IL60245A - Oxopiperazinyl analogs of enkephalin,their preparation and pharmaceutical compositions comprising them - Google Patents

Oxopiperazinyl analogs of enkephalin,their preparation and pharmaceutical compositions comprising them

Info

Publication number: IL60245A
Authority: IL; Israel
Prior art keywords: oxopiperazinyl; enkephalin; analogs; preparation; pharmaceutical compositions
Prior art date: 1979-06-21

Application number

IL60245A

Other languages

English (en)

Original Assignee

Richardson Merrell Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-06-21

Filing date

1980-06-06

Publication date

1985-08-30

1980-06-06 Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc

1980-06-06 Priority to IL7078980A priority Critical patent/IL70789A/xx

1980-06-06 Priority to IL7078880A priority patent/IL70788A/xx

1984-01-26 Priority to IL70788A priority patent/IL70788A0/xx

1984-01-26 Priority to IL70789A priority patent/IL70789A0/xx

1985-08-30 Publication of IL60245A publication Critical patent/IL60245A/xx

Links

URLZCHNOLZSCCA-VABKMULXSA-N Leu-enkephalin Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(O)=O)NC(=O)CNC(=O)CNC(=O)[C@@H](N)CC=1C=CC(O)=CC=1)C1=CC=CC=C1 URLZCHNOLZSCCA-VABKMULXSA-N 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
- C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)

IL60245A 1979-06-21 1980-06-06 Oxopiperazinyl analogs of enkephalin,their preparation and pharmaceutical compositions comprising them IL60245A (en)

Priority Applications (4)

Application Number	Priority Date	Filing Date	Title
IL7078980A IL70789A (en)	1979-06-21	1980-06-06	Piperazine derivatives and process for their production
IL7078880A IL70788A (en)	1979-06-21	1980-06-06	Piperazine derivatives and process for their production
IL70788A IL70788A0 (en)	1979-06-21	1984-01-26	Novel piperazine derivatives and process for their production
IL70789A IL70789A0 (en)	1979-06-21	1984-01-26	Novel piperazine derivatives and process for their production

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US5095079A	1979-06-21	1979-06-21
US06/130,431 US4341698A (en)	1979-06-21	1980-03-14	Enkaphalin derivatives
AU91877/82A AU559278B2 (en)	1979-06-21	1982-12-24	Piperazines

Publications (1)

Publication Number	Publication Date
IL60245A true IL60245A (en)	1985-08-30

Family

ID=36764304

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL60245A IL60245A (en)	1979-06-21	1980-06-06	Oxopiperazinyl analogs of enkephalin,their preparation and pharmaceutical compositions comprising them

Country Status (17)

Country	Link
US (1)	US4341698A (de)
AU (1)	AU559278B2 (de)
CA (1)	CA1161838A (de)
CH (2)	CH648835A5 (de)
DE (1)	DE3022401A1 (de)
DK (1)	DK265780A (de)
ES (1)	ES492566A0 (de)
FR (2)	FR2459236A1 (de)
GB (3)	GB2051821B (de)
IE (1)	IE49834B1 (de)
IL (1)	IL60245A (de)
IT (1)	IT1148277B (de)
NL (1)	NL8003580A (de)
NO (1)	NO801855L (de)
NZ (1)	NZ193934A (de)
PH (1)	PH19222A (de)
SE (3)	SE447250B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6194435B1 (en)	1996-10-11	2001-02-27	Cor Therapeutics, Inc.	Lactams as selective factor Xa inhibitors
US6262047B1 (en)	1996-10-11	2001-07-17	Cor Therapeutics, Inc.	Selective factor Xa inhibitors
US6369080B2 (en)	1996-10-11	2002-04-09	Cor Therapeutics, Inc.	Selective factor Xa inhibitors
US6063794A (en)	1996-10-11	2000-05-16	Cor Therapeutics Inc.	Selective factor Xa inhibitors
EP0977772A1 (de)	1997-04-14	2000-02-09	Cor Therapeutics, Inc.	Selektive faktor xa-inhibitoren
US6133256A (en) *	1997-04-14	2000-10-17	Cor Therapeutics Inc	Selective factor Xa inhibitors
US6369063B1 (en)	1997-04-14	2002-04-09	Cor Therapeutics, Inc.	Selective factor Xa inhibitors
US6228854B1 (en)	1997-08-11	2001-05-08	Cor Therapeutics, Inc.	Selective factor Xa inhibitors
US6333321B1 (en)	1997-08-11	2001-12-25	Cor Therapeutics, Inc.	Selective factor Xa inhibitors
US6218382B1 (en)	1997-08-11	2001-04-17	Cor Therapeutics, Inc	Selective factor Xa inhibitors
CN104922117A (zh)	2005-03-22	2015-09-23	阿泽范药品公司	用于治疗月经前病症的β-内酰氨基链烷酸
CA2615813C (en) *	2005-07-19	2015-12-15	Azevan Pharmaceuticals, Inc.	Beta-lactamyl phenylalanine, cysteine, and serine vasopressin antagonists
US7964181B2 (en) *	2006-03-30	2011-06-21	Palatin Technologies, Inc.	Amino acid surrogates for peptidic constructs
US8114844B2 (en) *	2006-03-30	2012-02-14	Palatin Technologies, Inc.	Linear and cyclic melanocortin receptor-specific peptidomimetics
AU2007233123A1 (en) *	2006-03-30	2007-10-11	Palatin Technologies, Inc.	Linear natriuretic peptide constructs
EA200802060A1 (ru) *	2006-03-30	2009-10-30	Палатин Текнолоджиз, Инк.	Суррогаты аминокислот для пептидных конструктов
US8580746B2 (en)	2006-03-30	2013-11-12	Palatin Technologies, Inc.	Amide linkage cyclic natriuretic peptide constructs
AU2007233116B2 (en) *	2006-03-30	2013-05-09	Palatin Technologies, Inc.	Cyclic natriuretic peptide constructs
PT2354124E (pt) *	2006-12-19	2013-04-09	Hoffmann La Roche	Derivados de heteroaril-pirrolidinilo e piperidinil-cetona
MX2010013447A (es) *	2008-06-18	2010-12-22	Hoffmann La Roche	Aril-cetonas como inhibidores de reabsorcion de monoaminas.
AU2011272738B2 (en)	2010-07-01	2015-08-20	Azevan Pharmaceuticals, Inc.	Methods for treating post traumatic stress disorder
BR112016022575A2 (pt)	2014-03-28	2017-08-15	Azevan Pharmaceuticals Inc	Composições e métodos para o tratamento de doenças neurodegenerativas
KR102790657B1 (ko)	2017-09-15	2025-04-02	아제반 파마슈티칼스, 인코퍼레이티드	뇌 손상을 치료하기 위한 조성물 및 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2604845A1 (de) *	1976-02-07	1977-08-18	Knoll Ag	Neue piperazinderivate
US4254107A (en) *	1979-11-27	1981-03-03	Merck & Co., Inc.	Long-lasting agonists of enkephalin

1980
- 1980-03-14 US US06/130,431 patent/US4341698A/en not_active Expired - Lifetime
- 1980-06-04 NZ NZ193934A patent/NZ193934A/xx unknown
- 1980-06-04 IE IE1152/80A patent/IE49834B1/en not_active IP Right Cessation
- 1980-06-04 CA CA000353383A patent/CA1161838A/en not_active Expired
- 1980-06-06 IL IL60245A patent/IL60245A/xx unknown
- 1980-06-06 SE SE8004254A patent/SE447250B/sv not_active IP Right Cessation
- 1980-06-14 DE DE19803022401 patent/DE3022401A1/de not_active Withdrawn
- 1980-06-16 PH PH24144A patent/PH19222A/en unknown
- 1980-06-17 CH CH1248/84A patent/CH648835A5/de not_active IP Right Cessation
- 1980-06-17 CH CH469880A patent/CH645363A5/de not_active IP Right Cessation
- 1980-06-18 GB GB8019903A patent/GB2051821B/en not_active Expired
- 1980-06-18 ES ES492566A patent/ES492566A0/es active Granted
- 1980-06-20 IT IT49032/80A patent/IT1148277B/it active
- 1980-06-20 NO NO801855A patent/NO801855L/no unknown
- 1980-06-20 DK DK265780A patent/DK265780A/da not_active Application Discontinuation
- 1980-06-20 NL NL8003580A patent/NL8003580A/nl not_active Application Discontinuation
- 1980-06-20 FR FR8013795A patent/FR2459236A1/fr active Granted
1981
- 1981-02-04 FR FR8102171A patent/FR2473042A1/fr active Granted
1982
- 1982-09-10 GB GB08225842A patent/GB2106515B/en not_active Expired
- 1982-09-10 GB GB08225828A patent/GB2132605B/en not_active Expired
- 1982-12-24 AU AU91877/82A patent/AU559278B2/en not_active Ceased
1985
- 1985-02-22 SE SE8500877A patent/SE460540B/sv not_active IP Right Cessation
- 1985-02-22 SE SE8500878A patent/SE460541B/sv not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU559278B2 (en)	1987-03-05
AU9187782A (en)	1983-04-21
NO801855L (no)	1980-12-22
SE8500878D0 (sv)	1985-02-22
GB2132605B (en)	1985-01-03
GB2051821B (en)	1983-04-27
FR2459236A1 (fr)	1981-01-09
SE460540B (sv)	1989-10-23
GB2106515B (en)	1983-11-23
FR2473042A1 (fr)	1981-07-10
FR2473042B1 (de)	1983-07-01
NZ193934A (en)	1983-02-15
CH648835A5 (de)	1985-04-15
SE447250B (sv)	1986-11-03
CH645363A5 (de)	1984-09-28
SE8500877L (sv)	1985-02-22
SE8500877D0 (sv)	1985-02-22
ES8105720A1 (es)	1981-06-16
GB2106515A (en)	1983-04-13
SE8004254L (sv)	1980-12-22
GB2132605A (en)	1984-07-11
GB2051821A (en)	1981-01-21
DE3022401A1 (de)	1981-01-08
IE49834B1 (en)	1985-12-25
US4341698A (en)	1982-07-27
IE801152L (en)	1980-12-21
IT8049032A0 (it)	1980-06-20
IT1148277B (it)	1986-11-26
FR2459236B1 (de)	1984-01-06
ES492566A0 (es)	1981-06-16
DK265780A (da)	1980-12-22
CA1161838A (en)	1984-02-07
PH19222A (en)	1986-02-12
NL8003580A (nl)	1980-12-23
SE460541B (sv)	1989-10-23

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