IL124236A - Pharmaceutical composition for treating or reversing diabetic cardiomyopathy comprising aldose reductase inhibitor - Google Patents

Pharmaceutical composition for treating or reversing diabetic cardiomyopathy comprising aldose reductase inhibitor

Info

Publication number
IL124236A
IL124236A IL12423698A IL12423698A IL124236A IL 124236 A IL124236 A IL 124236A IL 12423698 A IL12423698 A IL 12423698A IL 12423698 A IL12423698 A IL 12423698A IL 124236 A IL124236 A IL 124236A
Authority
IL
Israel
Prior art keywords
treating
pharmaceutical composition
aldose reductase
reductase inhibitor
diabetic cardiomyopathy
Prior art date
Application number
IL12423698A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL124236A publication Critical patent/IL124236A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/502—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
IL12423698A 1997-05-05 1998-04-27 Pharmaceutical composition for treating or reversing diabetic cardiomyopathy comprising aldose reductase inhibitor IL124236A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4582297P 1997-05-05 1997-05-05

Publications (1)

Publication Number Publication Date
IL124236A true IL124236A (en) 2003-01-12

Family

ID=21940071

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12423698A IL124236A (en) 1997-05-05 1998-04-27 Pharmaceutical composition for treating or reversing diabetic cardiomyopathy comprising aldose reductase inhibitor

Country Status (17)

Country Link
US (1) US5990111A (de)
EP (1) EP0880964B1 (de)
JP (1) JP3010153B2 (de)
KR (1) KR19980086748A (de)
AT (1) ATE277607T1 (de)
AU (1) AU725621B2 (de)
CA (1) CA2236553C (de)
DE (1) DE69826561T2 (de)
DK (1) DK0880964T3 (de)
ES (1) ES2227773T3 (de)
HU (1) HUP9801022A3 (de)
IL (1) IL124236A (de)
MY (1) MY136261A (de)
NZ (1) NZ330359A (de)
PT (1) PT880964E (de)
TW (1) TW589184B (de)
ZA (1) ZA983720B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6555540B1 (en) * 1999-06-30 2003-04-29 Pfizer Inc Combinations of aldose reductase inhibitors and selective cyclooxygenase-2 inhibitors
US6426341B1 (en) * 1999-06-30 2002-07-30 Pfizer Inc. Treatment for diabetic complications
US6413965B1 (en) * 1999-06-30 2002-07-02 Pfizer Inc. Compositions and treatment for diabetic complications
AU7063300A (en) * 1999-08-23 2001-03-19 University Of Virginia Patent Foundation Method and apparatus for predicting the risk of hypoglycemia
US6380200B1 (en) * 1999-12-07 2002-04-30 Pfizer, Inc. Combination of aldose reductase inhibitors and selective serotonin reuptake inhibitors for the treatment of diabetic complications
EP1106210A3 (de) * 1999-12-07 2003-12-03 Pfizer Products Inc. Zusammensetzungen, für die Behandlung von diabetischen Komplikationen, welche Aldosereductasehemmern und antihypertensive Mitteln enthalten
CO5271699A1 (es) 2000-01-24 2003-04-30 Pfizer Prod Inc Procedimiento para el tratamiento de cardiomiopatia utilizando inhibidores de la glucogeno fosforilasa
WO2002079506A1 (en) * 2001-03-30 2002-10-10 The Chinese University Of Hong Kong Determination of risk factors for cataract by aldose reductase genotype
WO2003105864A1 (en) * 2002-06-13 2003-12-24 Board Of Regents, The University Of Texas System Methods and compositions involving aldose reductase inhibitors
US20110092566A1 (en) * 2004-11-19 2011-04-21 Srivastava Satish K Treatment of cancer with aldose reductase inhibitors
EP2848252A3 (de) 2007-03-23 2015-06-17 The Board of Regents of the University of Texas System Aldose-Reduktase-Inhibitoren zur Behandlung von Uveitis
US20090270490A1 (en) * 2008-04-24 2009-10-29 The Board Of Regents Of The University Of Texas System Methods involving aldose reductase inhibition
WO2012088525A2 (en) 2010-12-23 2012-06-28 The Board Of Regents Of The University Of Texas System Methods for treating copd

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3684410D1 (de) * 1985-11-07 1992-04-23 Pfizer Heterocyclische oxophthalazinylessigsaeure.
US4748280A (en) * 1985-11-07 1988-05-31 Pfizer Inc. Certain chlorination process for preparing 2-chloro-1,1,1-(C1 -C6)
US4939140A (en) * 1985-11-07 1990-07-03 Pfizer Inc. Heterocyclic oxophthalazinyl acetic acids
US4743611A (en) * 1986-07-02 1988-05-10 American Home Products Corp. Naphthalenylsulfonylimidazolidinediones and their thioxo analogs useful as aldose reductase inhibitors
JPH0676391B2 (ja) * 1987-06-09 1994-09-28 フアイザー・インコーポレイテツド ベンゾチアゾール等の複素環側鎖を有するオキソフタラジニル酢酸類の製造方法
US4868301A (en) * 1987-06-09 1989-09-19 Pfizer Inc. Processes and intermediates for the preparation of oxophthalazinyl acetic acids having benzothiazole or other heterocyclic side chains
EP0322153A3 (de) * 1987-12-21 1990-08-16 Pfizer Inc. Heterozyklyl Oxophtalazynyl-Essigsäuren
US4954629A (en) * 1989-05-11 1990-09-04 Pfizer Inc. Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof
US5164391A (en) * 1989-09-20 1992-11-17 Sanwa Kagaku Kenkyusho Co., Ltd. Hydantoin derivatives for treating complications of diabetes and circulatory diseases
FI922308A7 (fi) * 1989-12-15 1992-05-21 Pfizer Substituoituja oksoftalatsinyylietikkahappoja ja niiden anologeja
US5064830A (en) * 1990-08-02 1991-11-12 Pfizer Inc. Lowering of blood uric acid levels
US5728704A (en) * 1992-09-28 1998-03-17 Pfizer Inc. Substituted pyridmidines for control of diabetic complications
US5391551A (en) * 1993-05-10 1995-02-21 Pfizer Inc. Method of lowering blood lipid levels
US5834466A (en) * 1994-12-22 1998-11-10 The Regents Of The University Of California Method for protecting of heart by limiting metabolic and ionic abnormalities developed during ischemia, following ischemia or resulting from ischemia

Also Published As

Publication number Publication date
DE69826561T2 (de) 2006-03-09
EP0880964A3 (de) 2002-07-17
ES2227773T3 (es) 2005-04-01
KR19980086748A (ko) 1998-12-05
US5990111A (en) 1999-11-23
DK0880964T3 (da) 2004-12-27
EP0880964A2 (de) 1998-12-02
HUP9801022A3 (en) 2001-10-29
CA2236553A1 (en) 1998-11-05
TW589184B (en) 2004-06-01
ATE277607T1 (de) 2004-10-15
ZA983720B (en) 1999-11-04
JPH10316588A (ja) 1998-12-02
JP3010153B2 (ja) 2000-02-14
NZ330359A (en) 2000-06-23
DE69826561D1 (de) 2004-11-04
PT880964E (pt) 2004-12-31
AU725621B2 (en) 2000-10-19
HUP9801022A2 (hu) 2000-03-28
EP0880964B1 (de) 2004-09-29
AU6380198A (en) 1998-11-05
MY136261A (en) 2008-09-30
CA2236553C (en) 2002-10-29

Similar Documents

Publication Publication Date Title
NZ517616A (en) Use of retigabin for treating neuropathic pain
WO2003053383A3 (fr) Utilisation cosmetique d’au moins une hydrophobine pour le traitement des matieres keratiniques
PT1479385E (pt) Utilização de inibidores de ciclo-oxigenase 2 no tratamento e na prevenção de neoplasias
EE04356B1 (et) aP2 inhibiitor kasutamiseks suhkurtõve ravis ja seda sisaldav ravimkoostis
ATE321048T1 (de) Beta-amino-tetrahydroimidazo(1,2-a)pyrazine und - tetrahydrotriazolo(4,3-a)pyrazine als dipeptidyl peptidase inhibitoren zur behandlung oder prevention von diabetes
IL124236A (en) Pharmaceutical composition for treating or reversing diabetic cardiomyopathy comprising aldose reductase inhibitor
TR199802441A3 (tr) Kanda asiri ürik asit bulunmasinin tedavisi ve önlenmesi için yöntem ve terkip.
EP0909561A3 (de) Verwendung der Reboxetin zur Behandlung der Aufmerksamkeitsmangel/Hyperaktivität Störung
EP0930067A3 (de) Mmp inhibitoren zur behandlung von okularer angiogenesis
EE200300213A (et) SARP-1 kasutamine sklerodermia raviks ja/või ennetamiseks
AU8851298A (en) L-threonate ferrous, as well as pharmaceutical composition and use for improvingand treating human anemia thereof
EP1251847A4 (de) Neue verwendung von prodigiosin zur behandlung von diabetes mellitus
IL139144A0 (en) Mycobacterial inhibitors
IL130500A0 (en) Use of comt inhibitors for the manufacture of a medicament for the prevention of diabetic vascular dysfunctions
AU2002257598A1 (en) Agent for treating diabetes mellitus
IL126651A0 (en) Acyl urea compounds for the treatment of coccidioidomycosis in warm-blooded animals
PT1042288E (pt) Inibidores de tripeptidil peptidase
ZA200209835B (en) Combined therapy against tumors comprising substituted acryloyl distamycin derivatives, taxanes and/or anti-metabolites.
MY140504A (en) Statin-mmp inhibitor combinations
AU5434899A (en) Cancer treatment
EP1469867A4 (de) Verfahren zur behandlung von halitose
ZA982808B (en) Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of dementia
WO2003004631A3 (en) USE OF INHIBITORS OF EXPRESSION OR ACTIVITY OF p8/com1 FOR TREATING TUMORS.
ID21653A (id) Komposisi untuk pengobatan atau pencegahan pankreatitis yang mengandung turunan diarilalkana sebagai bahan aktif
NZ523676A (en) Use of cetyl myristate and cetyl palmitate to treat irritable bowel syndrome or irritable bowel disease

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees