IL141933A0 - Process for the production of a naphthyridine carboxylic acid derivative (methanesulfonate sesquihydrate) - Google Patents

Process for the production of a naphthyridine carboxylic acid derivative (methanesulfonate sesquihydrate)

Info

Publication number
IL141933A0
IL141933A0 IL14193399A IL14193399A IL141933A0 IL 141933 A0 IL141933 A0 IL 141933A0 IL 14193399 A IL14193399 A IL 14193399A IL 14193399 A IL14193399 A IL 14193399A IL 141933 A0 IL141933 A0 IL 141933A0
Authority
IL
Israel
Prior art keywords
production
carboxylic acid
acid derivative
naphthyridine carboxylic
methanesulfonate sesquihydrate
Prior art date
Application number
IL14193399A
Other languages
English (en)
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of IL141933A0 publication Critical patent/IL141933A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
IL14193399A 1998-09-18 1999-09-15 Process for the production of a naphthyridine carboxylic acid derivative (methanesulfonate sesquihydrate) IL141933A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9820405.0A GB9820405D0 (en) 1998-09-18 1998-09-18 Process
PCT/EP1999/007003 WO2000017199A1 (en) 1998-09-18 1999-09-15 Process for the production of a naphthyridine carboxylic acid derivative (methanesulfonate sesquihydrate)

Publications (1)

Publication Number Publication Date
IL141933A0 true IL141933A0 (en) 2002-03-10

Family

ID=10839123

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14193399A IL141933A0 (en) 1998-09-18 1999-09-15 Process for the production of a naphthyridine carboxylic acid derivative (methanesulfonate sesquihydrate)
IL141933A IL141933A (en) 1998-09-18 2001-03-09 Process for the production of acid 7– (3 – aminomethyl) –4 – China – methoxyaminopyrrolidine – 1 – ile) –1 – cyclopropyl-6 – fluorine – 4,1 – dihydro-4 – oxo – 8,1 – naphthyridine – 3 – carboxylate methanesulfonate Scoohydrate

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL141933A IL141933A (en) 1998-09-18 2001-03-09 Process for the production of acid 7– (3 – aminomethyl) –4 – China – methoxyaminopyrrolidine – 1 – ile) –1 – cyclopropyl-6 – fluorine – 4,1 – dihydro-4 – oxo – 8,1 – naphthyridine – 3 – carboxylate methanesulfonate Scoohydrate

Country Status (24)

Country Link
US (1) US6818771B1 (cs)
EP (1) EP1114050B1 (cs)
JP (1) JP2002526498A (cs)
KR (1) KR100679062B1 (cs)
CN (1) CN1315825C (cs)
AT (1) ATE337315T1 (cs)
AU (1) AU751060B2 (cs)
BR (1) BR9913858A (cs)
CA (1) CA2344439C (cs)
CY (1) CY1106171T1 (cs)
CZ (1) CZ297509B6 (cs)
DE (1) DE69932938T8 (cs)
DK (1) DK1114050T3 (cs)
ES (1) ES2272084T3 (cs)
GB (1) GB9820405D0 (cs)
HU (1) HU227068B1 (cs)
IL (2) IL141933A0 (cs)
NO (1) NO317997B1 (cs)
NZ (1) NZ510590A (cs)
PL (1) PL194707B1 (cs)
PT (1) PT1114050E (cs)
TR (1) TR200100797T2 (cs)
WO (1) WO2000017199A1 (cs)
ZA (1) ZA200102160B (cs)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA24500A1 (fr) 1997-03-21 1998-10-01 Lg Life Sciences Ltd Derive du sel d'acide carboxylique de naphthyridine .
US20020032216A1 (en) 1997-03-21 2002-03-14 Lg Chemical Ltd. Salt of naphthyridine carboxylic acid derivative
CA2281817C (en) * 1999-06-29 2008-07-29 Smithkline Beecham Corporation Methods of use of fluoroquinolone compounds against maxillary sinus pathogenic bacteria
GB9920919D0 (en) 1999-09-03 1999-11-10 Sb Pharmco Inc Novel compound
GB9920917D0 (en) 1999-09-03 1999-11-10 Sb Pharmco Inc Novel process
KR20010091379A (ko) * 2000-03-15 2001-10-23 성재갑 7-(4-아미노메틸-3-옥심)피롤리딘 치환체를 갖는 퀴놀린카르복실산 유도체의 신규 제조방법
ES2314082T3 (es) 2001-08-02 2009-03-16 Lg Life Sciences Limited Procedimientos para la produccion de derivados amino protegidos de 4-aminometilenpirrolidin-3-ona, gemifloxacina y sus sales.
KR100517638B1 (ko) 2002-04-08 2005-09-28 주식회사 엘지생명과학 게미플록사신 산염의 새로운 제조방법
EP1844047A1 (en) * 2004-10-18 2007-10-17 Neurocrine Biosciences, Inc. Hydrate of n-methyl-n-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-alpha]- pyramidin-7-yl}phenyl)acetamide and processes and methods related thereto
US7834027B2 (en) * 2005-06-15 2010-11-16 Hetero Drugs Limited Gemifloxacin process and polymorphs

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57134482A (en) 1981-02-13 1982-08-19 Dainippon Pharmaceut Co Ltd 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8- naphthyridine-3-carboxylic acid-3/2 hydrate and its preparation
JPH0356479A (ja) 1989-07-24 1991-03-12 Takeshi Yokota 水溶性キノロン誘導体のｐ‐トルエンスルホン酸塩
PL166381B1 (pl) * 1989-08-16 1995-05-31 Pfizer Sposób wytwarzania nowych podstawionych kwasów 7-azabicyklochinolonokarboksylowych PL PL PL PL
DK0688772T3 (da) 1994-06-16 1999-11-01 Lg Chemical Ltd Quinolincarboxylsyrederivater med 7-(4-aminomethyl-3-oxim)-pyrrolidinsubstituenter og fremgangsmåde til deres fremstilling
US5776944A (en) 1994-06-16 1998-07-07 Lg Chemical Ltd. 7-(4-aminomethyl-3-methyloxyiminopyrroplidin-1-yl)-1-cyclopropyl-6-flu oro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid and the process for the preparation thereof
JP3449658B2 (ja) * 1994-12-21 2003-09-22 杏林製薬株式会社 安定性に優れた８−アルコキシキノロンカルボン酸水和物並びにその製造方法
DE69503066T2 (de) * 1995-06-06 1998-10-15 Pfizer Inc., New York, N.Y. KRISTALLFORM VON WASSERFREIEN 7-((1a,5a,6a)-6-AMINO-3-AZABICYCLO (3.1.0.) HEX-3-YL)-6-FLUORO-1-(2,4-DIFLUOROPHENYL)-1,4-DIHYDRO-4-OXO-1,8-NAPHTHYRIDIN-CARBONSÄURE METHANESULFONSÄURE SALZ
IL122649A (en) * 1995-08-11 2001-08-26 Pfizer (1s, 2s) - 1- (4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-propanol methanesulfonate trihydrate, its use in the preparation of medicaments and pharmaceutical compositions comprising same
UA49880C2 (uk) 1996-03-29 2002-10-15 Смітклайн Бічам Корпорейшн Дигідрат ерпоcартану, фармацевтична композиція, спосіб отримання твердої дозованої форми, спосіб блокування рецепторів ангіотензину іі
US20020032216A1 (en) 1997-03-21 2002-03-14 Lg Chemical Ltd. Salt of naphthyridine carboxylic acid derivative
MA24500A1 (fr) 1997-03-21 1998-10-01 Lg Life Sciences Ltd Derive du sel d'acide carboxylique de naphthyridine .
KR100286874B1 (ko) 1998-03-04 2001-04-16 성재갑 보호된 4-아미노메틸-피롤리딘-3-온의 제조방법
EP1082300B1 (en) 1998-05-29 2003-09-10 PHARMACIA & UPJOHN COMPANY 3-[(1'-n-methylamino)ethyl-n-benzyl]pyrrolidine monomethanesulfonate

Also Published As

Publication number Publication date
EP1114050B1 (en) 2006-08-23
DE69932938D1 (de) 2006-10-05
US6818771B1 (en) 2004-11-16
NO317997B1 (no) 2005-01-17
HU227068B1 (hu) 2010-06-28
PL346656A1 (en) 2002-02-25
NZ510590A (en) 2003-05-30
AU751060B2 (en) 2002-08-08
CA2344439C (en) 2010-05-11
EP1114050A1 (en) 2001-07-11
ZA200102160B (en) 2002-06-26
HUP0103914A2 (hu) 2002-03-28
NO20011290D0 (no) 2001-03-14
ATE337315T1 (de) 2006-09-15
NO20011290L (no) 2001-03-14
CN1315825C (zh) 2007-05-16
BR9913858A (pt) 2001-06-12
AU6328399A (en) 2000-04-10
TR200100797T2 (tr) 2001-10-22
CA2344439A1 (en) 2000-03-30
DE69932938T8 (de) 2007-07-12
GB9820405D0 (en) 1998-11-11
KR100679062B1 (ko) 2007-02-05
CZ297509B6 (cs) 2007-01-03
PL194707B1 (pl) 2007-06-29
HUP0103914A3 (en) 2002-05-28
KR20010075160A (ko) 2001-08-09
ES2272084T3 (es) 2007-04-16
DE69932938T2 (de) 2007-03-15
CN1318066A (zh) 2001-10-17
JP2002526498A (ja) 2002-08-20
CZ2001978A3 (cs) 2002-01-16
CY1106171T1 (el) 2011-06-08
PT1114050E (pt) 2006-12-29
DK1114050T3 (da) 2006-10-09
HK1038557A1 (en) 2002-03-22
IL141933A (en) 2009-02-11
WO2000017199A1 (en) 2000-03-30

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Legal Events

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FF Patent granted
KB Patent renewed