IL78531A0 - Recombinant dna expression vectors and dna compounds which encode isopenicillin n synthetase - Google Patents

Recombinant dna expression vectors and dna compounds which encode isopenicillin n synthetase

Info

Publication number
IL78531A0
IL78531A0 IL78531A IL7853186A IL78531A0 IL 78531 A0 IL78531 A0 IL 78531A0 IL 78531 A IL78531 A IL 78531A IL 7853186 A IL7853186 A IL 7853186A IL 78531 A0 IL78531 A0 IL 78531A0
Authority
IL
Israel
Prior art keywords
synthetase
expression vectors
dna
compounds
recombinant dna
Prior art date
Application number
IL78531A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL78531A0 publication Critical patent/IL78531A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C12N15/69—Increasing the copy number of the vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL78531A 1985-04-22 1986-04-17 Recombinant dna expression vectors and dna compounds which encode isopenicillin n synthetase IL78531A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72587085A 1985-04-22 1985-04-22
US79938485A 1985-11-18 1985-11-18

Publications (1)

Publication Number Publication Date
IL78531A0 true IL78531A0 (en) 1986-08-31

Family

ID=27111238

Family Applications (1)

Application Number Title Priority Date Filing Date
IL78531A IL78531A0 (en) 1985-04-22 1986-04-17 Recombinant dna expression vectors and dna compounds which encode isopenicillin n synthetase

Country Status (14)

Country Link
EP (1) EP0200425B1 (fr)
JP (1) JPH0787788B2 (fr)
KR (1) KR860008287A (fr)
CN (1) CN86102604A (fr)
AU (2) AU592791B2 (fr)
BG (2) BG45047A3 (fr)
CA (1) CA1309673C (fr)
DE (1) DE3683080D1 (fr)
DK (1) DK178386A (fr)
ES (3) ES8800344A1 (fr)
FI (1) FI95810C (fr)
HU (1) HU202279B (fr)
IE (1) IE58780B1 (fr)
IL (1) IL78531A0 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK170476B1 (da) 1980-04-03 1995-09-11 Biogen Inc Rekombinant DNA-molekyle, uni-cellulær vært transformeret med mindst ét rekombinant DNA-molekyle, fremgangsmåde til transformering af en uni-cellulær vært, samt fremgangsmåder til fremstilling af et polpeptid, der udviser den immunologiske eller biologiske aktivitet af human beta-interferon
GB8508800D0 (en) * 1985-04-04 1985-05-09 Glaxo Group Ltd Microbiological process
US4892819A (en) * 1985-11-25 1990-01-09 Eli Lilly And Company Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from penicillium chrysogenum
EP0233715B1 (fr) * 1986-01-31 1994-05-25 BEECHAM GROUP plc Isolement et expression de gènes impliqués dans la biosynthèse de bêta-lactames
CA1327170C (fr) * 1987-03-04 1994-02-22 Stephen Wyatt Queener Vecteurs recombinants d'expression de l'adn et composes de l'adn en codant la desacetoxycephalosporine c synthetase et la desacetylcephalosporine c synthetase
GB2208077A (en) * 1987-04-24 1989-02-22 Antibioticos Sa Isopenicillin n synthetase gene derived from aspergillus nidulans
EP0303364A1 (fr) * 1987-08-10 1989-02-15 The Governors of the University of Alberta Clonage et détermination de la séquence nucléotide du gène isopénicilline-N-synthétase de streptomyces clavuligerus
US4885252A (en) * 1987-09-08 1989-12-05 Eli Lilly And Company Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from aspergillus nidulans
US4950603A (en) * 1987-11-02 1990-08-21 Eli Lilly And Company Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from Streptomyces lipmanii
GB8728811D0 (en) * 1987-12-09 1988-01-27 Beecham Group Plc Novel substance
US6258555B1 (en) 1987-12-09 2001-07-10 Beecham Group P.L.C. DNA encoding ACV synthetase
KR0171897B1 (ko) * 1989-12-27 1999-02-01 후지사와 도모끼찌로 7-아미노세펨 화합물 또는 그 염류의 제조 방법
ES2133140T3 (es) * 1990-01-12 1999-09-01 Glaxo Group Ltd Secuencia de adn que codifica una enzima de biosintesis de antibioticos.
WO1996010084A1 (fr) * 1994-09-28 1996-04-04 Novo Nordisk A/S Procede de production de metabolites secondaires
DE19755302A1 (de) * 1997-12-12 1999-06-17 Hoechst Marion Roussel De Gmbh Neuer Transkriptionsfaktor CPCR1 zur Regulation des Isopenicillin N-Synthetase-Gens (pcbC) und des AC-/ACV-Synthetase-Gens (pcbAB)
EP1165546A2 (fr) * 1999-04-02 2002-01-02 Du Pont Pharmaceuticals Company Nouveaux inhibiteurs de lactame de metalloproteases matricielles, de tnf-alpha, et de l'aggrecanase

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3330003A1 (de) * 1982-10-21 1984-10-31 Gesellschaft für Biotechnologische Forschung mbH (GBF), 3300 Braunschweig Dna-sequenz und dna-strukturen und sie verwendendes verfahren zur herstellung von penicillin-acylase
CA1278540C (fr) * 1983-07-22 1991-01-02 Eli Lilly And Company Gene modifie conferant une resistance a un antibiotique
US4762786A (en) * 1984-09-27 1988-08-09 Eli Lilly And Company Vectors and conditions which allow genetic transformation of cephalosporium
GB8508800D0 (en) * 1985-04-04 1985-05-09 Glaxo Group Ltd Microbiological process
US4892819A (en) * 1985-11-25 1990-01-09 Eli Lilly And Company Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from penicillium chrysogenum

Also Published As

Publication number Publication date
AU592791B2 (en) 1990-01-25
DK178386A (da) 1986-10-23
ES554218A0 (es) 1987-11-01
IE861029L (en) 1986-10-22
HU202279B (en) 1991-02-28
CN86102604A (zh) 1986-11-26
AU4234789A (en) 1990-01-11
JPH0787788B2 (ja) 1995-09-27
AU619596B2 (en) 1992-01-30
JPS61254192A (ja) 1986-11-11
EP0200425A2 (fr) 1986-11-05
ES557658A0 (es) 1988-08-16
BG45047A3 (bg) 1989-03-15
ES557829A0 (es) 1989-01-16
FI861653A0 (fi) 1986-04-18
HUT40705A (en) 1987-01-28
CA1309673C (fr) 1992-11-03
EP0200425B1 (fr) 1991-12-27
ES8900142A1 (es) 1989-01-16
FI95810C (fi) 1996-03-25
ES8800344A1 (es) 1987-11-01
DE3683080D1 (de) 1992-02-06
FI95810B (fi) 1995-12-15
IE58780B1 (en) 1993-11-17
DK178386D0 (da) 1986-04-18
EP0200425A3 (en) 1988-07-06
KR860008287A (ko) 1986-11-14
FI861653A7 (fi) 1986-10-23
BG45219A3 (bg) 1989-04-14
AU5643186A (en) 1986-10-30
ES8802585A1 (es) 1988-08-16

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