IL138433A0 - Barbituric acid derivative and preventive and theraputic agent for bone and cartilage containing the same - Google Patents

Barbituric acid derivative and preventive and theraputic agent for bone and cartilage containing the same

Info

Publication number
IL138433A0
IL138433A0 IL13843399A IL13843399A IL138433A0 IL 138433 A0 IL138433 A0 IL 138433A0 IL 13843399 A IL13843399 A IL 13843399A IL 13843399 A IL13843399 A IL 13843399A IL 138433 A0 IL138433 A0 IL 138433A0
Authority
IL
Israel
Prior art keywords
preventive
bone
same
acid derivative
barbituric acid
Prior art date
Application number
IL13843399A
Other languages
English (en)
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of IL138433A0 publication Critical patent/IL138433A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A61K31/515—Barbituric acids; Derivatives thereof, e.g. sodium pentobarbital
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms
    • C07D239/62—Barbituric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL13843399A 1998-03-27 1999-03-23 Barbituric acid derivative and preventive and theraputic agent for bone and cartilage containing the same IL138433A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10100355A JPH11279157A (ja) 1998-03-27 1998-03-27 バルビツール酸誘導体およびそれらからなる骨・軟骨疾患予防・治療薬
PCT/IB1999/000961 WO1999050252A2 (en) 1998-03-27 1999-03-23 Barbituric acid derivative and preventive and therapeutic agent for bone and cartilage containing the same

Publications (1)

Publication Number Publication Date
IL138433A0 true IL138433A0 (en) 2001-10-31

Family

ID=14271794

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13843399A IL138433A0 (en) 1998-03-27 1999-03-23 Barbituric acid derivative and preventive and theraputic agent for bone and cartilage containing the same

Country Status (20)

Country Link
US (1) US6498164B1 (cs)
EP (1) EP1064269A1 (cs)
JP (1) JPH11279157A (cs)
KR (1) KR20010042182A (cs)
CN (1) CN1295565A (cs)
AU (1) AU759249B2 (cs)
BR (1) BR9909139A (cs)
CA (1) CA2324584A1 (cs)
CZ (1) CZ20003460A3 (cs)
EA (1) EA200000992A1 (cs)
HU (1) HUP0101505A3 (cs)
IL (1) IL138433A0 (cs)
NO (1) NO20004798L (cs)
NZ (1) NZ506616A (cs)
PL (1) PL343433A1 (cs)
SK (1) SK14032000A3 (cs)
TR (1) TR200002785T2 (cs)
WO (1) WO1999050252A2 (cs)
YU (1) YU57800A (cs)
ZA (1) ZA200004473B (cs)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0508052A (pt) * 2004-02-26 2007-07-17 Inotek Pharmaceuticals Corp derivados de lactamo tetracìclico e seus usos
CN102070623B (zh) * 2010-12-20 2012-07-25 新乡医学院 一种巴比妥酸衍生物及其制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2921072A (en) * 1956-10-18 1960-01-12 Jr Edgar A Ferguson Nicotinic acid substituents of barbituric acid
GB1339748A (en) * 1970-07-02 1973-12-05 Ici Ltd Pyrimidine derivatives
JPS5829281B2 (ja) * 1974-06-04 1983-06-22 日本曹達株式会社 バルビツ−ル酸系除草剤
US4695673A (en) * 1985-11-20 1987-09-22 Stauffer Chemical Company Process for the production of acylated 1,3-dicarbonyl compounds
US4797147A (en) * 1986-06-09 1989-01-10 Stauffer Chemical Company Herbicidal method and composition utilizing certain 5-(2-substituted benzoyl)-barbituric acids
US4938796A (en) * 1987-07-06 1990-07-03 Ici Americas Inc. Herbicidal compositions of acylated 1,3-dicarbonyl herbicides and antidotes therefor
JP2588780B2 (ja) * 1989-09-26 1997-03-12 富士写真フイルム株式会社 電子写真感光体
JP2588779B2 (ja) * 1989-09-18 1997-03-12 富士写真フイルム株式会社 電子写真式製版用印刷原版
US5102760A (en) * 1989-09-18 1992-04-07 Fuji Photo Film Co., Ltd. Electrophotographic photoreceptor and electrophotographic printing plate precursor comprising phthalocyanine pigment and thiobarbituric acid derivative
JPH03179361A (ja) * 1989-12-07 1991-08-05 Fuji Photo Film Co Ltd 光導電性組成物およびそれを用いた電子写真感光材料
US5141943A (en) * 1990-04-12 1992-08-25 Brown University Research Foundation 5-benzyl barbiturate derivatives
NL9001075A (cs) * 1990-05-04 1991-12-02 Duphar Int Res
DK0517660T3 (da) * 1991-06-05 1997-10-27 Ciba Geigy Ag Benzo-1,2,3-thiadiazol-derivater.
WO1996025402A1 (en) * 1995-02-13 1996-08-22 Gulliya Kirpal S Novel uses for barbituric acid analogs
JPH10316608A (ja) * 1997-05-14 1998-12-02 Hoechst Yakuhin Kogyo Kk ポリヒドロキシフェノール誘導体およびそれらからなる骨・軟骨疾患予防・治療剤

Also Published As

Publication number Publication date
KR20010042182A (ko) 2001-05-25
AU759249B2 (en) 2003-04-10
HUP0101505A3 (en) 2002-06-28
CN1295565A (zh) 2001-05-16
EA200000992A1 (ru) 2001-06-25
TR200002785T2 (tr) 2001-02-21
BR9909139A (pt) 2000-12-05
SK14032000A3 (sk) 2001-03-12
WO1999050252A3 (en) 2000-01-13
US6498164B1 (en) 2002-12-24
CA2324584A1 (en) 1999-10-07
NO20004798D0 (no) 2000-09-26
YU57800A (sh) 2002-10-18
EP1064269A1 (en) 2001-01-03
AU3726099A (en) 1999-10-18
PL343433A1 (en) 2001-08-13
NO20004798L (no) 2000-11-20
CZ20003460A3 (cs) 2001-08-15
JPH11279157A (ja) 1999-10-12
NZ506616A (en) 2003-04-29
WO1999050252A2 (en) 1999-10-07
ZA200004473B (en) 2001-05-30
HUP0101505A2 (hu) 2002-03-28

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