IL161966A0 - Aryloxyphenyl and arylsulfanylphenyl - Google Patents
Aryloxyphenyl and arylsulfanylphenylInfo
- Publication number
- IL161966A0 IL161966A0 IL16196602A IL16196602A IL161966A0 IL 161966 A0 IL161966 A0 IL 161966A0 IL 16196602 A IL16196602 A IL 16196602A IL 16196602 A IL16196602 A IL 16196602A IL 161966 A0 IL161966 A0 IL 161966A0
- Authority
- IL
- Israel
- Prior art keywords
- arylsulfanylphenyl
- aryloxyphenyl
- compounds
- valuable
- substituents
- Prior art date
Links
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000004471 Glycine Substances 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34265301P | 2001-12-20 | 2001-12-20 | |
| DKPA200101927 | 2001-12-20 | ||
| PCT/DK2002/000859 WO2003053942A1 (en) | 2001-12-20 | 2002-12-16 | Aryloxyphenyl and arylsulfanylphenyl derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL161966A0 true IL161966A0 (en) | 2005-11-20 |
Family
ID=26069114
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL16196602A IL161966A0 (en) | 2001-12-20 | 2002-12-16 | Aryloxyphenyl and arylsulfanylphenyl |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7067501B2 (de) |
| EP (1) | EP1458689B1 (de) |
| JP (1) | JP2005513128A (de) |
| CN (1) | CN100457738C (de) |
| AT (1) | ATE359276T1 (de) |
| AU (1) | AU2002351734A1 (de) |
| CA (1) | CA2467118A1 (de) |
| DE (1) | DE60219521T2 (de) |
| ES (1) | ES2280595T3 (de) |
| HU (1) | HUP0402320A2 (de) |
| IL (1) | IL161966A0 (de) |
| IS (1) | IS7258A (de) |
| MX (1) | MXPA04005989A (de) |
| NO (1) | NO20042885L (de) |
| WO (1) | WO2003053942A1 (de) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA81749C2 (uk) | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну |
| BRPI0413587A (pt) * | 2003-08-21 | 2006-10-17 | Lundbeck & Co As H | usos de um composto e de um inibidor de glyt-1, composição farmacêutica, kit, e, método para o tratamento de doença |
| WO2005058317A1 (en) * | 2003-12-18 | 2005-06-30 | Glaxo Group Limited | Glycine transporter-1 inhibirors |
| WO2005058885A2 (en) * | 2003-12-18 | 2005-06-30 | Glaxo Group Limited | Piperidine derivatives and their use as glycine transporter inhibitors |
| ES2295963T3 (es) | 2004-01-08 | 2008-04-16 | F. Hoffmann-La Roche Ag | Derivados diaza-espiropiperidina como inhibidores del transportador 1 de glicina y transportador 2 de glicina. |
| WO2006000222A2 (en) * | 2004-06-24 | 2006-01-05 | H. Lundbeck A/S | The combination of an antipsychotic and a glycine transporter type i inhibitor for the treatment of schizophrenia |
| US7485637B2 (en) * | 2005-01-04 | 2009-02-03 | Hoffmann-La Roche Inc. | Benzoyl-tetrahydropiperidine derivatives |
| PL2044043T5 (pl) | 2006-06-16 | 2022-05-02 | H. Lundbeck A/S | Bromowodorek 1-[2-(2,4-dimetylofenylosulfanylo)fenylo]piperazyny jako związek o połączonym działaniu wychwytu zwrotnego serotoniny i działaniu na 5-ht3 i 5-ht1a do leczenia upośledzenia funckji poznawczych |
| AU2007265467C1 (en) | 2006-06-28 | 2013-11-07 | Amgen Inc. | Glycine transporter-1 inhibitors |
| TW200848411A (en) * | 2007-03-20 | 2008-12-16 | Lundbeck & Co As H | Novel therapeutic uses of 1-[2-(2, 4-dimethylphenylsulfanyl)phenyl]-piperazine |
| MX2009014235A (es) | 2007-08-22 | 2010-04-27 | Abbott Gmbh & Co Kg | 4-bencilaminoquinolonas, composiciones farmaceuticas que las contiene y su uso. |
| TW200932233A (en) * | 2007-11-13 | 2009-08-01 | Lundbeck & Co As H | Therapeutic uses of compounds having combined SERT, 5-HT3 and 5-HT1a activity |
| JP2011506441A (ja) * | 2007-12-12 | 2011-03-03 | アムジエン・インコーポレーテツド | グリシン輸送体−1阻害薬 |
| EP2527328A1 (de) | 2008-04-01 | 2012-11-28 | Abbott GmbH & Co. KG | Tetrahydroisochinoline, pharmazeutische Zusammensetzungen damit und deren therapeutische Verwendung |
| AR075442A1 (es) | 2009-02-16 | 2011-03-30 | Abbott Gmbh & Co Kg | Derivados de aminotetralina, composiciones farmaceuticas que las contienen y sus usos en terapia |
| TW201038569A (en) | 2009-02-16 | 2010-11-01 | Abbott Gmbh & Co Kg | Heterocyclic compounds, pharmaceutical compositions containing them, and their use in therapy |
| EP2539706B1 (de) * | 2010-02-24 | 2015-03-04 | Research Triangle Institute | Arylpiperazin-opioid-rezeptor-antagonisten |
| US9051280B2 (en) | 2010-08-13 | 2015-06-09 | AbbVie Deutschland GmbH & Co. KG | Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US8877794B2 (en) | 2010-08-13 | 2014-11-04 | Abbott Laboratories | Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US8846743B2 (en) | 2010-08-13 | 2014-09-30 | Abbott Laboratories | Aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US8883839B2 (en) | 2010-08-13 | 2014-11-11 | Abbott Laboratories | Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US9045459B2 (en) | 2010-08-13 | 2015-06-02 | AbbVie Deutschland GmbH & Co. KG | Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US9309200B2 (en) | 2011-05-12 | 2016-04-12 | AbbVie Deutschland GmbH & Co. KG | Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US8853196B2 (en) | 2011-08-05 | 2014-10-07 | AbbVie Deutschland GmbH & Co. KG | Aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, pharmaceutical compositions containing them, and their use in therapy |
| CN104011028A (zh) | 2011-11-18 | 2014-08-27 | 艾伯维德国有限责任两合公司 | N-取代的氨基苯并环庚烯、氨基四氢化萘、氨基茚满和苯烷基胺衍生物、包含所述衍生物的药物组合物及其在治疗中的用途 |
| RS58683B1 (sr) * | 2012-01-03 | 2019-06-28 | H Lundbeck As | Postupak za proizvodnju 1-[2-(2,4-dimetil-fenilsulfanil)-fenil]-piperazina |
| US9365512B2 (en) | 2012-02-13 | 2016-06-14 | AbbVie Deutschland GmbH & Co. KG | Isoindoline derivatives, pharmaceutical compositions containing them, and their use in therapy |
| RU2652265C2 (ru) * | 2013-02-22 | 2018-04-27 | Х. Лундбекк А/С | Способ получения вортиоксетина |
| US9650334B2 (en) | 2013-03-15 | 2017-05-16 | Abbvie Inc. | Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US9656955B2 (en) | 2013-03-15 | 2017-05-23 | Abbvie Inc. | Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy |
| SG11201602935PA (en) | 2013-10-17 | 2016-05-30 | Abbvie Deutschland | Aminotetraline and aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy |
| WO2015055770A1 (en) | 2013-10-17 | 2015-04-23 | AbbVie Deutschland GmbH & Co. KG | Aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US9550754B2 (en) | 2014-09-11 | 2017-01-24 | AbbVie Deutschland GmbH & Co. KG | 4,5-dihydropyrazole derivatives, pharmaceutical compositions containing them, and their use in therapy |
| KR101753617B1 (ko) | 2016-05-10 | 2017-07-11 | 주식회사 뉴로벤티 | 피페라진-1-카복사미딘 또는 이의 약학적으로 허용가능한 염을 유효성분으로 포함하는 자폐 범주성 장애 예방 및 치료용 약학적 조성물 |
| WO2017215636A1 (zh) | 2016-06-16 | 2017-12-21 | 广东东阳光药业有限公司 | 二芳基硫醚哌嗪类化合物及其制备方法和用途 |
| CN106279071B (zh) * | 2016-08-10 | 2019-01-04 | 广东东阳光药业有限公司 | 苯基哌嗪衍生物及其使用方法和用途 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5730738A (en) | 1995-12-04 | 1998-03-24 | The Procter & Gamble Company | Absorbent article with angled band structural elastic-like film cuffs |
| JPH10152470A (ja) * | 1996-09-25 | 1998-06-09 | Yoshitomi Pharmaceut Ind Ltd | ピペラジン化合物 |
| WO1998017651A1 (en) * | 1996-10-21 | 1998-04-30 | Neurosearch A/S | 1-phenyl-benzimidazole compounds and their use as baga-a receptor modulators |
| BRPI0413587A (pt) * | 2003-08-21 | 2006-10-17 | Lundbeck & Co As H | usos de um composto e de um inibidor de glyt-1, composição farmacêutica, kit, e, método para o tratamento de doença |
-
2002
- 2002-12-16 AT AT02787451T patent/ATE359276T1/de not_active IP Right Cessation
- 2002-12-16 IL IL16196602A patent/IL161966A0/xx unknown
- 2002-12-16 ES ES02787451T patent/ES2280595T3/es not_active Expired - Lifetime
- 2002-12-16 DE DE60219521T patent/DE60219521T2/de not_active Expired - Fee Related
- 2002-12-16 HU HU0402320A patent/HUP0402320A2/hu unknown
- 2002-12-16 WO PCT/DK2002/000859 patent/WO2003053942A1/en not_active Ceased
- 2002-12-16 CA CA002467118A patent/CA2467118A1/en not_active Abandoned
- 2002-12-16 CN CNB028257022A patent/CN100457738C/zh not_active Expired - Fee Related
- 2002-12-16 AU AU2002351734A patent/AU2002351734A1/en not_active Abandoned
- 2002-12-16 JP JP2003554658A patent/JP2005513128A/ja active Pending
- 2002-12-16 EP EP02787451A patent/EP1458689B1/de not_active Expired - Lifetime
- 2002-12-16 MX MXPA04005989A patent/MXPA04005989A/es unknown
-
2004
- 2004-05-10 IS IS7258A patent/IS7258A/is unknown
- 2004-05-20 US US10/851,769 patent/US7067501B2/en not_active Expired - Fee Related
- 2004-07-07 NO NO20042885A patent/NO20042885L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20042885L (no) | 2004-07-07 |
| CN1606548A (zh) | 2005-04-13 |
| US20050171061A1 (en) | 2005-08-04 |
| MXPA04005989A (es) | 2004-09-27 |
| ATE359276T1 (de) | 2007-05-15 |
| AU2002351734A1 (en) | 2003-07-09 |
| EP1458689A1 (de) | 2004-09-22 |
| DE60219521T2 (de) | 2007-08-16 |
| US7067501B2 (en) | 2006-06-27 |
| DE60219521D1 (de) | 2007-05-24 |
| WO2003053942A1 (en) | 2003-07-03 |
| HK1076807A1 (zh) | 2006-01-27 |
| CA2467118A1 (en) | 2003-07-03 |
| HUP0402320A2 (hu) | 2005-03-29 |
| ES2280595T3 (es) | 2007-09-16 |
| IS7258A (is) | 2004-05-10 |
| EP1458689B1 (de) | 2007-04-11 |
| JP2005513128A (ja) | 2005-05-12 |
| CN100457738C (zh) | 2009-02-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL161966A0 (en) | Aryloxyphenyl and arylsulfanylphenyl | |
| PL372926A1 (en) | Piperidine-pyridazones and phthalazones as pde4 inhibitors | |
| PL369530A1 (en) | Chemical compounds | |
| IL163777A0 (en) | Kinase inhibitors | |
| CY1109006T1 (el) | Παραγωγα πουρινης ως αναστολεις κινασης | |
| ZA200704910B (en) | Pyrrolidine inhibitors of IAP | |
| TW200640924A (en) | VEGF-R2 inhibitors and methods | |
| GB0130341D0 (en) | Compounds | |
| MXPA04003886A (es) | Tiofen- y tiazolsulfonamidas como agentes antineoplasticos. | |
| CY1106132T1 (el) | Παραγωγα πιπepιδινης ως αναστολεις καναλιου καλιου | |
| GEP20074215B (en) | Novel method for the industrial synthesis of strontium ranelate and the hydrates thereof | |
| MY133969A (en) | Indoloquinazolinones | |
| MXPA04006266A (es) | Pirimidotriazinas como inhibidores de fosfatasa. | |
| AU2003290592A1 (en) | Antitumor benzoylsulfonamides | |
| SE0103710D0 (sv) | Compounds | |
| TW200613308A (en) | Cyclobutanetetracarboxylate compound and preparation method thereof | |
| DE60204701D1 (de) | Tricyclische imidazopyridine | |
| UA85505C2 (en) | Kinase inhibitors | |
| MY128164A (en) | Compounds | |
| SI1377574T1 (de) | ||
| MXPA06003345A (es) | Derivados de aminopiridina como inhibidores de la no-sintasa inducible. | |
| MXPA06000372A (es) | Compuestos de silicio y su uso. | |
| NO20033921L (no) | Inhibitor av monoaminopptak | |
| AU2003236701A8 (en) | Guanidino phenylalanin compounds used as urokinase inhibitors | |
| GB0226550D0 (en) | Organic compounds |