IL135232A - 21-hydroxy-6 19-oxidoprogesterone for treating excess of glucocorticoids - Google Patents

21-hydroxy-6 19-oxidoprogesterone for treating excess of glucocorticoids

Info

Publication number: IL135232A
Authority: IL; Israel
Prior art keywords: oxidoprogesterone; glucocorticoids; hydroxy; treating excess; excess
Prior art date: 1997-09-23

Application number

IL13523298A

Other languages

English (en)

Other versions

IL135232A0 (en

Original Assignee

Applied Research Systems

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-09-23

Filing date

1998-09-22

Publication date

2005-05-17

1998-09-22 Application filed by Applied Research Systems filed Critical Applied Research Systems

2001-05-20 Publication of IL135232A0 publication Critical patent/IL135232A0/xx

2005-05-17 Publication of IL135232A publication Critical patent/IL135232A/xx

Links

FIHWBGCIKMXLBI-NXMWLWCLSA-N (8s,9s,10s,13s,14s,17s)-17-acetyl-10-(hydroxymethyl)-13-methyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one Chemical compound C1CC2=CC(=O)CC[C@]2(CO)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 FIHWBGCIKMXLBI-NXMWLWCLSA-N 0.000 title 1
239000003862 glucocorticoid Substances 0.000 title 1
229940037128 systemic glucocorticoids Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/46—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of glucocorticosteroids

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Endocrinology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IL13523298A 1997-09-23 1998-09-22 21-hydroxy-6 19-oxidoprogesterone for treating excess of glucocorticoids IL135232A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP97116526A EP0903146A1 (fr)	1997-09-23	1997-09-23	21-Hydroy-6,19oxidoprogestérone (21-OH-60P) en tant qu'antiglucocorticoide
PCT/EP1998/006021 WO1999015181A1 (fr)	1997-09-23	1998-09-22	21-hydroxy-6,19-oxydoprogesterone(21oh-6op) et son utilisation en tant que medicament destine a traiter l'exces de glucocorticoides

Publications (2)

Publication Number	Publication Date
IL135232A0 IL135232A0 (en)	2001-05-20
IL135232A true IL135232A (en)	2005-05-17

Family

ID=8227390

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL13523298A IL135232A (en)	1997-09-23	1998-09-22	21-hydroxy-6 19-oxidoprogesterone for treating excess of glucocorticoids

Country Status (13)

Country	Link
US (1)	US6303591B1 (fr)
EP (2)	EP0903146A1 (fr)
AR (1)	AR023008A1 (fr)
AT (1)	ATE215373T1 (fr)
AU (1)	AU738522B2 (fr)
CA (1)	CA2303817C (fr)
DE (1)	DE69804659T2 (fr)
DK (1)	DK1033990T3 (fr)
ES (1)	ES2172937T3 (fr)
IL (1)	IL135232A (fr)
PT (1)	PT1033990E (fr)
WO (1)	WO1999015181A1 (fr)
ZA (1)	ZA988674B (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MXPA01011018A (es)	1999-04-30	2002-05-06	Pfizer Prod Inc	Moduladores del receptor glucocorticoide.
US7713989B2 (en)	2000-04-27	2010-05-11	Dow Robert L	Glucocorticoid receptor modulators
SI1330468T1 (sl) *	2000-09-18	2007-10-31	Serono Lab	Ĺ˝veplovi analogi 21-hidroksi-6,19-oksido-progesterona (21oh-6op) za zdravljenje preseĺ˝ka glukokortikoidov
SI1325022T1 (sl) *	2000-09-18	2007-04-30	Applied Research Systems	Metoda za pripravo 21-hidroksi-6,19-oksidoprogesterona (21oh-6op)
ES2246292T3 (es)	2000-10-30	2006-02-16	Pfizer Products Inc.	Moduladores de receptor glucocorticoide.
US8097606B2 (en) *	2003-07-23	2012-01-17	Corcept Therapeutics, Inc.	Antiglucocorticoids for the treatment of catatonia
EP1886695A1 (fr) *	2006-06-27	2008-02-13	Speedel Experimenta AG	Combinaisons pharmacéutiques avec inhibiteurs de l'aldosterone synthase et antagonistes du recepteur de glucocorticoides où inhibiteurs de la synthese de cortisol où antagonistes du facteur de libération de la corticotropine
ES2581765T3 (es)	2006-08-24	2016-09-07	University Of Tennessee Research Foundation	Acilanilidas sustituidas y métodos de uso de las mismas
EP2576582B1 (fr)	2010-05-26	2019-09-18	Corcept Therapeutics, Inc.	Traitement de la dystrophie musculaire
US10314807B2 (en)	2012-07-13	2019-06-11	Gtx, Inc.	Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
US9969683B2 (en)	2012-07-13	2018-05-15	Gtx, Inc.	Method of treating estrogen receptor (ER)-positive breast cancers with selective androgen receptor modulator (SARMS)
US9622992B2 (en)	2012-07-13	2017-04-18	Gtx, Inc.	Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
US9744149B2 (en)	2012-07-13	2017-08-29	Gtx, Inc.	Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
US10258596B2 (en)	2012-07-13	2019-04-16	Gtx, Inc.	Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
LT2872482T (lt)	2012-07-13	2020-12-28	Oncternal Therapeutics, Inc.	Krūties vėžių gydymo būdas selektyviu androgeno receptoriaus moduliatoriumi
US10987334B2 (en)	2012-07-13	2021-04-27	University Of Tennessee Research Foundation	Method of treating ER mutant expressing breast cancers with selective androgen receptor modulators (SARMs)
CN107530435A (zh)	2015-03-02	2018-01-02	科赛普特治疗学股份有限公司	使用糖皮质激素受体拮抗剂和生长抑素治疗acth分泌型肿瘤
WO2016160969A1 (fr)	2015-03-30	2016-10-06	Corcept Therapeutics, Inc.	Utilisation d'antagonistes de récepteurs de glucocorticoïdes en association avec des glucocorticoïdes pour traiter une insuffisance surrénale
ES2865334T3 (es)	2015-08-13	2021-10-15	Corcept Therapeutics Inc	Método de diagnóstico diferencial de síndrome de Cushing dependiente de ACTH
CA3011728A1 (fr)	2016-01-19	2017-07-27	Corcept Therapeutics, Inc.	Diagnostic differentiel du syndrome de cushing ectopique
AU2018289307B2 (en)	2017-06-20	2024-02-01	Corcept Therapeutics, Inc.	Methods of treating neuroepithelial tumors using selective glucocorticoid receptor modulators
CA3125151A1 (fr) *	2018-12-28	2020-07-02	Panda Consulting Llc	Modulateurs selectifs du recepteur des glucocorticoides a action courte
AU2020239920A1 (en)	2019-03-18	2021-11-04	Arnold L. Newman	Method of improving insulin sensitivity

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL118974A (en) *	1995-08-17	2001-09-13	Akzo Nobel Nv	History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them
ATE332696T1 (de) *	1997-10-06	2006-08-15	Univ Leland Stanford Junior	Methode zur behandlung von durch glycocorticoidstörungen verursachten psychosen

1997
- 1997-09-23 EP EP97116526A patent/EP0903146A1/fr not_active Withdrawn
1998
- 1998-09-22 EP EP98956833A patent/EP1033990B1/fr not_active Expired - Lifetime
- 1998-09-22 CA CA002303817A patent/CA2303817C/fr not_active Expired - Fee Related
- 1998-09-22 AU AU13341/99A patent/AU738522B2/en not_active Ceased
- 1998-09-22 DE DE69804659T patent/DE69804659T2/de not_active Expired - Fee Related
- 1998-09-22 DK DK98956833T patent/DK1033990T3/da active
- 1998-09-22 WO PCT/EP1998/006021 patent/WO1999015181A1/fr not_active Ceased
- 1998-09-22 IL IL13523298A patent/IL135232A/xx not_active IP Right Cessation
- 1998-09-22 PT PT98956833T patent/PT1033990E/pt unknown
- 1998-09-22 AR ARP980104727A patent/AR023008A1/es unknown
- 1998-09-22 AT AT98956833T patent/ATE215373T1/de not_active IP Right Cessation
- 1998-09-22 ES ES98956833T patent/ES2172937T3/es not_active Expired - Lifetime
- 1998-09-22 ZA ZA988674A patent/ZA988674B/xx unknown
2000
- 2000-03-23 US US09/533,225 patent/US6303591B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AU738522B2 (en)	2001-09-20
WO1999015181A1 (fr)	1999-04-01
EP1033990B1 (fr)	2002-04-03
AR023008A1 (es)	2002-09-04
IL135232A0 (en)	2001-05-20
AU1334199A (en)	1999-04-12
EP0903146A1 (fr)	1999-03-24
CA2303817A1 (fr)	1999-04-01
EP1033990A1 (fr)	2000-09-13
US6303591B1 (en)	2001-10-16
DE69804659T2 (de)	2002-10-02
DE69804659D1 (de)	2002-05-08
ES2172937T3 (es)	2002-10-01
ATE215373T1 (de)	2002-04-15
CA2303817C (fr)	2008-04-01
ZA988674B (en)	1999-06-28
DK1033990T3 (da)	2002-07-08
PT1033990E (pt)	2002-07-31

Legal Events

Date	Code	Title	Description
2007-03-08	NE	Application for restoration - patent lapsed through non-payment of renewal fees (section 60, patents law, 5727-1967)
2013-04-30	MM9K	Patent not in force due to non-payment of renewal fees

Publication	Publication Date	Title
IL135232A (en)	2005-05-17	21-hydroxy-6 19-oxidoprogesterone for treating excess of glucocorticoids
EP0874828A4 (fr)	1999-09-01	Compositions de traitement de la douleur
IL131484A0 (en)	2001-01-28	Treatment of cardiomyopathy
AP9600840A0 (en)	1996-07-31	Treatment of ovarian estrogen dependent conditions
AU7582398A (en)	1998-12-11	Composition for treating skin conditions
PL338082A1 (en)	2000-09-25	Methods of treating obesity
GB9715295D0 (en)	1997-09-24	Novel method of treatment
GB9712866D0 (en)	1997-08-20	Novel method of treatment
GB9707693D0 (en)	1997-06-04	Novel method of treatment
GB9725114D0 (en)	1998-01-28	Treatment of pruritus
GB9715298D0 (en)	1997-09-24	Novel method of treatment
GB9715306D0 (en)	1997-09-24	Novel method of treatment
IL124419A0 (en)	1998-12-06	Composition for treating pain
PL341667A1 (en)	2001-04-23	Method of treating cooped
PL334803A1 (en)	2000-03-13	Derivatives of imino-aza-antracyclinone for treating amyloidosis
EP1007041A4 (fr)	2001-03-07	Composition analgesique
PL340430A1 (en)	2001-02-12	Combination for treating aids
AU7247898A (en)	1998-11-11	Composition for treating pain
PL335904A1 (en)	2000-05-22	Application of 7alpha-methyl-17alpha-ethynylestrane derivative for treating arteriosclerosis
EP0912178A4 (fr)	2000-08-16	Methodes de traitement de l'hypertension
IL120254A0 (en)	1997-06-10	Composition for treatment of acne
PL327430A1 (en)	1999-01-18	Set of shaped components
PL313849A1 (en)	1997-10-27	Beta-aminoesters of o-hydrobenzylamides
TW359161U (en)	1999-05-21	Apparatus for safeguarding women against incontinenece of urine
GB9705301D0 (en)	1997-04-30	Method of switching