ATE367436T1 - Verfahren und materialien zur produktion von d- milchsäure in hefe - Google Patents

Verfahren und materialien zur produktion von d- milchsäure in hefe

Info

Publication number
ATE367436T1
ATE367436T1 AT03731489T AT03731489T ATE367436T1 AT E367436 T1 ATE367436 T1 AT E367436T1 AT 03731489 T AT03731489 T AT 03731489T AT 03731489 T AT03731489 T AT 03731489T AT E367436 T1 ATE367436 T1 AT E367436T1
Authority
AT
Austria
Prior art keywords
yeast
producing
materials
lactic acid
microorganism
Prior art date
Application number
AT03731489T
Other languages
English (en)
Inventor
Vineet Rajgarhia
Catherine Dundon
Stacey Olson
Pirkko Suominen
Ben Hause
Original Assignee
Natureworks Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Natureworks Llc filed Critical Natureworks Llc
Application granted granted Critical
Publication of ATE367436T1 publication Critical patent/ATE367436T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56—Lactic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C12P7/625—Polyesters of hydroxy carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/37—Assays involving biological materials from specific organisms or of a specific nature from fungi
    • G01N2333/39—Assays involving biological materials from specific organisms or of a specific nature from fungi from yeasts
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Botany (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT03731489T 2002-05-30 2003-05-30 Verfahren und materialien zur produktion von d- milchsäure in hefe ATE367436T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US38433302P 2002-05-30 2002-05-30

Publications (1)

Publication Number Publication Date
ATE367436T1 true ATE367436T1 (de) 2007-08-15

Family

ID=29712012

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03731489T ATE367436T1 (de) 2002-05-30 2003-05-30 Verfahren und materialien zur produktion von d- milchsäure in hefe

Country Status (15)

Country Link
US (7) US7232664B2 (de)
EP (4) EP1513940A4 (de)
JP (4) JP2005528106A (de)
CN (4) CN1735683B (de)
AT (1) ATE367436T1 (de)
AU (4) AU2003240481B8 (de)
BR (4) BRPI0311517A2 (de)
CA (3) CA2488196A1 (de)
DE (1) DE60315028T2 (de)
DK (1) DK2878675T3 (de)
ES (3) ES2642928T3 (de)
PT (1) PT1513923E (de)
UA (2) UA80976C2 (de)
WO (3) WO2003102201A2 (de)
ZA (3) ZA200409530B (de)

Families Citing this family (122)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1294728B1 (it) * 1997-09-12 1999-04-12 Biopolo S C A R L Ceppi di lievito per la riproduzione di acido lattico
US20070031950A1 (en) * 1998-09-11 2007-02-08 Winkler Aaron A Production of D-lactic acid with yeast
US7141410B2 (en) * 2000-11-22 2006-11-28 Natureworks Llc Methods and materials for the production of organic products in cells of Candida species
WO2003102201A2 (en) 2002-05-30 2003-12-11 Cargill Dow Llc Methods and materials for the production of d-lactic acid in yeast
DK2345662T3 (en) 2003-05-02 2016-08-15 Cargill Inc Genetically modified yeast species and fermentation processes using genetically modified yeast
JP4460876B2 (ja) * 2003-11-07 2010-05-12 株式会社豊田中央研究所 有機酸存在下におけるプロモーター及びその利用
US20050112737A1 (en) * 2003-11-20 2005-05-26 A. E. Staley Manufacturing Co. Lactic acid producing yeast
JP4806904B2 (ja) * 2004-07-09 2011-11-02 トヨタ自動車株式会社 乳酸生産方法
JP2006296377A (ja) * 2005-04-25 2006-11-02 Toyota Central Res & Dev Lab Inc 有機酸生産用形質転換体
WO2007032792A2 (en) 2005-06-02 2007-03-22 Cargill, Inc. Genetically modified yeast of the species issatchenkia orientalis and closely related species and fermentation processes using same
ES2401339T3 (es) 2005-08-10 2013-04-18 University Of Florida Research Foundation, Inc. Materiales y métodos para producción eficiente de ácido láctico
JP4692173B2 (ja) * 2005-09-13 2011-06-01 東レ株式会社 Ｄ−乳酸デヒドロゲナーゼ活性を有するポリペプチド、これをコードする遺伝子およびｄ−乳酸の製造方法
US7718405B2 (en) * 2005-09-19 2010-05-18 American Air Liquide, Inc. Use of pure oxygen in viscous fermentation processes
EP1929009A2 (de) 2005-09-22 2008-06-11 Tate & Lyle Ingredients Americas, Inc. Verbesserte stämme zur herstellung organischer säuren
EP1975232A4 (de) * 2005-10-14 2009-07-29 Toray Industries Hefe und verfahren zur herstellung von l-milchsäure
JP5121070B2 (ja) 2005-11-23 2013-01-16 ネイチャーワークス・エル・エル・シー Ｌ−又はｄ−ラクタート：フェリチトクロームｃ酸化還元酵素遺伝子が機能しない乳酸産生酵母
WO2007085443A2 (en) 2006-01-24 2007-08-02 Purac Biochem Bv Genetic modification of homolactic thermophilic bacilli
EP2001992B1 (de) 2006-03-13 2016-07-20 Cargill Inc. Hefezellen mit unterbrochenem weg von dihydroxyaceton-phosphate bis glycerin
JP5320692B2 (ja) * 2006-06-28 2013-10-23 東レ株式会社 酵母及びｌ−乳酸の製造方法
US20080064076A1 (en) * 2006-09-11 2008-03-13 Saucedo Victor M Dissolved Oxygen Profile to Increase Fermentation Productivity and Economics
JP5141126B2 (ja) * 2006-09-26 2013-02-13 東レ株式会社 連続発酵によるｄ−乳酸の製造方法
US8236994B2 (en) * 2006-10-31 2012-08-07 Metabolic Explorer Process for the biological production of 1,3-propanediol from glycerol with high yield
WO2008052596A1 (en) * 2006-10-31 2008-05-08 Metabolic Explorer Process for the biological production of n-butanol with high yield
JP2010512147A (ja) 2006-12-07 2010-04-22 マサチューセッツ インスティテュート オブ テクノロジー 包括的転写マシナリーエンジニアリング
JP5130826B2 (ja) * 2007-03-28 2013-01-30 東レ株式会社 連続発酵による乳酸の製造方法
JP2008283917A (ja) * 2007-05-18 2008-11-27 Toray Ind Inc 乳酸の製造方法
EP2217711B2 (de) 2007-09-20 2025-04-23 Amyris, Inc. Herstellung von isoprenoiden
CN101939426B (zh) * 2007-12-07 2014-01-08 东丽株式会社 乳酸脱氢酶表达盒、转化酵母和乳酸的制造方法
US8455239B2 (en) * 2007-12-23 2013-06-04 Gevo, Inc. Yeast organism producing isobutanol at a high yield
DK2235193T3 (da) * 2007-12-23 2016-02-29 Gevo Inc Gærorganisme, der producerer isobutanol med højt udbytte
EP2238098A4 (de) 2007-12-27 2016-06-01 Gevo Inc Rückgewinnung von höheren alkoholen aus verdünnten wässrigen lösungen
JP5992135B2 (ja) * 2008-02-04 2016-09-14 東レ株式会社 連続発酵による乳酸の製造方法
US20090235951A1 (en) * 2008-03-18 2009-09-24 Legrande W E Environmentally Responsible Dental Floss and Packaging
JP4963488B2 (ja) * 2008-04-23 2012-06-27 トヨタ自動車株式会社 変異体酵母及びこれを用いた物質生産方法
CN107267562A (zh) 2008-07-08 2017-10-20 帝斯曼知识产权资产管理有限公司 通过在低pH下发酵生产二羧酸
CA2738452C (en) 2008-10-03 2016-06-21 Metabolic Explorer Method for purifying an alcohol from a fermentation broth using a falling film, a wiped film, a thin film or a short path evaporator
JPWO2010084972A1 (ja) * 2009-01-23 2012-07-19 株式会社アグリバイオインダストリ Ｄ−乳酸の製造方法および乳酸においてｄ−乳酸の光学純度または対糖収率を高める方法
RU2553563C2 (ru) * 2009-06-03 2015-06-20 Торэй Индастриз, Инк. Полипептид, обладающий активностью d-лактатдегидрогеназы, полинуклеотид, кодирующий этот полипептид, и способ получения d-молочной кислоты
RU2012102626A (ru) * 2009-06-26 2013-08-10 Джево, Инк. Извлечение высших спиртов из разбавленных водных растворов
US20120156761A1 (en) 2009-07-02 2012-06-21 Verdezyne, Inc. Biological methods for preparing adipic acid
JPWO2011013721A1 (ja) * 2009-07-28 2013-01-10 三井化学株式会社 乳酸製造方法
CN102575235B (zh) 2009-07-30 2015-05-20 代谢探索者公司 用于通过发酵生产生物化学品的突变甲基乙二醛合酶(mgs)
EP3282017A1 (de) 2009-08-27 2018-02-14 DSM IP Assets B.V. Fermentationsverfahren zur herstellung von dicarbonsäuren
EP2485995A4 (de) * 2009-10-06 2015-12-02 Gevo Inc Integriertes verfahren zur selektiven umwandlung von erneuerbarem isobutanol in p-xylen
EA201201449A1 (ru) 2010-04-21 2013-03-29 ДСМ АйПи АССЕТС Б.В. Способ получения клеток, способных преобразовывать арабинозу
US9012190B2 (en) 2011-06-15 2015-04-21 Butamax Advanced Biofuels Llc Use of thiamine and nicotine adenine dinucleotide for butanol production
CA2807102C (en) 2010-07-31 2018-08-21 Myriant Corporation Improved fermentation process for the production of organic acids
EA201300455A1 (ru) 2010-10-13 2013-09-30 ДСМ АйПи АССЕТС Б.В. Полипептиды с пермеазной активностью
JP6061862B2 (ja) 2010-11-22 2017-01-18 カーギル，インコーポレイティド ３‐ヒドロキシプロピオン酸生産用の組成物及び方法
ES2645680T3 (es) 2010-11-22 2017-12-07 Cargill, Incorporated Células de levadura y proceso para convertir acetaldehído en etanol
US9605285B2 (en) 2011-01-25 2017-03-28 Cargill, Incorporated Compositions and methods for succinate production
BR112013024831A2 (pt) * 2011-03-29 2016-12-20 Nestec Sa derivado natural da cepa cncm i-1225 de lactobacillus johnsonii, deficiente na produção de ácido d=láctico e com um perfil imunológico mais incrementado
WO2012137201A1 (en) 2011-04-07 2012-10-11 Hcl Cleantech Ltd. Lignocellulose conversion processes and products
US9181563B2 (en) 2011-04-11 2015-11-10 Cargill, Incorporated Compositions and methods for increased ethanol production from biomass
CN103502267A (zh) 2011-04-22 2014-01-08 帝斯曼知识产权资产管理有限公司 能转化包括阿拉伯糖和木糖的糖的酵母细胞
US8343752B2 (en) 2011-05-03 2013-01-01 Verdezyne, Inc. Biological methods for preparing adipic acid
US8728798B2 (en) 2011-05-03 2014-05-20 Verdezyne, Inc. Biological methods for preparing adipic acid
CN102285664B (zh) * 2011-05-27 2013-06-19 广西崇左市湘桂糖业有限公司 模拟移动床分离l-乳酸和d-乳酸专用分子筛及其制备方法
TWI563093B (en) * 2011-08-11 2016-12-21 Mitsui Chemicals Inc Method of producing isopropyl alcohol by continuous culture
WO2013112939A2 (en) * 2012-01-25 2013-08-01 Cargill, Incorporated Methods for succinate production
JP6306519B2 (ja) * 2012-02-22 2018-04-04 ノボザイムス アクティーゼルスカブ 高度発酵制御
FR2988733B1 (fr) * 2012-03-27 2016-02-05 Carbios Microorganisme recombinant
KR101438882B1 (ko) 2012-04-24 2014-09-05 씨제이제일제당 (주) 신규한 ｄ형 젖산 생산균주
EP2878349B1 (de) 2012-05-03 2022-07-06 Virdia, LLC Fraktionierung eines Gemisches mittels sequenzieller simulierter Fliessbettchromatographie
US9493851B2 (en) 2012-05-03 2016-11-15 Virdia, Inc. Methods for treating lignocellulosic materials
WO2014003439A1 (ko) * 2012-06-26 2014-01-03 한국생명공학연구원 에탄올 생산 경로가 봉쇄된 클루이베로마이세스 막시아누스 균주 및 이의 용도
US9850507B2 (en) 2012-07-25 2017-12-26 Cargill, Incorporated Yeast cells having reductive TCA pathway from pyruvate to succinate and overexpressing an exogenous NAD(P)+ transhydrogenase enzyme
KR102253532B1 (ko) 2012-09-14 2021-05-18 피티티 글로벌 케미컬 퍼블릭 컴퍼니 리미티드 낮은 ph에서 발효에 의한 유기산의 제조
EP2909305B1 (de) 2012-10-16 2018-12-26 DSM IP Assets B.V. Zellen mit verbesserter pentoseumwandlung
WO2014072232A1 (en) 2012-11-07 2014-05-15 Dsm Ip Assets B.V. pH CONTROLLED YEAST PROPAGATION
WO2014076232A2 (en) 2012-11-19 2014-05-22 Novozymes A/S Isopropanol production by recombinant hosts using an hmg-coa intermediate
JP2015536669A (ja) 2012-11-30 2015-12-24 ノボザイムス，インコーポレイティド 組換え酵母による３−ヒドロキシプロピオン酸の生産
RU2710714C9 (ru) 2013-06-18 2020-10-06 Калиста, Инк. Композиции и способы для биологического получения лактата из с1-соединений с применением трансформантов лактат дегидрогеназы
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
BR112016001778A2 (pt) 2013-07-31 2017-09-05 Novozymes As Célula transgênica de levedura, composição, e, métodos de produção de 3-hp e de produção de ácido acrílico ou um sal do mesmo
US10337043B2 (en) 2014-01-16 2019-07-02 Calysta, Inc. Carbohydrate-enriched recombinant microorganisms
KR20150096019A (ko) * 2014-02-13 2015-08-24 삼성전자주식회사 유전자 조작 효율이 향상된 효모 세포 및 그의 용도
US9593350B2 (en) 2014-02-14 2017-03-14 Samsung Electronics Co., Ltd. Lactate dehydrogenase mutant, polynucleotide coding for the mutant, yeast cell including the polynucleotide, method of preparing the mutant, and method of producing the lactate using the same
JP6183263B2 (ja) * 2014-03-28 2017-08-23 王子ホールディングス株式会社 Ｄ−乳酸の精製のための工程が改良されたｄ−乳酸の製造方法
EP4056631A1 (de) 2014-05-16 2022-09-14 Carbios Verfahren zum recyceln gemischter kunststoffartikel
WO2016012429A1 (en) 2014-07-24 2016-01-28 Dsm Ip Assets B.V. Yeast cell with improved pentose transport
KR102245298B1 (ko) 2014-09-05 2021-04-27 삼성전자주식회사 증가된 edc 활성을 갖고 락테이트 생산능을 갖는 유전적으로 조작된 효모 세포, 그를 제조하는 방법, 그를 제조하는 방법, 및 그를 사용하여 락테이트를 생산하는 방법
US10214754B2 (en) 2014-10-10 2019-02-26 Jmtc Enzyme Corporation Transformant and its production process, and method for producing lactic acid
WO2016062695A1 (en) 2014-10-21 2016-04-28 Carbios Polypeptide having a polyester degrading activity and uses thereof
CN107429274A (zh) 2014-11-20 2017-12-01 全循环生物塑料有限公司 从有机废物生产聚羟基链烷酸酯共聚物
JP6711278B2 (ja) * 2014-11-28 2020-06-17 味の素株式会社 イソプレノイド化合物の製造方法
WO2016100910A1 (en) 2014-12-19 2016-06-23 Novozymes A/S Recombinant host cells for the production of 3-hydroxypropionic acid
US10626242B2 (en) 2014-12-19 2020-04-21 Carbios Plastic compound and preparation process
SE538899C2 (en) 2015-02-03 2017-01-31 Stora Enso Oyj Method for treating lignocellulosic materials
EP3262161B1 (de) 2015-02-27 2021-06-30 Novozymes A/S Mutante wirtszellen zur herstellung von 3-hydroxypropionsäure
US10508269B2 (en) 2015-03-13 2019-12-17 Carbios Polypeptide having a polyester degrading activity and uses thereof
US20180179499A1 (en) 2015-06-04 2018-06-28 Bioamber Inc. Biobased production of functionalized alpha-substituted acrylates and c4-dicarboxylates
MY192862A (en) 2015-06-12 2022-09-13 Carbios Masterbatch composition comprising a high concentration of biological entities
EP3341475A1 (de) 2015-08-24 2018-07-04 Novozymes A/S Beta-alanin-aminotransferasen zur herstellung von 3-hydroxypropionsäure
EP3394264A1 (de) 2015-12-21 2018-10-31 Carbios Polymilchsäure produzierende rekombinante hefezellen und verwendungen davon
KR102364794B1 (ko) 2016-05-19 2022-02-18 까르비오 플라스틱 제품을 분해하기 위한 방법
ES2899973T3 (es) 2016-07-13 2022-03-15 Dsm Ip Assets Bv Malato deshidrogenasas
EP3577227A4 (de) 2017-02-02 2020-12-30 Cargill Inc. Genetisch veränderte zellen, die c6-c10-fettsäurederivate produzieren
WO2019036202A1 (en) 2017-08-17 2019-02-21 Cargill, Incorporated ISSATCHENKIA ORIENTALIS HAPLOID GENETICALLY MODIFIED
EP3752627A4 (de) * 2018-02-16 2021-12-22 PTT Global Chemical Public Company Limited Mikroorganismen und verfahren zur herstellung von milchsäure
WO2019191767A1 (en) 2018-03-30 2019-10-03 Invista Textiles (U.K.) Limited High hydrogen utilization and gas recycle
CN111836898B (zh) * 2018-03-30 2024-02-23 英威达纺织（英国）有限公司 用于在连续有氧发酵中控制溶解氧浓度的方法
KR102140596B1 (ko) 2018-04-17 2020-08-04 에스케이이노베이션 주식회사 유기산 내성 효모 유래 신규 프로모터 및 이를 이용한 목적유전자의 발현방법
KR102140597B1 (ko) 2018-04-17 2020-08-03 에스케이이노베이션 주식회사 에탄올 생산 경로가 억제된 내산성 효모 및 이를 이용한 젖산의 제조방법
WO2019213108A1 (en) 2018-05-02 2019-11-07 Invista Textiles (U.K.) Ltd. Methods for controlling limitation conditions in product biosynthesis for non-phb generating cupriavidus or ralstonia
WO2019213033A1 (en) 2018-05-02 2019-11-07 Invista North America S.A.R.L. Materials and methods for maximizing biosynthesis through alteration of pyruvate-acetyl-coa-tca balance in species of the genera ralstonia and cupriavidus and organisms related thereto
TWI719317B (zh) * 2018-06-13 2021-02-21 遠東新世紀股份有限公司 用於生產乳酸的方法
CN109097293B (zh) * 2018-07-13 2021-10-26 广东利世康低碳科技有限公司 一种能降解利用餐厨废弃物生成乳酸的基因重组毕赤酵母
KR102736070B1 (ko) 2018-10-08 2024-12-02 에스케이이노베이션 주식회사 알코올 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법
CN113166752B (zh) 2018-11-30 2024-08-02 株式会社Co2资源化研究所 产乳酸的嗜氢菌属细菌转化体
WO2021028993A1 (ja) 2019-08-09 2021-02-18 株式会社Ｃｏ２資源化研究所 乳酸を生成する遺伝子組換えヒドロゲノフィラス属細菌
US12018245B2 (en) * 2019-08-19 2024-06-25 Ptt Global Chemical Public Company Limited Yeast having improvement of lactic acid tolerance and use thereof
TWI730383B (zh) * 2019-08-21 2021-06-11 遠東新世紀股份有限公司 重組型假絲酵母菌菌株及其製備方法與用途
KR20210041903A (ko) 2019-10-08 2021-04-16 에스케이이노베이션 주식회사 락테이트 대사 및 알코올 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법
KR20210128742A (ko) 2020-04-17 2021-10-27 에스케이이노베이션 주식회사 글리세롤 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법
KR20210158676A (ko) 2020-06-24 2021-12-31 에스케이이노베이션 주식회사 젖산 생산능이 증가된 재조합 내산성 효모
RU2752896C1 (ru) * 2020-12-04 2021-08-11 Федеральное государственное бюджетное учреждение "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Национального исследовательского центра "Курчатовский институт" - ГосНИИгенетика) Штамм дрожжей Schizosaccharomyces pombe, продуцирующий L-молочную кислоту, содержащий в составе хромосомы гены трех различных гетерологичных лактатдегидрогеназ
KR102287114B1 (ko) * 2021-01-25 2021-08-06 씨제이제일제당 주식회사 신규한 사이토신 퍼미에이즈 변이체 및 이를 이용한 l-트립토판 생산 방법
WO2022241027A1 (en) * 2021-05-13 2022-11-17 Lygos, Inc. Recombinant host cells and methods for producing l-lactic acid
CN113430127B (zh) * 2021-07-07 2024-01-12 江南大学 一种产l-乳酸的重组菌及其应用
CN113736814A (zh) * 2021-09-29 2021-12-03 上海交通大学 生产聚乳酸的基因工程菌株及生产聚乳酸的方法
US12049660B2 (en) 2021-11-03 2024-07-30 Wisconsin Alumni Research Foundation Gene duplications for crabtree-warburg-like aerobic xylose fermentation

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3384553A (en) * 1965-04-08 1968-05-21 Ceskoslovenska Akademie Ved Method and equipment for aerobic fermentation on liquid culture mediums
IL39710A (en) 1972-06-19 1975-04-25 Imi Inst For Res & Dev Recovery of acids from aqueous solutions by solvent extraction
US4064015A (en) * 1975-05-12 1977-12-20 New Brunswick Scientific Co., Inc. Control of biosynthesis in submerged culture
US4771001A (en) 1986-03-27 1988-09-13 Neurex Corp. Production of lactic acid by continuous fermentation using an inexpensive raw material and a simplified method of lactic acid purification
US5210296A (en) 1990-11-19 1993-05-11 E. I. Du Pont De Nemours And Company Recovery of lactate esters and lactic acid from fermentation broth
US5132456A (en) 1991-05-07 1992-07-21 The Regents Of The University Of California Sorption of carboxylic acid from carboxylic salt solutions at PHS close to or above the pKa of the acid, with regeneration with an aqueous solution of ammonia or low-molecular-weight alkylamine
JP3012377B2 (ja) * 1991-10-11 2000-02-21 名糖産業株式会社 低耐熱性プロテアーゼとその関連物及びその生産法
US5142023A (en) * 1992-01-24 1992-08-25 Cargill, Incorporated Continuous process for manufacture of lactide polymers with controlled optical purity
US5247059A (en) * 1992-01-24 1993-09-21 Cargill, Incorporated Continuous process for the manufacture of a purified lactide from esters of lactic acid
US5420304A (en) 1992-03-19 1995-05-30 Biopak Technology, Ltd. Method to produce cyclic esters
FR2693463B1 (fr) * 1992-07-08 1994-09-02 Rhone Poulenc Rorer Sa Promoteur de levure et son utilisation.
US5338822A (en) 1992-10-02 1994-08-16 Cargill, Incorporated Melt-stable lactide polymer composition and process for manufacture thereof
AT398982B (de) 1993-02-18 1995-02-27 Vogelbusch Gmbh Verfahren zur abtrennung und reinigung von milchsäure
US5510526A (en) 1993-06-29 1996-04-23 Cargill, Incorporated Lactic acid production, separation and/or recovery process
IL109003A (en) 1994-03-16 1999-09-22 Yissum Res Dev Co Process and extractant composition for extracting water-soluble carboxylic and mineral acids
JPH08173170A (ja) 1994-05-25 1996-07-09 Kirin Brewery Co Ltd キャンディダ・ユティリス酵母の形質転換系、およびそれによる異種遺伝子の発現
EP0875579B1 (de) * 1997-05-03 2007-06-27 Societe Des Produits Nestle S.A. Herstellung von L(+)-Lactat
IT1294728B1 (it) * 1997-09-12 1999-04-12 Biopolo S C A R L Ceppi di lievito per la riproduzione di acido lattico
US6229046B1 (en) * 1997-10-14 2001-05-08 Cargill, Incorported Lactic acid processing methods arrangements and products
US6046002A (en) * 1998-01-05 2000-04-04 The Board Of Trustees Of The Leland Stanford Junior University Highly parallel and sensitive method for identifying drugs and drug targets
AU1722800A (en) * 1998-11-18 2000-06-05 University Of Akron, The Production of biological materials by simultaneous aerobic and anaerobic respiration
BR0010806B1 (pt) * 1999-05-21 2014-02-18 Métodos e materiais para a síntese de produtos orgânicos
US6268189B1 (en) * 2000-03-24 2001-07-31 The United States Of America As Represented By The Secretary Of Agriculture Fungal lactate dehydrogenase gene and constructs for the expression thereof
JP2002136293A (ja) * 2000-08-23 2002-05-14 Toray Ind Inc 微生物およびｄ−乳酸の製造方法
WO2002040697A2 (en) * 2000-11-03 2002-05-23 Genentech, Inc. Metabolic rate shifts in fermentations expressing recombinant proteins
JP2004521619A (ja) 2000-11-22 2004-07-22 カージル ダウ ポリマーズ エルエルシー 有機生成物の合成のための方法及び材料
US7141410B2 (en) * 2000-11-22 2006-11-28 Natureworks Llc Methods and materials for the production of organic products in cells of Candida species
KR100426990B1 (ko) * 2001-06-27 2004-04-13 삼성전자주식회사 외부의 코드에 따라 프로그래머블하게 기준 전압을 발생시키는 기준 전압 발생 회로
US8039238B2 (en) * 2002-03-11 2011-10-18 Toyota Jidosha Kabushiki Kaisha Method of controlling ethanol production and mass production of lactic acid and transformant therefor
WO2003102201A2 (en) 2002-05-30 2003-12-11 Cargill Dow Llc Methods and materials for the production of d-lactic acid in yeast
US20070105202A1 (en) * 2003-05-22 2007-05-10 Nobuhiro Ishida Dna encoding a protein having d-lactate dehydrogenase activity and uses thereof

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