IL199941A - Stable Thyacomycin preparations - Google Patents

Stable Thyacomycin preparations

Info

Publication number: IL199941A
Authority: IL; Israel
Prior art keywords: tiacumicins; compositions; stable; stable tiacumicins
Prior art date: 2007-01-19

Application number

IL199941A

Other languages

English (en)

Hebrew (he)

Other versions

IL199941A0 (en

Original Assignee

Merck Sharp & Dohme

Optimer Pharmaceuticals Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-01-19

Filing date

2009-07-19

Publication date

2016-02-29

2009-07-19 Application filed by Merck Sharp & Dohme, Optimer Pharmaceuticals Llc filed Critical Merck Sharp & Dohme

2010-04-15 Publication of IL199941A0 publication Critical patent/IL199941A0/en

2016-02-29 Publication of IL199941A publication Critical patent/IL199941A/en

Links

229930187202 Tiacumicin Natural products 0.000 title 1
239000000203 mixture Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Virology (AREA)
Genetics & Genomics (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

IL199941A 2007-01-19 2009-07-19 Stable Thyacomycin preparations IL199941A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US88113707P	2007-01-19	2007-01-19
PCT/US2008/000591 WO2008091518A1 (en)	2007-01-19	2008-01-17	Compositions of stable tiacumicins

Publications (2)

Publication Number	Publication Date
IL199941A0 IL199941A0 (en)	2010-04-15
IL199941A true IL199941A (en)	2016-02-29

Family

ID=39641896

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL199941A IL199941A (en)	2007-01-19	2009-07-19	Stable Thyacomycin preparations

Country Status (22)

Country	Link
US (2)	US20080176927A1 (pt)
EP (1)	EP2121716B1 (pt)
JP (2)	JP5635266B2 (pt)
KR (1)	KR101491729B1 (pt)
CN (2)	CN105169396A (pt)
BR (1)	BRPI0806713A8 (pt)
CA (1)	CA2676003C (pt)
CY (1)	CY1117237T1 (pt)
DK (1)	DK2121716T3 (pt)
ES (1)	ES2560669T3 (pt)
HR (1)	HRP20151438T1 (pt)
HU (1)	HUE028671T2 (pt)
IL (1)	IL199941A (pt)
MX (1)	MX2009007784A (pt)
NZ (1)	NZ578493A (pt)
PL (1)	PL2121716T3 (pt)
PT (1)	PT2121716E (pt)
RU (1)	RU2484829C2 (pt)
SI (1)	SI2121716T1 (pt)
TW (1)	TWI474820B (pt)
WO (1)	WO2008091518A1 (pt)
ZA (1)	ZA200905134B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8586551B2 (en)	2005-01-31	2013-11-19	Optimer Pharmaceuticals, Inc.	18-membered macrocycles and analogs thereof
US7378508B2 (en)	2007-01-22	2008-05-27	Optimer Pharmaceuticals, Inc.	Polymorphic crystalline forms of tiacumicin B
TWI523654B (zh)	2007-11-27	2016-03-01	默沙東藥廠	抗生素巨環化合物以及其製造及使用之方法
BR112012029259A8 (pt) *	2010-05-18	2021-03-23	Optimer Pharmaceuticals Inc	tratamento de infecção por clostridium difficile em pacientes sob terapia de antibióticos
WO2011146624A2 (en) *	2010-05-18	2011-11-24	Optimer Pharmaceuticals, Inc.	Methods of treating recurring bacterial infection
CN105287473A (zh) *	2010-06-02	2016-02-03	扩散药品有限公司	包含双极性反式类胡萝卜素的组合物及其应用
MX2013009033A (es) *	2011-02-04	2013-09-06	Optimer Pharmaceuticals Inc	Tratamiento de infecciones bacterianas.
ITMI20120560A1 (it)	2012-04-05	2013-10-06	Olon Spa	Procedimento per la purificazione della tiacumicina b
JO3464B1 (ar)	2013-01-15	2020-07-05	Astellas Pharma Europe Ltd	التركيبات الخاصة بمركبات التياكوميسين
US20150141356A1 (en) *	2013-11-15	2015-05-21	Optimer Pharmaceuticals, Inc.	Treatment of Clostridium Difficile Infection in High Risk Patients
WO2015127955A1 (en)	2014-02-25	2015-09-03	Olon S.P.A.	A new polymorph of tiacumicin b and process for preparation thereof
WO2015169451A1 (en) *	2014-05-09	2015-11-12	Astellas Pharma Europe Ltd	Treatment regimen tiacumicin compound
CN110037992B (zh) *	2019-05-28	2021-05-28	杭州华东医药集团新药研究院有限公司	一种稳定的非达霉素组合物
CN112353774B (zh) *	2020-11-17	2022-08-23	浙江汇能生物股份有限公司	一种那西肽风味咀嚼片及其制备方法及其在犬魏氏梭菌病上的用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH05192094A (ja) *	1991-09-03	1993-08-03	Takeda Chem Ind Ltd	造粒組成物
US5583115A (en) *	1995-05-09	1996-12-10	Abbott Laboratories	Dialkyltiacumicin compounds
WO2002032427A1 (en) *	2000-10-20	2002-04-25	Galephar M/F	Stable oral formulation containing benzimidazole derivative
US20030099699A1 (en) *	2001-11-13	2003-05-29	Hanshew Dwight D.	Storage stable thyroxine active drug formulations and methods for their production
WO2006085838A1 (en) *	2005-01-31	2006-08-17	Optimer Pharmaceuticals, Inc.	18-membered macrocycles and analogs thereof
US7507564B2 (en) *	2002-07-29	2009-03-24	Optimer Pharmaceuticals, Inc.	Tiacumicin production
US9211259B2 (en) *	2002-11-29	2015-12-15	Foamix Pharmaceuticals Ltd.	Antibiotic kit and composition and uses thereof
US20040224020A1 (en) *	2002-12-18	2004-11-11	Schoenhard Grant L.	Oral dosage forms with therapeutically active agents in controlled release cores and immediate release gelatin capsule coats
US7906489B2 (en) *	2004-05-14	2011-03-15	Optimer Pharmaceuticals, Inc.	18-membered macrocycles and analogs thereof

2008
- 2008-01-14 US US12/008,751 patent/US20080176927A1/en not_active Abandoned
- 2008-01-17 JP JP2009546419A patent/JP5635266B2/ja active Active
- 2008-01-17 CN CN201510502516.0A patent/CN105169396A/zh active Pending
- 2008-01-17 HU HUE08724557A patent/HUE028671T2/en unknown
- 2008-01-17 PT PT87245577T patent/PT2121716E/pt unknown
- 2008-01-17 SI SI200831576T patent/SI2121716T1/sl unknown
- 2008-01-17 DK DK08724557.7T patent/DK2121716T3/en active
- 2008-01-17 EP EP08724557.7A patent/EP2121716B1/en active Active
- 2008-01-17 NZ NZ578493A patent/NZ578493A/en unknown
- 2008-01-17 ES ES08724557.7T patent/ES2560669T3/es active Active
- 2008-01-17 CN CN2008800078761A patent/CN102015747A/zh active Pending
- 2008-01-17 RU RU2009128612/15A patent/RU2484829C2/ru active
- 2008-01-17 CA CA2676003A patent/CA2676003C/en active Active
- 2008-01-17 PL PL08724557T patent/PL2121716T3/pl unknown
- 2008-01-17 KR KR1020097017319A patent/KR101491729B1/ko not_active Expired - Fee Related
- 2008-01-17 BR BRPI0806713A patent/BRPI0806713A8/pt not_active Application Discontinuation
- 2008-01-17 WO PCT/US2008/000591 patent/WO2008091518A1/en not_active Ceased
- 2008-01-17 HR HRP20151438TT patent/HRP20151438T1/hr unknown
- 2008-01-17 MX MX2009007784A patent/MX2009007784A/es active IP Right Grant
- 2008-03-10 TW TW097108321A patent/TWI474820B/zh active
2009
- 2009-07-19 IL IL199941A patent/IL199941A/en active IP Right Grant
- 2009-07-22 ZA ZA2009/05134A patent/ZA200905134B/en unknown
2012
- 2012-03-09 US US13/416,768 patent/US20130065844A1/en not_active Abandoned
2014
- 2014-06-24 JP JP2014129106A patent/JP5995331B2/ja active Active
2016
- 2016-03-01 CY CY20161100177T patent/CY1117237T1/el unknown

Also Published As

Publication number	Publication date
NZ578493A (en)	2012-02-24
JP2014205701A (ja)	2014-10-30
US20130065844A1 (en)	2013-03-14
ES2560669T3 (es)	2016-02-22
AU2008209623A2 (en)	2010-01-28
DK2121716T3 (en)	2016-03-14
CN102015747A (zh)	2011-04-13
CA2676003A1 (en)	2008-07-31
PL2121716T3 (pl)	2016-04-29
PT2121716E (pt)	2016-03-03
CA2676003C (en)	2012-04-10
TW200938187A (en)	2009-09-16
CN105169396A (zh)	2015-12-23
HRP20151438T1 (hr)	2016-01-29
US20080176927A1 (en)	2008-07-24
JP5635266B2 (ja)	2014-12-03
JP2010516677A (ja)	2010-05-20
BRPI0806713A2 (pt)	2011-09-13
SI2121716T1 (sl)	2016-03-31
KR101491729B1 (ko)	2015-02-09
KR20090107061A (ko)	2009-10-12
RU2484829C2 (ru)	2013-06-20
EP2121716A1 (en)	2009-11-25
EP2121716A4 (en)	2013-06-12
RU2009128612A (ru)	2011-02-27
AU2008209623A1 (en)	2008-07-31
EP2121716B1 (en)	2015-12-09
ZA200905134B (en)	2013-08-28
TWI474820B (zh)	2015-03-01
IL199941A0 (en)	2010-04-15
MX2009007784A (es)	2010-02-11
CY1117237T1 (el)	2017-04-05
WO2008091518A1 (en)	2008-07-31
JP5995331B2 (ja)	2016-09-21
BRPI0806713A8 (pt)	2017-04-18
HUE028671T2 (en)	2016-12-28

Legal Events

Date	Code	Title
2016-06-30	FF	Patent granted
2016-06-30	KB	Patent renewed
2017-12-31	KB	Patent renewed

Publication	Publication Date	Title
ZA201103926B (en)	2013-09-25	Stable sulfoximine-insecticide compositions
IL199941A0 (en)	2010-04-15	Compositions of stable tiacumicins
EP2219637A4 (en)	2012-01-11	AVENANTHRAMIDE COMPOSITIONS
IL199656A0 (en)	2010-04-15	Tablet-in-tablet compositions
GB0724342D0 (en)	2008-01-30	Anitbacterial compositions
LT2634231T (lt)	2022-08-25	Sudėtys
GB0810404D0 (en)	2008-07-09	Compositions
GB0711683D0 (en)	2007-07-25	Compositions
GB0722484D0 (en)	2007-12-27	Solid compositions
GB0812041D0 (en)	2008-08-06	Compositions
GB0712024D0 (en)	2007-08-01	Compositions
GB0703679D0 (en)	2007-04-04	Perfume compositions
GB0808537D0 (en)	2008-06-18	Compositions
PL2118255T5 (pl)	2024-07-29	Środek czyszczący
GB0818804D0 (en)	2008-11-19	Compositions
GB0713707D0 (en)	2007-08-22	Stable compositions
ZA201002504B (en)	2011-06-29	Novel taxoid-based compositions
GB0712043D0 (en)	2007-08-01	Compositions
GB0711685D0 (en)	2007-07-25	Compositions
GB0711689D0 (en)	2007-07-25	Compositions
GB0706047D0 (en)	2007-05-09	Anit-viral compositions
GB0700477D0 (en)	2007-02-21	Compositions
GB0723803D0 (en)	2008-01-16	Compositions
GB0708492D0 (en)	2007-06-06	Compositions
GB0703964D0 (en)	2007-04-11	Compositions