IL83905A - Substituted phenylalkylamines, their preparation and psychostimulating pharmaceutical compositions comprising same - Google Patents

Substituted phenylalkylamines, their preparation and psychostimulating pharmaceutical compositions comprising same

Info

Publication number: IL83905A
Authority: IL; Israel
Prior art keywords: psychostimulating; preparation; same; pharmaceutical compositions; substituted
Prior art date: 1986-09-25

Application number

IL83905A

Other languages

English (en)

Original Assignee

Chinoin Gyogyszer Es Vegyeszet

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-09-25

Filing date

1987-09-15

Publication date

1993-07-08

1987-09-15 Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet

1993-07-08 Publication of IL83905A publication Critical patent/IL83905A/xx

Links

239000008194 pharmaceutical composition Substances 0.000 title 1
230000002582 psychostimulating effect Effects 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 2
125000000753 cycloalkyl group Chemical group 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000007812 deficiency Effects 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000003884 phenylalkyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
230000004936 stimulating effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants

Landscapes

Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Pain & Pain Management (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
External Artificial Organs (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

IL83905A 1986-09-25 1987-09-15 Substituted phenylalkylamines, their preparation and psychostimulating pharmaceutical compositions comprising same IL83905A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU864101A HU207280B (en)	1986-09-25	1986-09-25	Process for producing new phenyl-alkyl-amines and pharmaceutical compositions containing them

Publications (1)

Publication Number	Publication Date
IL83905A true IL83905A (en)	1993-07-08

Family

ID=10966901

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL83905A IL83905A (en)	1986-09-25	1987-09-15	Substituted phenylalkylamines, their preparation and psychostimulating pharmaceutical compositions comprising same

Country Status (21)

Country	Link
US (1)	US5075338A (cs)
EP (1)	EP0284621B1 (cs)
KR (1)	KR880701545A (cs)
AT (1)	ATE117204T1 (cs)
CS (1)	CS277418B6 (cs)
DD (1)	DD262226A5 (cs)
DE (1)	DE3751006T2 (cs)
DK (1)	DK282488A (cs)
ES (1)	ES2007411A6 (cs)
FI (1)	FI882474A7 (cs)
GE (1)	GEP19960656B (cs)
HU (1)	HU207280B (cs)
IL (1)	IL83905A (cs)
LT (2)	LT3531B (cs)
LV (2)	LV10860B (cs)
PL (1)	PL151642B1 (cs)
PT (1)	PT85799B (cs)
RU (1)	RU2007384C1 (cs)
SU (1)	SU1746882A3 (cs)
UA (3)	UA19171A (cs)
WO (1)	WO1988002254A1 (cs)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5430044A (en) *	1987-02-06	1995-07-04	Fisons Corporation	Arylalkyl-amines and -amides having anticonvulsant and neuroprotective properties
ES2083972T3 (es) *	1988-08-12	1996-05-01	Astra Ab	Arilalquil-aminas y -amidas con propiedades anticonvulsivas y neuroprotectoras.
HUT58270A (en) *	1989-06-02	1992-02-28	Wyeth John & Brother Ltd	Process for producing amine derivatives and pharmaceutical compositions containing them
US6011068A (en) *	1991-08-23	2000-01-04	Nps Pharmaceuticals, Inc.	Calcium receptor-active molecules
US6313146B1 (en)	1991-08-23	2001-11-06	Nps Pharmaceuticals, Inc.	Calcium receptor-active molecules
US6001884A (en) *	1991-08-23	1999-12-14	Nps Pharmaceuticals, Inc.	Calcium receptor-active molecules
HUT63579A (en) *	1991-12-20	1993-09-28	Chinoin Gyogyszer Es Vegyeszet	Process for producing double-phase pharmaceutical compositions suitable for treating diseases occurring during neurodegenerative processes
EP1275635A1 (en)	1994-10-21	2003-01-15	Nps Pharmaceuticals, Inc.	Calcium receptor-active compounds
US6033682A (en)	1995-01-13	2000-03-07	Somerset Pharmaceuticals, Inc.	S(+) desmethylselegiline and its use in therapeutic methods and pharmaceutical compositions
US6348208B1 (en)	1995-01-13	2002-02-19	Somerset Pharmaceuticals, Inc.	Methods and pharmaceutical compositions employing desmethylselegiline
US6319954B1 (en)	1995-01-13	2001-11-20	Somerset Pharmaceuticals, Inc.	S-(+)-desmethylselegiline and its use in the therapeutic methods and pharmaceutical compositions
US6299901B1 (en)	1995-01-13	2001-10-09	Somerset Pharmaceuticals, Inc.	Methods and pharmaceutical compositions employing desmethylselegiline
CA2223588C (en) *	1995-06-07	2004-01-06	Noven Pharmaceuticals, Inc.	Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures
US6316022B1 (en)	1995-06-07	2001-11-13	Noven Pharmaceuticals, Inc.	Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures
JP4117506B2 (ja) *	1996-05-01	2008-07-16	エヌピーエスファーマシューティカルズインコーポレイテッド	無機イオン活性化合物
EP0957080B1 (en) *	1997-08-07	2006-06-21	Fujimoto Brothers Co., Ltd.	Novel ethylamine derivatives
JP4499208B2 (ja)	1998-10-29	2010-07-07	株式会社フジモト・コーポレーション	新規な光学活性アミノペンタン誘導体
US20030119884A1 (en) *	2000-11-01	2003-06-26	Epstein Mel H.	Methods and compositions for regulating memory consolidation
WO2005000203A2 (en)	2001-10-31	2005-01-06	Sention, Inc.	Methods for treating cognitive impairment and improving cognition
US20030232890A1 (en) *	2000-11-01	2003-12-18	Sention, Inc.	Methods for treating an impairment in memory consolidation
TWI291871B (en) *	2000-11-01	2008-01-01	Cognition Pharmaceuticals Llc	Pharmaceutical compositions and use of amphetamine compounds for improving memory and learning
US20050059743A1 (en) *	2000-11-01	2005-03-17	Sention, Inc.	Methods for treating mild cognitive impairment and alzheimer's disease
US20070117869A1 (en) *	2000-11-01	2007-05-24	Cognition Pharmaceuticals Llc	Methods for treating coginitive impairment and improving cognition
US7619005B2 (en) *	2000-11-01	2009-11-17	Cognition Pharmaceuticals Llc	Methods for treating cognitive impairment in humans with Multiple Sclerosis
WO2002087423A2 (en) *	2001-05-02	2002-11-07	Blanchette Rockefeller Neurosciences Institute	Carbonic anhydrase activators for enhancing learning and memory
EP1935414A3 (en) *	2001-05-02	2010-08-18	Blanchette Rockefeller Neurosciences Institute	Carbonic anhydrase activators for enhancig learning and memory
TW201207390A (en)	2004-05-18	2012-02-16	Brni Neurosciences Inst	Method for screening agent for antidepressant activity
CA2758774C (en)	2009-04-15	2015-02-03	Research Triangle Institute	Monoamine reuptake inhibitors
WO2016088111A1 (en)	2014-12-05	2016-06-09	Semmelweis University	Arylalkylamine compounds for use in the prevention or treatment of cancer

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US485926A (en)		1892-11-08		Field
DE767263C (de) *	1937-10-03	1952-03-31	Theodor H Temmler	Verfahren zur Herstellung von ª-Aralkylaminen
DE893341C (de) *	1950-08-23	1953-10-15	Troponwerke Dinklage & Co	Verfahren zur Herstellung von N-Aralkyl-ª-phenyl-isopropylaminen
US2797242A (en) *	1953-08-11	1957-06-25	Parke Davis & Co	Substituted alpha-benzylphenethylamines and methods for producing the same
DE227447C (cs)	1955-03-23	1910-10-21
DE1210873B (de) *	1959-03-18	1966-02-17	Hoffmann La Roche	Verfahren zur Herstellung von Halogenalkylaminen
US3044932A (en) *	1960-02-24	1962-07-17	Upjohn Co	Appetite suppressant drugs
DE1133395B (de) *	1960-11-12	1962-07-19	Hoechst Ag	Verfahren zur Herstellung von herz- und kreislaufwirksamen Phenylalkylaminen
DE1227447B (de) *	1962-03-30	1966-10-27	Chinoin Gyogyszer Es Vegyeszet	Verfahren zur Herstellung von Phenylisopropylaminen
GB1031425A (en) *	1962-03-30	1966-06-02	Chinoin Gyogyszer Es Vegyeszet	New aralkylamines and their preparation
FR1478311A (fr) *	1963-10-18	1967-04-28	Koninklijke Pharma Fab Nv	Procédé de préparation d'aminoalcanes et produits en résultant
GB1218135A (en) *	1967-07-28	1971-01-06	Abbott Lab	Substituted phenethylamine derivatives
DE2143204C3 (de) *	1971-08-28	1979-09-27	Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt	N-Fluoralkyl-phenylisopropylamin-Derivate und deren Salze, Verfahren zu deren Herstellung und Arzneimittel auf deren Basis
US4025624A (en) *	1975-11-18	1977-05-24	A. H. Robins Company, Incorporated	Phenylalkylamines and phenylalkylureas in combinations to suppress gastric bleeding in aspirin therapy
US4404222A (en) *	1980-08-25	1983-09-13	American Cyanamid Company	Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and improving the efficiency of feed utilization thereby
DD145599A1 (de) *	1979-08-23	1980-12-24	Roswitha Toepfer	Mittel zur regulierung des pflanzenwachstums

1986
- 1986-09-25 HU HU864101A patent/HU207280B/hu not_active IP Right Cessation
1987
- 1987-09-15 IL IL83905A patent/IL83905A/xx not_active IP Right Cessation
- 1987-09-21 DD DD87307094A patent/DD262226A5/de not_active IP Right Cessation
- 1987-09-23 ES ES8702717A patent/ES2007411A6/es not_active Expired
- 1987-09-25 PL PL1987267913A patent/PL151642B1/pl unknown
- 1987-09-25 DE DE3751006T patent/DE3751006T2/de not_active Expired - Fee Related
- 1987-09-25 EP EP87906316A patent/EP0284621B1/en not_active Expired - Lifetime
- 1987-09-25 PT PT85799A patent/PT85799B/pt not_active IP Right Cessation
- 1987-09-25 CS CS876898A patent/CS277418B6/cs unknown
- 1987-09-25 WO PCT/HU1987/000040 patent/WO1988002254A1/en not_active Ceased
- 1987-09-25 UA UA4742460A patent/UA19171A/uk unknown
- 1987-09-25 UA UA4355858A patent/UA11100A/uk unknown
- 1987-09-25 AT AT87906316T patent/ATE117204T1/de not_active IP Right Cessation
1988
- 1988-05-24 DK DK282488A patent/DK282488A/da not_active Application Discontinuation
- 1988-05-24 KR KR1019880700574A patent/KR880701545A/ko not_active Ceased
- 1988-05-24 SU SU884355858A patent/SU1746882A3/ru active
- 1988-05-25 FI FI882474A patent/FI882474A7/fi not_active IP Right Cessation
1989
- 1989-10-11 US US07/420,058 patent/US5075338A/en not_active Expired - Fee Related
- 1989-11-23 RU SU894742460A patent/RU2007384C1/ru active
1990
- 1990-09-10 UA UA4830945A patent/UA19808A/uk unknown
1993
- 1993-06-22 LV LVP-93-650A patent/LV10860B/lv unknown
- 1993-06-22 LV LVP-93-651A patent/LV10709B/lv unknown
- 1993-08-12 GE GEAP19931393A patent/GEP19960656B/en unknown
- 1993-08-19 LT LTIP879A patent/LT3531B/lt not_active IP Right Cessation
- 1993-08-19 LT LTIP878A patent/LT3530B/lt not_active IP Right Cessation

Also Published As

Publication number	Publication date
ES2007411A6 (es)	1989-06-16
FI882474A0 (fi)	1988-05-25
LTIP879A (en)	1995-03-27
DK282488D0 (da)	1988-05-24
LV10860A (lv)	1995-10-20
LV10709A (lv)	1995-06-20
LT3531B (en)	1995-11-27
EP0284621B1 (en)	1995-01-18
FI882474A7 (fi)	1988-05-25
RU2007384C1 (ru)	1994-02-15
HU207280B (en)	1993-03-29
PT85799A (en)	1987-10-01
DD262226A5 (de)	1988-11-23
DE3751006D1 (de)	1995-03-02
WO1988002254A1 (en)	1988-04-07
UA19171A (uk)	1997-12-25
GEP19960656B (en)	1996-12-24
LV10709B (en)	1995-12-20
PL151642B1 (en)	1990-09-28
LT3530B (en)	1995-11-27
PT85799B (pt)	1990-08-31
UA11100A (uk)	1996-12-25
EP0284621A1 (en)	1988-10-05
DE3751006T2 (de)	1995-05-24
KR880701545A (ko)	1988-11-03
CS277418B6 (en)	1993-03-17
SU1746882A3 (ru)	1992-07-07
US5075338A (en)	1991-12-24
PL267913A1 (en)	1989-03-06
UA19808A (uk)	1997-12-25
DK282488A (da)	1988-05-24
LV10860B (en)	1996-04-20
CS689887A3 (en)	1992-08-12
HUT45962A (en)	1988-09-28
LTIP878A (en)	1995-03-27
ATE117204T1 (de)	1995-02-15

Legal Events

Date	Code	Title	Description
1998-09-24	RH	Patent void

Publication	Publication Date	Title
CS689887A3 (en)	1992-08-12	Novel psychostimulating substances of the phenylalkylamine derivativestype, process of their preparation and pharmaceuticals comprising them
KR890011592A (ko)	1989-08-21	기관내 허혈병의 치료용 조성물
GR860900B (en)	1986-08-04	Amino-propanol derivatives method for their preparation their use and medicaments containing them
ES539123A0 (es)	1986-03-16	Un compuesto de 3-indolcarboxamida
FR2549049B1 (fr)	1986-06-20	Nouvelles amidines, leur procede de preparation et leur application therapeutique
IL79910A (en)	1990-02-09	5,7-dihydro-6-(thi)oxopyrrolo(2,3-f)benzimidazole,-benzothiazole and-benzoxazoles,6-imines thereof,their preparation and pharmaceutical compositions containing them
DK0514357T3 (da)	1996-02-26	Anvendelse af estere af acyl-L-carnitiner med gamma-hydroxysmørsyre til fremstilling af farmaceutiske præparater til behandling af hepatopatier
GB8706662D0 (en)	1987-04-23	Anti-arrhythmia agents
ATE70182T1 (de)	1991-12-15	Therapeutische mittel zur behandlung von magengeschwueren.
ES8507469A1 (es)	1985-09-01	Procedimiento de obtencion de agentes de beta-bloqueantes conteniendo grupos ester con propiedades oftalmologicas
ES8300095A1 (es)	1982-10-01	"un procedimiento para preparar derivados de halofenil-piridil-alilamina".
CA2038025A1 (en)	1991-09-15	Optically active alkylenedioxybenzene derivatives and their use in therapy
IL73567A0 (en)	1985-02-28	Glycosyl-amide,-urea,-carbamate and-thiocarbamate derivatives,their preparation and pharmaceutical compositions containing them
ZA903111B (en)	1991-12-24	2-hydroxy-3-phenoxypropylamino compounds and pharmaceutical compositions containing them
KR900000383A (ko)	1990-01-30	신규 화합물
SE8701887D0 (sv)	1987-05-07	Nouveaux derives de l'acide 4-phenyl 4-oxo 2-butenoique, leur procede de preparation, leur application comme medicaments et les compositions les renfermant
KR950704322A (ko)	1995-11-17	스피로푸라논 유도체 및 그의 신경변성 질환 치료 용도(Spirofuranone Derivatives and Their Use in the Treatment of Neurodegenerative Disorders)
EP0447812A3 (en)	1992-07-08	Use of a dihydropyridine to improve the inner ear blood circulation
DK0674645T3 (da)	1997-09-01	Cephemforbindelser med antimikrobiel virkning
FR2481697B1 (cs)	1984-02-17
IT1248525B (it)	1995-01-19	Derivati dell'eseridina utili per il trattamento delle malattie associate a disordini colinergici, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.