CR8706A - Mimeticuerpos de peptido-1 similar a glucagon de humano, composiciones, metodos, usos - Google Patents
Mimeticuerpos de peptido-1 similar a glucagon de humano, composiciones, metodos, usosInfo
- Publication number
- CR8706A CR8706A CR8706A CR8706A CR8706A CR 8706 A CR8706 A CR 8706A CR 8706 A CR8706 A CR 8706A CR 8706 A CR8706 A CR 8706A CR 8706 A CR8706 A CR 8706A
- Authority
- CR
- Costa Rica
- Prior art keywords
- mimeticbodies
- peptide
- compositions
- methods
- similar
- Prior art date
Links
- 101500028775 Homo sapiens Glucagon Proteins 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Toxicology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Cardiology (AREA)
- Microbiology (AREA)
- Hospice & Palliative Care (AREA)
- Physics & Mathematics (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Plant Pathology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55798304P | 2004-03-31 | 2004-03-31 | |
| US61298104P | 2004-09-24 | 2004-09-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR8706A true CR8706A (es) | 2009-01-16 |
Family
ID=35125618
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR8706A CR8706A (es) | 2004-03-31 | 2006-10-25 | Mimeticuerpos de peptido-1 similar a glucagon de humano, composiciones, metodos, usos |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20070135338A1 (es) |
| EP (1) | EP1750754A4 (es) |
| JP (1) | JP2008537873A (es) |
| KR (1) | KR20070004078A (es) |
| AR (1) | AR049014A1 (es) |
| AU (1) | AU2005231359A1 (es) |
| BR (1) | BRPI0509528A (es) |
| CA (1) | CA2563379A1 (es) |
| CR (1) | CR8706A (es) |
| EA (2) | EA011583B1 (es) |
| IL (1) | IL178432A0 (es) |
| MX (1) | MXPA06011425A (es) |
| NO (1) | NO20064953L (es) |
| SG (1) | SG151315A1 (es) |
| TW (1) | TW200602491A (es) |
| WO (1) | WO2005097175A2 (es) |
| ZA (1) | ZA200709266B (es) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006000567A2 (en) * | 2004-06-28 | 2006-01-05 | Novo Nordisk A/S | Use of glp-1 receptor agonists and / or dpp-iv inhibitors in combination with proton pump inhibitors and ppar agonists for the preparation of a medicament for the treatment of diabetes type i i and impaired pancreatic beta-cell function |
| US7910101B2 (en) | 2004-10-25 | 2011-03-22 | Centocor, Inc. | Melanocortin receptor binding mimetibodies, compositions, methods and uses |
| RS51789B (sr) * | 2004-10-25 | 2011-12-31 | Centocor Ortho Biotech Inc. | Mimetička tela koja vezuju receptore melanokortina, smese, postupci i upotrebe |
| US20070128193A1 (en) * | 2004-12-22 | 2007-06-07 | O'neil Karyn T | GLP-1 agonists, compositions, methods and uses |
| TW200643033A (en) * | 2005-03-08 | 2006-12-16 | Chugai Pharmaceutical Co Ltd | Conjugate of water-soluble modified hyaluronic acid and glp-1 analogue |
| AU2005339797A1 (en) * | 2005-03-28 | 2007-07-19 | Centocor, Inc. | Human GLP-1 mimetibodies, compositions, methods and uses |
| US9284375B2 (en) | 2005-04-15 | 2016-03-15 | Macrogenics, Inc. | Covalent diabodies and uses thereof |
| US9963510B2 (en) * | 2005-04-15 | 2018-05-08 | Macrogenics, Inc. | Covalent diabodies and uses thereof |
| ES2971647T3 (es) | 2005-04-15 | 2024-06-06 | Macrogenics Inc | Diacuerpos covalentes y usos de los mismos |
| US11254748B2 (en) | 2005-04-15 | 2022-02-22 | Macrogenics, Inc. | Covalent diabodies and uses thereof |
| US8658174B2 (en) | 2005-07-27 | 2014-02-25 | Qinghua Wang | GLP/1/exendin 4 IgG Fc fusion constructs for treatment of diabetes |
| DE602005017628D1 (de) | 2005-09-22 | 2009-12-24 | Biocompatibles Uk Ltd | Fusionspolypeptide vom glp-1 (glucagon-like peptide-1) mit erhöhten peptidaseresistenz |
| EA200801174A1 (ru) * | 2005-10-24 | 2009-02-27 | Сентокор, Инк. | Антитела-миметики glp-2, полипептиды, композиции, способы и применения |
| EP1968645A4 (en) * | 2005-12-22 | 2009-11-04 | Centocor Ortho Biotech Inc | HUMAN GLP-1 MIMETIC BODIES AND COMPOSITIONS FOR THE TREATMENT OF ADIPOSITAS AND RELATED DISEASES, METHODS AND APPLICATIONS |
| US20100034819A1 (en) * | 2006-03-31 | 2010-02-11 | Centocor Inc. | Human epo mimetic hinge core mimetibodies, compositions, methods and uses for preventing or treating glucose intolerance related conditions on renal disease associated anemia |
| EP1854455B1 (en) | 2006-05-10 | 2009-10-07 | Biocompatibles UK Limited | Spherical microcapsules comprising GLP-1 peptides, their production and use |
| WO2008011446A2 (en) | 2006-07-18 | 2008-01-24 | Centocor, Inc. | Human glp-1 mimetibodies, compositions, methods and uses |
| JP5290177B2 (ja) * | 2006-08-31 | 2013-09-18 | セントカー・インコーポレーテツド | Glp−2ミメティボディ、ポリペプチド、組成物、方法および用途 |
| AR064623A1 (es) * | 2006-12-21 | 2009-04-15 | Centocor Inc | Uso de agonistas del receptor de glp -1 de accion prolongada para mejorar la sensibilidad a la insulina y los perfiles lipidicos |
| EP1975176A1 (en) * | 2007-03-27 | 2008-10-01 | Biocompatibles UK Limited | Novel glp-1 fusion peptides, their production and use |
| JP2011503000A (ja) * | 2007-11-02 | 2011-01-27 | セントコア・オーソ・バイオテツク・インコーポレーテツド | 半合成GLP−1ペプチド−Fc融合コンストラクト、その方法及び使用 |
| ES2589912T3 (es) | 2008-04-02 | 2016-11-17 | Macrogenics, Inc. | Anticuerpos específicos para el complejo BCR y procedimientos de uso de los mismos |
| US20110081347A1 (en) * | 2008-06-04 | 2011-04-07 | Macrogenics, Inc. | Antibodies with Altered Binding to FcRn and Methods of Using Same |
| CA2731236A1 (en) * | 2008-07-21 | 2010-01-28 | Transpharma Medical Ltd. | Transdermal system for extended delivery of incretins and incretin mimetic peptides |
| RS59913B1 (sr) | 2008-10-17 | 2020-03-31 | Sanofi Aventis Deutschland | Kombinacija insulina i glp-1-agonista |
| DK2786762T3 (da) * | 2008-12-19 | 2019-05-06 | Macrogenics Inc | Kovalente diabodies og anvendelser deraf |
| US20100291160A1 (en) * | 2009-05-13 | 2010-11-18 | Carver David R | Pharmaceutical system for trans-membrane delivery |
| CN102596175A (zh) | 2009-07-06 | 2012-07-18 | 赛诺菲-安万特德国有限公司 | 含有甲硫氨酸的水性胰岛素制备物 |
| JP5898082B2 (ja) | 2009-10-07 | 2016-04-06 | マクロジェニクス,インコーポレーテッド | フコシル化程度の変更により改良されたエフェクター機能を示すFc領域含有ポリペプチドおよびその使用法 |
| WO2011044589A2 (en) * | 2009-10-09 | 2011-04-14 | Board Of Regents, The University Of Texas System | Photokinetic ocular drug delivery methods and apparatus |
| ES2622102T3 (es) | 2009-10-29 | 2017-07-05 | Janssen Biotech, Inc. | Variantes de anticuerpo de glicosilación |
| PT3345593T (pt) | 2009-11-13 | 2023-11-27 | Sanofi Aventis Deutschland | Composição farmacêutica compreendendo despro36exendina- 4(1-39)-lys6-nh2 e metionina |
| MY180661A (en) | 2009-11-13 | 2020-12-04 | Sanofi Aventis Deutschland | Pharmaceutical composition comprising a glp-1 agonist, an insulin and methionine |
| EP2542256B1 (en) | 2010-03-04 | 2019-05-22 | MacroGenics, Inc. | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
| PH12012501751A1 (en) | 2010-03-04 | 2012-11-12 | Macrogenics Inc | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
| AU2011202239C1 (en) | 2010-05-19 | 2017-03-16 | Sanofi | Long-acting formulations of insulins |
| AU2011286024B2 (en) | 2010-08-02 | 2014-08-07 | Macrogenics, Inc. | Covalent diabodies and uses thereof |
| PL2611458T3 (pl) | 2010-08-30 | 2017-02-28 | Sanofi-Aventis Deutschland Gmbh | Zastosowanie AVE0010 do produkcji leku do leczenia cukrzycy typu 2 |
| US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
| BR112013029892A2 (pt) | 2011-05-21 | 2016-12-20 | Macrogenics Inc | polipeptídeo, molécula de ligação a antígeno, diacorpo e uso de uma porção polipeptídica de uma proteína de ligação a soro desimunizada |
| AR087693A1 (es) | 2011-08-29 | 2014-04-09 | Sanofi Aventis Deutschland | Combinacion farmaceutica para uso en el control glucemico en pacientes con diabetes de tipo 2 |
| TWI559929B (en) | 2011-09-01 | 2016-12-01 | Sanofi Aventis Deutschland | Pharmaceutical composition for use in the treatment of a neurodegenerative disease |
| JP6126097B2 (ja) | 2011-09-06 | 2017-05-10 | ノヴォ ノルディスク アー/エス | Glp−1誘導体 |
| US9487587B2 (en) | 2013-03-05 | 2016-11-08 | Macrogenics, Inc. | Bispecific molecules that are immunoreactive with immune effector cells of a companion animal that express an activating receptor and cells that express B7-H3 and uses thereof |
| SMT202100464T1 (it) | 2013-03-14 | 2021-11-12 | Macrogenics Inc | Molecole bispecifiche che sono immunoreattive con cellule effettrici immunitarie che esprimono un recettore di attivazione |
| UA117480C2 (uk) | 2013-04-03 | 2018-08-10 | Санофі | Лікування цукрового діабету за допомогою складу інсуліну тривалої дії |
| US11384149B2 (en) | 2013-08-09 | 2022-07-12 | Macrogenics, Inc. | Bi-specific monovalent Fc diabodies that are capable of binding CD32B and CD79b and uses thereof |
| UA116479C2 (uk) | 2013-08-09 | 2018-03-26 | Макродженікс, Інк. | БІСПЕЦИФІЧНЕ МОНОВАЛЕНТНЕ Fc-ДІАТІЛО, ЯКЕ ОДНОЧАСНО ЗВ'ЯЗУЄ CD32B I CD79b, ТА ЙОГО ЗАСТОСУВАННЯ |
| CN104371019B (zh) * | 2013-08-13 | 2019-09-10 | 鸿运华宁(杭州)生物医药有限公司 | 一种能与glp-1r特异性结合的抗体及其与glp-1的融合蛋白质 |
| EP2840091A1 (en) | 2013-08-23 | 2015-02-25 | MacroGenics, Inc. | Bi-specific diabodies that are capable of binding gpA33 and CD3 and uses thereof |
| EP2839842A1 (en) | 2013-08-23 | 2015-02-25 | MacroGenics, Inc. | Bi-specific monovalent diabodies that are capable of binding CD123 and CD3 and uses thereof |
| CN111879948A (zh) | 2013-10-17 | 2020-11-03 | 综合医院公司 | 鉴定响应于用于自身免疫性疾病的治疗的受试者的方法以及用于治疗该疾病的组合物 |
| MX386297B (es) | 2014-09-29 | 2025-03-18 | Univ Duke | Moleculas biespecificas que comprenden un brazo orientado a la envoltura vih-1. |
| EP3229828B1 (en) | 2014-12-12 | 2023-04-05 | Sanofi-Aventis Deutschland GmbH | Insulin glargine/lixisenatide fixed ratio formulation |
| TWI748945B (zh) | 2015-03-13 | 2021-12-11 | 德商賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患治療 |
| TW201705975A (zh) | 2015-03-18 | 2017-02-16 | 賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患之治療 |
| GEP20227398B (en) | 2016-04-15 | 2022-07-25 | Macrogenics Inc | Novel b7-h3 binding molecules, antibody drug conjugates thereof and usage thereof |
| TWI829687B (zh) | 2018-05-07 | 2024-01-21 | 丹麥商諾佛 儂迪克股份有限公司 | 包含glp-1促效劑與n-(8-(2-羥基苯甲醯基)胺基)辛酸之鹽的固體組成物 |
| US20230149478A1 (en) * | 2020-03-25 | 2023-05-18 | The General Hospital Corporation | Compositions and methods for diabetes treatment |
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2005
- 2005-03-28 US US11/091,181 patent/US20070135338A1/en not_active Abandoned
- 2005-03-28 EP EP05730437A patent/EP1750754A4/en not_active Withdrawn
- 2005-03-28 SG SG200902141-1A patent/SG151315A1/en unknown
- 2005-03-28 WO PCT/US2005/010456 patent/WO2005097175A2/en not_active Ceased
- 2005-03-28 EA EA200601603A patent/EA011583B1/ru not_active IP Right Cessation
- 2005-03-28 JP JP2007506454A patent/JP2008537873A/ja active Pending
- 2005-03-28 BR BRPI0509528-0A patent/BRPI0509528A/pt not_active Application Discontinuation
- 2005-03-28 CA CA002563379A patent/CA2563379A1/en not_active Abandoned
- 2005-03-28 MX MXPA06011425A patent/MXPA06011425A/es not_active Application Discontinuation
- 2005-03-28 KR KR1020067022887A patent/KR20070004078A/ko not_active Ceased
- 2005-03-28 AU AU2005231359A patent/AU2005231359A1/en not_active Abandoned
- 2005-03-30 TW TW094109910A patent/TW200602491A/zh unknown
- 2005-03-31 AR ARP050101276A patent/AR049014A1/es unknown
- 2005-12-22 EA EA200702093A patent/EA200702093A1/ru unknown
-
2006
- 2006-10-03 IL IL178432A patent/IL178432A0/en unknown
- 2006-10-25 CR CR8706A patent/CR8706A/es not_active Application Discontinuation
- 2006-10-30 NO NO20064953A patent/NO20064953L/no not_active Application Discontinuation
-
2007
- 2007-10-26 ZA ZA200709266A patent/ZA200709266B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20070004078A (ko) | 2007-01-05 |
| EP1750754A2 (en) | 2007-02-14 |
| JP2008537873A (ja) | 2008-10-02 |
| EA200601603A1 (ru) | 2007-08-31 |
| IL178432A0 (en) | 2007-02-11 |
| EP1750754A4 (en) | 2010-09-22 |
| WO2005097175A2 (en) | 2005-10-20 |
| US20070135338A1 (en) | 2007-06-14 |
| CA2563379A1 (en) | 2005-10-20 |
| NO20064953L (no) | 2006-12-18 |
| AR049014A1 (es) | 2006-06-21 |
| EA011583B1 (ru) | 2009-04-28 |
| MXPA06011425A (es) | 2007-03-12 |
| TW200602491A (en) | 2006-01-16 |
| ZA200709266B (en) | 2009-05-27 |
| WO2005097175A3 (en) | 2009-11-19 |
| EA200702093A1 (ru) | 2009-06-30 |
| BRPI0509528A (pt) | 2007-08-07 |
| AU2005231359A1 (en) | 2005-10-20 |
| SG151315A1 (en) | 2009-04-30 |
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