IL150897A0 - Process for the preparation of acetyl-amidiniophenylalanyl cyclohexylglycyl-pyridinioalaninamides - Google Patents

Process for the preparation of acetyl-amidiniophenylalanyl cyclohexylglycyl-pyridinioalaninamides

Info

Publication number: IL150897A0
Authority: IL; Israel
Prior art keywords: pyridinioalaninamides; amidiniophenylalanyl; cyclohexylglycyl; acetyl; preparation
Prior art date: 2000-01-28

Application number

IL15089701A

Other languages

English (en)

Original Assignee

Aventis Pharma Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-01-28

Filing date

2001-01-18

Publication date

2003-02-12

2001-01-18 Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh

2003-02-12 Publication of IL150897A0 publication Critical patent/IL150897A0/xx

Links

-1 cyclohexylglycyl-pyridinioalaninamides Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Diabetes (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Hematology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Peptides Or Proteins (AREA)
Pyridine Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Catalysts (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Investigating Or Analysing Biological Materials (AREA)

IL15089701A 2000-01-28 2001-01-18 Process for the preparation of acetyl-amidiniophenylalanyl cyclohexylglycyl-pyridinioalaninamides IL150897A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10003586		2000-01-28
PCT/EP2001/000523 WO2001055175A2 (en)	2000-01-28	2001-01-18	Process for the preparation of acetyl-amidiniophenylalanyl-cyclohexylglycyl-pyridinioalaninamides

Publications (1)

Publication Number	Publication Date
IL150897A0 true IL150897A0 (en)	2003-02-12

Family

ID=7628946

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL15089701A IL150897A0 (en)	2000-01-28	2001-01-18	Process for the preparation of acetyl-amidiniophenylalanyl cyclohexylglycyl-pyridinioalaninamides
IL150897A IL150897A (en)	2000-01-28	2002-07-24	Process for the preparation of acetyl-amidiniophenylalanyl-cyclohexylglycyl-pyridylalanine

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL150897A IL150897A (en)	2000-01-28	2002-07-24	Process for the preparation of acetyl-amidiniophenylalanyl-cyclohexylglycyl-pyridylalanine

Country Status (29)

Country	Link
US (2)	US20010031858A1 (cs)
EP (1)	EP1254159B9 (cs)
JP (1)	JP4778181B2 (cs)
KR (1)	KR100758141B1 (cs)
CN (1)	CN1176104C (cs)
AR (1)	AR027246A1 (cs)
AT (1)	ATE325810T1 (cs)
AU (1)	AU779722B2 (cs)
BR (1)	BR0107804A (cs)
CA (1)	CA2398497C (cs)
CZ (1)	CZ20022583A3 (cs)
DE (1)	DE60119491T2 (cs)
DK (1)	DK1254159T3 (cs)
EE (1)	EE200200410A (cs)
ES (1)	ES2262632T3 (cs)
HR (1)	HRP20020631A2 (cs)
HU (1)	HUP0301986A2 (cs)
IL (2)	IL150897A0 (cs)
MX (1)	MXPA02006762A (cs)
NO (1)	NO20023577L (cs)
NZ (1)	NZ520427A (cs)
PL (1)	PL356801A1 (cs)
PT (1)	PT1254159E (cs)
RU (1)	RU2250212C2 (cs)
SK (1)	SK10842002A3 (cs)
TW (1)	TWI236481B (cs)
WO (1)	WO2001055175A2 (cs)
YU (1)	YU51202A (cs)
ZA (1)	ZA200205990B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH695999A5 (de) *	2002-02-28	2006-11-15	Wilex Ag	Verfahren zur Herstellung von 3- Amidinophenylalanin-Derivaten.
US20090215025A1 (en) *	2005-12-07	2009-08-27	Technische Universitat Munchen	Small peptidic and peptido-mimetic affinity ligands for factor viii and factor viii-like proteins
CN101774942B (zh) *	2010-01-27	2012-08-22	宁波武盛化学有限公司	制备n-乙酰基-dl-环己基甘氨酸的方法
US8558023B2 (en) *	2010-04-20	2013-10-15	Chiral Quest, Inc.	Enantioselective process for cycloalkenyl β-substituted alanines
JP5913352B2 (ja) *	2010-11-29	2016-04-27	高砂香料工業株式会社	不斉水素化触媒、およびそれを用いた光学活性カルボニル化合物の製造方法
CN115068469B (zh) *	2022-07-08	2024-02-27	深圳市小分子新药创新中心有限公司	Tigit抑制剂及其应用
CN115612702A (zh) *	2022-10-09	2023-01-17	深圳市茵诺圣生物科技有限公司	L-丙氨酸类非天然氨基酸3-(3-吡啶基)-l-丙氨酸的合成方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2916711A1 (de)	1979-04-25	1980-11-06	Behringwerke Ag	Blutgerinnungsfaktoren und verfahren zu ihrer herstellung
US4440679A (en) *	1980-03-05	1984-04-03	Cutter Laboratories, Inc.	Pasteurized therapeutically active protein compositions
US4623717A (en) *	1980-03-05	1986-11-18	Miles Laboratories, Inc.	Pasteurized therapeutically active protein compositions
SE9301916D0 (sv) *	1993-06-03	1993-06-03	Ab Astra	New peptides derivatives
UA44258C2 (uk) *	1993-10-15	2002-02-15	Рон-Пуленк Рорер Фармасьютікалз Інк.	Антитромботичні азациклоалкілалканоілпептиди та псевдопептиди, фармацевтична композиція, що їх містить, спосіб профілактики або лікування тромбозу у ссавців (варіанти)
EP1384725A3 (en) *	1994-04-26	2007-02-21	Aventis Pharmaceuticals Inc.	Factor Xa inhibitors
US5849510A (en)	1994-04-26	1998-12-15	Selectide Corporation	Factor Xa inhibitors
TR199801107T2 (xx) *	1995-12-20	1998-10-21	Hoechst Marion Roussel Inc.	N-Asetil (L)-4-siyanofenilalanin Ac (L)-phe (4-CN)-OH ve N-Asetil-(L)-p-amidinofenilalanin-sikloheksil-glisin -�-(3-N-metilpiridinyum)-alanin Ac-(L)-pAph-Chg-PalMe (3) -NH2'nin haz�rlanmas� i�in yeni bir i�lem.
DE19856443A1 (de)	1998-12-08	2000-06-21	Centeon Pharma Gmbh	Stabilisiertes Antithrombin III-Präparat

2001
- 2001-01-18 RU RU2002123046/04A patent/RU2250212C2/ru not_active IP Right Cessation
- 2001-01-18 AT AT01911497T patent/ATE325810T1/de active
- 2001-01-18 YU YU51202A patent/YU51202A/sh unknown
- 2001-01-18 KR KR1020027009583A patent/KR100758141B1/ko not_active Expired - Fee Related
- 2001-01-18 IL IL15089701A patent/IL150897A0/xx active IP Right Grant
- 2001-01-18 SK SK1084-2002A patent/SK10842002A3/sk unknown
- 2001-01-18 EP EP01911497A patent/EP1254159B9/en not_active Expired - Lifetime
- 2001-01-18 DE DE60119491T patent/DE60119491T2/de not_active Expired - Lifetime
- 2001-01-18 ES ES01911497T patent/ES2262632T3/es not_active Expired - Lifetime
- 2001-01-18 CN CNB018041523A patent/CN1176104C/zh not_active Expired - Fee Related
- 2001-01-18 MX MXPA02006762A patent/MXPA02006762A/es active IP Right Grant
- 2001-01-18 WO PCT/EP2001/000523 patent/WO2001055175A2/en not_active Ceased
- 2001-01-18 EE EEP200200410A patent/EE200200410A/xx unknown
- 2001-01-18 HR HRP20020631 patent/HRP20020631A2/hr not_active Application Discontinuation
- 2001-01-18 CZ CZ20022583A patent/CZ20022583A3/cs unknown
- 2001-01-18 NZ NZ520427A patent/NZ520427A/en unknown
- 2001-01-18 PL PL01356801A patent/PL356801A1/xx unknown
- 2001-01-18 DK DK01911497T patent/DK1254159T3/da active
- 2001-01-18 JP JP2001561027A patent/JP4778181B2/ja not_active Expired - Fee Related
- 2001-01-18 BR BR0107804-6A patent/BR0107804A/pt not_active Application Discontinuation
- 2001-01-18 PT PT01911497T patent/PT1254159E/pt unknown
- 2001-01-18 AR ARP010100225A patent/AR027246A1/es unknown
- 2001-01-18 HU HU0301986A patent/HUP0301986A2/hu unknown
- 2001-01-18 CA CA2398497A patent/CA2398497C/en not_active Expired - Fee Related
- 2001-01-18 AU AU40516/01A patent/AU779722B2/en not_active Ceased
- 2001-01-26 US US09/769,487 patent/US20010031858A1/en not_active Abandoned
- 2001-03-07 TW TW090101207A patent/TWI236481B/zh not_active IP Right Cessation
2002
- 2002-07-24 IL IL150897A patent/IL150897A/en not_active IP Right Cessation
- 2002-07-26 NO NO20023577A patent/NO20023577L/no unknown
- 2002-07-26 ZA ZA200205990A patent/ZA200205990B/en unknown
2004
- 2004-06-17 US US10/869,076 patent/US7084250B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP1254159A2 (en)	2002-11-06
NO20023577D0 (no)	2002-07-26
ZA200205990B (en)	2003-04-30
AU4051601A (en)	2001-08-07
CA2398497A1 (en)	2001-08-02
DE60119491T2 (de)	2006-11-16
AU779722B2 (en)	2005-02-10
PL356801A1 (en)	2004-07-12
EE200200410A (et)	2003-12-15
ATE325810T1 (de)	2006-06-15
NZ520427A (en)	2004-02-27
CN1176104C (zh)	2004-11-17
HK1051866A1 (en)	2003-08-22
EP1254159B9 (en)	2006-06-28
JP4778181B2 (ja)	2011-09-21
HUP0301986A2 (hu)	2003-09-29
EP1254159B1 (en)	2006-05-10
ES2262632T3 (es)	2006-12-01
US20040225109A1 (en)	2004-11-11
KR20030019306A (ko)	2003-03-06
CN1396928A (zh)	2003-02-12
KR100758141B1 (ko)	2007-09-13
WO2001055175A2 (en)	2001-08-02
CA2398497C (en)	2011-04-26
SK10842002A3 (sk)	2003-04-01
CZ20022583A3 (cs)	2002-10-16
IL150897A (en)	2008-08-07
US20010031858A1 (en)	2001-10-18
JP2003523364A (ja)	2003-08-05
HRP20020631A2 (en)	2004-12-31
NO20023577L (no)	2002-08-28
US7084250B2 (en)	2006-08-01
WO2001055175A3 (en)	2002-02-21
RU2250212C2 (ru)	2005-04-20
DE60119491D1 (de)	2006-06-14
BR0107804A (pt)	2002-10-22
TWI236481B (en)	2005-07-21
MXPA02006762A (es)	2002-10-23
PT1254159E (pt)	2006-07-31
DK1254159T3 (da)	2006-09-11
YU51202A (sh)	2005-11-28
RU2002123046A (ru)	2004-01-10
AR027246A1 (es)	2003-03-19

Legal Events

Date	Code	Title	Description
2009-06-15	FF	Patent granted
2009-06-15	KB	Patent renewed

Publication	Publication Date	Title
HU0103291D0 (en)	2001-10-28	Process for the preparation of citalopram
IL187126A0 (en)	2008-02-09	Process for the preparation of 4 - haloalkylnicotinonitriles
IL143106A (en)	2005-11-20	Process for the preparation of diphenylmethylthioacetamide
AU8824201A (en)	2002-02-25	Process for the preparation of dinapsoline
AU6259701A (en)	2002-01-02	Process for the preparation of pyrazolopyrimidinones
IL150897A0 (en)	2003-02-12	Process for the preparation of acetyl-amidiniophenylalanyl cyclohexylglycyl-pyridinioalaninamides
HUP0202865A3 (en)	2005-01-28	Process for the preparation of 2-cyanopyridines
HUP0303025A3 (en)	2012-01-30	Process for the preparation of arylethanoldiamines
EG22846A (en)	2003-09-30	Process for the preparation of urea
IL138691A (en)	2005-03-20	Process for the preparation of 3-acyl-indoles
IL190807A0 (en)	2008-11-03	Process for the preparation of 2-aminoethylpyridines
SI1127876T1 (en)	2003-02-28	Process for the preparation of isoindoline
IL137364A (en)	2005-08-31	Process for the preparation of 6,6-dimethylhept-1-en-4-yn-3-ol
AU5462901A (en)	2001-08-27	Process for the preparation of (pyridinylidene)-phthalides
PL368905A1 (en)	2005-04-04	Process for the preparation of beta-ionylideneacetaldehyde
EG22758A (en)	2003-07-30	Process for the preparation of urea
GB0012249D0 (en)	2000-07-12	Process for the preparation of 11-oxaprostaglandins
AU2166302A (en)	2002-04-22	Process for the preparation of thiophenols
HUP0301207A3 (en)	2006-02-28	Novel process for the preparation of pyrazolopyrimidinones
GB0012996D0 (en)	2000-07-19	Process for the preparation of endo-5-norbornene-2-ol
GB0028881D0 (en)	2001-01-10	Process for the preparation of endo-5-norbornene-2-ol
HU0003616D0 (en)	2000-11-28	Process for the preparation of pyridyl-ketone
PL352099A1 (en)	2003-07-28	Process for the preparation of tetrafluorohalogenbenzenes
AU2002231651A1 (en)	2002-06-24	Process for the preparation of morpholinones
GB0015462D0 (en)	2000-08-16	Novel process for the preparation of pyrazolopyrimidinones