IL165671A0 - Ortho-substituted benzoic acid derivatives for thetreatment of insulin resistance - Google Patents

Ortho-substituted benzoic acid derivatives for thetreatment of insulin resistance

Info

Publication number: IL165671A0
Authority: IL; Israel
Prior art keywords: thetreatment; ortho; benzoic acid; acid derivatives; insulin resistance
Prior art date: 2002-06-20

Application number

IL16567104A

Other languages

English (en)

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-06-20

Filing date

2004-12-09

Publication date

2006-01-15

2002-06-20 Priority claimed from SE0201935A external-priority patent/SE0201935D0/xx

2002-12-20 Priority claimed from SE0203826A external-priority patent/SE0203826D0/xx

2004-12-09 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2006-01-15 Publication of IL165671A0 publication Critical patent/IL165671A0/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Diabetes (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Obesity (AREA)
Hematology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Endocrinology (AREA)
Child & Adolescent Psychology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Emergency Medicine (AREA)
Epidemiology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)

IL16567104A 2002-06-20 2004-12-09 Ortho-substituted benzoic acid derivatives for thetreatment of insulin resistance IL165671A0 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
SE0201935A SE0201935D0 (sv)	2002-06-20	2002-06-20	Therapeutic agents
SE0203826A SE0203826D0 (sv)	2002-12-20	2002-12-20	Therapeutic agents
PCT/GB2003/002584 WO2004000790A1 (en)	2002-06-20	2003-06-17	Ortho-substituted benzoic acid derivatives for the treatment of insulin resistance

Publications (1)

Publication Number	Publication Date
IL165671A0 true IL165671A0 (en)	2006-01-15

Family

ID=30002442

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL16567104A IL165671A0 (en)	2002-06-20	2004-12-09	Ortho-substituted benzoic acid derivatives for thetreatment of insulin resistance

Country Status (22)

Country	Link
US (1)	US7355069B2 (pl)
EP (1)	EP1517883B8 (pl)
JP (2)	JP3782818B2 (pl)
KR (1)	KR20050014013A (pl)
CN (1)	CN1319938C (pl)
AR (1)	AR039713A1 (pl)
AT (1)	ATE386013T1 (pl)
AU (1)	AU2003240099B2 (pl)
BR (1)	BR0311932A (pl)
CA (1)	CA2489834C (pl)
DE (1)	DE60319084T2 (pl)
DK (1)	DK1517883T3 (pl)
ES (1)	ES2299702T3 (pl)
IL (1)	IL165671A0 (pl)
IS (1)	IS7627A (pl)
MX (1)	MXPA04012686A (pl)
NO (1)	NO20045353L (pl)
PL (1)	PL375074A1 (pl)
PT (1)	PT1517883E (pl)
RU (1)	RU2004137094A (pl)
TW (1)	TWI282784B (pl)
WO (1)	WO2004000790A1 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6262118B1 (en) *	1999-06-04	2001-07-17	Metabolex, Inc.	Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes and hyperlipidemia
US7576131B2 (en)	1999-06-04	2009-08-18	Metabolex, Inc.	Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia
SE0104333D0 (sv)	2001-12-19	2001-12-19	Astrazeneca Ab	Therapeutic agents
FR2875805B1 (fr) *	2004-09-27	2006-12-29	Genfit S A	Composes derives de n-(benzyl) phenylacetamide substitues, preparation et utilisations
GB0522433D0 (en) *	2005-11-03	2005-12-14	Astrazeneca Ab	Therapeutic agents
GB0522431D0 (en) *	2005-11-03	2005-12-14	Astrazeneca Ab	Chemical process

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK148576A (da)	1975-04-18	1976-10-19	Boehringer Mannheim Gmbh	Fenylalkankarbonsyrederivater og fremgangsmade til deres fremstilling
DE19615263A1 (de) *	1996-04-18	1997-10-23	Bayer Ag	Benzyloxy-substituierte Phenylglycinolamide
IL135673A0 (en)	1997-10-17	2001-05-20	Aventis Pharm Prod Inc	Therapeutic uses of quinoline derivatives
NZ503809A (en)	1997-12-19	2002-04-26	Schering Ag	Ortho-anthranilamide derivatives as anti-coagulants
SE9801992D0 (sv)	1998-06-04	1998-06-04	Astra Ab	New 3-aryl-2-hydroxypropionic acid derivative I
GB9822473D0 (en)	1998-10-16	1998-12-09	Glaxo Group Ltd	Chemical compounds
IL145922A0 (en)	1999-04-28	2002-07-25	Aventis Pharma Gmbh	Di-aryl acid derivatives as ppar receptor ligands
PT1177176E (pt)	1999-04-28	2006-08-31	Aventis Pharma Gmbh	Derivados de acidos triarilicos como ligandos de receptores ppar.
JP4618845B2 (ja) *	1999-06-09	2011-01-26	杏林製薬株式会社	ヒトペルオキシゾーム増殖薬活性化受容体（ＰＰＡＲ）αアゴニストとしての置換フェニルプロピオン酸誘導体
GB9919411D0 (en)	1999-08-18	1999-10-20	Zeneca Ltd	Chemical compounds
SE0000772D0 (sv)	2000-03-08	2000-03-08	Astrazeneca Ab	Chemical compounds
US6509374B2 (en)	2000-04-17	2003-01-21	Novo Nordisk A/S	Compounds, their preparation and use
SE0003766D0 (sv)	2000-10-18	2000-10-18	Astrazeneca Ab	Novel formulation
EG26979A (en)	2000-12-21	2015-03-01	Astrazeneca Ab	Chemical compounds
GB0116955D0 (en)	2001-07-11	2001-09-05	Syngenta Ltd	Weed control process
GB0121337D0 (en)	2001-09-04	2001-10-24	Astrazeneca Ab	Chemical compounds
GB0121622D0 (en)	2001-09-07	2001-10-31	Astrazeneca Ab	Chemical compounds
GB0121621D0 (en)	2001-09-07	2001-10-31	Astrazeneca Ab	Chemical compounds
PL216023B1 (pl)	2001-09-08	2014-02-28	Astrazeneca Ab	Pochodna benzotiadiazepiny, kompozycja farmaceutyczna zawierajaca pochodna benzotiadiazepiny oraz zastosowania pochodnej benzotiadiazepiny
SE0104333D0 (sv)	2001-12-19	2001-12-19	Astrazeneca Ab	Therapeutic agents
SE0104334D0 (sv)	2001-12-19	2001-12-19	Astrazeneca Ab	Therapeutic agents
GB0229931D0 (en)	2002-12-21	2003-01-29	Astrazeneca Ab	Therapeutic agents
GB0209467D0 (en)	2002-04-25	2002-06-05	Astrazeneca Ab	Chemical compounds
GB0213669D0 (en)	2002-06-14	2002-07-24	Astrazeneca Ab	Chemical compounds
SE0201936D0 (sv)	2002-06-20	2002-06-20	Astrazeneca Ab	Therapeutic agents
SE0201937D0 (sv)	2002-06-20	2002-06-20	Astrazeneca Ab	Therapeutic agents
US7351858B2 (en)	2002-06-20	2008-04-01	Astrazeneca Ab	Ortho-substituted benzoic acid derivatives for the treatment of insulin resistance
GB0314129D0 (en)	2003-06-18	2003-07-23	Astrazeneca Ab	Therapeutic agents
GB0314078D0 (en)	2003-06-18	2003-07-23	Astrazeneca Ab	Therapeutic agents
GB0314136D0 (en)	2003-06-18	2003-07-23	Astrazeneca Ab	Therapeutic agents
GB0314130D0 (en)	2003-06-18	2003-07-23	Astrazeneca Ab	Therapeutic agents
GB0314131D0 (en)	2003-06-18	2003-07-23	Astrazeneca Ab	Therapeutic agents
GB0314075D0 (en)	2003-06-18	2003-07-23	Astrazeneca Ab	Therapeutic agents
GB0314260D0 (en)	2003-06-19	2003-07-23	Astrazeneca Ab	Therapeutic agents

2003
- 2003-06-17 EP EP03732713A patent/EP1517883B8/en not_active Expired - Lifetime
- 2003-06-17 ES ES03732713T patent/ES2299702T3/es not_active Expired - Lifetime
- 2003-06-17 DK DK03732713T patent/DK1517883T3/da active
- 2003-06-17 DE DE60319084T patent/DE60319084T2/de not_active Expired - Lifetime
- 2003-06-17 PT PT03732713T patent/PT1517883E/pt unknown
- 2003-06-17 KR KR10-2004-7020670A patent/KR20050014013A/ko not_active Withdrawn
- 2003-06-17 CA CA002489834A patent/CA2489834C/en not_active Expired - Fee Related
- 2003-06-17 AU AU2003240099A patent/AU2003240099B2/en not_active Ceased
- 2003-06-17 MX MXPA04012686A patent/MXPA04012686A/es not_active Application Discontinuation
- 2003-06-17 PL PL03375074A patent/PL375074A1/pl not_active Application Discontinuation
- 2003-06-17 TW TW092116378A patent/TWI282784B/zh not_active IP Right Cessation
- 2003-06-17 US US10/518,007 patent/US7355069B2/en not_active Expired - Fee Related
- 2003-06-17 CN CNB038194740A patent/CN1319938C/zh not_active Expired - Fee Related
- 2003-06-17 RU RU2004137094/04A patent/RU2004137094A/ru not_active Application Discontinuation
- 2003-06-17 WO PCT/GB2003/002584 patent/WO2004000790A1/en not_active Ceased
- 2003-06-17 JP JP2004515007A patent/JP3782818B2/ja not_active Expired - Lifetime
- 2003-06-17 BR BR0311932-7A patent/BR0311932A/pt not_active IP Right Cessation
- 2003-06-17 AT AT03732713T patent/ATE386013T1/de not_active IP Right Cessation
- 2003-06-20 AR ARP030102197A patent/AR039713A1/es not_active Application Discontinuation
2004
- 2004-12-07 NO NO20045353A patent/NO20045353L/no not_active Application Discontinuation
- 2004-12-09 IL IL16567104A patent/IL165671A0/xx unknown
2005
- 2005-01-05 IS IS7627A patent/IS7627A/is unknown
2006
- 2006-01-27 JP JP2006019068A patent/JP2006182782A/ja active Pending

Also Published As

Publication number	Publication date
RU2004137094A (ru)	2005-08-10
DE60319084D1 (de)	2008-03-27
DE60319084T2 (de)	2009-01-29
JP2006182782A (ja)	2006-07-13
CA2489834C (en)	2006-10-03
HK1073838A1 (en)	2005-10-21
IS7627A (is)	2005-01-05
JP2005529970A (ja)	2005-10-06
DK1517883T3 (da)	2008-05-26
TWI282784B (en)	2007-06-21
US20050256198A1 (en)	2005-11-17
JP3782818B2 (ja)	2006-06-07
CA2489834A1 (en)	2003-12-31
BR0311932A (pt)	2005-03-22
MXPA04012686A (es)	2005-03-23
EP1517883B1 (en)	2008-02-13
AU2003240099B2 (en)	2007-02-01
AR039713A1 (es)	2005-03-09
WO2004000790A1 (en)	2003-12-31
CN1675171A (zh)	2005-09-28
AU2003240099A1 (en)	2004-01-06
ES2299702T3 (es)	2008-06-01
KR20050014013A (ko)	2005-02-05
CN1319938C (zh)	2007-06-06
PT1517883E (pt)	2008-04-21
TW200409747A (en)	2004-06-16
PL375074A1 (pl)	2005-11-14
NO20045353L (no)	2005-01-20
EP1517883A1 (en)	2005-03-30
US7355069B2 (en)	2008-04-08
EP1517883B8 (en)	2008-05-21
ATE386013T1 (de)	2008-03-15

Publication	Publication Date	Title
SI1660431T1 (sl)	2009-08-31	Derivati fenoksiocetne kisline
IL147822A0 (en)	2002-08-14	Benzoic acid derivatives for the treatment of diabetes mellitus
IL175550A0 (en)	2006-09-05	Heterocyclic boronic acid compounds
PT1488790E (pt)	2014-10-10	Preparação sólida contendo uma forma de cristal único a de um derivado de ácido tiazolcarboxílico
NO20015909L (no)	2002-01-15	Anvendelse av (-) (3-trihalometylfenoksy) (4-halofenyl) eddiksyrederivater for behandling av insulinresistens, type 2 diabetes, hyperlipidemi og hyperurisemi
AU2003211131A1 (en)	2003-09-04	Metformin salts of lipophilic acids
IL172980A0 (en)	2006-06-11	Novel insulin derivatives
AU2003265382A8 (en)	2004-03-11	Antibacterial benzoic acid derivatives
AU2003234929A1 (en)	2003-12-02	Therapeutic agent for diabetes
SI2107069T1 (sl)	2013-04-30	Novi inzulinski derivati
PL372616A1 (pl)	2005-07-25	Pochodne kwasu fenylo(alkilo)karboksylowego i pochodne dijonowe fenyloalkiloheterocykliczne oraz ich zastosowanie jako leków o aktywności obniżającejglukozy surowiczej i/lub lipidów surowiczych
PL377164A1 (pl)	2006-01-23	Pochodne anilinopirazolu przydatne do leczenia cukrzycy
AU2003257162A1 (en)	2004-03-19	Catheter for cardiac injection
AU3937102A (en)	2002-06-11	Use of(-) (3-halomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type diabetes, hyperlipidemia and hyperuricemia
AU2003289910A1 (en)	2004-06-30	Isophtalic acid derivatives
IL164413A0 (en)	2005-12-18	(2-((-Alkoxy)-phenyl)-cyclopent-1-enyl)aromatic carbo and heterocyclic acid and derivatives
IL165670A0 (en)	2006-01-15	Ortho-substituted benzoic acid derivatives for thetreatment of insulin resistance
PL375074A1 (pl)	2005-11-14	orto-Podstawione pochodne kwasu benzoesowego do leczenia insulinooporności
SI1517883T1 (sl)	2008-06-30	Orto-substituirani derivati benzojske kisline za zdravljenje insulinske rezistence
SI1517679T1 (sl)	2008-06-30	Orto-substituirani derivati benzojske kisline za zdravljenje insulinske rezistence
EP1549617A4 (en)	2009-09-16	SALT OF AMLODIPIN WITH AN ORGANIC ACID
GB0315878D0 (en)	2003-08-13	Aryl carboxylic acid derivatives and their therapeutic use
AU2002335304A1 (en)	2004-05-04	The use of berberine as insulin sensitizer
PL1620085T3 (pl)	2009-01-30	Zastosowanie pochodnych kwasu fenoksyoctowego do leczenia pęcherza nadreaktywnego
ZA200605302B (en)	2007-04-25	Use of pentadienoic acid derivatives for the treatment of hyperuricemia