IL155482A0 - Metabolic rate shifts in fermentations expressing recombinant proteins - Google Patents

Metabolic rate shifts in fermentations expressing recombinant proteins

Info

Publication number
IL155482A0
IL155482A0 IL15548201A IL15548201A IL155482A0 IL 155482 A0 IL155482 A0 IL 155482A0 IL 15548201 A IL15548201 A IL 15548201A IL 15548201 A IL15548201 A IL 15548201A IL 155482 A0 IL155482 A0 IL 155482A0
Authority
IL
Israel
Prior art keywords
host cells
recombinant host
metabolic rate
recombinant proteins
polypeptide
Prior art date
Application number
IL15548201A
Other languages
English (en)
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22928808&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL155482(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of IL155482A0 publication Critical patent/IL155482A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Fertilizers (AREA)
IL15548201A 2000-11-03 2001-11-01 Metabolic rate shifts in fermentations expressing recombinant proteins IL155482A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24596200P 2000-11-03 2000-11-03
PCT/US2001/045623 WO2002040697A2 (en) 2000-11-03 2001-11-01 Metabolic rate shifts in fermentations expressing recombinant proteins

Publications (1)

Publication Number Publication Date
IL155482A0 true IL155482A0 (en) 2003-11-23

Family

ID=22928808

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15548201A IL155482A0 (en) 2000-11-03 2001-11-01 Metabolic rate shifts in fermentations expressing recombinant proteins
IL155482A IL155482A (en) 2000-11-03 2003-04-15 Method for increasing product yield of a mammalian polypeptide produced by recombinant bacterial host cells

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL155482A IL155482A (en) 2000-11-03 2003-04-15 Method for increasing product yield of a mammalian polypeptide produced by recombinant bacterial host cells

Country Status (13)

Country Link
US (1) US6716602B2 (de)
EP (1) EP1332222B1 (de)
JP (1) JP4878724B2 (de)
AT (1) ATE426674T1 (de)
AU (1) AU3944002A (de)
CA (1) CA2426100A1 (de)
CY (1) CY1110494T1 (de)
DE (1) DE60138127D1 (de)
DK (1) DK1332222T3 (de)
ES (1) ES2324645T3 (de)
IL (2) IL155482A0 (de)
PT (1) PT1332222E (de)
WO (1) WO2002040697A2 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7294481B1 (en) 1999-01-05 2007-11-13 Immunex Corporation Method for producing recombinant proteins
ES2529254T3 (es) * 2002-05-30 2015-02-18 Cargill Inc. Proceso de fermentación usando velocidades de incorporación de oxígeno específicas como un control del proceso
GB0321100D0 (en) 2003-09-09 2003-10-08 Celltech R&D Ltd Biological products
AU2009290563A1 (en) 2008-09-15 2010-03-18 Genentech, Inc. Compositions and methods for regulating cell osmolarity
ES2610356T3 (es) 2009-02-03 2017-04-27 Amunix Operating Inc. Polipéptidos recombinantes extendidos y composiciones que comprenden los mismos
SI2493922T1 (sl) 2009-10-26 2017-06-30 F. Hoffmann-La Roche Ag Postopek za proizvodnjo glikoziliranega imunoglobulina
GB2482536B (en) 2010-08-05 2013-07-24 Hera Pharmaceuticals Inc Expression of antibody or a fragment thereof in lactobacillus
ES3011307T3 (en) 2012-02-23 2025-04-07 Juno Therapeutics Gmbh Chromatographic isolation of cells and other complex biological materials
CN104662161A (zh) 2012-09-19 2015-05-27 弗·哈夫曼-拉罗切有限公司 用于防止正亮氨酸错误地掺入蛋白质中的方法和组合物
AU2014306074B2 (en) 2013-08-05 2018-08-30 Greenlight Biosciences, Inc. Engineered proteins with a protease cleavage site
WO2015178466A1 (ja) * 2014-05-21 2015-11-26 味の素株式会社 フィブロイン様タンパク質の製造法
CN104164465B (zh) * 2014-07-14 2017-07-04 北京泰德制药股份有限公司 一种表达重组蛋白的发酵工艺
WO2016073791A1 (en) * 2014-11-05 2016-05-12 Genentech, Inc. Methods of producing two chain proteins in bacteria
US10066002B2 (en) * 2014-11-05 2018-09-04 Genentech, Inc. Methods of producing two chain proteins in bacteria
JP2018516081A (ja) 2015-05-29 2018-06-21 カーギル・インコーポレイテッド 配糖体を産生するための熱処理
EP3303552A4 (de) 2015-05-29 2019-01-16 Cargill, Incorporated Fermentationsverfahren zur herstellung steviolglykosiden mit mehrphasiger zuführung
EP4134442A1 (de) 2015-05-29 2023-02-15 Cargill, Incorporated Fermentationsverfahren zur herstellung von steviolglykosiden mithilfe von hohem ph-wert
CN107920548A (zh) 2015-08-06 2018-04-17 嘉吉公司 用于产生甜菊醇糖苷的发酵方法
EP3365453A2 (de) 2015-10-22 2018-08-29 Juno Therapeutics GmbH Verfahren, kits, mittel und vorrichtungen zur transduktion
MX2018004875A (es) 2015-10-22 2018-08-01 Juno Therapeutics Gmbh Metodos para cultivar celulas y kits y aparatos para ello.
US11261462B2 (en) 2016-01-27 2022-03-01 Just-Evotec Biologics, Inc. Inducible expression from transposon-based vectors and uses
US11098310B2 (en) 2016-01-27 2021-08-24 Just-Evotec Biologics, Inc. Expression from transposon-based vectors and uses
JP6937309B2 (ja) 2016-01-27 2021-09-22 ジャスト−エヴォテック バイオロジックス、インコーポレイテッド ハイブリッドプロモーターおよびその使用
JP7339160B2 (ja) 2017-04-27 2023-09-05 ジュノ セラピューティクス ゲーエムベーハー オリゴマー粒子試薬およびその使用方法
SG11202104355SA (en) 2018-10-31 2021-05-28 Juno Therapeutics Gmbh Methods for selection and stimulation of cells and apparatus for same

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4565785A (en) 1978-06-08 1986-01-21 The President And Fellows Of Harvard College Recombinant DNA molecule
US4673641A (en) 1982-12-16 1987-06-16 Molecular Genetics Research And Development Limited Partnership Co-aggregate purification of proteins
US4710473A (en) 1983-08-10 1987-12-01 Amgen, Inc. DNA plasmids
US4738921A (en) 1984-09-27 1988-04-19 Eli Lilly And Company Derivative of the tryptophan operon for expression of fused gene products
US4795706A (en) 1985-01-31 1989-01-03 Eli Lilly And Company Novel expression control sequences
US5612198A (en) * 1990-09-04 1997-03-18 The Salk Institute Production of insulin-like growth factor-1 in methylotrophic yeast cells
US5342763A (en) 1992-11-23 1994-08-30 Genentech, Inc. Method for producing polypeptide via bacterial fermentation
CA2153445C (en) * 1994-09-08 2002-05-21 Ashok Raj Saxena Video optimized media streamer user interface
US5789199A (en) * 1994-11-03 1998-08-04 Genentech, Inc. Process for bacterial production of polypeptides
US5639635A (en) 1994-11-03 1997-06-17 Genentech, Inc. Process for bacterial production of polypeptides
US5790423A (en) * 1995-06-14 1998-08-04 Audible, Inc. Interactive audio transmission receiving and playback system
AR005035A1 (es) 1995-12-11 1999-04-07 Merck Patent Ges Mit Beschränkter Haftung Procedimiento para preparar proteinas recombinantes en e. coli, mediante fermentacion con gran concentracion de celulas.
US6615192B1 (en) * 1999-03-12 2003-09-02 Matsushita Electric Industrial Co., Ltd. Contents copying system, copying method, computer-readable recording medium and disc drive copying contents but not a cipher key via a host computer
ID27746A (id) * 1999-05-28 2001-04-26 Matsushita Electric Industrial Co Ltd Kartu semikonduktor, peralatan playback, peralatan perekaman, metoda playback, metoda perekaman, dan media perekaman dapat dibaca kombuter
DE19943919B4 (de) * 1999-09-14 2004-05-27 Pharmacia Ab Verfahren zur Steigerung der Ausbeute von rekombinanten Proteinen in mikrobiellen Fermentationsprozessen

Also Published As

Publication number Publication date
WO2002040697A3 (en) 2003-03-13
US6716602B2 (en) 2004-04-06
US20020164700A1 (en) 2002-11-07
JP4878724B2 (ja) 2012-02-15
ES2324645T3 (es) 2009-08-12
CA2426100A1 (en) 2002-05-23
EP1332222B1 (de) 2009-03-25
AU3944002A (en) 2002-05-27
PT1332222E (pt) 2009-06-30
JP2004517614A (ja) 2004-06-17
WO2002040697A2 (en) 2002-05-23
CY1110494T1 (el) 2015-04-29
DK1332222T3 (da) 2009-07-06
IL155482A (en) 2010-12-30
HK1054765A1 (en) 2003-12-12
ATE426674T1 (de) 2009-04-15
DE60138127D1 (de) 2009-05-07
EP1332222A2 (de) 2003-08-06

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