IL124841A - Pharmaceutical compositions comprising liposomal prostaglandin a method of preparing such compositions and the use of liposomal prostaglandin for said preparation - Google Patents

Pharmaceutical compositions comprising liposomal prostaglandin a method of preparing such compositions and the use of liposomal prostaglandin for said preparation

Info

Publication number
IL124841A
IL124841A IL12484196A IL12484196A IL124841A IL 124841 A IL124841 A IL 124841A IL 12484196 A IL12484196 A IL 12484196A IL 12484196 A IL12484196 A IL 12484196A IL 124841 A IL124841 A IL 124841A
Authority
IL
Israel
Prior art keywords
compositions
liposomal prostaglandin
liposomal
prostaglandin
preparing
Prior art date
Application number
IL12484196A
Other languages
English (en)
Other versions
IL124841A0 (en
Original Assignee
Harvard Scient Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard Scient Corp filed Critical Harvard Scient Corp
Publication of IL124841A0 publication Critical patent/IL124841A0/xx
Publication of IL124841A publication Critical patent/IL124841A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gynecology & Obstetrics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL12484196A 1995-12-15 1996-11-26 Pharmaceutical compositions comprising liposomal prostaglandin a method of preparing such compositions and the use of liposomal prostaglandin for said preparation IL124841A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/573,408 US5718917A (en) 1995-12-15 1995-12-15 PGE-1 containing lyophilized liposomes for use in the treatment of erectile dysfunction
PCT/US1996/018820 WO1997022334A1 (en) 1995-12-15 1996-11-26 Pge-1 containing lyophilized liposomes for use in the treatment of erectile dysfunction

Publications (2)

Publication Number Publication Date
IL124841A0 IL124841A0 (en) 1999-01-26
IL124841A true IL124841A (en) 2001-01-28

Family

ID=24291879

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12484196A IL124841A (en) 1995-12-15 1996-11-26 Pharmaceutical compositions comprising liposomal prostaglandin a method of preparing such compositions and the use of liposomal prostaglandin for said preparation

Country Status (17)

Country Link
US (1) US5718917A (is)
EP (1) EP0874622A4 (is)
JP (1) JPH11504945A (is)
KR (1) KR20000064392A (is)
CN (1) CN1207671A (is)
AU (1) AU722555B2 (is)
BR (1) BR9612040A (is)
EA (1) EA199800565A1 (is)
EE (1) EE9800182A (is)
HU (1) HUP9902094A2 (is)
IL (1) IL124841A (is)
IS (1) IS4767A (is)
NO (1) NO982727L (is)
PL (1) PL327400A1 (is)
SK (1) SK80998A3 (is)
TR (1) TR199801104T2 (is)
WO (1) WO1997022334A1 (is)

Families Citing this family (16)

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US20050065161A1 (en) * 1996-02-02 2005-03-24 Nitromed, Inc. Nitrosated and nitrosylated alpha-adrenergic receptor antagonist compounds, compositions and their uses
KR100195348B1 (ko) * 1996-10-31 1999-06-15 장용택 안정한 프로스타글란딘 e1-함유 주사제 조성물
US6103765A (en) 1997-07-09 2000-08-15 Androsolutions, Inc. Methods for treating male erectile dysfunction
WO1999002147A1 (en) 1997-07-09 1999-01-21 Androsolutions, Inc. Improved methods and compositions for treating male erectile dysfunction
US20020004529A1 (en) * 1997-10-20 2002-01-10 Gary W. Neal Methods, compositions, and kits for enhancing female sexual desire and responsiveness
US6472425B1 (en) 1997-10-31 2002-10-29 Nitromed, Inc. Methods for treating female sexual dysfunctions
US6046240A (en) * 1998-05-01 2000-04-04 Harvard Scientific Corporation Methods for treating female sexual dysfunction
KR100350179B1 (ko) * 1998-09-23 2002-08-27 구주제약주식회사 Ｓｅｄｄｓ로 제제화한 발기부전치료용 주입액제
AU3713600A (en) * 1999-03-01 2000-09-21 Nitromed, Inc. Nitrosated and nitrosylated prostaglandins, compositions and metods of use
CN1314444C (zh) * 2003-03-20 2007-05-09 蔡海德 一种治疗糠尿病及其并发症和病毒性肝炎的组合药物及其制备方法
US20060222694A1 (en) * 2003-06-27 2006-10-05 Oh Choon K Stabilized topotecan liposomal composition and methods
US9005183B2 (en) * 2007-05-16 2015-04-14 Health Knight, Llc System and method for treating erectile dysfunction
CN101095944B (zh) * 2007-07-10 2012-04-18 上海市肿瘤研究所 一种预防和治疗前列腺炎穴位缓释贴片及其制品、制备方法和用途
CN101912363A (zh) * 2010-07-29 2010-12-15 蔡海德 溶解超滤-喷雾干燥-分子分散包衣-水化制粒-冷冻干燥生产脂质体组合药物
CN102133182A (zh) * 2010-12-30 2011-07-27 北京中海康医药科技发展有限公司 一种依前列醇脂质体及其制备方法
US9962393B1 (en) * 2015-06-21 2018-05-08 Angiosoma Research, Inc. Method for treating vascular disease by administering a liposomal prostaglandin composition

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US246697A (en) * 1881-09-06 wadleigh
US251355A (en) * 1881-12-27 Edwin h
US3993754A (en) * 1974-10-09 1976-11-23 The United States Of America As Represented By The United States Energy Research And Development Administration Liposome-encapsulated actinomycin for cancer chemotherapy
GB1536215A (en) * 1976-07-05 1978-12-20 Decca Ltd Clamping circuits for television signals
US4086257A (en) * 1976-10-12 1978-04-25 Sears Barry D Phosphatidyl quaternary ammonium compounds
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4533254A (en) * 1981-04-17 1985-08-06 Biotechnology Development Corporation Apparatus for forming emulsions
IL63734A (en) * 1981-09-04 1985-07-31 Yeda Res & Dev Lipid fraction,its preparation and pharmaceutical compositions containing same
US4677099A (en) * 1981-09-04 1987-06-30 Yeda Research And Development Co., Ltd. Medical processes employing a novel lipid fraction
US4522803A (en) * 1983-02-04 1985-06-11 The Liposome Company, Inc. Stable plurilamellar vesicles, their preparation and use
JPS58222014A (ja) * 1982-06-18 1983-12-23 Taisho Pharmaceut Co Ltd プロスタグランジンｅ↓１脂肪乳剤
US5040453A (en) * 1982-07-12 1991-08-20 Turn Act Inc. Actuator housing continuation
US4588578A (en) * 1983-08-08 1986-05-13 The Liposome Company, Inc. Lipid vesicles prepared in a monophase
US4478822A (en) * 1983-05-16 1984-10-23 Merck & Co., Inc. Drug delivery system utilizing thermosetting gels
US4610868A (en) * 1984-03-20 1986-09-09 The Liposome Company, Inc. Lipid matrix carriers for use in drug delivery systems
US5008050A (en) * 1984-06-20 1991-04-16 The Liposome Company, Inc. Extrusion technique for producing unilamellar vesicles
US4975282A (en) * 1985-06-26 1990-12-04 The Liposome Company, Inc. Multilamellar liposomes having improved trapping efficiencies
US4820732A (en) * 1985-10-04 1989-04-11 The Upjohn Company Method and compositions for reducing dysfunction in angioplasty procedures
US4955878A (en) * 1986-04-04 1990-09-11 Biotechnology, Inc. Kit for preventing or treating arterial dysfunction resulting from angioplasty procedures
US4749585A (en) * 1986-04-11 1988-06-07 University Of Medicine And Dentistry Of New Jersey Antibiotic bonded prosthesis and process for producing same
US4776991A (en) * 1986-08-29 1988-10-11 The United States Of America As Represented By The Secretary Of The Navy Scaled-up production of liposome-encapsulated hemoglobin
US4801587A (en) * 1987-03-02 1989-01-31 Gene Voss Impotence ointment
WO1988009170A1 (en) * 1987-05-22 1988-12-01 The Liposome Company, Inc. Prostaglandin-lipid formulations
US4776848A (en) * 1987-07-20 1988-10-11 Anthony Solazzo Urethral fluid application device and system
US5256652A (en) * 1987-11-12 1993-10-26 Pharmedic Co. Topical compositions and methods for treatment of male impotence
SE463851B (sv) * 1988-09-02 1991-02-04 Amsu Ltd Komposition foer behandling av erektil dysfunktion via uretra
US4880835A (en) * 1988-11-03 1989-11-14 Formulations Development Labs, Inc. Oral liquid pharmaceutical compositions of sulindac
JPH0395118A (ja) * 1989-09-07 1991-04-19 Green Cross Corp:The プロスタグランジン含有脂肪小体製剤
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IT1252603B (it) * 1990-04-19 1995-06-19 Giorgio Cavallini 2,4-diamino-6 piperidino pirimidina-3 ossido topico sul glande nel trattamento delle impotenze erettili
US5242391A (en) * 1990-04-25 1993-09-07 Alza Corporation Urethral insert for treatment of erectile dysfunction
ES2124225T3 (es) * 1990-04-25 1999-02-01 Vivus Inc Tratamiento de la disfuncion erectil.
EP0484581B1 (de) * 1990-11-08 1994-06-15 Roche Diagnostics GmbH Verwendung von Thromboxan-A2-Antagonisten zur Verhinderung von degenerativen Vorgängen im penilen Gewebe
US5399581A (en) * 1990-12-26 1995-03-21 Laragh; John H. Method and compositions for treatment of sexual impotence
ATE176401T1 (de) * 1991-05-07 1999-02-15 Liposome Co Inc Liposomale prostaglandinformulierungen
JPH05139977A (ja) * 1991-05-17 1993-06-08 Green Cross Corp:The プロスタグランジン類リポソーム複合体を充填した注射器
DE4117249C2 (de) * 1991-05-27 1998-05-14 Christian Dr Stief Linsidomin zur Behandlung erektiler Dysfunktionen
WO1993000894A1 (en) * 1991-07-03 1993-01-21 Scott Nathan E Prostaglandin e2 treatment of impotence
US5422371A (en) * 1992-05-27 1995-06-06 Arch Development Corp. Methods and compositions for inhibiting 5α-reductase activity
US5370613A (en) * 1993-02-11 1994-12-06 Helmy; Ali M. Catheter apparatus for delivering drugs to the penis
CA2168260C (en) * 1993-07-28 2000-04-11 Marianna Foldvari Biphasic multilamellar lipid vesicles
US5419763B1 (en) * 1994-01-04 1997-07-15 Cor Trak Medical Inc Prostatic drug-delivery catheter
US5482039A (en) * 1994-03-25 1996-01-09 Vivus, Inc. Process for diagnosing erectile dysfunction, and related methods of treatment
EP0722323B1 (en) * 1994-08-05 1999-09-22 Inpharma S.A. Compositions containing troxerutine complexed with phosphatidylcholine for topical treatment of erectile impotence
GB9423910D0 (en) * 1994-11-26 1995-01-11 Pfizer Ltd Therapeutic agents

Also Published As

Publication number Publication date
AU1024297A (en) 1997-07-14
BR9612040A (pt) 1999-12-28
EP0874622A1 (en) 1998-11-04
US5718917A (en) 1998-02-17
JPH11504945A (ja) 1999-05-11
NO982727L (no) 1998-08-17
PL327400A1 (en) 1998-12-07
IL124841A0 (en) 1999-01-26
EE9800182A (et) 1998-12-15
AU722555B2 (en) 2000-08-03
NO982727D0 (no) 1998-06-12
CN1207671A (zh) 1999-02-10
EP0874622A4 (en) 1999-02-10
EA199800565A1 (ru) 1999-02-25
SK80998A3 (en) 1999-01-11
IS4767A (is) 1998-06-09
KR20000064392A (ko) 2000-11-06
WO1997022334A1 (en) 1997-06-26
TR199801104T2 (xx) 1998-10-21
HUP9902094A2 (hu) 1999-10-28

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
RH1 Patent not in force