT/EP1996/004438 WO1997014410A1 (fr)	1995-10-14	1996-10-11	Alcools lipidiques comme nouveaux medicaments immunosuppresseurs et antiviraux

Publications (1)

Publication Number	Publication Date
IL123915A true IL123915A (en)	2003-01-12

Family

ID=7774931

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL12391596A IL123915A (en)	1995-10-14	1996-10-11	Lipid alcohols as immunosuppressive and antiviral drugs

Country Status (18)

Country	Link
US (1)	US6177469B1 (fr)
EP (1)	EP0854708B1 (fr)
JP (1)	JPH11513677A (fr)
KR (1)	KR19990064240A (fr)
AT (1)	ATE210434T1 (fr)
AU (1)	AU722835B2 (fr)
CA (1)	CA2234244A1 (fr)
DE (2)	DE19538402A1 (fr)
DK (1)	DK0854708T3 (fr)
ES (1)	ES2169816T3 (fr)
HU (1)	HUP9900725A3 (fr)
IL (1)	IL123915A (fr)
NO (1)	NO981629L (fr)
NZ (1)	NZ320211A (fr)
PT (1)	PT854708E (fr)
TW (1)	TW426513B (fr)
WO (1)	WO1997014410A1 (fr)
ZA (1)	ZA968597B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1293795B1 (it) *	1997-07-28	1999-03-10	Angelini Ricerche Spa	Farmaco attivo nel ridurre la produzione di proteina mcp-1
US6406722B1 (en)	1999-02-18	2002-06-18	Robert G. Gallaher	Method of treating viral infections and lesions with taxane compounds
CA2424345A1 (fr) *	2000-10-16	2002-04-25	Neopharm, Inc.	Preparation liposomales a base de mitoxantrone
WO2006115509A2 (fr)	2004-06-24	2006-11-02	Novartis Vaccines And Diagnostics Inc.	Immuno-potentialisateurs a petites molecules et analyses visant a detecter leur presence
US7341985B2 (en) *	2004-10-08	2008-03-11	Air Products And Chemicals, Inc.	2-Hydroxy-3-alkoxypropyl sulfides, sulfones, and sulfoxides: new surface active agents
WO2009129395A1 (fr) *	2008-04-16	2009-10-22	Abbott Laboratories	Lipides cationiques et utilisations de ceux-ci

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4857511A (en) *	1985-09-17	1989-08-15	Burroughs Wellcome Co.	Treatment of human viral infections
DE3638126A1 (de) *	1986-11-08	1988-05-11	Nattermann A & Cie	Mercaptoalkanolphospholipide und deren derivate, verfahren zu ihrer herstellung und ihre verwendung als wirkstoffe in arzneimitteln
US4997851A (en) *	1987-12-31	1991-03-05	Isaacs Charles E	Antiviral and antibacterial activity of fatty acids and monoglycerides
DE3929217A1 (de) *	1989-09-02	1991-03-07	Boehringer Mannheim Gmbh	Verwendung von phospholipid-derivaten als antivirale arzneimittel und neue phospholipide
DE3934820A1 (de) *	1989-10-19	1991-04-25	Boehringer Mannheim Gmbh	Verwendung von lecithin-analoga als antivirale arzneimittel und neue derivate

1995
- 1995-10-14 DE DE19538402A patent/DE19538402A1/de not_active Withdrawn
1996
- 1996-10-11 PT PT96934651T patent/PT854708E/pt unknown
- 1996-10-11 US US09/051,088 patent/US6177469B1/en not_active Expired - Fee Related
- 1996-10-11 EP EP96934651A patent/EP0854708B1/fr not_active Expired - Lifetime
- 1996-10-11 DE DE59608464T patent/DE59608464D1/de not_active Expired - Fee Related
- 1996-10-11 HU HU9900725A patent/HUP9900725A3/hu unknown
- 1996-10-11 ZA ZA9608597A patent/ZA968597B/xx unknown
- 1996-10-11 WO PCT/EP1996/004438 patent/WO1997014410A1/fr not_active Ceased
- 1996-10-11 DK DK96934651T patent/DK0854708T3/da active
- 1996-10-11 NZ NZ320211A patent/NZ320211A/xx unknown
- 1996-10-11 IL IL12391596A patent/IL123915A/xx not_active IP Right Cessation
- 1996-10-11 AT AT96934651T patent/ATE210434T1/de not_active IP Right Cessation
- 1996-10-11 KR KR1019980702727A patent/KR19990064240A/ko not_active Ceased
- 1996-10-11 AU AU72912/96A patent/AU722835B2/en not_active Ceased
- 1996-10-11 JP JP9515499A patent/JPH11513677A/ja not_active Ceased
- 1996-10-11 ES ES96934651T patent/ES2169816T3/es not_active Expired - Lifetime
- 1996-10-11 CA CA002234244A patent/CA2234244A1/fr not_active Abandoned
- 1996-10-14 TW TW085112614A patent/TW426513B/zh not_active IP Right Cessation
1998
- 1998-04-08 NO NO981629A patent/NO981629L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
AU722835B2 (en)	2000-08-10
DK0854708T3 (da)	2002-04-08
CA2234244A1 (fr)	1997-04-24
DE19538402A1 (de)	1997-04-17
AU7291296A (en)	1997-05-07
HUP9900725A2 (hu)	1999-06-28
ATE210434T1 (de)	2001-12-15
EP0854708A1 (fr)	1998-07-29
NO981629L (no)	1998-06-12
ES2169816T3 (es)	2002-07-16
ZA968597B (en)	1998-04-14
PT854708E (pt)	2002-06-28
JPH11513677A (ja)	1999-11-24
TW426513B (en)	2001-03-21
KR19990064240A (ko)	1999-07-26
WO1997014410A1 (fr)	1997-04-24
DE59608464D1 (de)	2002-01-24
US6177469B1 (en)	2001-01-23
NZ320211A (en)	2000-01-28
HUP9900725A3 (en)	2001-08-28
EP0854708B1 (fr)	2001-12-12
NO981629D0 (no)	1998-04-08

Legal Events

Date	Code	Title
2003-07-31	FF	Patent granted
2003-07-31	KB	Patent renewed
2007-07-24	MM9K	Patent not in force due to non-payment of renewal fees

Publication	Publication Date	Title
AU2822889A (en)	1989-07-05	Macrocyclic compounds
ES2098672T3 (es)	1997-05-01	Composiciones farmaceuticas estabilizadas que contienen derivados de vitaminas d2 y d3.
FI893359A0 (fi)	1989-07-11	Fr 901228-foerening och foerfarande foer dess framstaellning.
BR9815778A (pt)	2001-10-30	Composição nanocompósita de polìmero
ES2192273T3 (es)	2003-10-01	Procedimiento para producir compuestos de ecteinascidina.
EP1273299A4 (fr)	2003-05-14	Preparations a base de minoxidil
DE60000031D1 (de)	2001-12-20	Kosmetische Zusammensetzung enthaltend die Kombination von einem besonderen Ester und einer Silikonverbindung
DE60224180D1 (de)	2008-01-31	Cycloalkancarbonsäurederivate als duftstoffe mit moschuscharakter
NZ330078A (en)	2000-01-28	Active oxygen carriers containing pterin derivatives and salts thereof for use as cosmetic agents and feed
IL123915A (en)	2003-01-12	Lipid alcohols as immunosuppressive and antiviral drugs
IT1248061B (it)	1995-01-05	Policarbonati e loro uso per la preparazione di matrici bioerodibili
BR9912706A (pt)	2002-01-29	Composições farmacêuticas contendo ibuprofeno e domperidona
AU1843497A (en)	1997-08-22	Dihydrobenzofuran compounds useful as anti-inflammatory agents
BR9816072A (pt)	2001-08-14	Composição clareadora da pele contendo um composto de ácido ascórbico
IT1147330B (it)	1986-11-19	Medicamento,o preparato farmaceutico,ad azione citostatica
MXPA04005308A (es)	2004-09-13	Compuestos organicos.
AR004896A1 (es)	1999-04-07	Derivados de pirazoles acidos, procedimiento de preparación, medicamentos y las composiciones farmacueitcas que los contienen, compuestos para suexclusivo uso en dicho procedimiento y utilizacion de dichos derivados para preparar composiciones farmaceuticas.
ES2102774T3 (es)	1997-08-01	Indolsulfonamidas como agentes antitumorales.
DE60115687D1 (de)	2006-01-12	Stabilisierte arzneizusammensetzungen von oxapenem-3-carbonsäuren durch gefriertrocknen mit pharmazeutischen trägermitteln
AR003452A1 (es)	1998-08-05	Dimaleato de n,n-dietil-8,8-dipropil-2-azaspiro [4.5]decano-2-propanamina y una composicion farmaceutica que lo comprende.
ES2063766T3 (es)	1995-01-16	Esteres biaromaticos de antibioticos macrolidicos y lincosamidicos, su procedimiento de preparacion y composiciones farmaceuticas y cosmeticas que los contienen.
SE8803143L (sv)	1990-03-08	Alternativa energisubstrat
CA2238710A1 (fr)	1997-06-05	Nouveaux derives d'aminoalcools, leur procede de production et medicaments contenant ces composes