IL150488A0 - Use of pyrimidine endothelin antagonists in companion animals - Google Patents

Use of pyrimidine endothelin antagonists in companion animals

Info

Publication number: IL150488A0
Authority: IL; Israel
Prior art keywords: companion animals; pyrimidine; endothelin antagonists; endothelin; antagonists
Prior art date: 2000-02-11

Application number

IL15048801A

Other languages

English (en)

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-02-11

Filing date

2001-02-06

Publication date

2002-12-01

2001-02-06 Application filed by Pfizer filed Critical Pfizer

2002-12-01 Publication of IL150488A0 publication Critical patent/IL150488A0/xx

Links

102000002045 Endothelin Human genes 0.000 title abstract 2
108050009340 Endothelin Proteins 0.000 title abstract 2
241001465754 Metazoa Species 0.000 title abstract 2
ZUBDGKVDJUIMQQ-UBFCDGJISA-N endothelin-1 Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(O)=O)NC(=O)[C@H]1NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@@H](CC=2C=CC(O)=CC=2)NC(=O)[C@H](C(C)C)NC(=O)[C@H]2CSSC[C@@H](C(N[C@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N2)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](N)CSSC1)C1=CNC=N1 ZUBDGKVDJUIMQQ-UBFCDGJISA-N 0.000 title abstract 2
CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 title 1
239000005557 antagonist Substances 0.000 title 1
241000282472 Canis lupus familiaris Species 0.000 abstract 1
241000283086 Equidae Species 0.000 abstract 1
241000282326 Felis catus Species 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000001404 mediated effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Epidemiology (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Chemical Treatment Of Metals (AREA)

IL15048801A 2000-02-11 2001-02-06 Use of pyrimidine endothelin antagonists in companion animals IL150488A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0003234.2A GB0003234D0 (en)	2000-02-11	2000-02-11	Method of treatment
PCT/IB2001/000142 WO2001058882A1 (en)	2000-02-11	2001-02-06	Use of pyrimidine endothelin antagonists in companion animals

Publications (1)

Publication Number	Publication Date
IL150488A0 true IL150488A0 (en)	2002-12-01

Family

ID=9885465

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL15048801A IL150488A0 (en)	2000-02-11	2001-02-06	Use of pyrimidine endothelin antagonists in companion animals

Country Status (17)

Country	Link
EP (1)	EP1254120B1 (de)
JP (1)	JP2003528050A (de)
KR (1)	KR20020075791A (de)
AT (1)	ATE271042T1 (de)
AU (1)	AU3043601A (de)
CA (1)	CA2398007A1 (de)
DE (1)	DE60104283T2 (de)
DK (1)	DK1254120T3 (de)
ES (1)	ES2222975T3 (de)
GB (1)	GB0003234D0 (de)
HU (1)	HUP0204370A3 (de)
IL (1)	IL150488A0 (de)
NZ (1)	NZ519002A (de)
PT (1)	PT1254120E (de)
TR (1)	TR200401815T4 (de)
WO (1)	WO2001058882A1 (de)
ZA (1)	ZA200206343B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8647660B2 (en)	2004-12-29	2014-02-11	Hill's Pet Nutrition, Inc.	Combination of limited nutrients and enhanced dietary antioxidants to impart improved kidney health
AU2006236345B2 (en) *	2005-04-19	2011-03-31	Hill's Pet Nutrition, Inc.	Methods and compositions for the prevention and treatment of kidney disease
US8778617B2 (en) *	2010-02-25	2014-07-15	Hoffmann-La Roche Inc.	Method for determining the binding constant of high affinity compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP3087968B2 (ja) *	1995-12-20	2000-09-18	山之内製薬株式会社	アリールエテンスルホンアミド誘導体及びその医薬組成物
WO1998057938A1 (en) *	1997-06-19	1998-12-23	Yamanouchi Pharmaceutical Co., Ltd.	Substituted lower alkanesulfonamide derivatives and pharmaceutical composition containing the same

2000
- 2000-02-11 GB GBGB0003234.2A patent/GB0003234D0/en not_active Ceased
2001
- 2001-02-06 WO PCT/IB2001/000142 patent/WO2001058882A1/en not_active Ceased
- 2001-02-06 AU AU30436/01A patent/AU3043601A/en not_active Abandoned
- 2001-02-06 HU HU0204370A patent/HUP0204370A3/hu unknown
- 2001-02-06 DE DE2001604283 patent/DE60104283T2/de not_active Expired - Fee Related
- 2001-02-06 PT PT01902578T patent/PT1254120E/pt unknown
- 2001-02-06 CA CA002398007A patent/CA2398007A1/en not_active Abandoned
- 2001-02-06 JP JP2001558433A patent/JP2003528050A/ja not_active Withdrawn
- 2001-02-06 KR KR1020027010354A patent/KR20020075791A/ko not_active Ceased
- 2001-02-06 NZ NZ519002A patent/NZ519002A/en unknown
- 2001-02-06 DK DK01902578T patent/DK1254120T3/da active
- 2001-02-06 AT AT01902578T patent/ATE271042T1/de not_active IP Right Cessation
- 2001-02-06 IL IL15048801A patent/IL150488A0/xx unknown
- 2001-02-06 TR TR2004/01815T patent/TR200401815T4/xx unknown
- 2001-02-06 ES ES01902578T patent/ES2222975T3/es not_active Expired - Lifetime
- 2001-02-06 EP EP01902578A patent/EP1254120B1/de not_active Expired - Lifetime
2002
- 2002-08-08 ZA ZA200206343A patent/ZA200206343B/xx unknown

Also Published As

Publication number	Publication date
EP1254120B1 (de)	2004-07-14
HUP0204370A2 (en)	2003-05-28
GB0003234D0 (en)	2000-04-05
DE60104283T2 (de)	2004-11-18
AU3043601A (en)	2001-08-20
KR20020075791A (ko)	2002-10-05
ZA200206343B (en)	2003-08-08
HUP0204370A3 (en)	2003-07-28
ATE271042T1 (de)	2004-07-15
ES2222975T3 (es)	2005-02-16
CA2398007A1 (en)	2001-08-16
TR200401815T4 (tr)	2004-08-23
JP2003528050A (ja)	2003-09-24
EP1254120A1 (de)	2002-11-06
DK1254120T3 (da)	2004-10-04
DE60104283D1 (de)	2004-08-19
WO2001058882A1 (en)	2001-08-16
PT1254120E (pt)	2004-10-29
NZ519002A (en)	2004-06-25

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