IL124867A0 - 1, 4-dihydropyridine compounds as bradykinin antagonists - Google Patents

1, 4-dihydropyridine compounds as bradykinin antagonists

Info

Publication number
IL124867A0
IL124867A0 IL12486797A IL12486797A IL124867A0 IL 124867 A0 IL124867 A0 IL 124867A0 IL 12486797 A IL12486797 A IL 12486797A IL 12486797 A IL12486797 A IL 12486797A IL 124867 A0 IL124867 A0 IL 124867A0
Authority
IL
Israel
Prior art keywords
bradykinin antagonists
dihydropyridine compounds
dihydropyridine
compounds
bradykinin
Prior art date
Application number
IL12486797A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL124867A0 publication Critical patent/IL124867A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Otolaryngology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
IL12486797A 1996-02-19 1997-01-27 1, 4-dihydropyridine compounds as bradykinin antagonists IL124867A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB9600132 1996-02-19
PCT/IB1997/000058 WO1997030048A1 (en) 1996-02-19 1997-01-27 1,4-dihydropyridine compounds as bradykinin antagonists

Publications (1)

Publication Number Publication Date
IL124867A0 true IL124867A0 (en) 1999-01-26

Family

ID=11004406

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12486797A IL124867A0 (en) 1996-02-19 1997-01-27 1, 4-dihydropyridine compounds as bradykinin antagonists

Country Status (34)

Country Link
US (1) US6131226A (cs)
EP (1) EP0882044B1 (cs)
JP (1) JP3167335B2 (cs)
KR (1) KR19990082678A (cs)
CN (1) CN1211251A (cs)
AR (1) AR005841A1 (cs)
AT (1) ATE220676T1 (cs)
AU (1) AU1396497A (cs)
BG (1) BG102678A (cs)
BR (1) BR9707568A (cs)
CA (1) CA2245857C (cs)
CO (1) CO4650041A1 (cs)
CZ (1) CZ258698A3 (cs)
DE (1) DE69714019T2 (cs)
DK (1) DK0882044T3 (cs)
ES (1) ES2177921T3 (cs)
HN (1) HN1997000013A (cs)
HR (1) HRP970094A2 (cs)
HU (1) HUP9902810A3 (cs)
ID (1) ID16434A (cs)
IL (1) IL124867A0 (cs)
IS (1) IS4783A (cs)
MA (1) MA26419A1 (cs)
NO (1) NO983776D0 (cs)
NZ (1) NZ325455A (cs)
OA (1) OA10712A (cs)
PE (1) PE36298A1 (cs)
PL (1) PL328514A1 (cs)
PT (1) PT882044E (cs)
SI (1) SI0882044T1 (cs)
TN (1) TNSN97037A1 (cs)
TR (1) TR199801593T2 (cs)
WO (1) WO1997030048A1 (cs)
ZA (1) ZA971357B (cs)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11106375A (ja) * 1997-08-18 1999-04-20 Pfizer Pharmaceut Inc ブラジキニンアンタゴニストとしての光学的に活性な1,4−ジヒドロピリジン化合物
EP1110962A1 (en) * 1999-12-10 2001-06-27 Pfizer Inc. Process for preparing 1,4-dihydropyridine compounds
US6653313B2 (en) * 2000-08-10 2003-11-25 Warner-Lambert Company Llc 1,4-dihydropyridine compounds as bradykinin antagonists
GB0427281D0 (en) * 2004-12-14 2005-01-12 3M Innovative Properties Co Methods of providing medicinal metal components having through holes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5120750A (en) * 1989-01-17 1992-06-09 Synphar Laboratories, Inc. Generation of 1,4-dihydropyridine derivatives
WO1996006083A1 (en) 1994-08-24 1996-02-29 Pfizer Pharmaceuticals Inc. 2-(piperazinyl-1-carbonylmethyl)-1,4-dihydropyridines as bradykinin antagonists
MX9701245A (es) * 1996-02-19 1998-04-30 Pfizer Compuestos de 1,4 dihidropiridina.

Also Published As

Publication number Publication date
NO983776L (no) 1998-08-18
MA26419A1 (fr) 2004-12-20
JP3167335B2 (ja) 2001-05-21
CO4650041A1 (es) 1998-09-03
CA2245857A1 (en) 1997-08-21
TR199801593T2 (xx) 1999-12-21
ZA971357B (en) 1998-08-18
ES2177921T3 (es) 2002-12-16
CA2245857C (en) 2002-10-01
US6131226A (en) 2000-10-17
IS4783A (is) 1998-06-25
KR19990082678A (ko) 1999-11-25
HRP970094A2 (en) 1998-06-30
DE69714019T2 (de) 2002-11-14
AR005841A1 (es) 1999-07-14
BG102678A (en) 1999-04-30
DK0882044T3 (da) 2002-09-02
WO1997030048A1 (en) 1997-08-21
OA10712A (en) 2001-06-04
EP0882044A1 (en) 1998-12-09
ID16434A (id) 1997-09-25
BR9707568A (pt) 1999-07-27
NZ325455A (en) 1999-07-29
PL328514A1 (en) 1999-02-01
CZ258698A3 (cs) 1999-06-16
HUP9902810A2 (hu) 2000-05-28
PE36298A1 (es) 1998-07-18
TNSN97037A1 (fr) 2005-03-15
HUP9902810A3 (en) 2000-09-28
EP0882044B1 (en) 2002-07-17
HN1997000013A (es) 1997-06-26
JPH11507949A (ja) 1999-07-13
ATE220676T1 (de) 2002-08-15
NO983776D0 (no) 1998-08-18
AU1396497A (en) 1997-09-02
CN1211251A (zh) 1999-03-17
PT882044E (pt) 2002-11-29
SI0882044T1 (en) 2002-10-31
DE69714019D1 (de) 2002-08-22

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