IL75984A0 - Angiotensine-ii analogues substituted in the 1-,5-and 8-positions,their preparation and pharmaceutical compositions containing them - Google Patents

Angiotensine-ii analogues substituted in the 1-,5-and 8-positions,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL75984A0
IL75984A0 IL75984A IL7598485A IL75984A0 IL 75984 A0 IL75984 A0 IL 75984A0 IL 75984 A IL75984 A IL 75984A IL 7598485 A IL7598485 A IL 7598485A IL 75984 A0 IL75984 A0 IL 75984A0
Authority
IL
Israel
Prior art keywords
angiotensine
positions
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL75984A
Other languages
English (en)
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of IL75984A0 publication Critical patent/IL75984A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/14—Angiotensins: Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IL75984A 1984-08-02 1985-08-01 Angiotensine-ii analogues substituted in the 1-,5-and 8-positions,their preparation and pharmaceutical compositions containing them IL75984A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU842944A HU191961B (en) 1984-08-02 1984-08-02 Process for producing 1,5 and 8 substituted peptides of angiotenzin-ii antagonistic activity

Publications (1)

Publication Number Publication Date
IL75984A0 true IL75984A0 (en) 1985-12-31

Family

ID=10961797

Family Applications (1)

Application Number Title Priority Date Filing Date
IL75984A IL75984A0 (en) 1984-08-02 1985-08-01 Angiotensine-ii analogues substituted in the 1-,5-and 8-positions,their preparation and pharmaceutical compositions containing them

Country Status (9)

Country Link
US (1) US4672054A (fr)
EP (1) EP0171270A3 (fr)
JP (1) JPS6143199A (fr)
AU (1) AU4571185A (fr)
DK (1) DK350985A (fr)
ES (1) ES8606405A1 (fr)
FI (1) FI852976A7 (fr)
HU (1) HU191961B (fr)
IL (1) IL75984A0 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4772684A (en) * 1987-01-20 1988-09-20 Triton Biosciences, Inc. Peptides affecting blood pressure regulation
EP0284510A3 (fr) * 1987-03-24 1990-08-22 Asahi Breweries, Ltd. N-[N alpha-(1(S)-carboxy-3-cyclohexylpropyl)-L-lysyl]-N-cyclopentylglycine en tant qu'antihypertenseurs
US6759384B1 (en) 1994-04-26 2004-07-06 Aventis Pharmaceuticals Inc. Factor Xa inhibitors
ZA953361B (en) * 1994-04-26 1996-01-12 Selectide Corp Factor Xa inhibitors
US5849510A (en) * 1994-04-26 1998-12-15 Selectide Corporation Factor Xa inhibitors

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3751404A (en) * 1971-02-12 1973-08-07 Morton Norwich Products Inc L-prolyl-l-arginyl-l-volyl-l-tyrosyl-l-volyl-l-histidyl-l-prolyl-glycine
US3923771A (en) * 1974-05-10 1975-12-02 Francis Merlin Bumpus N-Guanidylacetyl-{8 des-asp{hu 1{b -Ile{hu 8{b {9 {0 angiotensin II as an angiotensin antagonist
US3925345A (en) * 1974-05-10 1975-12-09 Francis Merlin Bumpus (sar' 1',thr' 8'+9 angiotensin ii as an angiotensin antagonist
US3923770A (en) * 1974-05-10 1975-12-02 Francis Merlin Bumpus {8 Me{hd 2{b Gly{hu 1{b , Ile{hu 8{b {9 -Anziotensin II as an angiotensin antagonist
US3915946A (en) * 1974-06-20 1975-10-28 Francis Merlin Bumpus Des-asp{hu 1{b -ala{hu 8 {b angiotensin II as a specific inhibotor for the release of aldosterone
US3915948A (en) * 1974-08-05 1975-10-28 Morton Norwich Products Inc Sarcosyl-L-arginyl-L-valyl-L-tyrosyl-L-valyl-L-histidyl-L-proline
DE2457463A1 (de) * 1974-12-05 1976-06-10 Hoechst Ag Neue peptide mit blutdrucksenkender wirkung und verfahren zu ihrer herstellung
US3976770A (en) * 1975-02-10 1976-08-24 Francis Merlin Bumpus Sar'-(OMe)Thr8 Angiotensin II as an angiotensin II antagonist
HU177134B (en) * 1977-07-18 1981-07-28 Richter Gedeon Vegyeszet Process for preparing angiotensin ii analogues containing alpha-hydroxy-acid in position 1 with angiotensin ii antagonist activity
HU177133B (en) * 1977-07-18 1981-07-28 Richter Gedeon Vegyeszet Process for preparing angiotensin ii analogues containing alpha- amino-oxy-acid in position 1 with angiotensin ii antagonist activity
US4204991A (en) * 1977-10-25 1980-05-27 G. D. Searle & Co. Sarcosine1 dehydroalanine8 angiotensin II derivatives
HU181009B (en) * 1980-01-18 1983-05-30 Richter Gedeon Vegyeszet Process for preparing angiotensin-ii analogues with antagonictic activity containing in position 1 sarcosyl,hydroxyacetyl or l-alpha-aminoxy-propionyl group and in positiona 8 esteric group
FR2540501A1 (fr) * 1983-02-07 1984-08-10 Inst Organicheskogo Sinteza Ak Nouvel analogue cyclique de l'angiotensine constitue par la cyclo (1e-8)-/lysi/angiotensine

Also Published As

Publication number Publication date
HU191961B (en) 1987-04-28
EP0171270A3 (fr) 1988-01-07
DK350985D0 (da) 1985-08-01
FI852976L (fi) 1986-02-03
FI852976A7 (fi) 1986-02-03
US4672054A (en) 1987-06-09
JPS6143199A (ja) 1986-03-01
FI852976A0 (fi) 1985-08-01
ES545868A0 (es) 1986-04-01
EP0171270A2 (fr) 1986-02-12
HUT38106A (en) 1986-04-28
AU4571185A (en) 1986-02-06
DK350985A (da) 1986-02-03
ES8606405A1 (es) 1986-04-01

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