IL59680A - 7-(((z)-2-(2-aminothiazol-4-yl)-2-(2-carboxy(lower alkyl or cycloalkyl)oxyimino)acetimido)-3-((1-carbamoylmethylpyridinium)thiomethyl)-ceph-3-em-4-carboxylates,their preparation and pharmaceutical compositions comprising them - Google Patents

7-(((z)-2-(2-aminothiazol-4-yl)-2-(2-carboxy(lower alkyl or cycloalkyl)oxyimino)acetimido)-3-((1-carbamoylmethylpyridinium)thiomethyl)-ceph-3-em-4-carboxylates,their preparation and pharmaceutical compositions comprising them

Info

Publication number: IL59680A
Authority: IL; Israel
Prior art keywords: carbamoylmethylpyridinium; acetimido; ceph; aminothiazol; oxyimino
Prior art date: 1979-03-22

Application number

IL59680A

Other languages

English (en)

Other versions

IL59680A0 (en

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-03-22

Filing date

1980-03-21

Publication date

1983-07-31

1980-03-21 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

1980-06-30 Publication of IL59680A0 publication Critical patent/IL59680A0/xx

1983-07-31 Publication of IL59680A publication Critical patent/IL59680A/xx

Links

ZJVYOVDSOZMWFU-UHFFFAOYSA-O 2-pyridin-1-ium-1-ylacetamide Chemical compound NC(=O)C[N+]1=CC=CC=C1 ZJVYOVDSOZMWFU-UHFFFAOYSA-O 0.000 title 1
125000000066 S-methyl group Chemical group [H]C([H])([H])S* 0.000 title 1
125000000217 alkyl group Chemical group 0.000 title 1
125000000753 cycloalkyl group Chemical group 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
- C07D213/20—Quaternary compounds thereof

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Cephalosporin Compounds (AREA)

IL59680A 1979-03-22 1980-03-21 7-(((z)-2-(2-aminothiazol-4-yl)-2-(2-carboxy(lower alkyl or cycloalkyl)oxyimino)acetimido)-3-((1-carbamoylmethylpyridinium)thiomethyl)-ceph-3-em-4-carboxylates,their preparation and pharmaceutical compositions comprising them IL59680A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB7910088		1979-03-22
GB7932982		1979-09-24

Publications (2)

Publication Number	Publication Date
IL59680A0 IL59680A0 (en)	1980-06-30
IL59680A true IL59680A (en)	1983-07-31

Family

ID=26270985

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL59680A IL59680A (en)	1979-03-22	1980-03-21	7-(((z)-2-(2-aminothiazol-4-yl)-2-(2-carboxy(lower alkyl or cycloalkyl)oxyimino)acetimido)-3-((1-carbamoylmethylpyridinium)thiomethyl)-ceph-3-em-4-carboxylates,their preparation and pharmaceutical compositions comprising them

Country Status (18)

Country	Link
US (1)	US4315005A (fr)
CA (1)	CA1144920A (fr)
CH (1)	CH651574A5 (fr)
DE (1)	DE3011038A1 (fr)
DK (1)	DK123480A (fr)
ES (3)	ES8103105A1 (fr)
FI (1)	FI800889A7 (fr)
FR (1)	FR2451921A1 (fr)
IE (1)	IE49569B1 (fr)
IL (1)	IL59680A (fr)
IT (1)	IT1143081B (fr)
LU (1)	LU82285A1 (fr)
NL (1)	NL8001673A (fr)
NO (1)	NO800828L (fr)
NZ (1)	NZ193212A (fr)
PH (1)	PH15777A (fr)
PT (3)	PT70995B (fr)
SE (1)	SE8002217L (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR229882A1 (es) *	1978-05-26	1983-12-30	Glaxo Group Ltd	Procedimiento para preparar antibioticos de cefalosporina
DE2946415A1 (de) *	1978-11-17	1980-05-29	Glaxo Group Ltd	Cephalosporinantibiotika
US4443444A (en) *	1980-08-11	1984-04-17	Fujisawa Pharmaceutical Co., Ltd.	Cephem compounds
GR75487B (fr) *	1981-06-22	1984-07-23	Fujisawa Pharmaceutical Co
FR2516515A1 (fr) *	1981-11-16	1983-05-20	Sanofi Sa	Nouveaux derives de pyridinium thiomethyl cephalosporines, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2517309A1 (fr) *	1981-12-01	1983-06-03	Sanofi Sa	Nouveaux derives de cephalosporines substitues en position 3 par un groupe heterocycle thiomethyl; procede de preparation desdits composes et compositions pharmaceutiques en contenant
US4616081A (en) *	1982-07-07	1986-10-07	Asahi Kasei Kogyo Kabushiki Kaisha	Cephalosporin compounds
AU1278197A (en) *	1995-12-20	1997-07-14	Bristol-Myers Squibb Company	Cephalosporin derivatives

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4033950A (en) *	1971-05-14	1977-07-05	Glaxo Laboratories Limited	3-Hydroxymethyl-7β-(2-alkoxy-or benzyloxyimino-2-arylacetamido)ceph-3-em-4-carboxylic acids and salts thereof
US4095021A (en) *	1973-12-21	1978-06-13	Glaxo Laboratories Limited	3-Carbamoyloxymethyl or N-methyl-carbamoyloxymethyl-7-[2-carboxymethoxyimino-2-(fur-2-yl or thien-2-yl)acetamido]ceph-3-em-4-carboxylic acids and derivatives thereof
US4144392A (en) *	1973-12-21	1979-03-13	Glaxo Laboratories Limited	Cephalosporins having at position-7 a carboxy substituted α-etherified hydroxyimino-arylacetamido group and at position-3 the residue of a sulphur nucleophile
DK154939C (da) *	1974-12-19	1989-06-12	Takeda Chemical Industries Ltd	Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DE2760123C2 (de) *	1976-01-23	1986-04-30	Roussel-Uclaf, Paris	7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
US4166115A (en) *	1976-04-12	1979-08-28	Fujisawa Pharmaceutical Co., Ltd.	Syn 7-oxoimino substituted derivatives of cephalosporanic acid
DE2714880A1 (de) *	1977-04-02	1978-10-26	Hoechst Ag	Cephemderivate und verfahren zu ihrer herstellung
GB1602725A (en)	1977-04-27	1981-11-18	Glaxo Operations Ltd	7-(a-oxyiminoacetamido)-ceph-3-em-4-carboxylic acid derivatives

1980
- 1980-03-21 PT PT70995A patent/PT70995B/pt unknown
- 1980-03-21 CH CH2257/80A patent/CH651574A5/de not_active IP Right Cessation
- 1980-03-21 SE SE8002217A patent/SE8002217L/xx not_active Application Discontinuation
- 1980-03-21 PH PH23792A patent/PH15777A/en unknown
- 1980-03-21 NL NL8001673A patent/NL8001673A/nl not_active Application Discontinuation
- 1980-03-21 US US06/132,644 patent/US4315005A/en not_active Expired - Lifetime
- 1980-03-21 DE DE19803011038 patent/DE3011038A1/de not_active Withdrawn
- 1980-03-21 DK DK123480A patent/DK123480A/da not_active IP Right Cessation
- 1980-03-21 ES ES489783A patent/ES8103105A1/es not_active Expired
- 1980-03-21 LU LU82285A patent/LU82285A1/fr unknown
- 1980-03-21 ES ES489781A patent/ES489781A0/es active Granted
- 1980-03-21 NO NO800828A patent/NO800828L/no unknown
- 1980-03-21 IL IL59680A patent/IL59680A/xx unknown
- 1980-03-21 ES ES489782A patent/ES8103757A1/es not_active Expired
- 1980-03-21 PT PT70994A patent/PT70994B/pt unknown
- 1980-03-21 IE IE593/80A patent/IE49569B1/en unknown
- 1980-03-21 IT IT48230/80A patent/IT1143081B/it active
- 1980-03-21 FI FI800889A patent/FI800889A7/fi not_active Application Discontinuation
- 1980-03-21 PT PT70996A patent/PT70996B/pt unknown
- 1980-03-21 NZ NZ193212A patent/NZ193212A/xx unknown
- 1980-03-24 FR FR8006473A patent/FR2451921A1/fr active Granted
- 1980-03-24 CA CA000348258A patent/CA1144920A/fr not_active Expired

Also Published As

Publication number	Publication date
ES8103101A1 (es)	1981-02-16
ES489783A0 (es)	1981-02-16
IT8048230A0 (it)	1980-03-21
IL59680A0 (en)	1980-06-30
PT70995B (en)	1981-06-25
NZ193212A (en)	1982-12-07
PT70995A (en)	1980-04-01
US4315005A (en)	1982-02-09
SE8002217L (sv)	1980-10-31
NO800828L (no)	1980-09-23
ES8103105A1 (es)	1981-02-16
PT70996B (en)	1981-06-25
LU82285A1 (fr)	1980-10-08
ES489782A0 (es)	1981-03-16
PT70996A (en)	1980-04-01
IE49569B1 (en)	1985-10-30
CH651574A5 (de)	1985-09-30
ES8103757A1 (es)	1981-03-16
IE800593L (en)	1980-09-22
PT70994B (en)	1982-11-22
IT1143081B (it)	1986-10-22
DK123480A (da)	1980-09-23
FR2451921A1 (fr)	1980-10-17
PT70994A (en)	1980-04-01
FI800889A7 (fi)	1981-01-01
CA1144920A (fr)	1983-04-19
FR2451921B1 (fr)	1984-04-27
ES489781A0 (es)	1981-02-16
PH15777A (en)	1983-03-24
DE3011038A1 (de)	1980-11-27
NL8001673A (nl)	1980-09-24

Similar Documents

Publication	Publication Date	Title
IT8224155A0 (it)	1982-11-10	Procedimento per la preparazione di alfa-allumina povera di alcali per scopi ceramici.
FI853632L (fi)	1986-03-25	Nya kolesterolsyntesen inhiberande trans-6-/2-(substituerade pyrrol-1-yl)alkyl/-pyran-2-oner och foerfarande foer deras framstaellning.
IT8223705A0 (it)	1982-10-12	Procedimento per la preparazione di composti cianoeterociclici.
PT71579A (en)	1980-08-01	Process for the preparation of herbicidal sulfonamides andherbicide compositions thereof
PT73391B (en)	1983-06-15	Formulations of heterocyclic compounds
ZA814925B (en)	1983-02-23	Formulations of heterocyclic compounds
AU1527583A (en)	1983-12-08	5-(4-aminophenyl)-2-(1h)-pyrazinones
NO163042C (no)	1990-04-18	Fremgangsm te ved fremstilling av stabiliserte pge2ndelser.
PT72758A (en)	1981-04-01	Process for the preparation of herbicidal compositions comprising tiolcarbamates having extended soil life
IL66887A (en)	1985-09-29	7-(2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido)-3-pyrazinium-1-ylmethyl)-3-cephem-4-carboxylates,their preparation and pharmaceutical preparations comprising them
AU6060180A (en)	1981-01-22	Herbicidal heterocyclic sulphonamides
IL59680A (en)	1983-07-31	7-(((z)-2-(2-aminothiazol-4-yl)-2-(2-carboxy(lower alkyl or cycloalkyl)oxyimino)acetimido)-3-((1-carbamoylmethylpyridinium)thiomethyl)-ceph-3-em-4-carboxylates,their preparation and pharmaceutical compositions comprising them
NO832659L (no)	1984-01-24	Fremgangsmaate for fremstilling av antimikrobielle forbindelser.
IL63531A (en)	1985-07-31	7-beta-(alpha-syn-methoxyiminoalpha-2(2-aminothiazol-4-yl)-acetamido)-3-((1,2,3-thiadiazol-5-ylthio)methyl)-3-cephem-4-carboxylic acids,their preparation and pharmaceutical compositions comprising them
DE3167205D1 (en)	1984-12-20	Pharmaceutical compositions of fungicidal triazole derivatives
RO86246A (fr)	1985-03-15	Procede pour la preparation des 5-(dihydro0ypheno0y)-tetrazoles
IT8122813A0 (it)	1981-07-08	Procedimento di preparazione di n-cicloesilbenzotiazol-2-solfenammi de.
IT8019609A0 (it)	1980-01-31	Procedimento per la preparazione di composti beta-lattamici.
DE3163651D1 (en)	1984-06-20	4-(substituted phenyl)-naphthalen-2(1h)-ones and 2-ols, processes for their preparation, and pharmaceutical compositions containing them
NO824072L (no)	1983-06-06	Fremgangsmaate ved fremstilling av anti-bakterielle p-oxooxazolidinylbenzen-sulfonamider
FI812782A7 (fi)	1982-03-18	Menetelmä bis-tetratsoyylimetyyli- substituoitujen kefalosporiini-antibioottien valmistamiseksi.
IT8020684A0 (it)	1980-03-14	Procedimento per la dealogenazione di eteri.
DE3165808D1 (en)	1984-10-11	Antimicrobial 7-(alpha-acylamino-alpha-arylacetamido)-3-(substituted methyl)cephalosporin compounds, their compositions and production
IT8224536A0 (it)	1982-12-01	Procedimento di preparazione di mononitroclorobenzene.
FI812781A7 (fi)	1982-03-18	Menetelmä bis-tetratsolimetyyli- substituoitujen -laktaami- antibioottien valmistamiseksi.