IL34670A - Pharmaceutical preparations containing 2-) 2,6-dichlorophenyl-amino (-1,3-diazacicopentane-) 2) and / or its acidic salt salts - Google Patents

Pharmaceutical preparations containing 2-) 2,6-dichlorophenyl-amino (-1,3-diazacicopentane-) 2) and / or its acidic salt salts

Info

Publication number: IL34670A
Authority: IL; Israel
Prior art keywords: dichlorophenyl; compositions; amino; diazacyclopentene; acid addition
Prior art date: 1969-06-06

Application number

IL34670A

Other languages

English (en)

Hebrew (he)

Other versions

IL34670A0 (en

Original Assignee

Boehringer Sohn Ingelheim

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1969-06-06

Filing date

1970-06-05

Publication date

1972-10-29

1970-06-05 Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim

1970-08-19 Publication of IL34670A0 publication Critical patent/IL34670A0/xx

1972-10-29 Publication of IL34670A publication Critical patent/IL34670A/en

Links

239000002253 acid Substances 0.000 title claims description 8
150000003839 salts Chemical class 0.000 title claims description 8
239000008194 pharmaceutical composition Substances 0.000 title claims description 7
239000000203 mixture Substances 0.000 claims description 16
206010027599 migraine Diseases 0.000 claims description 15
208000019695 Migraine disease Diseases 0.000 claims description 14
239000004480 active ingredient Substances 0.000 claims description 14
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 4
239000003814 drug Substances 0.000 claims description 4
-1 2 , 6-dichlorophenyl-amino Chemical group 0.000 claims description 3
229910002651 NO3 Inorganic materials 0.000 claims description 3
NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 claims description 3
239000002775 capsule Substances 0.000 claims description 2
238000007911 parenteral administration Methods 0.000 claims description 2
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 3
239000008101 lactose Substances 0.000 description 3
238000000034 method Methods 0.000 description 3
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
206010019233 Headaches Diseases 0.000 description 2
RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 description 2
239000003795 chemical substances by application Substances 0.000 description 2
239000012153 distilled water Substances 0.000 description 2
230000001077 hypotensive effect Effects 0.000 description 2
HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
239000011780 sodium chloride Substances 0.000 description 2
239000000126 substance Substances 0.000 description 2
208000024891 symptom Diseases 0.000 description 2
229920002261 Corn starch Polymers 0.000 description 1
208000001953 Hypotension Diseases 0.000 description 1
LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 description 1
208000007101 Muscle Cramp Diseases 0.000 description 1
206010028813 Nausea Diseases 0.000 description 1
208000002193 Pain Diseases 0.000 description 1
208000005392 Spasm Diseases 0.000 description 1
229920002472 Starch Polymers 0.000 description 1
206010047571 Visual impairment Diseases 0.000 description 1
206010047700 Vomiting Diseases 0.000 description 1
230000001154 acute effect Effects 0.000 description 1
239000003708 ampul Substances 0.000 description 1
229940035676 analgesics Drugs 0.000 description 1
239000000730 antalgic agent Substances 0.000 description 1
230000002082 anti-convulsion Effects 0.000 description 1
230000009286 beneficial effect Effects 0.000 description 1
239000011230 binding agent Substances 0.000 description 1
210000004204 blood vessel Anatomy 0.000 description 1
229960001948 caffeine Drugs 0.000 description 1
VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 description 1
150000001875 compounds Chemical class 0.000 description 1
239000012059 conventional drug carrier Substances 0.000 description 1
238000007796 conventional method Methods 0.000 description 1
239000008120 corn starch Substances 0.000 description 1
230000002249 decongestive effect Effects 0.000 description 1
230000003111 delayed effect Effects 0.000 description 1
239000007884 disintegrant Substances 0.000 description 1
230000000694 effects Effects 0.000 description 1
239000012530 fluid Substances 0.000 description 1
230000002496 gastric effect Effects 0.000 description 1
JEGUKCSWCFPDGT-UHFFFAOYSA-N h2o hydrate Chemical compound O.O JEGUKCSWCFPDGT-UHFFFAOYSA-N 0.000 description 1
208000021822 hypotensive Diseases 0.000 description 1
239000004615 ingredient Substances 0.000 description 1
230000002401 inhibitory effect Effects 0.000 description 1
229940102223 injectable solution Drugs 0.000 description 1
238000007917 intracranial administration Methods 0.000 description 1
230000002045 lasting effect Effects 0.000 description 1
239000000314 lubricant Substances 0.000 description 1
235000019359 magnesium stearate Nutrition 0.000 description 1
230000008693 nausea Effects 0.000 description 1
239000000546 pharmaceutical excipient Substances 0.000 description 1
230000003285 pharmacodynamic effect Effects 0.000 description 1
239000003755 preservative agent Substances 0.000 description 1
230000000069 prophylactic effect Effects 0.000 description 1
230000028327 secretion Effects 0.000 description 1
229940125723 sedative agent Drugs 0.000 description 1
239000000932 sedative agent Substances 0.000 description 1
230000001624 sedative effect Effects 0.000 description 1
230000035945 sensitivity Effects 0.000 description 1
230000002048 spasmolytic effect Effects 0.000 description 1
239000003381 stabilizer Substances 0.000 description 1
239000008107 starch Substances 0.000 description 1
235000019698 starch Nutrition 0.000 description 1
230000009182 swimming Effects 0.000 description 1
230000003639 vasoconstrictive effect Effects 0.000 description 1
230000008673 vomiting Effects 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

IL34670A 1969-06-06 1970-06-05 Pharmaceutical preparations containing 2-) 2,6-dichlorophenyl-amino (-1,3-diazacicopentane-) 2) and / or its acidic salt salts IL34670A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE1928798A DE1928798C3 (de)	1969-06-06	1969-06-06	Verwendung von 2-(2,6-Dichlorphenylamino)-1,3-diazacyclopenten-(2)

Publications (2)

Publication Number	Publication Date
IL34670A0 IL34670A0 (en)	1970-08-19
IL34670A true IL34670A (en)	1972-10-29

Family

ID=5736237

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL34670A IL34670A (en)	1969-06-06	1970-06-05	Pharmaceutical preparations containing 2-) 2,6-dichlorophenyl-amino (-1,3-diazacicopentane-) 2) and / or its acidic salt salts

Country Status (11)

Country	Link
US (1)	US3666861A (fr)
AU (1)	AU525754B2 (fr)
BE (1)	BE751577A (fr)
CA (1)	CA943462A (fr)
DE (1)	DE1928798C3 (fr)
FR (1)	FR2052939A1 (fr)
GB (1)	GB1310171A (fr)
IE (1)	IE34728B1 (fr)
IL (1)	IL34670A (fr)
NL (1)	NL161965C (fr)
ZA (1)	ZA703692B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4201211A (en) *	1977-07-12	1980-05-06	Alza Corporation	Therapeutic system for administering clonidine transdermally
US4587257A (en) *	1984-12-14	1986-05-06	Alcon Laboratories, Inc.	Control of ocular bleeding using clonidine derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3236857A (en) *	1961-10-09	1966-02-22	Boehringer Sohn Ingelheim	2-(phenyl-amino)-1, 3-diazacyclopentene-(2) substitution products

1969
- 1969-06-06 DE DE1928798A patent/DE1928798C3/de not_active Expired
1970
- 1970-06-02 ZA ZA703692A patent/ZA703692B/xx unknown
- 1970-06-03 US US43197A patent/US3666861A/en not_active Expired - Lifetime
- 1970-06-04 GB GB2706270A patent/GB1310171A/en not_active Expired
- 1970-06-04 AU AU15931/70A patent/AU525754B2/en not_active Expired
- 1970-06-04 NL NL7008117.A patent/NL161965C/xx not_active IP Right Cessation
- 1970-06-05 CA CA084,759A patent/CA943462A/en not_active Expired
- 1970-06-05 BE BE751577D patent/BE751577A/fr not_active IP Right Cessation
- 1970-06-05 IE IE729/70A patent/IE34728B1/xx unknown
- 1970-06-05 IL IL34670A patent/IL34670A/en unknown
- 1970-06-05 FR FR7020728A patent/FR2052939A1/fr not_active Withdrawn

Also Published As

Publication number	Publication date
NL161965B (nl)	1979-10-15
GB1310171A (en)	1973-03-14
FR2052939A1 (fr)	1971-04-16
CA943462A (en)	1974-03-12
DE1928798B2 (de)	1980-06-19
IE34728L (en)	1970-12-06
DE1928798A1 (de)	1970-12-17
IE34728B1 (en)	1975-08-06
BE751577A (fr)	1970-12-07
IL34670A0 (en)	1970-08-19
NL161965C (nl)	1980-03-17
NL7008117A (fr)	1970-12-08
ZA703692B (en)	1971-02-24
DE1928798C3 (de)	1981-06-11
AU525754B2 (en)	1982-12-02
US3666861A (en)	1972-05-30

Publication	Publication Date	Title
US4435449A (en)	1984-03-06	Treatment of minimal brain dysfunction (MBD)
US4804669A (en)	1989-02-14	Treatment of pain with a piperidine
JPS60105617A (ja)	1985-06-11	骨炎及び骨髄炎予防治療組成物
US4438138A (en)	1984-03-20	Reduction of cholesterol with meta-chloro α-t-butylaminopropiophenone
US4387093A (en)	1983-06-07	Arthritis treatment
US4027017A (en)	1977-05-31	Method of treating alcoholism
IL34670A (en)	1972-10-29	Pharmaceutical preparations containing 2-) 2,6-dichlorophenyl-amino (-1,3-diazacicopentane-) 2) and / or its acidic salt salts
US4650668A (en)	1987-03-17	Composition for relieving toothache pain and other forms of intense pain
US5026706A (en)	1991-06-25	Method for treating dysuria using naftopidil
US3644643A (en)	1972-02-22	Method of reducing intraocular pressure using glycine
US20010029262A1 (en)	2001-10-11	Method of treatment or prophylaxis
JPH08239327A (ja)	1996-09-17	慢性骨格筋疼痛の予防又は治療剤
US4355029A (en)	1982-10-19	Combination therapy for rheumatoid arthritis
KR890014109A (ko)	1989-10-21	의약제
US5081153A (en)	1992-01-14	Sterile parenteral composition
EP0256629A2 (fr)	1988-02-24	Tolrestat ou l'un de ses sels comme médicament immunostimulant
KR20010021796A (ko)	2001-03-15	선택성 세로토닌 재흡수 억제제 (ｓｓｒｉ)를 사용하는심장 질환의 치료 및 예방법
US4302452A (en)	1981-11-24	Use of derivatives of 6α-methylprednisolone as an antiemetic
US4062974A (en)	1977-12-13	Method for treating drepanocytosis
WO2000021534A1 (fr)	2000-04-20	Combinaison pharmaceutique d'ibuprofene-lysine et de domperidone pour traiter la migraine
US4663345A (en)	1987-05-05	Etodolac for treatment of gout
US2995489A (en)	1961-08-08	Method of obtaining preanesthetic sedation and drying with 1-(2-diethylaminoethyl)-5-ethyl-5-phenylbarbituric acid
JP2000229853A (ja)	2000-08-22	生理痛改善用組成物
EP0365134A1 (fr)	1990-04-25	Composé synergique d'agent dopaminergique rénal et d'inhibiteurs d'enzymes de conversion de l'angiotensine
KR960014873B1 (ko)	1996-10-21	제피론을 함유하는 공황(恐慌)장애 경감용 약학 조성물