IL175063A - Use of pif peptides in the manufacture of a medicament for treating intolerance to embryo implantation - Google Patents
Use of pif peptides in the manufacture of a medicament for treating intolerance to embryo implantationInfo
- Publication number
- IL175063A IL175063A IL175063A IL17506306A IL175063A IL 175063 A IL175063 A IL 175063A IL 175063 A IL175063 A IL 175063A IL 17506306 A IL17506306 A IL 17506306A IL 175063 A IL175063 A IL 175063A
- Authority
- IL
- Israel
- Prior art keywords
- pif
- seq
- peptide
- peptides
- embryo
- Prior art date
Links
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- 125000000714 pyrimidinyl group Chemical group 0.000 description 1
- 125000000719 pyrrolidinyl group Chemical group 0.000 description 1
- 125000001422 pyrrolinyl group Chemical group 0.000 description 1
- 125000000168 pyrrolyl group Chemical group 0.000 description 1
- 230000000306 recurrent effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000001850 reproductive effect Effects 0.000 description 1
- 229930002330 retinoic acid Natural products 0.000 description 1
- 238000004007 reversed phase HPLC Methods 0.000 description 1
- 206010039073 rheumatoid arthritis Diseases 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
- 108010071207 serylmethionine Proteins 0.000 description 1
- 229940126586 small molecule drug Drugs 0.000 description 1
- 229940036051 sojourn Drugs 0.000 description 1
- 125000006850 spacer group Chemical group 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 108010004034 stable plasma protein solution Proteins 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 238000006277 sulfonation reaction Methods 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 230000001839 systemic circulation Effects 0.000 description 1
- 125000001113 thiadiazolyl group Chemical group 0.000 description 1
- 125000000335 thiazolyl group Chemical group 0.000 description 1
- 125000001544 thienyl group Chemical group 0.000 description 1
- 150000007970 thio esters Chemical class 0.000 description 1
- 125000005505 thiomorpholino group Chemical group 0.000 description 1
- 125000004568 thiomorpholinyl group Chemical group 0.000 description 1
- 108010061238 threonyl-glycine Proteins 0.000 description 1
- 229940104230 thymidine Drugs 0.000 description 1
- 238000013518 transcription Methods 0.000 description 1
- 230000035897 transcription Effects 0.000 description 1
- 230000014616 translation Effects 0.000 description 1
- 229960001727 tretinoin Drugs 0.000 description 1
- 125000001425 triazolyl group Chemical group 0.000 description 1
- 210000000251 trophoblastic cell Anatomy 0.000 description 1
- 210000003954 umbilical cord Anatomy 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
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- 239000003981 vehicle Substances 0.000 description 1
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- 230000036642 wellbeing Effects 0.000 description 1
- BPICBUSOMSTKRF-UHFFFAOYSA-N xylazine Chemical compound CC1=CC=CC(C)=C1NC1=NCCCS1 BPICBUSOMSTKRF-UHFFFAOYSA-N 0.000 description 1
- 229960001600 xylazine Drugs 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/24—Immunology or allergic disorders
- G01N2800/245—Transplantation related diseases, e.g. graft versus host disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/367—Infertility, e.g. sperm disorder, ovulatory dysfunction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Reproductive Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pathology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Rheumatology (AREA)
- Rehabilitation Therapy (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Genetics & Genomics (AREA)
- Gynecology & Obstetrics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51337003P | 2003-10-22 | 2003-10-22 | |
| US48224403A | 2003-12-22 | 2003-12-22 | |
| PCT/US2004/035382 WO2005040196A2 (fr) | 2003-10-22 | 2004-10-22 | Activites biologiques de peptides pif, site d'action, et anticorps pour detecter pif |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL175063A0 IL175063A0 (en) | 2006-08-20 |
| IL175063A true IL175063A (en) | 2011-10-31 |
Family
ID=34526220
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL175063A IL175063A (en) | 2003-10-22 | 2006-04-20 | Use of pif peptides in the manufacture of a medicament for treating intolerance to embryo implantation |
Country Status (5)
| Country | Link |
|---|---|
| AU (1) | AU2004284097B2 (fr) |
| CA (1) | CA2584690C (fr) |
| IL (1) | IL175063A (fr) |
| NZ (1) | NZ547139A (fr) |
| WO (1) | WO2005040196A2 (fr) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8222211B2 (en) | 2001-07-02 | 2012-07-17 | Bioincept, Llc | Methods of administering PIF agonist peptides and uses thereof |
| US7273708B2 (en) | 2001-07-02 | 2007-09-25 | Bioincept, Llc | Assays for preimplantation factor and preimplantation factor peptides |
| US7723289B2 (en) * | 2003-10-22 | 2010-05-25 | Bioincept, Llc | PIF tetrapeptides |
| US7723290B2 (en) | 2004-10-22 | 2010-05-25 | Bioincept, Llc | Compositions and methods for modulating the immune system |
| US9737585B2 (en) | 2011-03-02 | 2017-08-22 | Bioincept, Llc | Compositions and methods for treatment of intracellular damage and bacterial infection |
| WO2017039751A1 (fr) | 2015-08-28 | 2017-03-09 | Bioincept, Llc | Peptides mutants et procédés de traitement de sujets les employant |
| EP2970496B1 (fr) | 2013-03-12 | 2018-07-18 | Institute of Arthritis Research LLC | Polypeptide actif d'un point de vue immunologique |
| EP3060924B1 (fr) * | 2013-10-22 | 2022-06-01 | Bioincept LLC | Cellules transfectées par un pif et procédés d'utilisation |
| US20170336406A1 (en) * | 2014-09-16 | 2017-11-23 | Bioincept, Llc | Pif binding as a marker for immune dysregulation |
| JP6806685B2 (ja) * | 2014-09-16 | 2021-01-06 | バイオインセプト、エルエルシー | 急性放射線症候群を治療するための組成物及び方法 |
| EP3341006A4 (fr) | 2015-08-28 | 2019-03-13 | BioIncept LLC | Compositions et méthodes pour le traitement d'une lésion neurologique |
| US20240293501A1 (en) * | 2020-06-18 | 2024-09-05 | Michael J. Paidas | Reagents, Pharmaceutical Formulations, and Methods for Treating and Preventing Viral Infection |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7273708B2 (en) | 2001-07-02 | 2007-09-25 | Bioincept, Llc | Assays for preimplantation factor and preimplantation factor peptides |
| WO2004053086A2 (fr) * | 2002-12-06 | 2004-06-24 | Epimmune, Inc. | Antigenes de plasmodium falciparum et procedes d'utilisation |
-
2004
- 2004-10-22 WO PCT/US2004/035382 patent/WO2005040196A2/fr not_active Ceased
- 2004-10-22 NZ NZ547139A patent/NZ547139A/en not_active IP Right Cessation
- 2004-10-22 CA CA2584690A patent/CA2584690C/fr not_active Expired - Fee Related
- 2004-10-22 AU AU2004284097A patent/AU2004284097B2/en not_active Ceased
-
2006
- 2006-04-20 IL IL175063A patent/IL175063A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| AU2004284097B2 (en) | 2011-05-12 |
| AU2004284097A1 (en) | 2005-05-06 |
| IL175063A0 (en) | 2006-08-20 |
| CA2584690C (fr) | 2015-10-06 |
| WO2005040196A3 (fr) | 2006-08-17 |
| NZ547139A (en) | 2009-12-24 |
| CA2584690A1 (fr) | 2005-05-06 |
| WO2005040196A2 (fr) | 2005-05-06 |
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| Date | Code | Title | Description |
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| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed |