IL135345A0 - Human toll homologues - Google Patents
Human toll homologuesInfo
- Publication number
- IL135345A0 IL135345A0 IL13534598A IL13534598A IL135345A0 IL 135345 A0 IL135345 A0 IL 135345A0 IL 13534598 A IL13534598 A IL 13534598A IL 13534598 A IL13534598 A IL 13534598A IL 135345 A0 IL135345 A0 IL 135345A0
- Authority
- IL
- Israel
- Prior art keywords
- human toll
- pro286
- pro285
- pro358
- proteins
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6225097P | 1997-10-17 | 1997-10-17 | |
| US6531197P | 1997-11-13 | 1997-11-13 | |
| US8332298P | 1998-04-28 | 1998-04-28 | |
| US9086398P | 1998-06-26 | 1998-06-26 | |
| US10541398A | 1998-06-26 | 1998-06-26 | |
| PCT/US1998/021141 WO1999020756A2 (fr) | 1997-10-17 | 1998-10-07 | Homologues toll humains |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL135345A0 true IL135345A0 (en) | 2001-05-20 |
Family
ID=27535565
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13534598A IL135345A0 (en) | 1997-10-17 | 1998-10-07 | Human toll homologues |
| IL135345A IL135345A (en) | 1997-10-17 | 2000-03-29 | Human toll homologues |
| IL180967A IL180967A (en) | 1997-10-17 | 2007-01-25 | Nucleic acid molecule encoding a toll like receptor homologue and a chimeric molecule comprising same |
| IL221367A IL221367A (en) | 1997-10-17 | 2012-08-09 | Isolated nucleic acid encoding a toll-like homologous protein and a toll-like homologous protein preparation process |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL135345A IL135345A (en) | 1997-10-17 | 2000-03-29 | Human toll homologues |
| IL180967A IL180967A (en) | 1997-10-17 | 2007-01-25 | Nucleic acid molecule encoding a toll like receptor homologue and a chimeric molecule comprising same |
| IL221367A IL221367A (en) | 1997-10-17 | 2012-08-09 | Isolated nucleic acid encoding a toll-like homologous protein and a toll-like homologous protein preparation process |
Country Status (11)
| Country | Link |
|---|---|
| EP (3) | EP1650219B1 (fr) |
| JP (3) | JP4319348B2 (fr) |
| AT (3) | ATE314471T1 (fr) |
| AU (1) | AU1070399A (fr) |
| CA (1) | CA2305385C (fr) |
| DE (3) | DE69841607D1 (fr) |
| DK (3) | DK1887014T3 (fr) |
| ES (2) | ES2343210T3 (fr) |
| IL (4) | IL135345A0 (fr) |
| PT (2) | PT1650219E (fr) |
| WO (1) | WO1999020756A2 (fr) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7696327B1 (en) | 1997-10-17 | 2010-04-13 | Genentech, Inc. | Antibodies to human Toll homologues |
| AU2001264889B2 (en) * | 1997-05-07 | 2006-06-29 | Schering Corporation | Human receptor proteins; related reagents and methods |
| NZ338073A (en) * | 1997-05-07 | 2001-09-28 | Schering Corp | Eight related human, Toll receptor-like molecular structures: DTLR2, DTLR3, DTLR 5, DTLR6, DTLR 7, DTLR8, DTLR9 and DTLR10 and their biological activities |
| US20030032090A1 (en) | 1997-05-07 | 2003-02-13 | Schering Corporation, A New Jersey Corporation | Human receptor proteins; related reagents and methods |
| US6303321B1 (en) | 1999-02-11 | 2001-10-16 | North Shore-Long Island Jewish Research Institute | Methods for diagnosing sepsis |
| HUP0302240A2 (hu) * | 2000-05-25 | 2003-10-28 | Schering Corp. | Humán receptorfehérjék, ezekkel kapcsolatos reagensek és eljárások |
| JP2005500806A (ja) | 2000-09-15 | 2005-01-13 | コーリー ファーマシューティカル ゲーエムベーハー | CpGに基づく免疫アゴニスト/免疫アンタゴニストの高スループットスクリーニングのためのプロセス |
| US7304034B2 (en) | 2001-05-15 | 2007-12-04 | The Feinstein Institute For Medical Research | Use of HMGB fragments as anti-inflammatory agents |
| US7220723B2 (en) | 2001-05-15 | 2007-05-22 | The Feinstein Institute For Medical Research | Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents |
| EP1293566A1 (fr) * | 2001-09-17 | 2003-03-19 | Societe Des Produits Nestle S.A. | Un récepteur soluble de type toll |
| EP1495756A4 (fr) * | 2002-04-08 | 2009-10-28 | Takeda Pharmaceutical | Agent therapeutique pour la prevention d'etat septique grave |
| EP1575548B1 (fr) | 2002-05-04 | 2011-03-09 | Acorda Therapeutics, Inc. | Compositions et methodes visant a favoriser l'excroissance neuronale |
| MXPA05005071A (es) | 2002-11-12 | 2005-07-22 | Becton Dickinson Co | Diagnostico de la sepsis o sirs usando perfiles de biomarcadores. |
| WO2004047612A2 (fr) * | 2002-11-22 | 2004-06-10 | Nuvelo, Inc. | Procédés de thérapie et de diagnostic |
| WO2004094671A2 (fr) * | 2003-04-22 | 2004-11-04 | Coley Pharmaceutical Gmbh | Procedes et produits pour identifier et evaluer des ligands des tlr |
| US7959914B2 (en) | 2003-05-16 | 2011-06-14 | Acorda Therapeutics, Inc. | Methods of reducing extravasation of inflammatory cells |
| US7429375B2 (en) | 2003-05-16 | 2008-09-30 | Acorda Therapeutics, Inc. | Proteoglycan degrading mutants for the treatment of CNS |
| US7696169B2 (en) | 2003-06-06 | 2010-04-13 | The Feinstein Institute For Medical Research | Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents |
| JP4562123B2 (ja) * | 2003-06-17 | 2010-10-13 | 明治乳業株式会社 | Toll様レセプター強制発現細胞の利用 |
| WO2005001116A1 (fr) * | 2003-06-17 | 2005-01-06 | Meiji Dairies Corporation | Utilisation du recepteur de type toll exprimant de force des cellules |
| EP1668035A2 (fr) | 2003-09-11 | 2006-06-14 | Critical Therapeutics, Inc. | Anticorps monoclonaux diriges contre hmgb1 |
| ES2411504T3 (es) | 2004-05-18 | 2013-07-05 | Acorda Therapeutics, Inc. | Métodos de purificación de condroitinasa y formulaciones estables de la misma |
| DK1773872T3 (en) * | 2004-05-21 | 2017-05-08 | Uab Res Found | VARIABLE Lymphocyte Receptors, Associated Polypeptides and Nucleic Acids, and Uses thereof |
| KR20080006617A (ko) | 2005-04-15 | 2008-01-16 | 백톤 디킨슨 앤드 컴퍼니 | 패혈증의 진단 |
| WO2007038548A2 (fr) | 2005-09-26 | 2007-04-05 | Acorda Therapeutics, Inc. | Compositions et procedes d'utilisation de mutants des chondroitinases abci |
| JP5199878B2 (ja) | 2005-10-27 | 2013-05-15 | セントカー・インコーポレーテツド | Toll様受容体3モジュレーター、方法および用途 |
| EP2082645A1 (fr) * | 2006-04-19 | 2009-07-29 | Genentech, Inc. | Nouvelle dislocation de gènes, compositions et procédés correspondants |
| EP2450442B1 (fr) | 2006-10-10 | 2017-07-19 | Acorda Therapeutics, Inc. | Compositions et procédés d'utilisation de mutants des chondroïtinase abci |
| US8669113B2 (en) | 2008-04-03 | 2014-03-11 | Becton, Dickinson And Company | Advanced detection of sepsis |
| NZ601635A (en) | 2010-01-27 | 2013-06-28 | Takeda Pharmaceutical | Compounds for suppressing a peripheral nerve disorder induced by an anti-cancer agent |
| CN117534753B (zh) * | 2023-12-07 | 2024-05-10 | 北京博奥森生物技术有限公司 | 一种诱导高性能NF-κB多克隆抗体多肽及其应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4676980A (en) | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
| DE3850542T2 (de) | 1987-09-23 | 1994-11-24 | Bristol Myers Squibb Co | Antikörper-Heterokonjugate zur Töting von HIV-infizierten Zellen. |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| EP0479909B1 (fr) | 1989-06-29 | 1996-10-30 | Medarex, Inc. | Reactifs bispecifiques pour le traitement du sida |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| AU8507191A (en) | 1990-08-29 | 1992-03-30 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| WO1992020373A1 (fr) | 1991-05-14 | 1992-11-26 | Repligen Corporation | Anticorps d'heteroconjugues pour le traitement des infections a l'hiv |
| WO1993008829A1 (fr) | 1991-11-04 | 1993-05-13 | The Regents Of The University Of California | Compositions induisant la destruction de cellules infectees par l'hiv |
| NZ338073A (en) * | 1997-05-07 | 2001-09-28 | Schering Corp | Eight related human, Toll receptor-like molecular structures: DTLR2, DTLR3, DTLR 5, DTLR6, DTLR 7, DTLR8, DTLR9 and DTLR10 and their biological activities |
| DK1386931T3 (da) * | 1998-03-25 | 2006-09-04 | Genentech Inc | Human neurotriminhomolog |
-
1998
- 1998-10-07 EP EP05023238A patent/EP1650219B1/fr not_active Expired - Lifetime
- 1998-10-07 ES ES07020354T patent/ES2343210T3/es not_active Expired - Lifetime
- 1998-10-07 AT AT98953294T patent/ATE314471T1/de not_active IP Right Cessation
- 1998-10-07 CA CA2305385A patent/CA2305385C/fr not_active Expired - Lifetime
- 1998-10-07 AU AU10703/99A patent/AU1070399A/en not_active Abandoned
- 1998-10-07 DE DE69841607T patent/DE69841607D1/de not_active Expired - Lifetime
- 1998-10-07 DE DE69838888T patent/DE69838888T2/de not_active Expired - Lifetime
- 1998-10-07 DK DK07020354.2T patent/DK1887014T3/da active
- 1998-10-07 PT PT05023238T patent/PT1650219E/pt unknown
- 1998-10-07 JP JP2000517077A patent/JP4319348B2/ja not_active Expired - Lifetime
- 1998-10-07 AT AT07020354T patent/ATE463502T1/de active
- 1998-10-07 EP EP07020354A patent/EP1887014B1/fr not_active Expired - Lifetime
- 1998-10-07 EP EP98953294A patent/EP1025227B1/fr not_active Revoked
- 1998-10-07 IL IL13534598A patent/IL135345A0/xx active IP Right Grant
- 1998-10-07 ES ES05023238T patent/ES2298905T3/es not_active Expired - Lifetime
- 1998-10-07 WO PCT/US1998/021141 patent/WO1999020756A2/fr not_active Ceased
- 1998-10-07 DK DK05023238T patent/DK1650219T3/da active
- 1998-10-07 AT AT05023238T patent/ATE381574T1/de active
- 1998-10-07 PT PT07020354T patent/PT1887014E/pt unknown
- 1998-10-07 DK DK98953294T patent/DK1025227T3/da active
- 1998-10-07 DE DE69833014T patent/DE69833014T2/de not_active Revoked
-
2000
- 2000-03-29 IL IL135345A patent/IL135345A/en not_active IP Right Cessation
-
2007
- 2007-01-25 IL IL180967A patent/IL180967A/en not_active IP Right Cessation
-
2008
- 2008-12-24 JP JP2008328570A patent/JP5027105B2/ja not_active Expired - Lifetime
-
2012
- 2012-01-31 JP JP2012017737A patent/JP5425244B2/ja not_active Expired - Lifetime
- 2012-08-09 IL IL221367A patent/IL221367A/en not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed |