IL77584A - Method and apparatus for enzymatic synthesis - Google Patents

Method and apparatus for enzymatic synthesis

Info

Publication number: IL77584A
Authority: IL; Israel
Prior art keywords: product; enzymatic synthesis; synthetic; arte; equilibria
Prior art date: 1985-01-15

Application number

IL77584A

Other languages

English (en)

Original Assignee

Genentech Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-01-15

Filing date

1986-01-13

Publication date

1989-10-31

1986-01-13 Application filed by Genentech Inc filed Critical Genentech Inc

1989-10-31 Publication of IL77584A publication Critical patent/IL77584A/xx

Links

238000000034 method Methods 0.000 title abstract 2
230000015572 biosynthetic process Effects 0.000 title 1
230000002255 enzymatic effect Effects 0.000 title 1
238000003786 synthesis reaction Methods 0.000 title 1
239000000047 product Substances 0.000 abstract 3
YZQCXOFQZKCETR-UWVGGRQHSA-N Asp-Phe Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(O)=O)CC1=CC=CC=C1 YZQCXOFQZKCETR-UWVGGRQHSA-N 0.000 abstract 1
125000005907 alkyl ester group Chemical group 0.000 abstract 1
239000006227 byproduct Substances 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
238000000909 electrodialysis Methods 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
238000011084 recovery Methods 0.000 abstract 1
231100000331 toxic Toxicity 0.000 abstract 1
230000002588 toxic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
- C07K5/0613—Aspartame

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Molecular Biology (AREA)
Wood Science & Technology (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biotechnology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Microbiology (AREA)
Biophysics (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Apparatus Associated With Microorganisms And Enzymes (AREA)

IL77584A 1985-01-15 1986-01-13 Method and apparatus for enzymatic synthesis IL77584A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US69168985A	1985-01-15	1985-01-15

Publications (1)

Publication Number	Publication Date
IL77584A true IL77584A (en)	1989-10-31

Family

ID=24777560

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL77584A IL77584A (en)	1985-01-15	1986-01-13	Method and apparatus for enzymatic synthesis

Country Status (10)

Country	Link
EP (1)	EP0188342B1 (da)
JP (1)	JPS61205490A (da)
AT (1)	ATE76096T1 (da)
AU (1)	AU598452B2 (da)
CA (1)	CA1309681C (da)
DE (1)	DE3685223D1 (da)
DK (1)	DK16286A (da)
IE (1)	IE58291B1 (da)
IL (1)	IL77584A (da)
ZA (1)	ZA86269B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5202235A (en) *	1986-08-18	1993-04-13	The Coca-Cola Company	Enzymatic method for the synthesis and separation of peptides
US5336601A (en) *	1986-08-18	1994-08-09	The Coca-Cola Company	Enzymatic membrane method for the snythesis and separation of peptides
US5002871A (en) *	1986-08-18	1991-03-26	The Coca-Cola Company	Enzymatic membrane method for the synthesis and separation of peptides
US5037741A (en) *	1986-08-18	1991-08-06	The Coca Cola Company	Enzymatic method for the synthesis and separation of peptides
US5350681A (en) *	1986-08-18	1994-09-27	The Coca-Cola Company	Enzymatic membrane method for the synthesis and separation of peptides
CA2054754A1 (en) *	1989-04-24	1990-10-25	Daniel J. Brose	Enzymatic membrane method for the synthesis and separation of peptides
US5714465A (en)	1989-05-19	1998-02-03	Amgen Inc.	Method of inhibiting tumor cell dissemination with a metalloproteinase inhibitor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH490305A (fr) *	1967-03-28	1970-05-15	Politechnika Slaska Im Wincent	Procédé de fabrication d'acides carboxyliques
JPS52136985A (en) *	1976-05-07	1977-11-16	Ajinomoto Co Inc	Fermentation and dialysis
US4506011A (en) *	1981-09-05	1985-03-19	Toyo Soda Manufacturing Co., Ltd.	Process for preparation of aspartylphenylalanine alkyl esters

1986
- 1986-01-13 AT AT86300161T patent/ATE76096T1/de active
- 1986-01-13 IL IL77584A patent/IL77584A/xx not_active IP Right Cessation
- 1986-01-13 AU AU52225/86A patent/AU598452B2/en not_active Expired
- 1986-01-13 EP EP86300161A patent/EP0188342B1/en not_active Expired - Lifetime
- 1986-01-13 DE DE8686300161T patent/DE3685223D1/de not_active Expired - Lifetime
- 1986-01-14 ZA ZA86269A patent/ZA86269B/xx unknown
- 1986-01-14 JP JP61006132A patent/JPS61205490A/ja active Pending
- 1986-01-14 IE IE10286A patent/IE58291B1/en not_active IP Right Cessation
- 1986-01-14 DK DK16286A patent/DK16286A/da not_active Application Discontinuation
- 1986-01-15 CA CA000499619A patent/CA1309681C/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CA1309681C (en)	1992-11-03
DK16286D0 (da)	1986-01-14
DK16286A (da)	1986-07-16
JPS61205490A (ja)	1986-09-11
EP0188342A2 (en)	1986-07-23
DE3685223D1 (de)	1992-06-17
ZA86269B (en)	1987-09-30
ATE76096T1 (de)	1992-05-15
EP0188342B1 (en)	1992-05-13
AU598452B2 (en)	1990-06-28
IE860102L (en)	1986-07-15
IE58291B1 (en)	1993-08-25
AU5222586A (en)	1986-07-24
EP0188342A3 (en)	1988-03-30

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Legal Events

Date	Code	Title
1996-03-31	KB	Patent renewed
2000-07-16	FF	Patent granted
2000-08-31	KB	Patent renewed
2004-02-19	KB	Patent renewed
2006-04-10	EXP	Patent expired