IL80538A - Pharmaceutical composition having thrombolytic activity - Google Patents

Pharmaceutical composition having thrombolytic activity

Info

Publication number: IL80538A
Authority: IL; Israel
Prior art keywords: pharmaceutical composition; thrombolytic activity; plasminogen activators; type; thrombolytic
Prior art date: 1985-11-11

Application number

IL80538A

Other languages

English (en)

Other versions

IL80538A0 (en

Original Assignee

Leuven Res & Dev Vzw

Collen Desire Jose

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-11-11

Filing date

1986-11-07

Publication date

1991-06-30

1986-11-07 Application filed by Leuven Res & Dev Vzw, Collen Desire Jose filed Critical Leuven Res & Dev Vzw

1987-02-27 Publication of IL80538A0 publication Critical patent/IL80538A0/xx

1991-06-30 Publication of IL80538A publication Critical patent/IL80538A/xx

Links

239000008194 pharmaceutical composition Substances 0.000 title abstract 2
230000002537 thrombolytic effect Effects 0.000 title 1
102000001938 Plasminogen Activators Human genes 0.000 abstract 2
108010001014 Plasminogen Activators Proteins 0.000 abstract 2
229940127126 plasminogen activator Drugs 0.000 abstract 2
239000003527 fibrinolytic agent Substances 0.000 abstract 1
238000001727 in vivo Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
230000002195 synergetic effect Effects 0.000 abstract 1
229960000103 thrombolytic agent Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/49—Urokinase; Tissue plasminogen activator
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Gastroenterology & Hepatology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Hematology (AREA)
Diabetes (AREA)
Biomedical Technology (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Epidemiology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

IL80538A 1985-11-11 1986-11-07 Pharmaceutical composition having thrombolytic activity IL80538A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
NL8503097A NL8503097A (nl)	1985-11-11	1985-11-11	Geneesmiddel met thrombolytische werking.

Publications (2)

Publication Number	Publication Date
IL80538A0 IL80538A0 (en)	1987-02-27
IL80538A true IL80538A (en)	1991-06-30

Family

ID=19846844

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL80538A IL80538A (en)	1985-11-11	1986-11-07	Pharmaceutical composition having thrombolytic activity

Country Status (17)

Country	Link
EP (1)	EP0223192B1 (de)
JP (1)	JPH089546B2 (de)
AT (1)	ATE64532T1 (de)
AU (1)	AU586713B2 (de)
CA (1)	CA1303987C (de)
DE (1)	DE3679887D1 (de)
DK (1)	DK164640C (de)
ES (1)	ES2039194T3 (de)
GR (1)	GR3002226T3 (de)
HU (1)	HU196715B (de)
IE (1)	IE59387B1 (de)
IL (1)	IL80538A (de)
NL (1)	NL8503097A (de)
NZ (1)	NZ218231A (de)
PH (1)	PH23192A (de)
PT (1)	PT83721B (de)
ZA (1)	ZA868464B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8623823D0 (en) *	1986-10-03	1986-11-05	Sandoz Ltd	Therapeutic lysis of fibrin blood clots
SE462829B (sv) *	1989-01-10	1990-09-10	Kabigen Ab	Trombolytiskt aktiva kompositioner innehaallande en modifierad plasminogenaktivator av vaevnadstyp samt en normal human t-pa, streptokinas eller humant urokinas
WO1990014078A1 (en) *	1989-05-17	1990-11-29	Research Corporation Technologies, Inc.	Method and composition for the treatment of thrombosis in a mammal
GB8919803D0 (en) *	1989-09-01	1989-10-18	Ciba Geigy	Pharmaceutical compositions

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1642612A1 (de) *	1967-03-02	1971-09-09	Bayer Ag	Die Verwendung von Erythrozyten zur Gewinnung bzw.Isolierung eines Plasminogen-Aktivators
NL8003402A (nl) *	1980-06-11	1982-01-04	Leuven Res & Dev Vzw	Nieuwe plasminogeen-activator en farmaceutisch preparaat met trombolytische werking.
SU1662352A3 (ru) *	1982-05-05	1991-07-07	Генентек, Инк (Фирма)	Штамм бактерий ЕSснеRIснIа coLI - продуцент активатора плазминогена тканевого типа
JPS5951220A (ja) *	1982-08-02	1984-03-24	Asahi Chem Ind Co Ltd	新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤
JPH0637398B2 (ja) *	1982-10-29	1994-05-18	三井東圧化学株式会社	血栓溶解剤
JPS59139323A (ja) *	1983-01-28	1984-08-10	Green Cross Corp:The	ウロキナ−ゼ乾燥製剤
JPS6051119A (ja) *	1983-08-30	1985-03-22	Green Cross Corp:The	ウロキナ−ゼ乾燥製剤
JPS60152421A (ja) *	1984-01-23	1985-08-10	Sanwa Kagaku Kenkyusho:Kk	ヒト胎盤性プラスミノ−ゲン活性化因子、及びそれとヒトプラスミノ−ゲン活性化阻害因子との結合物、及びそれらの製法
GB8430253D0 (en) *	1984-11-30	1985-01-09	Beecham Group Plc	Compounds
JPH0610139B2 (ja) *	1986-05-15	1994-02-09	エモリユニバーシティ	繊維素溶解性合成物混合物及び血管内の血餅溶解用薬剤
NL8702234A (nl) *	1986-10-03	1988-05-02	Sandoz Ag	Verbeteringen aan of met betrekking tot organische verbindingen.

1985
- 1985-11-11 NL NL8503097A patent/NL8503097A/nl not_active Application Discontinuation
1986
- 1986-11-06 ZA ZA868464A patent/ZA868464B/xx unknown
- 1986-11-07 DK DK532886A patent/DK164640C/da not_active IP Right Cessation
- 1986-11-07 IL IL80538A patent/IL80538A/xx unknown
- 1986-11-10 PH PH34452A patent/PH23192A/en unknown
- 1986-11-10 CA CA000522568A patent/CA1303987C/en not_active Expired - Lifetime
- 1986-11-10 NZ NZ218231A patent/NZ218231A/xx unknown
- 1986-11-10 AU AU65031/86A patent/AU586713B2/en not_active Ceased
- 1986-11-10 IE IE296286A patent/IE59387B1/en not_active IP Right Cessation
- 1986-11-11 ES ES198686115665T patent/ES2039194T3/es not_active Expired - Lifetime
- 1986-11-11 PT PT83721A patent/PT83721B/pt not_active IP Right Cessation
- 1986-11-11 AT AT86115665T patent/ATE64532T1/de not_active IP Right Cessation
- 1986-11-11 HU HU864649A patent/HU196715B/hu not_active IP Right Cessation
- 1986-11-11 EP EP86115665A patent/EP0223192B1/de not_active Expired - Lifetime
- 1986-11-11 JP JP61269506A patent/JPH089546B2/ja not_active Expired - Lifetime
- 1986-11-11 DE DE8686115665T patent/DE3679887D1/de not_active Expired - Lifetime
1991
- 1991-07-02 GR GR91400921T patent/GR3002226T3/el unknown

Also Published As

Publication number	Publication date
GR3002226T3 (en)	1992-12-30
EP0223192B1 (de)	1991-06-19
IE862962L (en)	1987-05-11
PT83721A (en)	1986-12-01
AU586713B2 (en)	1989-07-20
JPS62155222A (ja)	1987-07-10
DK532886D0 (da)	1986-11-07
HUT43794A (en)	1987-12-28
CA1303987C (en)	1992-06-23
PH23192A (en)	1989-05-29
IL80538A0 (en)	1987-02-27
NZ218231A (en)	1988-10-28
AU6503186A (en)	1987-05-14
ES2039194T3 (es)	1993-09-16
DE3679887D1 (de)	1991-07-25
JPH089546B2 (ja)	1996-01-31
NL8503097A (nl)	1987-06-01
HU196715B (en)	1989-01-30
ZA868464B (en)	1987-06-24
EP0223192A1 (de)	1987-05-27
PT83721B (pt)	1988-08-17
ATE64532T1 (de)	1991-07-15
DK164640C (da)	1992-12-14
DK532886A (da)	1987-05-12
DK164640B (da)	1992-07-27
IE59387B1 (en)	1994-02-23

Legal Events

Date	Code	Title	Description
1997-03-18	KB	Patent renewed

Publication	Publication Date	Title
IL80659A0 (en)	1987-02-27	Modified tissue plasminogen activators,their preparation and pharmaceutical compositions containing them
ZA897173B (en)	1990-09-26	Pharmaceutically active combination
EP0041766A3 (en)	1981-12-30	New plasminogen activator and pharmaceutical composition having thrombolytic activity
EP0196920A3 (en)	1988-07-27	Degraded species of tissue-type plasminogen activator, pharmaceutical composition and method of preparation
NZ216306A (en)	1989-10-27	Pharmaceutical compositions containing tissue plasminogen activator
IL78938A (en)	1993-02-21	Pharmaceutical composition containing lyophilized tissue plasminogen activator and its preparation
NZ220260A (en)	1990-07-26	Synergistic combination of t-pa and sod and pharmaceutical formulation
NZ219829A (en)	1990-05-28	Tissue-type plasminogen activator modified in the region of amino acids 67-69 and pharmaceutical compositions thereof
EP0136464A3 (en)	1985-07-03	Therapeutic compositions for oral use containing stable s-adenosy1-l-methionine salts
GR3002226T3 (en)	1992-12-30	Pharmaceutical composition having thrombolytic activity
IL91774A0 (en)	1990-06-10	Preparation of plasminogen activator expressed in prokaryotes
EP0158880A3 (en)	1986-01-08	Liposomes with inhalable allergens for treatment of allergies, method for their preparation and pharmaceutical compositions containing them
ES8704903A1 (es)	1987-04-16	Un metodo para preparar 6-cloro-2-metil-1h-2,3,4,5-tetrahidro-3-benzazepen-n-oxido.
DE69000290D1 (de)	1992-10-15	Thrombotische zusammensetzungen.
NZ223291A (en)	1990-09-26	Modified tissue-type plasminogen activator
IE860355L (en)	1986-08-09	Modified tissue-type plasminogen activator
IE883342L (en)	1989-05-06	Human tissue-type plasminogen activator variant