IL166151A0 - Method and apparatus for fibred high-resolution fluorescence imaging in particular confocal imaging - Google Patents

Method and apparatus for fibred high-resolution fluorescence imaging in particular confocal imaging

Info

Publication number
IL166151A0
IL166151A0 IL16615105A IL16615105A IL166151A0 IL 166151 A0 IL166151 A0 IL 166151A0 IL 16615105 A IL16615105 A IL 16615105A IL 16615105 A IL16615105 A IL 16615105A IL 166151 A0 IL166151 A0 IL 166151A0
Authority
IL
Israel
Prior art keywords
imaging
fiber output
fibred
tissue
fiber
Prior art date
Application number
IL16615105A
Other languages
English (en)
Original Assignee
Mauna Kea Technologies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR0302972A external-priority patent/FR2852394B1/fr
Application filed by Mauna Kea Technologies filed Critical Mauna Kea Technologies
Publication of IL166151A0 publication Critical patent/IL166151A0/xx

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B23/00—Telescopes, e.g. binoculars; Periscopes; Instruments for viewing the inside of hollow bodies; Viewfinders; Optical aiming or sighting devices
    • G02B23/24—Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes
    • G02B23/26—Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes using light guides
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N1/00—Scanning, transmission or reproduction of documents or the like, e.g. facsimile transmission; Details thereof
    • H04N1/024—Details of scanning heads ; Means for illuminating the original
    • H04N1/028—Details of scanning heads ; Means for illuminating the original for picture information pick-up
    • H04N1/0281—Details of scanning heads ; Means for illuminating the original for picture information pick-up with means for collecting light from a line or an area of the original and for guiding it to only one or a relatively low number of picture element detectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A61B5/0068—Confocal scanning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0073—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by tomography, i.e. reconstruction of 3D images from 2D projections
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0028—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders specially adapted for specific applications, e.g. for endoscopes, ophthalmoscopes, attachments to conventional microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0032—Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0036—Scanning details, e.g. scanning stages
    • G02B21/0048—Scanning details, e.g. scanning stages scanning mirrors, e.g. rotating or galvanomirrors, MEMS mirrors
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0072—Optical details of the image generation details concerning resolution or correction, including general design of CSOM objectives
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/008—Details of detection or image processing, including general computer control
    • G02B21/0084—Details of detection or image processing, including general computer control time-scale detection, e.g. strobed, ultra-fast, heterodyne detection
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B23/00—Telescopes, e.g. binoculars; Periscopes; Instruments for viewing the inside of hollow bodies; Viewfinders; Optical aiming or sighting devices
    • G02B23/24—Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B26/00—Optical devices or arrangements for the control of light using movable or deformable optical elements
    • G02B26/08—Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the direction of light
    • G02B26/10—Scanning systems
    • G02B26/101—Scanning systems with both horizontal and vertical deflecting means, e.g. raster or XY scanners
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Radiology & Medical Imaging (AREA)
  • Astronomy & Astrophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Ophthalmology & Optometry (AREA)
  • Multimedia (AREA)
  • Signal Processing (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • General Engineering & Computer Science (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Microscoopes, Condenser (AREA)
  • Instruments For Viewing The Inside Of Hollow Bodies (AREA)
  • Endoscopes (AREA)
IL16615105A 2002-07-18 2005-01-05 Method and apparatus for fibred high-resolution fluorescence imaging in particular confocal imaging IL166151A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0209099A FR2842407B1 (fr) 2002-07-18 2002-07-18 "procede et appareillage d'imagerie de fluorescence confocale fibree"
FR0302972A FR2852394B1 (fr) 2003-03-11 2003-03-11 Procede et appareillage d'imagerie de fluorescence fibree haute resolution
PCT/FR2003/002196 WO2004008952A1 (fr) 2002-07-18 2003-07-11 Procede et appareillage d'imagerie de fluorescence haute resolution par fibre optique et notamment d’imagerie confocale

Publications (1)

Publication Number Publication Date
IL166151A0 true IL166151A0 (en) 2006-01-15

Family

ID=30772000

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16615105A IL166151A0 (en) 2002-07-18 2005-01-05 Method and apparatus for fibred high-resolution fluorescence imaging in particular confocal imaging

Country Status (13)

Country Link
US (1) US7447539B2 (de)
EP (2) EP1986031A3 (de)
JP (1) JP2005532883A (de)
KR (1) KR20050021492A (de)
CN (1) CN100407985C (de)
AT (1) ATE468069T1 (de)
AU (1) AU2003273437B2 (de)
CA (1) CA2491748C (de)
DE (1) DE60332630D1 (de)
ES (1) ES2347871T3 (de)
FR (1) FR2842407B1 (de)
IL (1) IL166151A0 (de)
WO (1) WO2004008952A1 (de)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005089637A2 (en) 2004-03-11 2005-09-29 The General Hospital Corporation Method and system for tomographic imaging using fluorescent proteins
EP1797818A3 (de) * 2004-03-11 2008-02-13 The General Hospital Corporation Verfahren und System für die tomographische Darstellung mit fluoreszierenden Proteinen
FR2868279B1 (fr) * 2004-04-02 2006-06-09 Mauna Kea Technologies Soc Par Procede et systeme de mesure de vitesse du flux sanguin
FR2871358B1 (fr) * 2004-06-14 2007-02-09 Mauna Kea Technologies Soc Par Procede et systeme d'imagerie microscopique de fluorescence fibree multimarquage
WO2006032151A1 (en) * 2004-09-24 2006-03-30 Art, Advanced Research Technologies Inc. Method for fluorescence tomographic imaging
FR2877103B1 (fr) * 2004-10-22 2012-02-10 Mauna Kea Technologies Systeme et procede d'imagerie microscopique multiphotonique fibre d'un echantillon
US7307774B1 (en) 2005-01-24 2007-12-11 The Board Of Trustees Of The Leland Standford Junior University Micro-optical analysis system and approach therefor
US8346346B1 (en) 2005-01-24 2013-01-01 The Board Of Trustees Of The Leland Stanford Junior University Optical analysis system and approach therefor
US8788021B1 (en) 2005-01-24 2014-07-22 The Board Of Trustees Of The Leland Stanford Junior Univerity Live being optical analysis system and approach
JP2009504333A (ja) * 2005-08-15 2009-02-05 ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム 針生検イメージングシステム
US7414729B2 (en) * 2005-10-13 2008-08-19 President And Fellows Of Harvard College System and method for coherent anti-Stokes Raman scattering endoscopy
FR2899088B1 (fr) * 2006-03-31 2008-06-27 Mauna Kea Technologies Soc Par "microscopie de fluorescence fibree a base de bleu de methylene."
GB2443203B (en) * 2006-06-26 2010-04-07 Osspray Ltd Apparatus for detecting infected tissue
FR2904927B1 (fr) * 2006-08-17 2018-05-18 Mauna Kea Technologies Utilisation d'un systeme d'imagerie par fluorescence confocale fibre in vivo in situ, systeme et procede d'imagerie par fluorescence confocale fibres in vivo in situ
US8099156B1 (en) 2006-09-15 2012-01-17 The Board Of Trustees Of The Leland Stanford Junior University Cochlear optical analysis system and approach therefor
JP4892316B2 (ja) 2006-11-06 2012-03-07 株式会社フジクラ マルチコアファイバ
JP5165443B2 (ja) 2007-06-14 2013-03-21 株式会社フジクラ 石英系マルチコア光ファイバ
US8068899B2 (en) * 2007-07-03 2011-11-29 The Board Of Trustees Of The Leland Stanford Junior University Method and system of using intrinsic-based photosensing with high-speed line scanning for characterization of biological thick tissue including muscle
FR2922308B1 (fr) * 2007-10-11 2012-03-16 Mauna Kea Technologies Dispositif d'imagerie modulaire, module pour ce dispositif et procede mis en oeuvre par ce dispositif
EP2268361B8 (de) 2008-04-09 2019-05-22 Julian Itzcovitz Perkutane sonde
WO2009136613A1 (ja) * 2008-05-08 2009-11-12 株式会社 日立ハイテクノロジーズ 自動分析装置
CA2732962A1 (en) 2008-08-04 2010-02-11 University Of Utah Research Foundation Dye application for confocal imaging of cellular microstructure
US8764315B2 (en) 2009-03-12 2014-07-01 Mauna Kea Technologies Connector for a fiber probe and a fiber probe adapted to said connector
CN102036602B (zh) * 2010-03-02 2012-09-05 清华大学 一种可空间编码的并行激发系统及方法
US9833145B2 (en) 2010-08-11 2017-12-05 Snu R&Db Foundation Method for simultaneously detecting fluorescence and raman signals for multiple fluorescence and raman signal targets, and medical imaging device for simultaneously detecting multiple targets using the method
KR101207695B1 (ko) 2010-08-11 2012-12-03 서울대학교산학협력단 형광 및 라만 신호 표적에 대한 형광 및 라만 신호 동시검출방법 및 이를 이용한 표적 동시검출용 의학영상장치
JP5984681B2 (ja) * 2011-01-31 2016-09-06 オリンパス株式会社 蛍光観察装置
WO2013082156A1 (en) 2011-11-28 2013-06-06 The Board Of Trustees Of The Leland Stanford Junior University System and method useful for sarcomere imaging via objective-based microscopy
WO2013153448A2 (en) 2012-04-13 2013-10-17 Mauna Kea Technologies Miniaturized scanning system
WO2014042130A1 (ja) 2012-09-11 2014-03-20 オリンパス株式会社 散乱光計測装置
JP6086741B2 (ja) * 2013-01-29 2017-03-01 オリンパス株式会社 走査型観察装置とその作動方法
CN103169446B (zh) * 2013-04-15 2016-08-10 叶衍铭 适用于内窥镜的早期癌症可疑病灶检查装置
CN105873495B (zh) * 2014-04-17 2018-09-14 奥林巴斯株式会社 光源装置
US10016136B2 (en) 2014-06-20 2018-07-10 Optomak, Inc. Image relaying cannula with detachable self-aligning connector
WO2016061582A1 (en) * 2014-10-17 2016-04-21 C Urchin Technologies Llc Lensless endoscope and other imaging devices
US11154186B2 (en) * 2015-07-31 2021-10-26 University Of Utah Research Foundation Devices, systems, and methods for imaging and treating a selected tissue
CN105534470B (zh) * 2015-12-22 2018-01-30 精微视达医疗科技（武汉）有限公司 一种共焦显微内窥镜系统及其调节方法
EP3413839B1 (de) 2016-02-09 2025-12-31 AMO Groningen B.V. Gleitsichtintraokularlinse und verfahren zur verwendung und herstellung
JP7245051B2 (ja) 2016-03-08 2023-03-23 エンスペクトラ・ヘルス・インコーポレイテッド 皮膚の疾患の非侵襲的な検出
US12133634B2 (en) 2016-04-06 2024-11-05 The University Court Of The University Of Edinburgh Endoscopic imaging apparatus and method
JP6642705B2 (ja) * 2016-05-19 2020-02-12 株式会社ニコン 顕微鏡
GB201611819D0 (en) 2016-07-07 2016-08-17 Univ Court Of The Univ Of Edinburgh The Imaging method and apparatus
WO2018144648A1 (en) 2017-02-01 2018-08-09 University Of Utah Research Foundation Devices and methods for mapping cardiac tissue
EP3614915A4 (de) 2017-04-28 2021-01-20 Enspectra Health, Inc. Systeme und verfahren zur bildgebung und messung von sarkomeren
GB201707239D0 (en) 2017-05-05 2017-06-21 Univ Edinburgh Optical system and method
CN111095074B (zh) * 2017-07-24 2023-06-09 密歇根大学董事会 3轴侧视共聚焦荧光显微内镜
CN108490597A (zh) * 2018-06-05 2018-09-04 张红明 一种基于光纤耦合器的共聚焦显微系统
CN108937824A (zh) * 2018-08-02 2018-12-07 深圳大学 一种内窥成像装置和荧光寿命分布图像的获取方法
CN113473900B (zh) 2018-11-13 2024-09-24 恩斯派克特拉健康公司 用于生成深度剖面的方法和系统
KR102135593B1 (ko) 2018-11-29 2020-07-20 재단법인대구경북과학기술원 다중모드 현미경
US12111209B2 (en) 2018-11-29 2024-10-08 Leica Microsystems Nc, Inc. Compact diffraction limited near infrared (NIR) spectrometers and related detectors
WO2020148450A1 (en) * 2019-01-18 2020-07-23 Institut Hospitalo-Universitaire De Strasbourg System and method for medical navigation
CN109807471B (zh) * 2019-02-01 2024-03-26 佛山科学技术学院 一种激光打标装置及方法
CA3160940A1 (en) 2019-12-17 2021-06-24 Nathan J. KNIGHTON Cardiac tissue characterization using catheterized light scattering spectroscopy
CN111736332B (zh) * 2020-07-02 2025-02-21 中国科学技术大学 一种光纤扫描成像装置及方法
JP7865983B2 (ja) 2021-03-12 2026-05-26 ストライカー・ユーロピアン・オペレーションズ・リミテッド 腫瘍組織を検出および除去するための神経外科的方法およびシステム

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1265087A (de) * 1968-08-27 1972-03-01
US20020045811A1 (en) * 1985-03-22 2002-04-18 Carter Kittrell Laser ablation process and apparatus
NL8702071A (nl) * 1987-09-03 1989-04-03 Philips Nv Inrichting voor het puntsgewijs aftasten van een voorwerp.
US5532873A (en) * 1993-09-08 1996-07-02 Dixon; Arthur E. Scanning beam laser microscope with wide range of magnification
DE69530072T2 (de) * 1994-12-08 2004-03-04 Molecular Dynamics, Sunnyvale System zur fluoreszenzabbildung unter verwendung eines objektivs mit makroabtastung
US5813987A (en) * 1995-08-01 1998-09-29 Medispectra, Inc. Spectral volume microprobe for analysis of materials
JPH0961132A (ja) * 1995-08-28 1997-03-07 Olympus Optical Co Ltd ３次元形状計測装置
DE19612536A1 (de) * 1996-03-29 1997-10-02 Freitag Lutz Dr Anordnung und Verfahren zur Diagnose von malignem Gewebe durch Fluoreszenzbetrachtung
US6388788B1 (en) * 1998-03-16 2002-05-14 Praelux, Inc. Method and apparatus for screening chemical compounds
US6370422B1 (en) * 1998-03-19 2002-04-09 Board Of Regents, The University Of Texas System Fiber-optic confocal imaging apparatus and methods of use
FR2783330B1 (fr) * 1998-09-15 2002-06-14 Assist Publ Hopitaux De Paris Dispositif d'observation de l'interieur d'un corps produisant une qualite d'observation perfectionnee
US6179611B1 (en) * 1999-01-22 2001-01-30 The Regents Of The University Of California Dental optical coherence domain reflectometry explorer
AU2001240121B2 (en) * 2000-03-10 2005-06-23 Textron Systems Corporation Optical probes and methods for spectral analysis
US6748259B1 (en) * 2000-06-15 2004-06-08 Spectros Corporation Optical imaging of induced signals in vivo under ambient light conditions
US7209287B2 (en) * 2000-09-18 2007-04-24 Vincent Lauer Confocal optical scanning device
DE60141090D1 (de) * 2000-10-30 2010-03-04 Gen Hospital Corp Optische systeme zur gewebeanalyse

Also Published As

Publication number Publication date
KR20050021492A (ko) 2005-03-07
EP1523270B1 (de) 2010-05-19
EP1523270A1 (de) 2005-04-20
AU2003273437B2 (en) 2008-02-28
JP2005532883A (ja) 2005-11-04
CA2491748C (fr) 2012-10-23
CA2491748A1 (fr) 2004-01-29
FR2842407B1 (fr) 2005-05-06
CN1681432A (zh) 2005-10-12
WO2004008952A1 (fr) 2004-01-29
ATE468069T1 (de) 2010-06-15
WO2004008952A9 (fr) 2012-06-28
ES2347871T3 (es) 2010-11-24
CN100407985C (zh) 2008-08-06
EP1986031A3 (de) 2009-05-20
US20050242298A1 (en) 2005-11-03
FR2842407A1 (fr) 2004-01-23
EP1986031A2 (de) 2008-10-29
US7447539B2 (en) 2008-11-04
DE60332630D1 (de) 2010-07-01
AU2003273437A1 (en) 2004-02-09

Similar Documents

Publication Publication Date Title
EP1986031A3 (de) Verfahren und Ausrüstung für hochauflösende faseroptische Fluoreszenzbildgebung
JP7249647B2 (ja) 光学システムと方法
AU2005256758B2 (en) Multimarking fiber fluorescence microscopic imagery system and method
EP2653091B1 (de) Abtastendoskop
US20110031414A1 (en) Device for microscopy having selective illumination of a plane
ATE204086T1 (de) Vorrichtung und verfahren zum optischen messen eines probenpunktes einer probe mit hoher ortsauflösung
EP2693201A1 (de) Vorrichtung für photometrische analyse, verfahren für photometrische analyse und computerprogramm für photometrische analyse mit erkennung einzelner lichtemittierender partikel
JP2008517291A5 (de)
KR20180105118A (ko) 다중모드 형광 이미징 유동 세포 계측 시스템
WO2007084915A2 (en) Scanning fiber-optic nonlinear optical imaging and spectroscopy endoscope
EP1775569A3 (de) Cantilever-Array, Verfahren zur Herstellung des Arrays sowie Rastersondenmikroskop, Gleitvorrichtung eines Führungs- und Rotationsmechanismus, Sensor, Homodyn-Laser-Interferometer und Laser-Dopplerinterferometer mit Funktion zur Lichtanregung der Probe unter Verwendung des Arrays und Cantilevers
JP5210823B2 (ja) 光走査型内視鏡、光走査型内視鏡プロセッサ、および光走査型内視鏡装置
CA3124962A1 (en) Optical waveguides and couplers for delivering light to an array of photonic elements
WO2006045936A3 (fr) Systeme et procede d’imagerie microscopique multiphotonique fibre d’un echantillon
WO2001069302A3 (en) Fiber optic scanner
ATE404977T1 (de) System und verfahren zur erkennung der verschiebung mehrerer mikro- und nanomechanischer elemente wie zum beispiel mikro-kragträgern
KR20150035035A (ko) 다초점 레이저 스캐닝 현미경 시스템
JP2005328990A (ja) 生体情報測定装置および内視鏡装置
EP1672355A3 (de) Verbessertes Verfahren zum Abtasten und Lichtsammeln für einen Detektor für seltene Zellen
CN1773257A (zh) 水体污染激光诱导荧光遥测方法
US8269964B2 (en) Photon measurement method and apparatus
EP1855139B1 (de) Verfahren und Vorrichtung zum Erfassen von Signalen konfokaler Bilder und Vorrichtung zum Erfassen des Standes der Probenahme
CN111938579A (zh) 一种基于光纤延时的提升光声图像质量的多脉冲光声显微成像方法及其装置
EP2160974B1 (de) Abbildungssystem
JP2012208442A (ja) 走査型顕微鏡および走査型顕微鏡システム

Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
KB Patent renewed
KB Patent renewed