IL83912A - Protein having anticoagulant and antimetastatic properties - Google Patents

Protein having anticoagulant and antimetastatic properties

Info

Publication number
IL83912A
IL83912A IL83912A IL8391287A IL83912A IL 83912 A IL83912 A IL 83912A IL 83912 A IL83912 A IL 83912A IL 8391287 A IL8391287 A IL 8391287A IL 83912 A IL83912 A IL 83912A
Authority
IL
Israel
Prior art keywords
anticoagulant
protein
antimetastatic properties
antimetastatic
properties
Prior art date
Application number
IL83912A
Other languages
English (en)
Other versions
IL83912A0 (en
Original Assignee
Pennsylvania Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pennsylvania Hospital filed Critical Pennsylvania Hospital
Publication of IL83912A0 publication Critical patent/IL83912A0/xx
Publication of IL83912A publication Critical patent/IL83912A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/14—Angiotensins: Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL83912A 1986-09-18 1987-09-15 Protein having anticoagulant and antimetastatic properties IL83912A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90858186A 1986-09-18 1986-09-18
US8843287A 1987-08-26 1987-08-26

Publications (2)

Publication Number Publication Date
IL83912A0 IL83912A0 (en) 1988-02-29
IL83912A true IL83912A (en) 1993-05-13

Family

ID=26778655

Family Applications (1)

Application Number Title Priority Date Filing Date
IL83912A IL83912A (en) 1986-09-18 1987-09-15 Protein having anticoagulant and antimetastatic properties

Country Status (9)

Country Link
EP (1) EP0263608A3 (de)
KR (1) KR880003975A (de)
AU (1) AU615635B2 (de)
DK (1) DK489187A (de)
FI (1) FI874055L (de)
IL (1) IL83912A (de)
NO (1) NO170430C (de)
NZ (1) NZ221835A (de)
PT (1) PT85746B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3819078A1 (de) * 1988-06-04 1989-12-07 Hoechst Ag Amblyommin, ein neuer wirkstoff fuer die antikoagulationstherapie
US5268296A (en) * 1988-06-11 1993-12-07 Ciba-Geigy Corporation DNA vector and recombinant host cell for production of hirullin P6 and P18
DE58907266T2 (de) * 1988-06-11 1994-09-29 Ciba Geigy Ag Polypeptide mit einer die Koagulierung hemmenden Wirkung.
US4832849A (en) * 1988-06-16 1989-05-23 Merrell Dow Pharmaceuticals Inc. Extraction and purification of an anticoagulant principle from the south american leech, haementeria ghilianii
KR0185973B1 (ko) * 1989-06-20 1999-05-01 게리 디. 스트리트 남미의 거머리인 헤멘테리아 길리아니로부터의 항전이 물질 길란텐
US5190918A (en) * 1990-02-22 1993-03-02 W. R. Grace & Co.-Conn. Peptide fragments and analogs of thrombospondin and methods of use
US5200397A (en) * 1990-02-22 1993-04-06 W. R. Grace & Co.-Conn. Use of peptide analogs of thrombospondin for the inhibition of angiogenic activity
US5648461A (en) * 1990-02-22 1997-07-15 W.R. Grace & Co.-Conn Synthetic analogs of thrombospondin and therapeutic use thereof
US6239110B1 (en) 1990-02-22 2001-05-29 W.R. Grace & Co. -Conn. Synthetic analogs of thrombospondin and therapeutic use thereof
CA2047527A1 (en) * 1990-07-24 1992-01-25 Christopher Dunwiddie Method for administering a therapeutic anticoagulant
CA2052486A1 (en) * 1990-10-09 1992-04-10 Thomas M. Connolly Protein for inhibiting collagen-stimulated platelet aggregation
ATE213155T1 (de) * 1993-04-09 2002-02-15 Bio Technology General Corp Herstellung eines rekombinanten inhibitors des faktors xa des blutegels hirudo medicinalis
US5824641A (en) 1993-04-09 1998-10-20 Bio-Technology General Corp Method of treating of preventing influenza
US6339062B1 (en) 1998-11-23 2002-01-15 Inkine Pharmaceutical Company, Inc. Retroinverso polypeptides that mimic or inhibit thrombospondin activity
GB9930659D0 (en) * 1999-12-24 2000-02-16 Bio Discovery Ltd Inhibitors of complement activation
EP1931733A4 (de) 2005-09-28 2009-11-25 Biovascular Inc Verfahren und zusammensetzungen zum blockieren von thrombozyten- und zelladhäsion, zellmigration und entzündung
CN109620847B (zh) * 2018-12-11 2022-07-26 山东沃华医药科技股份有限公司 一种脑血疏口服液中的水蛭抗凝成分的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4588587A (en) * 1983-03-01 1986-05-13 Pennsylvania Hospital Method of treatment to inhibit metastasis

Also Published As

Publication number Publication date
IL83912A0 (en) 1988-02-29
EP0263608A2 (de) 1988-04-13
PT85746B (pt) 1990-07-31
AU615635B2 (en) 1991-10-10
EP0263608A3 (de) 1989-06-14
PT85746A (en) 1987-10-01
NO170430B (no) 1992-07-06
DK489187A (da) 1988-03-19
NO873859D0 (no) 1987-09-15
AU7862687A (en) 1988-03-24
KR880003975A (ko) 1988-05-31
FI874055A0 (fi) 1987-09-17
FI874055A7 (fi) 1988-03-19
DK489187D0 (da) 1987-09-17
NO873859L (no) 1988-03-21
NO170430C (no) 1992-10-14
FI874055L (fi) 1988-03-19
NZ221835A (en) 1992-03-26

Similar Documents

Publication Publication Date Title
GB8604983D0 (en) Protein preservation
DE3275923D1 (en) Conjugates of anticoagulant and protein
IL76441A (en) Blood coagulation inhibiting proteins and their preparation
IL83912A (en) Protein having anticoagulant and antimetastatic properties
AU586559B2 (en) Combination stretcher and stairchair
GB8724412D0 (en) Protein
EP0279459A3 (en) Anticoagulant polypeptide
EP0255801A3 (en) Anilinotriazines and their use
GB2190918B (en) Polyanhydride-siloxanes and polyimide-siloxanes obtained therefrom
DE3760806D1 (en) Monohalogenotrifluorooxetane and its preparation
EP0351826A3 (en) Anticoagulant polypeptide
IE872516L (en) Protein having anticoagulant and antimetastatic properties
EP0196568A3 (en) Blood anticoagulant and process for preparing the same
GB8725462D0 (en) Protein
GB2194235B (en) Dichlorotrifluoromethyltoluenes and preparation thereof
GB8816095D0 (en) Protein
GB8725463D0 (en) Protein
PT86162A (en) Recombinant protein expression
EP0233740A3 (en) Aerocavin and aerocyanidin - antibiotics
GB2191482B (en) Substituted pyrimidoindoles and diazepinoindoles
IE862835L (en) Protein modification
GB8609162D0 (en) Protein
GB8602996D0 (en) Protein
ZA882192B (en) Vascular anticoagulant proteins
KR890009433Y1 (en) Chopsticks