IL134669A0 - Butyrate derivatives in the treatment of fibromyalgia and chronic fatigue syndrome - Google Patents
Butyrate derivatives in the treatment of fibromyalgia and chronic fatigue syndromeInfo
- Publication number
- IL134669A0 IL134669A0 IL13466998A IL13466998A IL134669A0 IL 134669 A0 IL134669 A0 IL 134669A0 IL 13466998 A IL13466998 A IL 13466998A IL 13466998 A IL13466998 A IL 13466998A IL 134669 A0 IL134669 A0 IL 134669A0
- Authority
- IL
- Israel
- Prior art keywords
- fibromyalgia
- chronic fatigue
- treatment
- fatigue syndrome
- butyrate derivatives
- Prior art date
Links
- 206010008874 Chronic Fatigue Syndrome Diseases 0.000 title abstract 3
- 150000004648 butanoic acid derivatives Chemical class 0.000 title abstract 2
- 208000029766 myalgic encephalomeyelitis/chronic fatigue syndrome Diseases 0.000 title abstract 2
- 208000001640 Fibromyalgia Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Anesthesiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/920,979 US5990162A (en) | 1997-08-29 | 1997-08-29 | Method for treatment of fibromyalgia and chronic fatigue syndrome |
| PCT/US1998/017818 WO1999009972A1 (en) | 1997-08-29 | 1998-08-27 | Butyrate derivatives in the treatment of fibromyalgia and chronic fatigue syndrome |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL134669A0 true IL134669A0 (en) | 2001-04-30 |
Family
ID=25444733
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13466998A IL134669A0 (en) | 1997-08-29 | 1998-08-27 | Butyrate derivatives in the treatment of fibromyalgia and chronic fatigue syndrome |
| IL134669A IL134669A (en) | 1997-08-29 | 2000-02-22 | Use of butyrate derivatives for preparing medicaments for the treatment of fibromyalgia and chronic fatigue syndrome |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL134669A IL134669A (en) | 1997-08-29 | 2000-02-22 | Use of butyrate derivatives for preparing medicaments for the treatment of fibromyalgia and chronic fatigue syndrome |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5990162A (de) |
| EP (1) | EP1017381B1 (de) |
| JP (1) | JP3660587B2 (de) |
| AT (1) | ATE289508T1 (de) |
| AU (1) | AU737086B2 (de) |
| CA (1) | CA2301723C (de) |
| CZ (1) | CZ295248B6 (de) |
| DE (1) | DE69829112T2 (de) |
| ES (1) | ES2235355T3 (de) |
| IL (2) | IL134669A0 (de) |
| NO (1) | NO326479B1 (de) |
| NZ (1) | NZ502983A (de) |
| PT (1) | PT1017381E (de) |
| WO (1) | WO1999009972A1 (de) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1316309A1 (de) * | 1998-12-23 | 2003-06-04 | Orphan Medical Inc. | Mikrobenbeständige und stabilisierte Lösungen die gamma-Hydroxybuttersäuresalze zur Behandlung von Narkolepsie enthalten |
| CA2355293C (en) * | 1998-12-23 | 2005-08-16 | Orphan Medical, Inc. | Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy |
| JP5031144B2 (ja) | 1999-03-25 | 2012-09-19 | メタボリックス,インコーポレイテッド | ポリヒドロキシアルカノエートポリマーの医療デバイスおよび医療適用 |
| US6610324B2 (en) * | 1999-04-07 | 2003-08-26 | The Mclean Hospital Corporation | Flupirtine in the treatment of fibromyalgia and related conditions |
| WO2001019361A2 (en) * | 1999-09-14 | 2001-03-22 | Tepha, Inc. | Therapeutic uses of polymers and oligomers comprising gamma-hydroxybutyrate |
| ES2383673T3 (es) | 2000-09-22 | 2012-06-25 | Jpi Commercial, Llc | Composiciones de gamma-hidroxibutirato que contienen portadores de hidrato de carbonos |
| US7553829B2 (en) * | 2000-11-30 | 2009-06-30 | Humanetics Corporation | Treatment of chronic fatigue syndrome and fibromyalgia syndrome |
| JP2005510482A (ja) * | 2001-10-16 | 2005-04-21 | アストラゼネカ・アクチエボラーグ | 線維筋痛症候群の治療方法 |
| WO2009097526A2 (en) * | 2008-01-30 | 2009-08-06 | Great Lakes Biosciences, Llc | Brain-related chronic pain disorder treatment method and apparatus |
| US6703216B2 (en) | 2002-03-14 | 2004-03-09 | The Regents Of The University Of California | Methods, compositions and apparatuses for detection of gamma-hydroxybutyric acid (GHB) |
| ES2527857T3 (es) | 2003-05-08 | 2015-01-30 | Tepha, Inc. | Tejidos y fibras médicas de polihidroxialcanoato |
| PT1778305E (pt) | 2004-08-03 | 2010-07-27 | Tepha Inc | Suturas de poli-hidroxialcanoato que no se enrolam |
| KR20070100686A (ko) * | 2004-09-07 | 2007-10-11 | 오르펀 메디칼, 인크. | 개선된 ghb 조성물 |
| KR20070085838A (ko) * | 2004-11-10 | 2007-08-27 | 더 트러스티이스 오브 콜롬비아 유니버시티 인 더 시티 오브 뉴욕 | 운동 장애의 치료 방법 |
| US20080293698A1 (en) * | 2005-05-16 | 2008-11-27 | Joseph Johnson | Methods and Compositions for Treating Arg |
| US7838556B2 (en) * | 2006-02-21 | 2010-11-23 | University Of Maryland, Baltimore | Ethers of 3-hydroxyphenylacetic acid as selective gamma-hydroxybutyric acid receptor ligands |
| US7943683B2 (en) | 2006-12-01 | 2011-05-17 | Tepha, Inc. | Medical devices containing oriented films of poly-4-hydroxybutyrate and copolymers |
| CN102099033B (zh) * | 2008-05-16 | 2012-10-24 | 阿克西斯股份有限公司 | 用于治疗纤维肌痛症的药物组合物 |
| US8778398B2 (en) * | 2008-11-04 | 2014-07-15 | Jazz Pharmaceuticals, Inc. | Immediate release formulations and dosage forms of gamma-hydroxybutyrate |
| US8771735B2 (en) * | 2008-11-04 | 2014-07-08 | Jazz Pharmaceuticals, Inc. | Immediate release dosage forms of sodium oxybate |
| EP2421808B1 (en) | 2009-04-23 | 2013-07-31 | Concert Pharmaceuticals Inc. | 4-hydroxybutyric acid analogs |
| CA2794171C (en) | 2010-03-24 | 2018-07-03 | Jazz Pharmaceuticals, Inc. | Controlled release dosage forms for high dose, water soluble and hygroscopic drug substances |
| CA2732479A1 (en) * | 2011-02-14 | 2012-08-14 | Concert Pharmaceuticals, Inc. | 4-hydroxybutyric acid analogs |
| KR101976218B1 (ko) * | 2011-02-14 | 2019-05-07 | 콘서트 파마슈티컬즈, 인크. | 4-히드록시부티르산 중수소화 유사체 |
| EP2961738B1 (de) | 2012-11-14 | 2019-12-25 | CJ CheilJedang Corporation | Herstellung von salzen von 4-hydroxybutyrate mittels biobasierter rohstoffe |
| US8591922B1 (en) | 2012-12-14 | 2013-11-26 | Jazz Pharmacuticals, Inc. | Gamma-hydroxybutyrate compositions and their use for the treatment of disorders |
| US9050302B2 (en) | 2013-03-01 | 2015-06-09 | Jazz Pharmaceuticals Ireland Limited | Method of administration of gamma hydroxybutyrate with monocarboxylate transporters |
| EP3180040B1 (de) | 2014-08-15 | 2020-05-13 | Tepha, Inc. | Selbsthaltendes chirurgisches nahtmaterial aus poly-4-hydroxybutyrat und copolymeren davon |
| US10626521B2 (en) | 2014-12-11 | 2020-04-21 | Tepha, Inc. | Methods of manufacturing mesh sutures from poly-4-hydroxybutyrate and copolymers thereof |
| WO2016094669A1 (en) | 2014-12-11 | 2016-06-16 | Tepha, Inc. | Methods of orienting multifilament yarn and monofilaments of poly-4-hydroxybutyrate and copolymers thereof |
| WO2016102407A1 (en) | 2014-12-22 | 2016-06-30 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device with electromagnetic drive unit |
| US10398662B1 (en) | 2015-02-18 | 2019-09-03 | Jazz Pharma Ireland Limited | GHB formulation and method for its manufacture |
| FR3049463B1 (fr) | 2016-04-01 | 2019-07-05 | Debregeas Et Associes Pharma | Doses unitaires a liberation immediate de ghb ou de l'un de ses sels therapeutiquement acceptables administrees par voie orale et leur utilisation pour maintenir l'abstinence alcoolique |
| US11986451B1 (en) | 2016-07-22 | 2024-05-21 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11504347B1 (en) | 2016-07-22 | 2022-11-22 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US12478604B1 (en) | 2016-07-22 | 2025-11-25 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| UY37341A (es) | 2016-07-22 | 2017-11-30 | Flamel Ireland Ltd | Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada |
| US12186296B1 (en) | 2016-07-22 | 2025-01-07 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11602512B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11602513B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US20180263936A1 (en) | 2017-03-17 | 2018-09-20 | Jazz Pharmaceuticals Ireland Limited | Gamma-hydroxybutyrate compositions and their use for the treatment of disorders |
| CA3085941A1 (en) | 2017-12-18 | 2019-06-27 | Tris Pharma, Inc. | Ghb pharmaceutical compositions comprising a floating interpenetrating polymer network forming system |
| CA3097737A1 (en) | 2017-12-18 | 2019-06-27 | Tris Pharma, Inc. | Pharmaceutical compositions comprising a floating interpenetrating polymer network forming system |
| WO2019126214A1 (en) | 2017-12-18 | 2019-06-27 | Tris Pharma, Inc. | Pharmaceutical composition comprising ghb gastro-retentive raft forming systems having trigger pulse drug release |
| AU2018388577B2 (en) | 2017-12-18 | 2024-06-06 | Tris Pharma, Inc. | Modified release drug powder composition comprising gastro-retentive raft forming systems having trigger pulse drug release |
| CA3115122A1 (en) | 2018-11-19 | 2020-05-28 | Jazz Pharmaceuticals Ireland Limited | Alcohol-resistant drug formulations |
| EP3930702A1 (de) | 2019-03-01 | 2022-01-05 | Flamel Ireland Limited | Gamma-hydroxybutyratzusammensetzungen mit verbesserter pharmakokinetik im zugeführten zustand |
| TW202139986A (zh) | 2020-02-21 | 2021-11-01 | 愛爾蘭商爵士製藥愛爾蘭有限責任公司 | 治療原發性嗜睡症之方法 |
| WO2022076824A1 (en) | 2020-10-08 | 2022-04-14 | Jazz Pharmaceuticals Ireland Limited | Sodium oxybate to treat idiopathic hypersomnia |
| EP4228620A2 (de) | 2020-10-16 | 2023-08-23 | Jazz Pharmaceuticals Ireland Limited | Behandlungsverfahren mit ghb |
| US11583510B1 (en) | 2022-02-07 | 2023-02-21 | Flamel Ireland Limited | Methods of administering gamma hydroxybutyrate formulations after a high-fat meal |
| US11779557B1 (en) | 2022-02-07 | 2023-10-10 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| JP2026513019A (ja) | 2023-02-03 | 2026-04-22 | トリス・フアルマ・インコーポレーテツド | 1晩1回の低ナトリウムオキシベート組成物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60168044A (ja) * | 1984-02-10 | 1985-08-31 | Sharp Corp | 感湿素子 |
| US4738985A (en) * | 1986-03-19 | 1988-04-19 | The University Of Toronto Innovations Foundations | Pharmaceutical composition and treatment |
| JPH05262654A (ja) * | 1992-03-18 | 1993-10-12 | Kaken Pharmaceut Co Ltd | 慢性疲労症候群治療剤 |
| ITTO930510A1 (it) * | 1993-07-09 | 1993-10-07 | Walter Tarello | Farmaci attivi contro la chronic fatigue syndrome (c.f.s.) |
| IT1266565B1 (it) * | 1993-07-22 | 1997-01-09 | Ct Lab Farm Srl | Composizioni farmaceutiche a rilascio controllato a base di uno o piu' sali farmaceuticamente accettabili dell'acido gamma-idrossi-butirrico. |
| US5840331A (en) * | 1995-06-07 | 1998-11-24 | Arch Development Corporation | Use of γ-hydroxybutyrate for the stimulation of sleep-related secretion growth hormone and prolactin |
-
1997
- 1997-08-29 US US08/920,979 patent/US5990162A/en not_active Expired - Lifetime
-
1998
- 1998-08-27 PT PT98941094T patent/PT1017381E/pt unknown
- 1998-08-27 EP EP98941094A patent/EP1017381B1/de not_active Expired - Lifetime
- 1998-08-27 WO PCT/US1998/017818 patent/WO1999009972A1/en not_active Ceased
- 1998-08-27 DE DE69829112T patent/DE69829112T2/de not_active Expired - Fee Related
- 1998-08-27 CA CA002301723A patent/CA2301723C/en not_active Expired - Fee Related
- 1998-08-27 AT AT98941094T patent/ATE289508T1/de active
- 1998-08-27 NZ NZ502983A patent/NZ502983A/en not_active IP Right Cessation
- 1998-08-27 IL IL13466998A patent/IL134669A0/xx active IP Right Grant
- 1998-08-27 AU AU89237/98A patent/AU737086B2/en not_active Ceased
- 1998-08-27 CZ CZ2000741A patent/CZ295248B6/cs not_active IP Right Cessation
- 1998-08-27 ES ES98941094T patent/ES2235355T3/es not_active Expired - Lifetime
- 1998-08-27 JP JP2000507362A patent/JP3660587B2/ja not_active Expired - Fee Related
-
2000
- 2000-02-22 IL IL134669A patent/IL134669A/en not_active IP Right Cessation
- 2000-02-28 NO NO20000989A patent/NO326479B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL134669A (en) | 2006-08-20 |
| DE69829112T2 (de) | 2005-08-25 |
| CA2301723A1 (en) | 1999-03-04 |
| AU8923798A (en) | 1999-03-16 |
| CA2301723C (en) | 2008-02-19 |
| ATE289508T1 (de) | 2005-03-15 |
| WO1999009972A1 (en) | 1999-03-04 |
| AU737086B2 (en) | 2001-08-09 |
| CZ295248B6 (cs) | 2005-06-15 |
| JP2001513552A (ja) | 2001-09-04 |
| DE69829112D1 (de) | 2005-03-31 |
| EP1017381B1 (de) | 2005-02-23 |
| EP1017381A1 (de) | 2000-07-12 |
| NO326479B1 (no) | 2008-12-15 |
| PT1017381E (pt) | 2005-06-30 |
| NO20000989D0 (no) | 2000-02-28 |
| US5990162A (en) | 1999-11-23 |
| ES2235355T3 (es) | 2005-07-01 |
| HK1029278A1 (en) | 2001-03-30 |
| NO20000989L (no) | 2000-04-03 |
| NZ502983A (en) | 2001-08-31 |
| CZ2000741A3 (cs) | 2000-09-13 |
| JP3660587B2 (ja) | 2005-06-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed |