IL143670A0 - Methods for the expression of active protein-immunoglobulin fusions, active protein-immunoglobulin fusions obtained thereby and pharmaceutical compositions containing the same - Google Patents

Methods for the expression of active protein-immunoglobulin fusions, active protein-immunoglobulin fusions obtained thereby and pharmaceutical compositions containing the same

Info

Publication number
IL143670A0
IL143670A0 IL14367099A IL14367099A IL143670A0 IL 143670 A0 IL143670 A0 IL 143670A0 IL 14367099 A IL14367099 A IL 14367099A IL 14367099 A IL14367099 A IL 14367099A IL 143670 A0 IL143670 A0 IL 143670A0
Authority
IL
Israel
Prior art keywords
active protein
immunoglobulin fusions
methods
expression
pharmaceutical compositions
Prior art date
Application number
IL14367099A
Other languages
English (en)
Original Assignee
Biogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22345666&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL143670(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biogen Inc filed Critical Biogen Inc
Publication of IL143670A0 publication Critical patent/IL143670A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
IL14367099A 1998-12-17 1999-12-16 Methods for the expression of active protein-immunoglobulin fusions, active protein-immunoglobulin fusions obtained thereby and pharmaceutical compositions containing the same IL143670A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11275298P 1998-12-17 1998-12-17
PCT/US1999/029873 WO2000036092A2 (en) 1998-12-17 1999-12-16 METHOD FOR THE HIGH LEVEL EXPRESSION OF ACTIVE LYMPHOTOXIN-β RECEPTOR IMMUNOGLOBULIN CHIMERIC PROTEINS AND THEIR PURIFICATION

Publications (1)

Publication Number Publication Date
IL143670A0 true IL143670A0 (en) 2002-04-21

Family

ID=22345666

Family Applications (3)

Application Number Title Priority Date Filing Date
IL14367099A IL143670A0 (en) 1998-12-17 1999-12-16 Methods for the expression of active protein-immunoglobulin fusions, active protein-immunoglobulin fusions obtained thereby and pharmaceutical compositions containing the same
IL205698A IL205698A (en) 1998-12-17 2010-05-11 Methods to Increase Fused Necrosis Factor Receptor (TNF) Factor Protein - IgFC and Reduce Factor Protein Fusion of TNF-IgFC Inactive Factor
IL229738A IL229738A0 (en) 1998-12-17 2013-12-01 Methods and preparations for increasing the expression of fusion proteins of a member of the tumor necrosis factor receptor (TNF)-ig fc family

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL205698A IL205698A (en) 1998-12-17 2010-05-11 Methods to Increase Fused Necrosis Factor Receptor (TNF) Factor Protein - IgFC and Reduce Factor Protein Fusion of TNF-IgFC Inactive Factor
IL229738A IL229738A0 (en) 1998-12-17 2013-12-01 Methods and preparations for increasing the expression of fusion proteins of a member of the tumor necrosis factor receptor (TNF)-ig fc family

Country Status (27)

Country Link
US (3) US7585946B2 (da)
EP (3) EP3006563A1 (da)
JP (4) JP4878676B2 (da)
KR (3) KR100732934B1 (da)
CN (2) CN101289512A (da)
AT (1) ATE536372T1 (da)
AU (2) AU777232B2 (da)
BR (1) BR9916325B1 (da)
CA (1) CA2354539A1 (da)
CY (1) CY1117003T1 (da)
CZ (1) CZ20012156A3 (da)
DK (2) DK2374872T4 (da)
EA (1) EA005270B1 (da)
EE (1) EE200100324A (da)
ES (1) ES2554482T5 (da)
HK (1) HK1223398A1 (da)
HU (1) HUP0200064A2 (da)
IL (3) IL143670A0 (da)
IS (1) IS5959A (da)
NO (1) NO20012991L (da)
NZ (3) NZ529276A (da)
PT (1) PT2374872E (da)
SG (1) SG123531A1 (da)
SI (1) SI2374872T2 (da)
SK (1) SK8552001A3 (da)
TR (2) TR200504220T2 (da)
WO (1) WO2000036092A2 (da)

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CA2511013A1 (en) * 2002-12-20 2004-07-15 Biogen Idec Ma Inc. Multivalent lymphotoxin beta receptor agonists and therapeutic uses thereof
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WO2005024012A1 (en) * 2003-09-11 2005-03-17 Novozymes A/S Increased expression of a modified polypeptide
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WO2007115230A2 (en) * 2006-03-30 2007-10-11 University Of Medicine And Dentistry Of New Jersey A strategy for homo- or hetero-dimerization of various proteins in solutions and in cells
UA94484C2 (uk) 2006-10-12 2011-05-10 Дженентек, Інк. Антитіла до лімфотоксину-альфа
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BRPI0908270A2 (pt) * 2008-02-29 2019-09-10 Biogen Idec Inc proteínas de fusão de imunoglobulinas purificadas e método para a sua purificação
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KR101454316B1 (ko) 2011-08-17 2014-10-27 한화케미칼 주식회사 활성형 ＴＮＦＲ-Ｆｃ 융합 단백질을 제조하는 방법
JP2015531244A (ja) 2012-10-15 2015-11-02 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ タンパク質を製造するための哺乳動物細胞培養方法
TW202423993A (zh) 2012-11-14 2024-06-16 美商再生元醫藥公司 重組細胞表面捕捉蛋白質
KR102669985B1 (ko) 2015-06-30 2024-05-29 샌포드 번햄 프레비즈 메디컬 디스커버리 인스티튜트 Btla 융합 단백질 작용제 및 이의 용도
KR101936049B1 (ko) 2015-10-15 2019-01-08 (주)알테오젠 IgG Fc 도메인을 가지는 융합 단백질의 생산방법
CN105400721A (zh) * 2015-12-11 2016-03-16 湖南农业大学 一种快速筛选具有抗菌活性芽孢杆菌的方法

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Also Published As

Publication number Publication date
CZ20012156A3 (cs) 2001-09-12
CN100387708C (zh) 2008-05-14
US20020039580A1 (en) 2002-04-04
EP2374872A2 (en) 2011-10-12
ES2554482T5 (es) 2019-07-18
NZ529276A (en) 2005-03-24
EP2374872B2 (en) 2019-02-20
JP2014239697A (ja) 2014-12-25
EE200100324A (et) 2002-10-15
PL348816A1 (en) 2002-06-17
PT2374872E (pt) 2015-12-09
JP2013116118A (ja) 2013-06-13
WO2000036092A9 (en) 2002-08-22
KR20020013482A (ko) 2002-02-20
IL205698A (en) 2015-11-30
NO20012991D0 (no) 2001-06-15
CN101289512A (zh) 2008-10-22
AU2005200042B2 (en) 2008-05-01
HK1038244A1 (en) 2002-03-08
TR200101703T2 (tr) 2002-05-21
ATE536372T1 (de) 2011-12-15
EP1141248B1 (en) 2011-12-07
US8709759B2 (en) 2014-04-29
WO2000036092A2 (en) 2000-06-22
NZ538599A (en) 2007-11-30
DK2374872T4 (da) 2019-04-23
AU2005200042A1 (en) 2005-02-03
NO20012991L (no) 2001-08-17
SI2374872T1 (sl) 2016-03-31
DK1141248T3 (da) 2012-03-12
US8283138B2 (en) 2012-10-09
US20130196376A1 (en) 2013-08-01
KR100732934B1 (ko) 2007-06-29
BR9916325A (pt) 2001-10-02
EP3006563A1 (en) 2016-04-13
US7585946B2 (en) 2009-09-08
IS5959A (is) 2001-05-31
JP2010158252A (ja) 2010-07-22
DK2374872T3 (da) 2015-12-14
EA005270B1 (ru) 2004-12-30
IL229738A0 (en) 2014-01-30
AU2364400A (en) 2000-07-03
KR20070091227A (ko) 2007-09-07
JP2003517277A (ja) 2003-05-27
HUP0200064A2 (en) 2002-05-29
CN1333819A (zh) 2002-01-30
SI2374872T2 (sl) 2019-05-31
JP5777171B2 (ja) 2015-09-09
KR20060084860A (ko) 2006-07-25
SG123531A1 (en) 2006-07-26
WO2000036092A3 (en) 2000-11-23
EA200100670A1 (ru) 2001-12-24
SK8552001A3 (en) 2001-12-03
AU777232B2 (en) 2004-10-07
ES2554482T3 (es) 2015-12-21
JP4878676B2 (ja) 2012-02-15
EP2374872A3 (en) 2011-10-19
US20100136625A1 (en) 2010-06-03
HK1223398A1 (en) 2017-07-28
EP1141248A2 (en) 2001-10-10
CY1117003T1 (el) 2017-04-05
EP2374872B1 (en) 2015-11-25
CA2354539A1 (en) 2000-06-22
BR9916325B1 (pt) 2011-06-28
NZ549623A (en) 2008-05-30
TR200504220T2 (tr) 2007-04-24

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