IL67040A - N-nitroso-n-(beta-chloro ethyl)-carbamoyl peptides,their preparation and pharmaceutical compositions comprising them - Google Patents

N-nitroso-n-(beta-chloro ethyl)-carbamoyl peptides,their preparation and pharmaceutical compositions comprising them

Info

Publication number: IL67040A
Authority: IL; Israel
Prior art keywords: preparation; nitroso; carbamoyl; peptides; beta
Prior art date: 1981-10-22

Application number

IL67040A

Other languages

English (en)

Other versions

IL67040A0 (en

Original Assignee

Chinoin Gyogyszer Es Vegyeszet

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-10-22

Filing date

1982-10-21

Publication date

1985-11-29

1982-10-21 Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet

1983-02-23 Publication of IL67040A0 publication Critical patent/IL67040A0/xx

1985-11-29 Publication of IL67040A publication Critical patent/IL67040A/xx

Links

239000008194 pharmaceutical composition Substances 0.000 title 1
102000004196 processed proteins & peptides Human genes 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 title 1
102000015636 Oligopeptides Human genes 0.000 abstract 2
108010038807 Oligopeptides Proteins 0.000 abstract 2
125000003277 amino group Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 1
IVHKZGYFKJRXBD-UHFFFAOYSA-N amino carbamate Chemical compound NOC(N)=O IVHKZGYFKJRXBD-UHFFFAOYSA-N 0.000 abstract 1
230000000259 anti-tumor effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/595—Gastrins; Cholecystokinins [CCK]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/68—Melanocyte-stimulating hormone [MSH]
- C07K14/685—Alpha-melanotropin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/695—Corticotropin [ACTH]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Toxicology (AREA)
Zoology (AREA)
Endocrinology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Hematology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

IL67040A 1981-10-22 1982-10-21 N-nitroso-n-(beta-chloro ethyl)-carbamoyl peptides,their preparation and pharmaceutical compositions comprising them IL67040A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU813073A HU187461B (en)	1981-10-22	1981-10-22	Process for producing n-nitrozo-n-bracket-beta-chloroethyl-bracket closed-carbamoyl-peptides of citostatic activity

Publications (2)

Publication Number	Publication Date
IL67040A0 IL67040A0 (en)	1983-02-23
IL67040A true IL67040A (en)	1985-11-29

Family

ID=10962415

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL67040A IL67040A (en)	1981-10-22	1982-10-21	N-nitroso-n-(beta-chloro ethyl)-carbamoyl peptides,their preparation and pharmaceutical compositions comprising them

Country Status (11)

Country	Link
US (1)	US4950651A (de)
EP (1)	EP0078167B1 (de)
JP (1)	JPS5888349A (de)
AT (1)	ATE32342T1 (de)
DE (1)	DE3278075D1 (de)
DK (1)	DK468482A (de)
FI (1)	FI77672C (de)
GR (1)	GR76768B (de)
HU (1)	HU187461B (de)
IL (1)	IL67040A (de)
SU (3)	SU1424739A3 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6057367A (en)	1996-08-30	2000-05-02	Duke University	Manipulating nitrosative stress to kill pathologic microbes, pathologic helminths and pathologically proliferating cells or to upregulate nitrosative stress defenses
RU2268070C2 (ru) *	2004-04-01	2006-01-20	Юрий Сергеевич Сидоренко	Способ профилактики опухолевой болезни в эксперименте
GB0918579D0 (en)	2009-10-22	2009-12-09	Imp Innovations Ltd	Gadd45beta targeting agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3814746A (en) *	1970-08-05	1974-06-04	Inst Sieroterapico Milanese Se	Mannich base of tetracycline and polypeptides

1981
- 1981-10-22 HU HU813073A patent/HU187461B/hu not_active IP Right Cessation
1982
- 1982-10-20 FI FI823591A patent/FI77672C/fi not_active IP Right Cessation
- 1982-10-21 DK DK468482A patent/DK468482A/da not_active Application Discontinuation
- 1982-10-21 GR GR69590A patent/GR76768B/el unknown
- 1982-10-21 IL IL67040A patent/IL67040A/xx unknown
- 1982-10-22 EP EP82305633A patent/EP0078167B1/de not_active Expired
- 1982-10-22 JP JP57184802A patent/JPS5888349A/ja active Pending
- 1982-10-22 SU SU823506053A patent/SU1424739A3/ru active
- 1982-10-22 DE DE8282305633T patent/DE3278075D1/de not_active Expired
- 1982-10-22 AT AT82305633T patent/ATE32342T1/de not_active IP Right Cessation
1983
- 1983-06-20 SU SU833605466A patent/SU1414851A1/ru active
1984
- 1984-01-31 SU SU843697502A patent/SU1586520A3/ru active
1985
- 1985-04-19 US US06/725,146 patent/US4950651A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
FI77672C (fi)	1989-04-10
GR76768B (de)	1984-09-03
FI823591A0 (fi)	1982-10-20
DE3278075D1 (de)	1988-03-10
DK468482A (da)	1983-04-23
SU1586520A3 (ru)	1990-08-15
FI77672B (fi)	1988-12-30
EP0078167A1 (de)	1983-05-04
HU187461B (en)	1986-01-28
JPS5888349A (ja)	1983-05-26
IL67040A0 (en)	1983-02-23
ATE32342T1 (de)	1988-02-15
SU1414851A1 (ru)	1988-08-07
US4950651A (en)	1990-08-21
SU1424739A3 (ru)	1988-09-15
EP0078167B1 (de)	1988-02-03
FI823591L (fi)	1983-04-23

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