IL283998A - NK cells are derived from a mononuclear cell and methods - Google Patents
NK cells are derived from a mononuclear cell and methodsInfo
- Publication number
- IL283998A IL283998A IL283998A IL28399821A IL283998A IL 283998 A IL283998 A IL 283998A IL 283998 A IL283998 A IL 283998A IL 28399821 A IL28399821 A IL 28399821A IL 283998 A IL283998 A IL 283998A
- Authority
- IL
- Israel
- Prior art keywords
- cells
- methods
- cell derived
- mononuclear cell
- mononuclear
- Prior art date
Links
- 210000005087 mononuclear cell Anatomy 0.000 title 1
- 210000000822 natural killer cell Anatomy 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0646—Natural killers cells [NK], NKT cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2315—Interleukin-15 (IL-15)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/515—CD3, T-cell receptor complex
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/599—Cell markers; Cell surface determinants with CD designations not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2019/040867 WO2021006875A1 (en) | 2019-07-08 | 2019-07-08 | Mononuclear cell derived nk cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL283998A true IL283998A (en) | 2021-07-29 |
Family
ID=74114919
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL283998A IL283998A (en) | 2019-07-08 | 2021-06-14 | NK cells are derived from a mononuclear cell and methods |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP3853354A4 (de) |
| JP (2) | JP7213976B2 (de) |
| KR (1) | KR102755940B1 (de) |
| CN (1) | CN113166726A (de) |
| AU (1) | AU2019456283B2 (de) |
| IL (1) | IL283998A (de) |
| SG (1) | SG11202104339WA (de) |
| WO (1) | WO2021006875A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7792426B2 (ja) * | 2021-03-03 | 2025-12-25 | イミュニティバイオ，インコーポレーテッド | 極めて強力なｍ－ｃｅｎｋ細胞及び方法 |
| WO2022216992A1 (en) * | 2021-04-08 | 2022-10-13 | Board Of Regents, The University Of Texas System | Methods for activation and expansion of natural killer cells and combinations with bispecific antibodies |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102428173B (zh) * | 2009-03-26 | 2014-07-30 | 细胞维护北欧制药公司 | Nk细胞的扩增 |
| CA3080368A1 (en) | 2009-12-04 | 2011-06-09 | Stem Cell & Regenerative Medicine International, Inc. | Method of generating natural killer cells and dendritic cells from human embryonic stem cell-derived hemangioblasts |
| US20130059379A1 (en) | 2010-02-24 | 2013-03-07 | Ingo Schmidt-Wolf | Method for the generation of a cik cell and nk cell population |
| US8507222B2 (en) | 2010-09-21 | 2013-08-13 | Altor Bioscience Corporation | Multimeric IL-15 soluble fusion molecules and methods of making and using same |
| WO2012099093A1 (ja) | 2011-01-21 | 2012-07-26 | 株式会社日本バイオセラピー研究所 | Nk細胞強化型血液製剤の製造方法 |
| WO2012128622A1 (en) | 2011-03-18 | 2012-09-27 | Ipd-Therapeutics B.V. | Generation of nk cells and nk-cell progenitors |
| DK2812011T3 (da) | 2012-02-08 | 2020-02-24 | Glycostem Therapeutics B V | Differentiering ex vivo af nk-celler fra cd34+ hæmatopoietiske celler |
| CN102988415B (zh) | 2012-08-15 | 2014-11-19 | 中航（宁夏）生物有限责任公司 | 人异基因有核细胞工业化制备自然杀伤性细胞(nk)及注射液 |
| JP5997296B2 (ja) * | 2013-01-15 | 2016-09-28 | 阿部 博幸 | 免疫細胞含有組成物の製造方法及び癌治療用組成物 |
| WO2015154012A1 (en) * | 2014-04-03 | 2015-10-08 | Memorial Sloan-Kettering Cancer Center | Clonogenic natural killer (nk) cell populations and methods of producing and using such populations |
| CN106232801A (zh) | 2014-04-28 | 2016-12-14 | 维瓦生物细胞股份公司 | 自动化细胞培养和收获装置 |
| KR101683614B1 (ko) * | 2016-02-15 | 2016-12-07 | 신동혁 | Nk세포배양용 배지첨가키트 및 상기 키트를 이용한 nk세포배양방법 |
| US12186342B2 (en) * | 2016-09-23 | 2025-01-07 | The Regents Of The University Of California | Autologous irradiated whole cell tumor vaccines lentivirally engineered to express CD80, IL-15 and IL-15 receptor alpha |
| MY203000A (en) | 2016-10-14 | 2024-06-01 | Xencor Inc | Il15/il15r� heterodimeric fc-fusion proteins |
| AU2018226526B2 (en) * | 2017-02-28 | 2025-03-13 | Affimed Gmbh | Combination of an anti-CD16A antibody with a cytokine |
| KR102867975B1 (ko) | 2017-03-06 | 2025-10-14 | 알토 바이오사이언스 엘엘씨 | Il-12 및 il-18로의 il-15-기반 융합 |
| AU2018265534A1 (en) * | 2017-05-11 | 2019-10-31 | Nantkwest, Inc. | Anti-EGFR/high affinity NK-cells compositions and methods for chordoma treatment |
| EP3634437A4 (de) * | 2017-05-19 | 2020-11-18 | Case Western Reserve University | Zusammensetzungen und verfahren zur ex-vivo-expansion natürlicher killerzellen und deren therapeutische verwendungen |
| CN108070556A (zh) * | 2017-07-26 | 2018-05-25 | 深圳市北科生物科技有限公司 | 用于免疫细胞培养的方法和组合物 |
| JP2020533971A (ja) * | 2017-08-28 | 2020-11-26 | アルター・バイオサイエンス・コーポレーション | Ｉｌ−１５をベースとするｉｌ−７及びｉｌ−２１への融合物 |
| CN109666640B (zh) * | 2019-01-14 | 2020-06-16 | 武汉睿健医药科技有限公司 | 自然杀伤细胞体外纯培养的方法 |
-
2019
- 2019-07-08 AU AU2019456283A patent/AU2019456283B2/en active Active
- 2019-07-08 SG SG11202104339WA patent/SG11202104339WA/en unknown
- 2019-07-08 KR KR1020217018216A patent/KR102755940B1/ko active Active
- 2019-07-08 EP EP19936966.1A patent/EP3853354A4/de active Pending
- 2019-07-08 WO PCT/US2019/040867 patent/WO2021006875A1/en not_active Ceased
- 2019-07-08 JP JP2021527968A patent/JP7213976B2/ja active Active
- 2019-07-08 CN CN201980078702.2A patent/CN113166726A/zh active Pending
-
2021
- 2021-06-14 IL IL283998A patent/IL283998A/en unknown
-
2023
- 2023-01-10 JP JP2023001780A patent/JP2023040184A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP7213976B2 (ja) | 2023-01-27 |
| JP2022513614A (ja) | 2022-02-09 |
| EP3853354A4 (de) | 2022-04-20 |
| WO2021006875A1 (en) | 2021-01-14 |
| EP3853354A1 (de) | 2021-07-28 |
| SG11202104339WA (en) | 2021-05-28 |
| AU2019456283A1 (en) | 2021-05-20 |
| JP2023040184A (ja) | 2023-03-22 |
| KR102755940B1 (ko) | 2025-01-15 |
| CA3120695A1 (en) | 2021-01-14 |
| AU2019456283B2 (en) | 2023-06-08 |
| CN113166726A (zh) | 2021-07-23 |
| KR20210080566A (ko) | 2021-06-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL277703A (en) | T-cell receptors and transgenic cells expressing them | |
| EP3904278A4 (de) | Feststoffelektrolytmaterial und batterie damit | |
| GB2594192B (en) | Fuel cell unit and fuel cell stack | |
| EP3883035A4 (de) | Festelektrolyt und batterie mit verwendung davon | |
| EP3292578A4 (de) | Elektrochemische wasserstoffspeichernde elektroden und zellen | |
| EP3644423A4 (de) | Elektrochemische zelle und elektrochemischer stapel | |
| EP3905276A4 (de) | Feststoffelektrolytmaterial und batterie mit verwendung davon | |
| GB2601481B (en) | Electrochemical cell | |
| SG10201912442SA (en) | Cell System And Method For Storing Cells | |
| IL268909A (en) | Electrochemical cells and batteries | |
| EP3996166A4 (de) | Feststoffelektrolytmaterial und batterie mit verwendung davon | |
| EP3905273A4 (de) | Festelektrolyt und batterie mit verwendung davon | |
| GB2589592B (en) | Improved fuel cell systems and methods | |
| GB2603882B (en) | Cell unit and cell stack | |
| IL283998A (en) | NK cells are derived from a mononuclear cell and methods | |
| EP3985753A4 (de) | Elektrochemische zelle und darin enthaltenes aussenmaterial | |
| EP3588644B8 (de) | Elektrochemische reaktionseinheit und elektrochemischer reaktionszellenstapel | |
| GB201708175D0 (en) | Rechargeable electrochemical cells, methods for their manufacture and operation | |
| SG10201907378QA (en) | Genetically modified nk cells and uses thereof | |
| EP3935684A4 (de) | Elektrochemische durchflusszelle | |
| EP3995452A4 (de) | Feststoffelektrolytmaterial und batterie mit verwendung davon | |
| EP3994762C0 (de) | Zellverbinder für zellen und zellmodule und batteriemodule mit zellen | |
| SG10201909544YA (en) | Genetically Modified T Cells And Uses Thereof | |
| GB2570892B (en) | Electrochemical cell stack | |
| GB2557182B (en) | Electrode and electrochemical cell comprising the same |