IL129028A0 - Method for in vitro determination of erythropoietin bioactivity - Google Patents
Method for in vitro determination of erythropoietin bioactivityInfo
- Publication number
- IL129028A0 IL129028A0 IL12902896A IL12902896A IL129028A0 IL 129028 A0 IL129028 A0 IL 129028A0 IL 12902896 A IL12902896 A IL 12902896A IL 12902896 A IL12902896 A IL 12902896A IL 129028 A0 IL129028 A0 IL 129028A0
- Authority
- IL
- Israel
- Prior art keywords
- epo
- sample
- vitro
- cells
- activity
- Prior art date
Links
- 238000000338 in vitro Methods 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 102000003951 Erythropoietin Human genes 0.000 title 1
- 108090000394 Erythropoietin Proteins 0.000 title 1
- 229940105423 erythropoietin Drugs 0.000 title 1
- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 title 1
- 206010073071 hepatocellular carcinoma Diseases 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 230000035899 viability Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/746—Erythropoetin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1996/015049 WO1998012558A1 (en) | 1996-09-20 | 1996-09-20 | Methods for in vitro determination of erythropoietin bioactivity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL129028A0 true IL129028A0 (en) | 2000-02-17 |
Family
ID=22255824
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12902896A IL129028A0 (en) | 1996-09-20 | 1996-09-20 | Method for in vitro determination of erythropoietin bioactivity |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0935752B1 (de) |
| JP (1) | JP3764487B2 (de) |
| KR (1) | KR100295506B1 (de) |
| AT (1) | ATE209354T1 (de) |
| AU (1) | AU715237B2 (de) |
| CA (1) | CA2265989C (de) |
| DE (1) | DE69618630T2 (de) |
| DK (1) | DK0935752T3 (de) |
| ES (1) | ES2168509T3 (de) |
| IL (1) | IL129028A0 (de) |
| NO (1) | NO321047B1 (de) |
| PT (1) | PT935752E (de) |
| WO (1) | WO1998012558A1 (de) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL73544A (en) * | 1984-11-19 | 1988-11-15 | Yissum Res Dev Co | In vitro bioassay of erythropoietin in the absence of serum involving dna synthesis by erythroid precursors |
| AU4104889A (en) * | 1988-09-07 | 1990-03-15 | Bioclones (Pty) Ltd | Purification of erythropoietin |
| JP2750600B2 (ja) * | 1989-02-17 | 1998-05-13 | 雪印乳業株式会社 | エリスロポエチンの生物活性測定方法 |
| WO1992006116A1 (en) * | 1990-09-28 | 1992-04-16 | Ortho Pharmaceutical Corporation | Hybrid growth factors |
-
1996
- 1996-09-20 CA CA2265989A patent/CA2265989C/en not_active Expired - Lifetime
- 1996-09-20 DE DE69618630T patent/DE69618630T2/de not_active Expired - Lifetime
- 1996-09-20 IL IL12902896A patent/IL129028A0/xx unknown
- 1996-09-20 DK DK96933065T patent/DK0935752T3/da active
- 1996-09-20 AT AT96933065T patent/ATE209354T1/de active
- 1996-09-20 EP EP96933065A patent/EP0935752B1/de not_active Expired - Lifetime
- 1996-09-20 ES ES96933065T patent/ES2168509T3/es not_active Expired - Lifetime
- 1996-09-20 WO PCT/US1996/015049 patent/WO1998012558A1/en not_active Ceased
- 1996-09-20 PT PT96933065T patent/PT935752E/pt unknown
- 1996-09-20 JP JP51461298A patent/JP3764487B2/ja not_active Expired - Lifetime
- 1996-09-20 AU AU71626/96A patent/AU715237B2/en not_active Expired
-
1999
- 1999-03-19 NO NO19991338A patent/NO321047B1/no not_active IP Right Cessation
- 1999-03-19 KR KR1019997002377A patent/KR100295506B1/ko not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| NO321047B1 (no) | 2006-03-06 |
| PT935752E (pt) | 2002-03-28 |
| AU715237B2 (en) | 2000-01-20 |
| KR100295506B1 (ko) | 2001-08-07 |
| ES2168509T3 (es) | 2002-06-16 |
| CA2265989C (en) | 2010-11-02 |
| DE69618630D1 (de) | 2002-02-21 |
| EP0935752A1 (de) | 1999-08-18 |
| DE69618630T2 (de) | 2002-05-08 |
| KR20000048492A (ko) | 2000-07-25 |
| JP3764487B2 (ja) | 2006-04-05 |
| ATE209354T1 (de) | 2001-12-15 |
| CA2265989A1 (en) | 1998-03-26 |
| WO1998012558A1 (en) | 1998-03-26 |
| EP0935752B1 (de) | 2001-11-21 |
| NO991338L (no) | 1999-03-19 |
| NO991338D0 (no) | 1999-03-19 |
| DK0935752T3 (da) | 2002-05-21 |
| AU7162696A (en) | 1998-04-14 |
| JP2001500736A (ja) | 2001-01-23 |
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