IL74264A - Preparation of calciferol derivatives,certain such novel compounds and pharmaceutical compositions containing them - Google Patents

Preparation of calciferol derivatives,certain such novel compounds and pharmaceutical compositions containing them

Info

Publication number
IL74264A
IL74264A IL74264A IL7426485A IL74264A IL 74264 A IL74264 A IL 74264A IL 74264 A IL74264 A IL 74264A IL 7426485 A IL7426485 A IL 7426485A IL 74264 A IL74264 A IL 74264A
Authority
IL
Israel
Prior art keywords
preparation
certain
pharmaceutical compositions
compositions containing
novel compounds
Prior art date
Application number
IL74264A
Other languages
English (en)
Other versions
IL74264A0 (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL74264A0 publication Critical patent/IL74264A0/xx
Publication of IL74264A publication Critical patent/IL74264A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/22—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
    • C07C35/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings
    • C07C35/32—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings the condensed ring system being a (4.3.0) system, e.g. indenols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/20—Free hydroxyl or mercaptan
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/26—Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL74264A 1984-02-08 1985-02-06 Preparation of calciferol derivatives,certain such novel compounds and pharmaceutical compositions containing them IL74264A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57816084A 1984-02-08 1984-02-08
US68212584A 1984-12-17 1984-12-17

Publications (2)

Publication Number Publication Date
IL74264A0 IL74264A0 (en) 1985-05-31
IL74264A true IL74264A (en) 1988-08-31

Family

ID=27077449

Family Applications (1)

Application Number Title Priority Date Filing Date
IL74264A IL74264A (en) 1984-02-08 1985-02-06 Preparation of calciferol derivatives,certain such novel compounds and pharmaceutical compositions containing them

Country Status (10)

Country Link
EP (1) EP0154185B1 (da)
JP (1) JPH0735365B2 (da)
AU (1) AU575373B2 (da)
CA (1) CA1311501C (da)
DE (1) DE3565401D1 (da)
DK (1) DK157244C (da)
IE (1) IE57917B1 (da)
IL (1) IL74264A (da)
NZ (1) NZ211071A (da)
PH (1) PH19845A (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL77668A (en) * 1986-01-21 1989-03-31 Teva Pharma Production of cholecalciferol derivatives and novel intermediates used therefor
GB2229921B (en) * 1989-04-05 1992-12-16 Chugai Pharmaceutical Co Ltd Treatment for hyperparathyroidism with use of vitamin d derivatives
CA2062520C (en) * 1991-03-11 1998-08-11 Hector F. Deluca Synthesis of 1-alpha-hydroxy-secosterol compounds
AU650751B2 (en) * 1991-05-28 1994-06-30 Wisconsin Alumni Research Foundation Novel synthesis of 19-nor vitamin D compounds
US5300705A (en) * 1993-03-18 1994-04-05 Hoffmann-La Roche Inc. Process for the preparation of 1α,25,26-trihydroxy-22-ene-cholecalciferol
JP4752110B2 (ja) * 2000-12-25 2011-08-17 住友化学株式会社 トリフルオロプロペニル化合物の製造法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4069321A (en) * 1975-10-14 1978-01-17 Merck & Co., Inc. Blocked cholecalciferol and dihydrotachysterol 3 derivatives
CA1206882A (en) * 1982-02-12 1986-07-02 Hoffmann-La Roche Limited Use of cholecalciferol derivatives
EP0086350A3 (de) * 1982-02-12 1984-11-28 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Herstellung von Cholesterinderivaten
JPS58210017A (ja) * 1982-05-31 1983-12-07 Kureha Chem Ind Co Ltd 抗腫瘍剤
ATE90564T1 (de) * 1982-06-30 1993-07-15 Gen Hospital Corp Vitamin d glycoside.
DE3471928D1 (en) * 1983-01-28 1988-07-14 Hoffmann La Roche Process for the preparation of cholecalciferol derivatives

Also Published As

Publication number Publication date
EP0154185B1 (en) 1988-10-05
IE850298L (en) 1985-08-08
DE3565401D1 (de) 1988-11-10
IL74264A0 (en) 1985-05-31
JPS60248664A (ja) 1985-12-09
DK53785D0 (da) 1985-02-06
DK157244C (da) 1990-04-23
CA1311501C (en) 1992-12-15
PH19845A (en) 1986-07-22
AU575373B2 (en) 1988-07-28
EP0154185A1 (en) 1985-09-11
DK53785A (da) 1985-08-09
DK157244B (da) 1989-11-27
NZ211071A (en) 1988-04-29
AU3846985A (en) 1985-08-15
IE57917B1 (en) 1993-05-19
JPH0735365B2 (ja) 1995-04-19

Similar Documents

Publication Publication Date Title
IL78079A0 (en) Sulphonylaminoethyl compounds,their preparation and pharmaceutical compositions containing them
IL90066A0 (en) Preparation of vitamin-d compounds,certain such compounds and pharmaceutical compositions containing them
IL75586A (en) Pharmaceutical compositions containing indole-2-alkanoic acids and derivatives thereof,and certain such novel compounds
IL82421A0 (en) Pharmaceutical compositions containing heterocyclic compounds,certain such novel compounds and their preparation
IL76133A0 (en) Bicyclic compounds,their preparation and pharmaceutical compositions containing them
PT83594A (en) Process for preparation of insecticidal n:-substituted-n,n:-diacyllhydrazines and of insecticidal compositions containing the same
IL70656A0 (en) Pharmaceutical compositions containing phenothiazone derivatives and analogs thereof and certain such novel compounds
IL72471A0 (en) Pharmaceutical compositions containing phenylquinoline-carboxylic acids and derivatives thereof,certain such novel compounds and their preparation
IL75794A0 (en) Aminophenol compounds,their preparation and pharmaceutical compositions containing them
PT81502A (en) Process for the preparation of cholecalciferol derivatives and of pharmaceutical compositions containing the same
PT80794A (en) Process for the preparation of novel isoindolinyl-alkyl-piperazines and of pharmaceutical compositions containing the same
ZA862141B (en) Substituted 1,8-naphthyridinones,processes for their preparation and pharmaceutical compositions containing them
IL81410A (en) Pharmaceutical compositions containing substituted n-arylmethylamine derivatives,certain such novel compounds and their preparation
IL75720A0 (en) Morpholinol compounds,their preparation and pharmaceutical compositions containing them
IL91862A0 (en) Pharmaceutical compositions containing certain saccharides,some such novel compounds and their preparation
DE3377212D1 (en) New substituted derivatives of 2,5-diamino 1,4-diazole, preparation methods thereof and pharmaceutical compositions containing them
DE3573428D1 (en) Novel delta4- and delta5- androstene derivatives, processes for their preparation and pharmaceutical compositions containing these derivatives
IL76312A (en) Xenocoumacins and derivatives thereof,their preparation and pharmaceutical compositions containing them
IL70508A (en) Pharmaceutical compositions containing aralkyltriazole derivatives,some such novel compounds and their preparation
IL74264A0 (en) Preparation of calciferol derivatives,certain such novel compounds and pharmaceutical compositions containing them
IL77055A0 (en) Polycyclic compounds,their preparation and pharmaceutical compositions containing them
IL75913A0 (en) Phenyl-nonatetraenoic acid derivatives,their preparation and pharmaceutical compositions containing them
PT81083A (en) Process for the preparation of substituted 7-oxomitosanes and of pharmaceutical compositions containing the same
IL75824A0 (en) Pharmaceutical compositions containing 4h-1,4-benzothiazines,their preparation and certain such novel compounds
IL72831A0 (en) 2-aminomethyl-penem compounds,their preparation and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
KB Patent renewed
RH1 Patent not in force