IL322948A - Methods and apparatus for preparing RNA covered by fed-batch transcription - Google Patents

Methods and apparatus for preparing RNA covered by fed-batch transcription

Info

Publication number
IL322948A
IL322948A IL322948A IL32294825A IL322948A IL 322948 A IL322948 A IL 322948A IL 322948 A IL322948 A IL 322948A IL 32294825 A IL32294825 A IL 32294825A IL 322948 A IL322948 A IL 322948A
Authority
IL
Israel
Prior art keywords
reaction
nucleotide
rna
cap
competing
Prior art date
Application number
IL322948A
Other languages
English (en)
Hebrew (he)
Inventor
Asbeck Alexander Van
Original Assignee
Ribopro B V
Asbeck Alexander Van
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ribopro B V, Asbeck Alexander Van filed Critical Ribopro B V
Publication of IL322948A publication Critical patent/IL322948A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
IL322948A 2023-02-28 2024-02-27 Methods and apparatus for preparing RNA covered by fed-batch transcription IL322948A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB2302887.1A GB202302887D0 (en) 2023-02-28 2023-02-28 Rna
PCT/EP2024/054929 WO2024180048A2 (fr) 2023-02-28 2024-02-27 Arn

Publications (1)

Publication Number Publication Date
IL322948A true IL322948A (en) 2025-10-01

Family

ID=85794061

Family Applications (1)

Application Number Title Priority Date Filing Date
IL322948A IL322948A (en) 2023-02-28 2024-02-27 Methods and apparatus for preparing RNA covered by fed-batch transcription

Country Status (9)

Country Link
EP (1) EP4673553A2 (fr)
JP (1) JP2026506804A (fr)
KR (1) KR20250161571A (fr)
CN (1) CN121263530A (fr)
AU (1) AU2024229166A1 (fr)
GB (1) GB202302887D0 (fr)
IL (1) IL322948A (fr)
MX (1) MX2025010001A (fr)
WO (1) WO2024180048A2 (fr)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7074596B2 (en) 2002-03-25 2006-07-11 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Synthesis and use of anti-reverse mRNA cap analogues
US20050287539A1 (en) * 2004-06-29 2005-12-29 Emmanuel Labourier Methods and compositions for preparing capped RNA
CN113874502A (zh) 2019-03-11 2021-12-31 摩登纳特斯有限公司 补料分批体外转录方法
CA3173131A1 (fr) * 2020-04-16 2021-10-21 Michael Humbert Fabrication et purification in vitro d'arnm therapeutique

Also Published As

Publication number Publication date
WO2024180048A3 (fr) 2025-02-27
GB202302887D0 (en) 2023-04-12
EP4673553A2 (fr) 2026-01-07
WO2024180048A2 (fr) 2024-09-06
KR20250161571A (ko) 2025-11-17
JP2026506804A (ja) 2026-02-26
AU2024229166A1 (en) 2025-10-09
CN121263530A (zh) 2026-01-02
MX2025010001A (es) 2025-11-03

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