IL83269A - 2,5-disubstituted oxazolidine or imidazolidine-4-one-3-yl azetidin-2-one derivatives and their preparation - Google Patents
2,5-disubstituted oxazolidine or imidazolidine-4-one-3-yl azetidin-2-one derivatives and their preparationInfo
- Publication number
- IL83269A IL83269A IL83269A IL8326987A IL83269A IL 83269 A IL83269 A IL 83269A IL 83269 A IL83269 A IL 83269A IL 8326987 A IL8326987 A IL 8326987A IL 83269 A IL83269 A IL 83269A
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- azetidin
- imidazolidine
- derivatives
- disubstituted
- Prior art date
Links
- -1 2,5-disubstituted oxazolidine Chemical class 0.000 title abstract 2
- ZZOCUNXJWLFLLO-UHFFFAOYSA-N 3-(2-oxoazetidin-1-yl)imidazolidin-4-one Chemical class N1CN(C(C1)=O)N1C(CC1)=O ZZOCUNXJWLFLLO-UHFFFAOYSA-N 0.000 title 1
- AODGNVSBNVOVPQ-UHFFFAOYSA-N 2-(5-oxoimidazolidin-1-yl)acetyl chloride Chemical class ClC(=O)CN1CNCC1=O AODGNVSBNVOVPQ-UHFFFAOYSA-N 0.000 abstract 1
- 150000004705 aldimines Chemical class 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- MNFORVFSTILPAW-UHFFFAOYSA-N azetidin-2-one Chemical class O=C1CCN1 MNFORVFSTILPAW-UHFFFAOYSA-N 0.000 abstract 1
- 238000006352 cycloaddition reaction Methods 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/888,895 US4772694A (en) | 1986-07-24 | 1986-07-24 | Chiral 3-(1,2,5-trisubstituted imidazolidinone) azetidinone antibiotic intermediates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL83269A true IL83269A (en) | 1991-12-15 |
Family
ID=25394125
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL83269A IL83269A (en) | 1986-07-24 | 1987-07-21 | 2,5-disubstituted oxazolidine or imidazolidine-4-one-3-yl azetidin-2-one derivatives and their preparation |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4772694A (de) |
| EP (1) | EP0254578B1 (de) |
| JP (1) | JPH0757752B2 (de) |
| KR (1) | KR960000048B1 (de) |
| AT (1) | ATE94165T1 (de) |
| CA (1) | CA1308725C (de) |
| DE (1) | DE3787333T2 (de) |
| ES (1) | ES2059384T3 (de) |
| HU (1) | HU197741B (de) |
| IL (1) | IL83269A (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4870169A (en) * | 1985-07-17 | 1989-09-26 | President And Fellows Of Harvard College | Intermediates for beta-lactam antibiotics |
| JPH0733254B2 (ja) * | 1990-02-27 | 1995-04-12 | ソブエクレー株式会社 | 活性水酸化マグネシウムの製造方法 |
| WO1997030707A1 (en) * | 1996-02-23 | 1997-08-28 | Eli Lilly And Company | NON-PEPTIDYL VASOPRESSIN V1a ANTAGONISTS |
| US5957712A (en) * | 1997-07-30 | 1999-09-28 | Thomas & Betts International, Inc. | Loadbreak connector assembly which prevents switching flashover |
| MXPA04003358A (es) * | 2001-10-12 | 2004-07-08 | Serenix Pharmaceuticals Llc | Antagonistas de vasopresina v1a de ?-lactamilo. |
| WO2006102283A2 (en) | 2005-03-22 | 2006-09-28 | Azevan Pharmaceuticals, Inc. | Beta-lactamylalkanoic acids for treating premenstrual disorders |
| EP1910346B1 (de) | 2005-07-19 | 2019-02-27 | Azevan Pharmaceuticals, Inc. | Beta-lactamyl-phenylalanin, -cystein und -serin als vasopressinantagonisten |
| JP5153631B2 (ja) * | 2006-07-28 | 2013-02-27 | 株式会社カネカ | 新規イミダゾリジノン誘導体とその製造方法及び光学活性アミノ酸の製造方法 |
| US20100016274A1 (en) * | 2006-09-14 | 2010-01-21 | Koppel Gary A | Beta-lactam cannabinoid receptor modulators |
| PL3351104T3 (pl) | 2010-07-01 | 2021-06-14 | Azevan Pharmaceuticals, Inc. | Związki do stosowania w leczeniu okresowych zaburzeń wybuchowych |
| SG10202001065SA (en) | 2014-03-28 | 2020-04-29 | Azevan Pharmaceuticals Inc | Compositions and methods for treating neurodegenerative diseases |
| MX2020002762A (es) | 2017-09-15 | 2020-09-17 | Azevan Pharmaceuticals Inc | Composiciones y métodos para tratar una lesión cerebral. |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3487071A (en) * | 1968-12-23 | 1969-12-30 | Bristol Myers Co | 3-blocked amino-delta**1,4-2-azetidinones |
| US3920696A (en) * | 1973-04-02 | 1975-11-18 | Lilly Co Eli | 2s-carboxyalkylthio-3r-imidoazetidin-4-ones and compounds useful in their preparation |
| US4166816A (en) * | 1975-05-05 | 1979-09-04 | Smithkline Corporation | Methods and intermediates for preparing cis-4-oxoazetidine intermediates |
| US4200572A (en) * | 1975-09-03 | 1980-04-29 | Smithkline Corporation | Substituted azetidinones |
| US4565654A (en) * | 1983-03-28 | 1986-01-21 | University Of Notre Dame Du Lac | N-Acyloxy monocyclic β-lactams |
| US4751299A (en) * | 1983-11-18 | 1988-06-14 | Takeda Chemical Industries, Ltd. | Optically active β-lactams and method of their production |
-
1986
- 1986-07-24 US US06/888,895 patent/US4772694A/en not_active Expired - Lifetime
-
1987
- 1987-07-21 CA CA000542653A patent/CA1308725C/en not_active Expired - Lifetime
- 1987-07-21 IL IL83269A patent/IL83269A/xx not_active IP Right Cessation
- 1987-07-21 KR KR1019870007911A patent/KR960000048B1/ko not_active Expired - Fee Related
- 1987-07-23 ES ES87306539T patent/ES2059384T3/es not_active Expired - Lifetime
- 1987-07-23 HU HU873397A patent/HU197741B/hu not_active IP Right Cessation
- 1987-07-23 EP EP87306539A patent/EP0254578B1/de not_active Expired - Lifetime
- 1987-07-23 AT AT87306539T patent/ATE94165T1/de not_active IP Right Cessation
- 1987-07-23 JP JP62186497A patent/JPH0757752B2/ja not_active Expired - Fee Related
- 1987-07-23 DE DE87306539T patent/DE3787333T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| KR960000048B1 (ko) | 1996-01-03 |
| ATE94165T1 (de) | 1993-09-15 |
| ES2059384T3 (es) | 1994-11-16 |
| EP0254578A1 (de) | 1988-01-27 |
| KR880001648A (ko) | 1988-04-25 |
| JPS6335571A (ja) | 1988-02-16 |
| JPH0757752B2 (ja) | 1995-06-21 |
| HUT45048A (en) | 1988-05-30 |
| US4772694A (en) | 1988-09-20 |
| HU197741B (en) | 1989-05-29 |
| DE3787333T2 (de) | 1994-02-03 |
| EP0254578B1 (de) | 1993-09-08 |
| DE3787333D1 (de) | 1993-10-14 |
| CA1308725C (en) | 1992-10-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| EXP | Patent expired |