IL74707A - Anti-viral compositions comprising pyridazinamines,certain such novel compounds and their preparation - Google Patents

Anti-viral compositions comprising pyridazinamines,certain such novel compounds and their preparation

Info

Publication number: IL74707A
Authority: IL; Israel
Prior art keywords: pyridazinamines; preparation; certain; novel compounds; viral compositions
Prior art date: 1984-03-26

Application number

IL74707A

Other languages

English (en)

Other versions

IL74707A0 (en

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-03-26

Filing date

1985-03-25

Publication date

1988-05-31

1985-03-25 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

1985-06-30 Publication of IL74707A0 publication Critical patent/IL74707A0/xx

1988-05-31 Publication of IL74707A publication Critical patent/IL74707A/xx

Links

150000001875 compounds Chemical class 0.000 title abstract 3
239000000203 mixture Substances 0.000 title abstract 2
230000000840 anti-viral effect Effects 0.000 title 1
LETVJWLLIMJADE-UHFFFAOYSA-N pyridazin-3-amine Chemical class NC1=CC=CN=N1 LETVJWLLIMJADE-UHFFFAOYSA-N 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
239000003443 antiviral agent Substances 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/22—Nitrogen and oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Virology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicinal Preparation (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

IL74707A 1984-03-26 1985-03-25 Anti-viral compositions comprising pyridazinamines,certain such novel compounds and their preparation IL74707A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US59344484A	1984-03-26	1984-03-26
US06/702,772 US5001125A (en)	1984-03-26	1985-02-15	Anti-virally active pyridazinamines

Publications (2)

Publication Number	Publication Date
IL74707A0 IL74707A0 (en)	1985-06-30
IL74707A true IL74707A (en)	1988-05-31

Family

ID=27081705

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL74707A IL74707A (en)	1984-03-26	1985-03-25	Anti-viral compositions comprising pyridazinamines,certain such novel compounds and their preparation

Country Status (22)

Country	Link
US (3)	US5001125A (fr)
EP (1)	EP0156433B1 (fr)
KR (1)	KR870001158B1 (fr)
AT (1)	ATE61050T1 (fr)
AU (1)	AU576563B2 (fr)
BG (1)	BG43690A3 (fr)
CA (1)	CA1238321A (fr)
CZ (1)	CZ277730B6 (fr)
DE (1)	DE3581819D1 (fr)
DK (1)	DK166277C (fr)
ES (1)	ES8606289A1 (fr)
FI (1)	FI85373C (fr)
GR (1)	GR850714B (fr)
HU (1)	HU198010B (fr)
IL (1)	IL74707A (fr)
NO (1)	NO161257C (fr)
NZ (1)	NZ211494A (fr)
PH (1)	PH22495A (fr)
PT (1)	PT80157B (fr)
RO (1)	RO91197B (fr)
SU (1)	SU1384198A3 (fr)
ZW (1)	ZW5485A1 (fr)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
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1985
- 1985-02-15 US US06/702,772 patent/US5001125A/en not_active Expired - Fee Related
- 1985-02-28 KR KR1019850001303A patent/KR870001158B1/ko not_active Expired
- 1985-03-15 EP EP85200384A patent/EP0156433B1/fr not_active Expired - Lifetime
- 1985-03-15 DE DE8585200384T patent/DE3581819D1/de not_active Expired - Fee Related
- 1985-03-15 AT AT85200384T patent/ATE61050T1/de not_active IP Right Cessation
- 1985-03-18 NZ NZ211494A patent/NZ211494A/en unknown
- 1985-03-20 CZ CS851952A patent/CZ277730B6/cs unknown
- 1985-03-21 GR GR850714A patent/GR850714B/el unknown
- 1985-03-22 ES ES541521A patent/ES8606289A1/es not_active Expired
- 1985-03-22 NO NO851167A patent/NO161257C/no unknown
- 1985-03-22 SU SU853867689A patent/SU1384198A3/ru active
- 1985-03-25 AU AU40348/85A patent/AU576563B2/en not_active Ceased
- 1985-03-25 PT PT80157A patent/PT80157B/pt not_active IP Right Cessation
- 1985-03-25 FI FI851177A patent/FI85373C/fi not_active IP Right Cessation
- 1985-03-25 CA CA000477330A patent/CA1238321A/fr not_active Expired
- 1985-03-25 HU HU851127A patent/HU198010B/hu not_active IP Right Cessation
- 1985-03-25 DK DK134185A patent/DK166277C/da active
- 1985-03-25 IL IL74707A patent/IL74707A/xx unknown
- 1985-03-25 ZW ZW54/85A patent/ZW5485A1/xx unknown
- 1985-03-26 BG BG069434A patent/BG43690A3/xx unknown
- 1985-03-26 RO RO118137A patent/RO91197B/ro unknown
- 1985-03-26 PH PH32047A patent/PH22495A/en unknown
1991
- 1991-01-03 US US07/637,091 patent/US5157035A/en not_active Expired - Fee Related
1992
- 1992-08-13 US US07/929,622 patent/US5292738A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
HUT37614A (en)	1986-01-23
RO91197A (fr)	1987-06-30
EP0156433A3 (en)	1986-07-23
HU198010B (en)	1989-07-28
FI851177L (fi)	1985-09-27
RO91197B (ro)	1987-07-01
KR850006401A (ko)	1985-10-05
ES8606289A1 (es)	1986-04-16
FI85373C (fi)	1992-04-10
CA1238321A (fr)	1988-06-21
GR850714B (fr)	1985-06-14
AU4034885A (en)	1985-10-03
CS195285A3 (en)	1992-11-18
FI851177A0 (fi)	1985-03-25
ES541521A0 (es)	1986-04-16
ZW5485A1 (en)	1986-10-22
BG43690A3 (en)	1988-07-15
US5157035A (en)	1992-10-20
PH22495A (en)	1988-09-12
EP0156433A2 (fr)	1985-10-02
NZ211494A (en)	1988-05-30
DE3581819D1 (de)	1991-04-04
PT80157B (en)	1987-03-20
DK134185D0 (da)	1985-03-25
ATE61050T1 (de)	1991-03-15
CZ277730B6 (en)	1993-04-14
US5001125A (en)	1991-03-19
PT80157A (en)	1985-04-01
FI85373B (fi)	1991-12-31
DK166277C (da)	1993-08-30
AU576563B2 (en)	1988-09-01
KR870001158B1 (ko)	1987-06-13
DK134185A (da)	1985-09-27
NO851167L (no)	1985-09-27
NO161257C (no)	1989-07-26
DK166277B (da)	1993-03-29
US5292738A (en)	1994-03-08
EP0156433B1 (fr)	1991-02-27
SU1384198A3 (ru)	1988-03-23
NO161257B (no)	1989-04-17
IL74707A0 (en)	1985-06-30

Publication	Publication Date	Title
IL74707A0 (en)	1985-06-30	Anti-viral compositions comprising pyridazinamines,certain such novel compounds and their preparation
ES8603870A1 (es)	1986-01-01	Un procedimiento para la preparacion de derivados de 2,2'-iminobisetanol.
ES8307794A1 (es)	1983-08-01	Un procedimiento para la preparacion de agentes antifugicos triazolicos.
GB2143734B (en)	1986-07-30	Process for the preparation of sustained release pharmaceutical compositions having a high active ingredient content
JO1502B1 (en)	1989-01-25	New pharmacy vehicles
EP0279149A3 (en)	1988-08-31	Benzimidazole derivatives, process for their production and a pharmaceutical composition containing the same
FI945452A0 (fi)	1994-11-21	Ibuprofeenia sisältävä poreileva lääkevalmiste sekä sen valmistusmenetelmä
HUT50334A (en)	1990-01-29	Process for producing arylpiperazinyl-alkilenephenyl-p-heterocycluc compounds, pharmaceutically acceptable acid addition salts thereof and pharmaceutical compositions comprising the compounds as active ingredient
GR852395B (fr)	1985-12-03
GB2021409A (en)	1979-12-05	Pharmaceutical composition
IE56229B1 (en)	1991-05-22	2-piperazinyl-or-homopiperazinyl-quinazoline derivatives their production and pharmaceutical compositions containing them
HU896342D0 (en)	1990-02-28	Process for the preparation of benzohydroxane acid derivatives and herbicides compositions containing them as active ingredients
ES8304924A1 (es)	1983-03-16	Un procedimiento para la preparacion de nuevos derivados del acido glutamil-diaminopimelico que contiene una b-lactama.
ES8502439A1 (es)	1985-01-01	Un metodo de preparar una forma solida, estable y soluble en agua de 3-desazaguanina
JO1519B1 (en)	1989-01-25	New compounds (new benzimidazole derivatives are effective as ulcers)
JO1531B1 (en)	1989-01-25	New near-compounds
IT8420315A0 (it)	1984-03-30	Derivati dell'acido 3-mercapto-2-oxo-1-pirrolidinacetico, procedimento di preparazione e composizioni farmaceutiche che licontengono.
PH21595A (en)	1987-12-11	Process for the preparation of sustained release pharmaceutical compositions having a high active ingredient content
IT8222500A0 (it)	1982-07-21	Derivati dell'acido 7 bet5a-amino-3-metossi-3-cefem-4-carbossilico,procedimenti per la loro preparazione e composizioni farmaceutiche che licontengono.