IL143156A - Therapeutic anti-fungal nail preparation - Google Patents

Therapeutic anti-fungal nail preparation

Info

Publication number: IL143156A
Authority: IL; Israel
Prior art keywords: dmso; solution; miconazole; ibuprofen; polyglycol
Prior art date: 1998-11-16

Application number

IL14315699A

Other languages

English (en)

Other versions

IL143156A0 (en

Original Assignee

Astan Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-11-16

Filing date

1999-11-15

Publication date

2005-11-20

1999-11-15 Application filed by Astan Inc filed Critical Astan Inc

2002-04-21 Publication of IL143156A0 publication Critical patent/IL143156A0/xx

2005-11-20 Publication of IL143156A publication Critical patent/IL143156A/xx

Links

230000001225 therapeutic effect Effects 0.000 title abstract 4
230000000843 anti-fungal effect Effects 0.000 title 1
IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 abstract 12
HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 abstract 3
BYBLEWFAAKGYCD-UHFFFAOYSA-N Miconazole Chemical compound ClC1=CC(Cl)=CC=C1COC(C=1C(=CC(Cl)=CC=1)Cl)CN1C=NC=C1 BYBLEWFAAKGYCD-UHFFFAOYSA-N 0.000 abstract 3
208000010195 Onychomycosis Diseases 0.000 abstract 3
229960001680 ibuprofen Drugs 0.000 abstract 3
229960002509 miconazole Drugs 0.000 abstract 3
229920000151 polyglycol Polymers 0.000 abstract 3
239000010695 polyglycol Substances 0.000 abstract 3
229940121375 antifungal agent Drugs 0.000 abstract 2
239000003429 antifungal agent Substances 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
201000005882 tinea unguium Diseases 0.000 abstract 2
230000003466 anti-cipated effect Effects 0.000 abstract 1
229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
239000002260 anti-inflammatory agent Substances 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
230000003190 augmentative effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
230000002538 fungal effect Effects 0.000 abstract 1
208000015181 infectious disease Diseases 0.000 abstract 1
239000004615 ingredient Substances 0.000 abstract 1
230000035515 penetration Effects 0.000 abstract 1
230000009885 systemic effect Effects 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Emergency Medicine (AREA)
Oil, Petroleum & Natural Gas (AREA)
Dermatology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Bioinformatics & Cheminformatics (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

IL14315699A 1998-11-16 1999-11-15 Therapeutic anti-fungal nail preparation IL143156A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US09/193,073 US6159977A (en)	1998-11-16	1998-11-16	Therapeutic anti-fungal nail preparation
PCT/US1999/027053 WO2000028821A1 (fr)	1998-11-16	1999-11-15	Preparation antifongique therapeutique pour ongles

Publications (2)

Publication Number	Publication Date
IL143156A0 IL143156A0 (en)	2002-04-21
IL143156A true IL143156A (en)	2005-11-20

Family

ID=22712177

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL14315699A IL143156A (en)	1998-11-16	1999-11-15	Therapeutic anti-fungal nail preparation

Country Status (12)

Country	Link
US (2)	US6159977A (fr)
EP (1)	EP1130964B1 (fr)
JP (1)	JP2003535020A (fr)
CN (1)	CN1181738C (fr)
AT (1)	ATE309032T1 (fr)
AU (1)	AU771851B2 (fr)
BR (1)	BR9915394A (fr)
CA (1)	CA2351536C (fr)
DE (1)	DE69928278T2 (fr)
IL (1)	IL143156A (fr)
MX (1)	MXPA01004908A (fr)
WO (1)	WO2000028821A1 (fr)

Families Citing this family (89)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6605751B1 (en)	1997-11-14	2003-08-12	Acrymed	Silver-containing compositions, devices and methods for making
US7655252B2 (en)	1999-04-28	2010-02-02	The Regents Of The University Of Michigan	Antimicrobial nanoemulsion compositions and methods
US6635676B2 (en) *	1999-04-28	2003-10-21	Regents Of The University Of Michigan	Non-toxic antimicrobial compositions and methods of use
US6541517B1 (en) *	1999-09-03	2003-04-01	Donald M. Murphy	Treatment of skin disorders
US8679523B2 (en)	1999-12-30	2014-03-25	Kimberly-Clark Worldwide, Inc.	Oxygen-delivery closed cell foam matrix for wound treatment
US8257688B2 (en) *	2000-03-27	2012-09-04	Taro Pharmaceuticals Industries	Controlled delivery system of antifungal and keratolytic agents for local treatment of fungal infections of the nail and surrounding tissues
US7074392B1 (en)	2000-03-27	2006-07-11	Taro Pharmaceutical Industries Limited	Controllled delivery system of antifungal and keratolytic agents for local treatment of fungal infections
US6878365B2 (en) *	2001-03-10	2005-04-12	James Edward Brehove	Topical application for treating toenail fungus
GB0108082D0 (en) *	2001-03-30	2001-05-23	Novartis Consumer Health Sa	Topical composition
JP2010209109A (ja) *	2001-06-25	2010-09-24	Regents Of The Univ Of Michigan	抗微生物ナノエマルジョンの組成物および方法
CA2468539C (fr) *	2001-10-22	2013-01-08	Michael A. Repka	Administration de medicaments a l'ongle
US20030144625A1 (en) *	2002-01-28	2003-07-31	Garry Sherman	Method and apparatus for the treatment of infections of the nail matrix and nail plate
US6921529B2 (en) *	2002-07-29	2005-07-26	Joseph C. Maley	Treatment modality and method for fungal nail infection
CN1678277B (zh)	2002-07-29	2010-05-05	艾克里麦德公司	治疗皮肤病的方法和组合物
US7374772B2 (en) *	2002-11-07	2008-05-20	Bommarito Alexander A	Topical antifungal treatment
US20040126343A1 (en) *	2002-12-26	2004-07-01	Garshowitz Solomon David	Nail drug delivery
US7311928B2 (en) *	2003-12-09	2007-12-25	Briant Burke	Topical compositions containing tea tree oil for treatment of viral lesions
EP1781098B1 (fr)	2004-07-30	2015-10-07	Avent, Inc.	Dispositifs antimicrobiens et compositions associees
US8361553B2 (en)	2004-07-30	2013-01-29	Kimberly-Clark Worldwide, Inc.	Methods and compositions for metal nanoparticle treated surfaces
CN101010003B (zh)	2004-07-30	2012-07-04	金佰利-克拉克国际公司	抗微生物的银组合物
US9289378B2 (en)	2004-09-20	2016-03-22	Avent, Inc.	Antimicrobial amorphous compositions
US7740875B2 (en) *	2004-10-08	2010-06-22	Mediquest Therapeutics, Inc.	Organo-gel formulations for therapeutic applications
US20060078580A1 (en) *	2004-10-08	2006-04-13	Mediquest Therapeutics, Inc.	Organo-gel formulations for therapeutic applications
US20060275230A1 (en)	2004-12-10	2006-12-07	Frank Kochinke	Compositions and methods for treating conditions of the nail unit
CN101115475A (zh) *	2004-12-10	2008-01-30	塔利马治疗公司	用于治疗指甲单位病症的组合物和方法
US20060251593A1 (en) *	2005-04-07	2006-11-09	Work By Docs, Inc.	Colored nail enamel treatment
JP2010279384A (ja) *	2005-08-31	2010-12-16	Pola Pharma Inc	抗真菌剤
WO2007098591A2 (fr) *	2006-03-02	2007-09-07	Nuvo Research Inc.	Formulation topique pour les ongles
US8293965B2 (en)	2006-04-28	2012-10-23	Kimberly-Clark Worldwide, Inc.	Antimicrobial site dressings
LT2018164T (lt)	2006-05-12	2017-07-10	Christian Noe	Vaistų derinių, apimančių priešgrybelinius agentus, naudojimas
WO2008137747A1 (fr)	2007-05-02	2008-11-13	The Regents Of The University Of Michigan	Compositions thérapeutiques à base de nanoémulsion et leurs procédés d'utilisation
EP2166837A4 (fr) *	2007-06-19	2011-12-21	Prugen Inc	Combinaison médicamenteuse utilisable pour le traitement de troubles cutanés
US20110082118A1 (en) *	2007-06-19	2011-04-07	Bhiku Patel	Onychomycosis Treatment Delivery System
US20110076261A1 (en) *	2007-06-19	2011-03-31	Bhiku Patel	Antifungal Drug Delivery System
US20090175810A1 (en)	2008-01-03	2009-07-09	Gareth Winckle	Compositions and methods for treating diseases of the nail
US9320921B2 (en) *	2008-12-22	2016-04-26	Karen C. Swenholt	Nail fungus treatment and composition
CA2743904A1 (fr)	2008-11-17	2010-05-20	The Regents Of The University Of Michigan	Compositions de vaccins contre le cancer et leurs methodes d'utilisation
US8193232B2 (en) *	2009-02-13	2012-06-05	Topica Pharmaceuticals, Inc.	Anti-fungal formulation
NL1036661C2 (en)	2009-03-04	2010-09-07	Serrix B V	Anti-fungal compounds & compositions.
GB0907553D0 (en)	2009-05-01	2009-06-10	Insense Ltd	Treatment of human or animal body surface infection
US20100292333A1 (en) *	2009-05-15	2010-11-18	bioCEPTA Corporation	Compositions suitable for the topical treatment of fungal infections of the skin and nails
PL2547323T3 (pl)	2010-03-17	2016-07-29	Novaliq Gmbh	Kompozycja farmaceutyczna do leczenia podwyższonego ciśnienia wewnątrzgałkowego
SI23311A (sl) *	2010-03-19	2011-09-30	Kemijski inĹˇtitut	Farmacevtska kombinacija acetilsalicilne kisline in protiglivne substance za uničevanje ali inhibicijo rasti in replikacije gliv
ES2369101B2 (es)	2010-05-07	2012-08-02	Universidade De Santiago De Compostela	Sistema farmacéutico acuoso para la administración de fármacos en las uñas.
EP2444063A1 (fr)	2010-10-20	2012-04-25	Novaliq GmbH	Compositions pharmaceutiques liquides pour l'administration de principes actifs
EP2462921A1 (fr)	2010-11-11	2012-06-13	Novaliq GmbH	Compositions pharmaceutiques liquides pour le traitement d'une maladie de la chambre postérieure de l'oeil
US20140079741A1 (en) *	2011-03-18	2014-03-20	Katholieke Universiteit Leuven Ku Leuven Research & Development	Inhibition and treatment of biofilms
WO2012154740A1 (fr) *	2011-05-11	2012-11-15	Pellexa Research, Llc	Compositions antifongiques pour le traitement de la peau et des ongles
DK2714010T3 (en)	2011-05-25	2017-06-12	Novaliq Gmbh	TOPICAL PHARMACEUTICAL COMPOSITION BASED ON SEMIFLUORED ALKANES
JP6023181B2 (ja)	2011-05-25	2016-11-09	ノバリックゲーエムベーハー	爪に投与するための医薬組成物
KR101989648B1 (ko)	2012-01-23	2019-06-14	노바리크 게엠베하	부분불소화 알칸에 기초한 안정화된 단백질 조성물
WO2013122637A1 (fr) *	2012-02-17	2013-08-22	Capriotti Joseph	Compositions antifongiques destinées au traitement de la peau et des ongles
CA2775393C (fr) *	2012-05-02	2014-04-29	Samy Saad	Formulations pharmaceutiques topiques non aqueuses
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JP7563877B2 (ja) *	2018-12-14	2024-10-08	ロート製薬株式会社	爪及び爪周り用医薬組成物
EP3923907B1 (fr)	2019-02-13	2024-09-25	Novaliq GmbH	Compositions et procédés pour le traitement de la néovascularisation oculaire
CN110537545A (zh) *	2019-09-12	2019-12-06	青岛农业大学	噻康唑在制备用于防治植物病原菌的杀菌剂中的应用
ES2976036B2 (es) *	2024-03-06	2025-08-05	Univ Madrid Complutense	Potenciación de la acumulación intraungueal de principios activos

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6048486B2 (ja) *	1976-01-01	1985-10-28	木場常義	抗リウマチ剤
GB2105990B (en) *	1981-08-27	1985-06-19	Nitto Electric Ind Co	Adhesive skin patches
US4608249A (en) *	1982-11-02	1986-08-26	Nitto Electric Industrial Co., Ltd.	Hydrophilic therapeutic material
CA1236029A (fr) *	1984-05-14	1988-05-03	Edmund Sandborn	Solutions pharmaceutiques contenant du dimethylsulfoxyde
DE3520098A1 (de) *	1985-06-05	1986-12-11	Bayer Ag, 5090 Leverkusen	Azolderivate enthaltende formulierungen sowie ihre verwendung zur atraumatischen nagelentfernung
EP0270316A3 (fr) *	1986-12-04	1989-12-06	Pfizer Inc.	Compositions topiques contenant des imidazoles 1-substitués et des agents non-steroides anti-inflammatoires pour le traitement de l'acné
JP2797401B2 (ja) *	1989-04-19	1998-09-17	日産化学工業株式会社	爪用抗真菌剤組成物
US4927641A (en) *	1989-05-23	1990-05-22	Knight Gerald L	Veterinary liniment and method
US5874479A (en) *	1991-03-01	1999-02-23	Warner-Lambert Company	Therapeutic permeation enhanced-wound healing compositions and methods for preparing and using same
FR2673537B1 (fr) *	1991-03-08	1993-06-11	Oreal	Utilisation d'agents de penetration hydrophiles dans les compositions dermatologiques pour le traitement des onychomycoses, et compositions correspondantes.
JP3259972B2 (ja) *	1991-11-29	2002-02-25	ゼリア新薬工業株式会社	トルナフタート含有抗真菌剤
WO1993011734A1 (fr) *	1991-12-12	1993-06-24	Lts Lohmann Therapie-Systeme Gmbh & Co. Kg	Stratifie autoadhesif pour ongles des doigts et des orteils
WO1993021899A1 (fr) *	1992-05-05	1993-11-11	The Procter & Gamble Company	Composition de traitement de l'acne
GB2275191B (en) *	1993-02-10	1996-11-27	Donald John Dear	Use of antifungal compounds in the treatment of skin disorders
IL105600A (en) *	1993-05-04	1999-12-31	Allon Blank	Pharmaceutical and cosmetic compositions with increased rate of transdermal penetration and antioxidation protection against degradation containing derivatives of thioglycolic and mercaptopropionic acids some such novel compounds and their use
DE4337945A1 (de) *	1993-11-06	1995-05-11	Labtec Gmbh	Pflaster zur Behandlung von Nagelmykosen
IT1265001B1 (it) *	1993-12-16	1996-10-17	Zambon Spa	Composizione farmaceutica per uso topico contenente acido (s)-2-(4- isobutilfenil) propionico

1998
- 1998-11-16 US US09/193,073 patent/US6159977A/en not_active Expired - Lifetime
1999
- 1999-11-15 AT AT99960362T patent/ATE309032T1/de not_active IP Right Cessation
- 1999-11-15 DE DE69928278T patent/DE69928278T2/de not_active Expired - Lifetime
- 1999-11-15 MX MXPA01004908A patent/MXPA01004908A/es not_active IP Right Cessation
- 1999-11-15 CA CA002351536A patent/CA2351536C/fr not_active Expired - Fee Related
- 1999-11-15 CN CNB998147346A patent/CN1181738C/zh not_active Expired - Fee Related
- 1999-11-15 JP JP2000581886A patent/JP2003535020A/ja active Pending
- 1999-11-15 BR BR9915394-7A patent/BR9915394A/pt not_active Application Discontinuation
- 1999-11-15 EP EP99960362A patent/EP1130964B1/fr not_active Expired - Lifetime
- 1999-11-15 IL IL14315699A patent/IL143156A/xx not_active IP Right Cessation
- 1999-11-15 AU AU17257/00A patent/AU771851B2/en not_active Ceased
- 1999-11-15 WO PCT/US1999/027053 patent/WO2000028821A1/fr not_active Ceased
2000
- 2000-08-17 US US09/640,439 patent/US6391879B1/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
WO2000028821A1 (fr)	2000-05-25
AU1725700A (en)	2000-06-05
CN1359262A (zh)	2002-07-17
BR9915394A (pt)	2002-03-05
EP1130964A4 (fr)	2002-06-19
US6391879B1 (en)	2002-05-21
ATE309032T1 (de)	2005-11-15
US6159977A (en)	2000-12-12
EP1130964A1 (fr)	2001-09-12
CN1181738C (zh)	2004-12-29
IL143156A0 (en)	2002-04-21
AU771851B2 (en)	2004-04-01
DE69928278D1 (de)	2005-12-15
MXPA01004908A (es)	2003-03-10
EP1130964B1 (fr)	2005-11-09
CA2351536A1 (fr)	2000-05-25
CA2351536C (fr)	2007-08-07
DE69928278T2 (de)	2006-06-14
JP2003535020A (ja)	2003-11-25

Legal Events

Date	Code	Title
2006-02-21	FF	Patent granted
2010-05-17	KB	Patent renewed
2014-06-30	MM9K	Patent not in force due to non-payment of renewal fees

Publication	Publication Date	Title
IL143156A (en)	2005-11-20	Therapeutic anti-fungal nail preparation
EP1401421B1 (fr)	2010-03-03	Methodes et compositions pour le traitement de l'onychomycose et autres pathologies microbiennes et mycosiques
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ES2157307T3 (es)	2001-08-16	Composicion topica que contiene un antagonista de sustancia p.
MXPA04000654A (es)	2004-03-19	Terapia dermica usando derivados de fosfato de agente de transferencia de electrones.
SE9703191D0 (sv)	1997-09-04	Medicament for improvement of duration of muscle function or treatment of muscle disorders or diseases
AU1079701A (en)	2001-05-08	Oral transmucosal drug dosage using solid solution
CA2260185A1 (fr)	1999-04-17	Preparations de medicaments pour l'hormonotherapie substitutive a application topique sur la peau
GR77254B (fr)	1984-09-11
MXPA02002249A (es)	2004-07-30	Composiciones farmaceuticas agradables al paladar para animales de compania.
UA50719C2 (uk)	2002-11-15	Проліки для терапії пухлин і запальних захворювань
KR950003919B1 (ko)	1995-04-20	국소용 메트로니다졸 제제의 제조방법
WO2005007072A3 (fr)	2005-05-12	Methodes et compositions pharmaceutiques pour cicatriser des lesions
DE60115631D1 (de)	2006-01-12	Halbfester verabreichungsträger und arzneimittel
US20180036227A1 (en)	2018-02-08	Topical compositions
DE69935526D1 (de)	2007-04-26	Supramolekulare komplexe enthaltende arzneimittel
ES2137125A1 (es)	1999-12-01	La utilizacion de la sal de zinc del acido glicirretico en preparados contra el acne y las composiciones que contienen dicha sal.
IE810489L (en)	1981-09-06	Composition for topical application
EE9800208A (et)	1998-12-15	Vahend diabeedi komplikatsioonide profülaktikaks ja raviks
GR900100489A (el)	1991-11-15	Συνθέσεις χρήσιμοι ως αντισυλληπτικά για άνδρες.
WO2002055022A3 (fr)	2003-02-27	Metabolite actif de compose antifongique
WO2001007029A3 (fr)	2001-08-23	Guanidines substitutees et utilisation correspondante
EP0717994A1 (fr)	1996-06-26	Nouvelle formulation pour le traitement local du psoriasis
MX9301537A (es)	1994-01-31	Composicion de resina de intercambio de iones.
CA2486704A1 (fr)	2003-12-04	Preparation anticancereuse