IL126123A - Antibiotic cocktail and method of decontaminating a tissue for transplantation using said cocktail - Google Patents

Antibiotic cocktail and method of decontaminating a tissue for transplantation using said cocktail

Info

Publication number: IL126123A
Authority: IL; Israel
Prior art keywords: tissue; cocktail; antibiotic; decontaminating; transplantation
Prior art date: 1996-03-29

Application number

IL12612397A

Other languages

English (en)

Other versions

IL126123A0 (en

Original Assignee

Cryolife Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-03-29

Filing date

1997-03-24

Publication date

2001-01-28

1997-03-24 Application filed by Cryolife Inc filed Critical Cryolife Inc

1999-05-09 Publication of IL126123A0 publication Critical patent/IL126123A0/xx

2001-01-28 Publication of IL126123A publication Critical patent/IL126123A/xx

Links

230000003115 biocidal effect Effects 0.000 title abstract 3
238000000034 method Methods 0.000 title abstract 2
238000002054 transplantation Methods 0.000 title 1
239000003242 anti bacterial agent Substances 0.000 abstract 2
230000001580 bacterial effect Effects 0.000 abstract 2
230000002538 fungal effect Effects 0.000 abstract 2
230000001954 sterilising effect Effects 0.000 abstract 2
230000035899 viability Effects 0.000 abstract 2
APKFDSVGJQXUKY-KKGHZKTASA-N Amphotericin-B Natural products O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1C=CC=CC=CC=CC=CC=CC=C[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 APKFDSVGJQXUKY-KKGHZKTASA-N 0.000 abstract 1
APKFDSVGJQXUKY-INPOYWNPSA-N amphotericin B Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 APKFDSVGJQXUKY-INPOYWNPSA-N 0.000 abstract 1
229960003942 amphotericin b Drugs 0.000 abstract 1
229940121375 antifungal agent Drugs 0.000 abstract 1
239000003429 antifungal agent Substances 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
RFHAOTPXVQNOHP-UHFFFAOYSA-N fluconazole Chemical compound C1=NC=NN1CC(C=1C(=CC(F)=CC=1)F)(O)CN1C=NC=N1 RFHAOTPXVQNOHP-UHFFFAOYSA-N 0.000 abstract 1
229960004884 fluconazole Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/124—Disinfecting agents, e.g. antimicrobials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
- Y10S623/915—Method or apparatus for preparing biological material

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Environmental Sciences (AREA)
Zoology (AREA)
Dentistry (AREA)
Wood Science & Technology (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Apparatus For Disinfection Or Sterilisation (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Chemical Or Physical Treatment Of Fibers (AREA)
Materials For Medical Uses (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

IL12612397A 1996-03-29 1997-03-24 Antibiotic cocktail and method of decontaminating a tissue for transplantation using said cocktail IL126123A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/626,167 US5741782A (en)	1996-03-29	1996-03-29	Antibiotic cocktail and method of use
PCT/US1997/004700 WO1997036479A1 (en)	1996-03-29	1997-03-24	Antibiotic cocktail and method of use

Publications (2)

Publication Number	Publication Date
IL126123A0 IL126123A0 (en)	1999-05-09
IL126123A true IL126123A (en)	2001-01-28

Family

ID=24509238

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL12612397A IL126123A (en)	1996-03-29	1997-03-24	Antibiotic cocktail and method of decontaminating a tissue for transplantation using said cocktail

Country Status (14)

Country	Link
US (1)	US5741782A (de)
EP (1)	EP0889690B1 (de)
JP (1)	JP2000507953A (de)
CN (1)	CN1219103A (de)
AR (1)	AR002228A1 (de)
AT (1)	ATE232360T1 (de)
AU (1)	AU708060B2 (de)
BR (1)	BR9708306A (de)
CA (1)	CA2250036C (de)
DE (1)	DE69719019T2 (de)
DK (1)	DK0889690T3 (de)
ES (1)	ES2192676T3 (de)
IL (1)	IL126123A (de)
WO (1)	WO1997036479A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1294740B1 (it) *	1997-09-16	1999-04-12	Prospa Bv	Derivati della partricina per il trattamento profilattico e/o curativo delle contaminazioni fungine di colture cellulari e di tessuti
FR2790641B1 (fr) *	1999-03-10	2005-02-25	Cair L G L	Liquide de conservation de tissu humain ou animal, notamment de veines
EP1060772B1 (de)	1999-06-11	2012-02-01	Canon Kabushiki Kaisha	Vorrichtung und Verfahren zur Darstellung eines von mehreren Benutzern geteilten Raumes, wo Wirklichkeit zum Teil einbezogen wird, entsprechende Spielvorrichtung und entsprechendes Schnittstellenverfahren
JP2002128697A (ja) *	2000-10-20	2002-05-09	Nonomura Tomosuke	口腔治療予防剤
JP3363445B1 (ja) *	2001-04-23	2003-01-08	新田ゼラチン株式会社	生検採取細胞の培養方法および動物細胞培養用キット
JP2006528704A (ja) *	2003-05-27	2006-12-21	セラヴァンスインコーポレーテッド	グリコペプチド抗細菌剤と組み合わせたポリエンマクロライド抗真菌剤の使用
DE602004010915T2 (de) *	2003-07-22	2008-12-11	Theravance, Inc., South San Francisco	Verwendung eines antimykotischen echinocandin-mittels in kombination mit einem antibakteriellen glycopeptid-mittel
DE102004047247B3 (de) *	2004-09-22	2006-03-16	Auto Tissue Gmbh	Sterilisationsverfahren zur Herstellung von implantierbarem oder transplantierbarem biologischem Material
US20090018111A1 (en) *	2004-10-08	2009-01-15	Makoto Sunagawa	Novel Antimicrobial Medicament
US20080227732A1 (en) *	2005-05-13	2008-09-18	Venus Remedies Limited	Treatment and Control of Severe Infections Including Cystic Fibrosis
US20080306610A1 (en) *	2007-06-07	2008-12-11	Zimmer Orthobiologics, Inc.	Tissue processing for nonimmunogenic implants
WO2010105021A2 (en)	2009-03-11	2010-09-16	Cryolife, Inc.	Bioburden-reducing antibiotic composition and method of use
US8377143B2 (en)	2010-07-06	2013-02-19	Cryolife, Inc.	Tissue implants for implantation and methods for preparing the same
US8475827B2 (en)	2010-07-06	2013-07-02	Cryolife, Inc.	Tissue implants for implantation and methods for preparing the same
DE102010034330B4 (de)	2010-08-14	2013-10-31	Cytonet Gmbh & Co. Kg	Verfahren zur Herstellung desinfizierter humaner Zellsuspensionen
US8435305B2 (en)	2010-08-31	2013-05-07	Zimmer, Inc.	Osteochondral graft delivery device and uses thereof
IL273388B2 (en) *	2017-09-20	2025-10-01	Atopic Medical Llc	Preparations and methods for treating and improving respiratory conditions and mucosal inflammation
CN111034711B (zh) *	2019-12-19	2022-04-05	海南一龄医疗产业发展有限公司	高效清除细胞培养过程中微生物污染的组合物及方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4695536A (en) *	1984-01-10	1987-09-22	Lindstrom Richard L	Corneal storage system
US4890457A (en) *	1987-01-02	1990-01-02	Cryolife, Inc.	Method for cryopreserving heart valves
JP2581707B2 (ja) *	1987-10-02	1997-02-12	科研製薬株式会社	抗真菌剤組成物
US4988697A (en) *	1989-07-28	1991-01-29	Merck & Co., Inc.	Fungicidal compositions and method
EP0424159A3 (en) *	1989-10-19	1991-11-06	Osteotech, Inc.,	Aseptic processing of allograft bone and tissue
WO1992012632A1 (en) *	1991-01-24	1992-08-06	Cryolife, Inc.	Tissue cryopreservation method

1996
- 1996-03-29 US US08/626,167 patent/US5741782A/en not_active Expired - Lifetime
1997
- 1997-03-24 ES ES97916935T patent/ES2192676T3/es not_active Expired - Lifetime
- 1997-03-24 DE DE69719019T patent/DE69719019T2/de not_active Expired - Fee Related
- 1997-03-24 CA CA002250036A patent/CA2250036C/en not_active Expired - Fee Related
- 1997-03-24 EP EP97916935A patent/EP0889690B1/de not_active Expired - Lifetime
- 1997-03-24 AT AT97916935T patent/ATE232360T1/de not_active IP Right Cessation
- 1997-03-24 CN CN97194759A patent/CN1219103A/zh active Pending
- 1997-03-24 DK DK97916935T patent/DK0889690T3/da active
- 1997-03-24 JP JP9535345A patent/JP2000507953A/ja not_active Ceased
- 1997-03-24 BR BR9708306A patent/BR9708306A/pt active Search and Examination
- 1997-03-24 AU AU25418/97A patent/AU708060B2/en not_active Ceased
- 1997-03-24 IL IL12612397A patent/IL126123A/xx not_active IP Right Cessation
- 1997-03-24 WO PCT/US1997/004700 patent/WO1997036479A1/en not_active Ceased
- 1997-03-31 AR ARP970101284A patent/AR002228A1/es unknown

Also Published As

Publication number	Publication date
CA2250036A1 (en)	1997-10-09
EP0889690A1 (de)	1999-01-13
AR002228A1 (es)	1998-03-11
JP2000507953A (ja)	2000-06-27
DK0889690T3 (da)	2003-06-10
EP0889690A4 (de)	2001-07-18
DE69719019T2 (de)	2003-12-11
EP0889690B1 (de)	2003-02-12
WO1997036479A1 (en)	1997-10-09
BR9708306A (pt)	1999-08-03
DE69719019D1 (de)	2003-03-20
AU2541897A (en)	1997-10-22
ATE232360T1 (de)	2003-02-15
CN1219103A (zh)	1999-06-09
CA2250036C (en)	2002-03-19
ES2192676T3 (es)	2003-10-16
IL126123A0 (en)	1999-05-09
US5741782A (en)	1998-04-21
AU708060B2 (en)	1999-07-29

Legal Events

Date	Code	Title
2001-06-14	FF	Patent granted
2001-07-24	KB	Patent renewed
2003-06-24	KB	Patent renewed
2007-07-24	KB	Patent renewed
2011-04-28	KB	Patent renewed
2015-03-31	KB	Patent renewed
2017-10-31	EXP	Patent expired

Publication	Publication Date	Title
IL126123A (en)	2001-01-28	Antibiotic cocktail and method of decontaminating a tissue for transplantation using said cocktail
WO2002091824A3 (en)	2003-04-24	Biological-chemical fungicide compositions and methods of use
TR199902765T2 (xx)	2000-07-21	Bitki hastal�klar�, m�s�r kurduyla m�cadelede yeni bac�llus t�r�.
AU2722802A (en)	2002-06-18	Bacterial inoculants for enhancing plant growth
ZA200007545B (en)	2001-09-03	Method and composition for inhibiting growth of micro-organisms including peracetic acid and a non-oxidizing biocide.
AU8030791A (en)	1992-01-16	Compositions having improved antibacterial properties and use of such compositions in suppressing growth of micro-organisms, e.g. listeria bacteria
DE60216613D1 (de)	2007-01-18	Bioimpfungszusammensetzung enthaltend bakterien der arten b.subtilis oder b.lentimorbus von kuhmilch
WO2000015247A3 (en)	2000-05-25	Methods of treating multiple myeloma and myeloma-induced bone resorption using integrin antagonists
FI871918A7 (fi)	1987-11-03	Koostumus ja menetelmä mikrobikasvun estämiseksi.
PL340370A1 (en)	2001-01-29	Pesticide against pathogenic micro-organism attacking plants
EP0703725A4 (de)	1998-06-10	Verfahren zur bekampfung von pilzen, hefe und bakterien mit ausgewählten monozyklischen terpenen
DE19681757T1 (de)	1999-05-12	Verfahren zur Bekämpfung von mikrobiellen Verunreinigungen bei Lebensmittelverarbeitungseinrichtungen unter Verwendung von Ozonisierung
ES2047089T3 (es)	1994-02-16	Un procedimiento para conservar forraje.
WO2001052655A3 (en)	2002-03-28	Materials and methods for biological control of soilborne pathogens
AU2001238332A1 (en)	2001-09-03	Method of sterilizing articles
EP1110454A3 (de)	2002-06-05	5-Carboxanilido-haloalkylthiazole als antimikrobielle Mittel und als marine Antifouling-Mittel
TW349124B (en)	1999-01-01	Osmotically controlled fermentation process for the preparation of acarbose
ATE260097T1 (de)	2004-03-15	Hopfensäuren zur hemmung von staphylococcus aureus
IT1316985B1 (it)	2003-05-26	Terreno di coltura per la coltura di lactobacillus clearans e metodoper la conservazione di detto ceppo batterico.
AU2395795A (en)	1995-11-29	Methods for inhibiting or reducing mucositis associated with bone marrow transplant or pheripheral stem cell infusion therapies
IL148345A0 (en)	2002-09-12	Methods of and compositions for inhibiting the proliferation of mammalian cells
WO2001047360A3 (en)	2001-12-13	Methods for treating plants with cyclic glycosides
AU4252097A (en)	1998-03-26	Vitrification solutions for shelf preservation of cells, tissues, organs and organisms
IL174545A0 (en)	2006-08-01	Hair growth inhibition
AU5022399A (en)	2000-02-21	Methods and compositions for inhibiting microbial growth in wine