IL162949A0 - Construction of west nile virus and dengue virus chimeras for use in a virus vaccine to prevent disease caused by west nile virus - Google Patents

Construction of west nile virus and dengue virus chimeras for use in a virus vaccine to prevent disease caused by west nile virus

Info

Publication number: IL162949A0
Authority: IL; Israel
Prior art keywords: virus; west nile; construction; chimeras; nile virus
Prior art date: 2002-01-10

Application number

IL16294903A

Other languages

English (en)

Original Assignee

Us Gov Health & Human Serv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-01-10

Filing date

2003-01-09

Publication date

2005-11-20

2003-01-09 Application filed by Us Gov Health & Human Serv filed Critical Us Gov Health & Human Serv

2005-11-20 Publication of IL162949A0 publication Critical patent/IL162949A0/xx

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24141—Use of virus, viral particle or viral elements as a vector
- C12N2770/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24161—Methods of inactivation or attenuation
- C12N2770/24162—Methods of inactivation or attenuation by genetic engineering
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Virology (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Immunology (AREA)
Microbiology (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Analytical Chemistry (AREA)
Physics & Mathematics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Mycology (AREA)
Epidemiology (AREA)
Plant Pathology (AREA)
Gastroenterology & Hepatology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IL16294903A 2002-01-10 2003-01-09 Construction of west nile virus and dengue virus chimeras for use in a virus vaccine to prevent disease caused by west nile virus IL162949A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US34728102P	2002-01-10	2002-01-10
PCT/US2003/000594 WO2003059384A1 (fr)	2002-01-10	2003-01-09	Production de chimeres du virus de la dengue et du virus du nil occidental en vue de leur utilisation dans un vaccin contre le virus vivant a titre de prevention de la maladie provoquee par le virus du nil occidental

Publications (1)

Publication Number	Publication Date
IL162949A0 true IL162949A0 (en)	2005-11-20

Family

ID=23363073

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
IL16294903A IL162949A0 (en)	2002-01-10	2003-01-09	Construction of west nile virus and dengue virus chimeras for use in a virus vaccine to prevent disease caused by west nile virus
IL162949A IL162949A (en)	2002-01-10	2004-07-11	West nile virus and dengue type 4 virus nucleic acid chimera for use in a viral vaccine to prevent disease caused by west nile virus
IL209342A IL209342A (en)	2002-01-10	2010-11-16	Nucleic acid chimera composed of West Nile virus and dengue fever virus, preparations containing them and their uses

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
IL162949A IL162949A (en)	2002-01-10	2004-07-11	West nile virus and dengue type 4 virus nucleic acid chimera for use in a viral vaccine to prevent disease caused by west nile virus
IL209342A IL209342A (en)	2002-01-10	2010-11-16	Nucleic acid chimera composed of West Nile virus and dengue fever virus, preparations containing them and their uses

Country Status (8)

Country	Link
US (5)	US8778671B2 (fr)
EP (3)	EP2949754A1 (fr)
JP (4)	JP4580650B2 (fr)
AU (3)	AU2003216046B2 (fr)
CA (2)	CA2472468C (fr)
DK (1)	DK2339011T3 (fr)
IL (3)	IL162949A0 (fr)
WO (1)	WO2003059384A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2472468C (fr)	2002-01-10	2015-11-24	Alexander G. Pletnev	Production de chimeres du virus de la dengue et du virus du nil occidental en vue de leur utilisation dans un vaccin contre le virus vivant a titre de prevention de la maladie provoquee par le virus du nil occidental
FR2870126B1 (fr)	2004-05-17	2009-07-17	Pasteur Institut	Vecteur lentiviral recombinant d'expression d'une proteine de flaviviridae et ses applications comme vaccin
US7851194B2 (en)	2004-06-14	2010-12-14	The United States Of America As Represented By The Department Of Health And Human Services	West Nile viruses with mutations in the 3′ terminal stem and loop secondary structure for use as live virus vaccines
US8124398B2 (en)	2005-04-24	2012-02-28	Sanofi Pasteur Biologics Co.	Recombinant flavivirus vaccines
FR2890859B1 (fr)	2005-09-21	2012-12-21	Oreal	Oligonucleotide d'arn double brin inhibant l'expression de la tyrosinase
US20100316670A1 (en) *	2007-06-14	2010-12-16	Blaney Joseph E	Chimeric sle/dengue type 4 antigenic viruses
US8715689B2 (en)	2008-04-30	2014-05-06	The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention	Chimeric west nile/dengue viruses
WO2012125125A1 (fr) *	2011-03-15	2012-09-20	Agency For Science, Technology And Research	Acides nucléiques et procédés de détermination d'évolution de la dengue
BR112018068342A2 (pt)	2016-03-11	2019-01-15	Univ Johns Hopkins	vacina de vírus zika vivo atenuado
WO2018129160A1 (fr)	2017-01-06	2018-07-12	The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Vaccins à flavivirus vivants atténués et leurs méthodes d'utilisation et de fabrication

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0872553B1 (fr) *	1991-09-19	2000-11-15	THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the Secretary of the Department of HEALTH AND HUMAN SERVICES	Flavivirus chimériques et/ou flavivirus à croissance limitée
US6537557B1 (en) *	1999-03-26	2003-03-25	The United States Of America As Represented By The Secretary Of The Army	Attenuated dengue-4 virus vaccine
DK2278012T3 (en) *	2000-02-16	2015-12-07	Us Government	Immunogenic dengue 2 virus chimeras
CA2472468C (fr) *	2002-01-10	2015-11-24	Alexander G. Pletnev	Production de chimeres du virus de la dengue et du virus du nil occidental en vue de leur utilisation dans un vaccin contre le virus vivant a titre de prevention de la maladie provoquee par le virus du nil occidental
DK2054428T3 (da) *	2006-08-15	2013-08-26	Government Of The U S A As Repr By The Secretary Dept Of Health & Human Services The Nat Inst Of Hea	Udvikling af bestanddele til denque-virus-vaccine

2003
- 2003-01-09 CA CA2472468A patent/CA2472468C/fr not_active Expired - Lifetime
- 2003-01-09 CA CA2903126A patent/CA2903126C/fr not_active Expired - Lifetime
- 2003-01-09 WO PCT/US2003/000594 patent/WO2003059384A1/fr not_active Ceased
- 2003-01-09 EP EP15163537.2A patent/EP2949754A1/fr not_active Withdrawn
- 2003-01-09 IL IL16294903A patent/IL162949A0/xx unknown
- 2003-01-09 EP EP03729602A patent/EP1467754A4/fr not_active Ceased
- 2003-01-09 AU AU2003216046A patent/AU2003216046B2/en not_active Expired
- 2003-01-09 DK DK11000126.0T patent/DK2339011T3/en active
- 2003-01-09 JP JP2003559545A patent/JP4580650B2/ja not_active Expired - Lifetime
- 2003-01-09 EP EP11000126.0A patent/EP2339011B1/fr not_active Expired - Lifetime
2004
- 2004-06-18 US US10/871,775 patent/US8778671B2/en not_active Expired - Fee Related
- 2004-07-11 IL IL162949A patent/IL162949A/en active IP Right Grant
2008
- 2008-07-31 AU AU2008203442A patent/AU2008203442B2/en not_active Expired
2009
- 2009-03-11 JP JP2009058277A patent/JP2009153520A/ja active Pending
2010
- 2010-11-16 IL IL209342A patent/IL209342A/en active IP Right Grant
2011
- 2011-10-12 JP JP2011225056A patent/JP2012040014A/ja active Pending
- 2011-11-10 AU AU2011250694A patent/AU2011250694B8/en not_active Expired
2013
- 2013-08-01 JP JP2013160104A patent/JP2013247958A/ja active Pending
2014
- 2014-06-16 US US14/305,572 patent/US10058602B2/en not_active Expired - Lifetime
2018
- 2018-07-02 US US16/025,624 patent/US10456461B2/en not_active Expired - Fee Related
2019
- 2019-10-08 US US16/596,175 patent/US10869920B2/en not_active Expired - Fee Related
2020
- 2020-11-19 US US16/952,864 patent/US11400150B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP2949754A1 (fr)	2015-12-02
CA2472468A1 (fr)	2003-07-24
EP1467754A1 (fr)	2004-10-20
EP2339011B1 (fr)	2015-04-15
AU2008203442B2 (en)	2011-09-08
AU2003216046B2 (en)	2008-05-01
AU2011250694A8 (en)	2013-09-12
JP4580650B2 (ja)	2010-11-17
AU2011250694B8 (en)	2013-09-12
CA2903126C (fr)	2020-03-24
JP2012040014A (ja)	2012-03-01
AU2011250694A1 (en)	2011-12-01
EP2339011A1 (fr)	2011-06-29
EP1467754A4 (fr)	2009-09-23
US8778671B2 (en)	2014-07-15
US10456461B2 (en)	2019-10-29
US20140294892A1 (en)	2014-10-02
IL162949A (en)	2011-11-30
US10058602B2 (en)	2018-08-28
IL209342A (en)	2015-10-29
JP2005521384A (ja)	2005-07-21
JP2009153520A (ja)	2009-07-16
US20050100886A1 (en)	2005-05-12
US11400150B2 (en)	2022-08-02
AU2011250694B2 (en)	2013-05-16
WO2003059384A1 (fr)	2003-07-24
IL209342A0 (en)	2011-01-31
US20180369358A1 (en)	2018-12-27
JP2013247958A (ja)	2013-12-12
US20200030435A1 (en)	2020-01-30
AU2003216046A1 (en)	2003-07-30
DK2339011T3 (en)	2015-07-06
AU2008203442A1 (en)	2008-08-21
CA2472468C (fr)	2015-11-24
US10869920B2 (en)	2020-12-22
CA2903126A1 (fr)	2003-07-24
US20210069317A1 (en)	2021-03-11

Publication	Publication Date	Title
IL209342A0 (en)	2011-01-31	Construction of west nile virus and dengue virus chimeras for use in a virus vaccine to prevent disease caused by west nile virus
FR23C1005I1 (fr)	2023-03-24	Vaccins contre les flavivirus
EP1542717A4 (fr)	2005-12-14	Amelioration concernant les vaccins ou en rapport avec ceux-ci
EP1553966A4 (fr)	2008-04-16	Polypeptides du papillomavirus humain et compositions immunogenes
NO2017005I1 (no)	2017-01-20	Human pappilomavirus vaksine [type 6, 11, 16, 18, 31, 33, 45, 52, 58]
CR8706A (es)	2009-01-16	Mimeticuerpos de peptido-1 similar a glucagon de humano, composiciones, metodos, usos
IL175472A0 (en)	2006-09-05	Glucoimidazole and polyhydroxycyclohexenyl amine derivatives to treat gaucher disease
IS8069A (is)	2005-10-12	Aðferðir og lyfjasamsetningar til að ná áreiðanlega ásættanlegum testósterónstyrk
ATE421875T1 (de)	2009-02-15	Superfeine salmeterol zubereitung
PL1767221T3 (pl)	2014-02-28	Wytwarzanie i zastosowanie biwalentnej szczepionki przeciwko uzależnieniu od morfiny-heroiny
GB0419124D0 (en)	2004-09-29	Methods and compositions relating to Alzheimer's disease
EP1583557A4 (fr)	2007-11-14	Compositions vaccinales et procedes
EP1539965A4 (fr)	2006-02-15	Expression de igf-1 humain dans des plastes transgeniques
GB2388916B (en)	2004-12-01	Improvements in and relating to piezo-electric elements
GB0220481D0 (en)	2002-10-09	Improvements in and relating to computer action game controller supports
GB2392699B (en)	2006-01-11	Improvements in or relating to posts
GB2387351B (en)	2005-05-11	Improvements in and relating to fire barriers
GB2409518B (en)	2006-12-27	Improvements in and relating to investigations
GB0308399D0 (en)	2003-05-21	Improvements in and relating to kettles
GB2411357B (en)	2007-06-06	Vaccine for cold-water disease in fish
GB2405878B (en)	2005-10-19	Improvements in and relating to weatherboarding
ITTO20040255A1 (it)	2004-07-23	Procedimento per realizzare strutture contenenti uretano e strutture cosi' realizzate
AU2003291234A8 (en)	2004-06-03	Compositions and methods for enhancing disease resistance in fish
GB0207596D0 (en)	2002-05-15	Improvements in or relating to patient support structures and their use
IL178420A0 (en)	2007-02-11	Formulations and methods to prepare inhalable buffered methacholine chloride solutions