IL81209A - Substituted 6h-indolo(2,3-b)-quinoxalines,their preparation and pharmaceutical compositions comprising them - Google Patents
Substituted 6h-indolo(2,3-b)-quinoxalines,their preparation and pharmaceutical compositions comprising themInfo
- Publication number
- IL81209A IL81209A IL81209A IL8120987A IL81209A IL 81209 A IL81209 A IL 81209A IL 81209 A IL81209 A IL 81209A IL 8120987 A IL8120987 A IL 8120987A IL 81209 A IL81209 A IL 81209A
- Authority
- IL
- Israel
- Prior art keywords
- indolo
- quinoxalines
- substituted
- preparation
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8600260A SE8600260D0 (sv) | 1986-01-21 | 1986-01-21 | Substituerade indolokinoxaliner |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL81209A0 IL81209A0 (en) | 1987-08-31 |
| IL81209A true IL81209A (en) | 1991-04-15 |
Family
ID=20363170
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL81209A IL81209A (en) | 1986-01-21 | 1987-01-08 | Substituted 6h-indolo(2,3-b)-quinoxalines,their preparation and pharmaceutical compositions comprising them |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4990510A (de) |
| EP (1) | EP0238459B1 (de) |
| JP (1) | JPH07107066B2 (de) |
| KR (1) | KR880700801A (de) |
| AP (1) | AP27A (de) |
| AT (1) | ATE74920T1 (de) |
| AU (1) | AU606047B2 (de) |
| CA (1) | CA1303613C (de) |
| DE (1) | DE3778190D1 (de) |
| DK (1) | DK492587A (de) |
| ES (1) | ES2037105T3 (de) |
| FI (1) | FI883373A7 (de) |
| HU (1) | HU201937B (de) |
| IL (1) | IL81209A (de) |
| NO (1) | NO873945D0 (de) |
| OA (1) | OA08744A (de) |
| RU (1) | RU1776259C (de) |
| SE (1) | SE8600260D0 (de) |
| WO (1) | WO1987004436A1 (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8600261D0 (sv) * | 1986-01-21 | 1986-01-21 | Lundblad Leif | Indolokinoxaliner med substituenter i 6-position som innehaller cykliska grupper |
| AU673258B2 (en) * | 1993-04-22 | 1996-10-31 | Taisho Pharmaceutical Co., Ltd. | Indolo(2,3-b)quinoxaline derivative |
| US5700823A (en) * | 1994-01-07 | 1997-12-23 | Sugen, Inc. | Treatment of platelet derived growth factor related disorders such as cancers |
| SE504289C2 (sv) * | 1994-06-23 | 1996-12-23 | Leif J I Lundblad | Användning av vissa indolo-2,3b-kinoxaliner för framställning av ett läkemedel för inhibering av enzymet HIV-integras |
| SE504862C2 (sv) * | 1994-12-27 | 1997-05-20 | Leif J I Lundblad | Användning av vissa indolo-§2,3b¤-kinoxaliner för framställning av ett läkemedel för skydd av DNA i initieringsfasen och/eller promotionsfasen av karcinogenes och för förhindrande av oxidativ stress i patienter med sjukdomar relaterade till fria radikaler |
| US5721277A (en) * | 1995-04-21 | 1998-02-24 | Sugen, Inc. | Compounds and methods for inhibiting hyper-proliferative cell growth |
| US6331555B1 (en) | 1995-06-01 | 2001-12-18 | University Of California | Treatment of platelet derived growth factor related disorders such as cancers |
| US6465466B1 (en) | 1995-12-22 | 2002-10-15 | Leif J. I. Lundblad | Uses of indolo-2 [2,3b] -quinoxalines |
| US6316479B1 (en) | 1997-05-19 | 2001-11-13 | Sugen, Inc. | Isoxazole-4-carboxamide compounds active against protein tryosine kinase related disorders |
| SE9704723D0 (sv) * | 1997-12-17 | 1997-12-17 | Leif J I Lundblad | Ligands |
| SE516067C2 (sv) * | 2000-02-18 | 2001-11-12 | Lundblad Leif J I | Användning av en förening för framställning av ett läkemedel |
| US6333327B2 (en) * | 2000-02-18 | 2001-12-25 | Leif J. I. Lundblad | Method for the treatment of Multiple Sclerosis |
| GB0022922D0 (en) * | 2000-09-19 | 2000-11-01 | Chapman Robert E | Compounds for use in medicine |
| SE529777C2 (sv) * | 2006-01-23 | 2007-11-20 | Vironova Ab | Nya föreningar och användning därav |
| DE602008001795D1 (de) | 2008-04-30 | 2010-08-26 | Univ Duisburg Essen | IndolÄ2,3-bÜ-, IndenÄ1,2-bÜ- und IndenÄ2,1-bÜpyridoÄ2,3-fÜ Quinoxalin-3-Carboxylsäuren und Ester, Verfahren zu ihrer Herstellung und ihre Verwendung als Antivirus- und Antitumormittel |
| EP2489354A1 (de) * | 2011-02-18 | 2012-08-22 | Vironova AB | Pharmazeutische Formulierung enthaltend B220 zur topischen Behandlung von Herpes |
| CN105061432B (zh) * | 2015-07-16 | 2017-09-29 | 河北大学 | 6H‑吲哚[2,3‑b]喹喔啉衍生物、药物组合物及其制备和应用 |
| KR20230022880A (ko) | 2020-06-10 | 2023-02-16 | 사익손 아베 | 라벡시모드의 결정성 형태를 포함하는 경구 제형 |
| WO2022002898A1 (en) | 2020-06-29 | 2022-01-06 | Vironova Medical Ab | 6h-indolo(2,3-b)quinoxaline derivatives useful in therapy in particular in a virus infection |
| EP4171561A1 (de) | 2020-06-29 | 2023-05-03 | Vironova Medical AB | In der therapie verwendbare 6h-indolo[2,3-b chinoxalinderivate |
| CN117865962A (zh) * | 2023-12-11 | 2024-04-12 | 江南大学 | 一类新型吲哚二酮及吲哚并喹喔啉类衍生物荧光化合物及其制备方法和用途 |
-
1986
- 1986-01-21 SE SE8600260A patent/SE8600260D0/xx unknown
-
1987
- 1987-01-08 IL IL81209A patent/IL81209A/xx not_active IP Right Cessation
- 1987-01-09 AP APAP/P/1987/000055A patent/AP27A/en active
- 1987-01-19 AU AU68995/87A patent/AU606047B2/en not_active Ceased
- 1987-01-19 WO PCT/SE1987/000019 patent/WO1987004436A1/en not_active Ceased
- 1987-01-19 ES ES198787850012T patent/ES2037105T3/es not_active Expired - Lifetime
- 1987-01-19 JP JP62500757A patent/JPH07107066B2/ja not_active Expired - Fee Related
- 1987-01-19 HU HU847A patent/HU201937B/hu not_active IP Right Cessation
- 1987-01-19 EP EP87850012A patent/EP0238459B1/de not_active Expired - Lifetime
- 1987-01-19 AT AT87850012T patent/ATE74920T1/de not_active IP Right Cessation
- 1987-01-19 DE DE8787850012T patent/DE3778190D1/de not_active Expired - Lifetime
- 1987-01-19 US US07/102,147 patent/US4990510A/en not_active Expired - Lifetime
- 1987-01-20 CA CA000527660A patent/CA1303613C/en not_active Expired - Lifetime
- 1987-09-18 DK DK492587A patent/DK492587A/da not_active Application Discontinuation
- 1987-09-21 NO NO873945A patent/NO873945D0/no unknown
- 1987-09-21 KR KR870700852A patent/KR880700801A/ko not_active Withdrawn
-
1988
- 1988-07-15 FI FI883373A patent/FI883373A7/fi not_active Application Discontinuation
- 1988-07-19 RU SU884356314A patent/RU1776259C/ru active
- 1988-07-21 OA OA59390A patent/OA08744A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0238459B1 (de) | 1992-04-15 |
| RU1776259C (ru) | 1992-11-15 |
| ATE74920T1 (de) | 1992-05-15 |
| WO1987004436A1 (en) | 1987-07-30 |
| DK492587D0 (da) | 1987-09-18 |
| AU6899587A (en) | 1987-08-14 |
| EP0238459A1 (de) | 1987-09-23 |
| NO873945L (no) | 1987-09-21 |
| DK492587A (da) | 1987-09-18 |
| NO873945D0 (no) | 1987-09-21 |
| IL81209A0 (en) | 1987-08-31 |
| HU201937B (en) | 1991-01-28 |
| JPS63502588A (ja) | 1988-09-29 |
| DE3778190D1 (de) | 1992-05-21 |
| AU606047B2 (en) | 1991-01-31 |
| US4990510A (en) | 1991-02-05 |
| CA1303613C (en) | 1992-06-16 |
| KR880700801A (ko) | 1988-04-12 |
| HUT47937A (en) | 1989-04-28 |
| SE8600260D0 (sv) | 1986-01-21 |
| AP27A (en) | 1988-12-02 |
| AP8700055A0 (en) | 1986-11-01 |
| FI883373A0 (fi) | 1988-07-15 |
| JPH07107066B2 (ja) | 1995-11-15 |
| OA08744A (en) | 1989-03-31 |
| ES2037105T3 (es) | 1993-06-16 |
| FI883373A7 (fi) | 1988-07-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| EXP | Patent expired |