IL88453A - Process for producing thio- tepa: n,n), n*-triethylene thiophosphoramide - Google Patents

Process for producing thio- tepa: n,n), n*-triethylene thiophosphoramide

Info

Publication number: IL88453A
Authority: IL; Israel
Prior art keywords: tepa; triethylene thiophosphoramide; producing thio; thio; producing
Prior art date: 1988-01-21

Application number

IL88453A

Other languages

English (en)

Other versions

IL88453A0 (en

Original Assignee

American Cyanamid Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-01-21

Filing date

1988-11-22

Publication date

1993-01-14

1988-11-22 Application filed by American Cyanamid Co filed Critical American Cyanamid Co

1989-06-30 Publication of IL88453A0 publication Critical patent/IL88453A0/xx

1993-01-14 Publication of IL88453A publication Critical patent/IL88453A/xx

Links

FOCVUCIESVLUNU-UHFFFAOYSA-N Thiotepa Chemical compound C1CN1P(N1CC1)(=S)N1CC1 FOCVUCIESVLUNU-UHFFFAOYSA-N 0.000 title 1
229960001196 thiotepa Drugs 0.000 title 1
NOWKCMXCCJGMRR-UHFFFAOYSA-N Aziridine Chemical compound C1CN1 NOWKCMXCCJGMRR-UHFFFAOYSA-N 0.000 abstract 1
238000011065 in-situ storage Methods 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/564—Three-membered rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Biochemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cephalosporin Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

IL88453A 1988-01-21 1988-11-22 Process for producing thio- tepa: n,n), n*-triethylene thiophosphoramide IL88453A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/146,511 US4918199A (en)	1988-01-21	1988-01-21	Process for producing thiotepa

Publications (2)

Publication Number	Publication Date
IL88453A0 IL88453A0 (en)	1989-06-30
IL88453A true IL88453A (en)	1993-01-14

Family

ID=22517714

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL88453A IL88453A (en)	1988-01-21	1988-11-22	Process for producing thio- tepa: n,n), n*-triethylene thiophosphoramide

Country Status (10)

Country	Link
US (1)	US4918199A (de)
EP (1)	EP0324920B1 (de)
JP (1)	JPH021496A (de)
KR (1)	KR0135608B1 (de)
AT (1)	ATE111474T1 (de)
CA (1)	CA1282073C (de)
DE (1)	DE3851523T2 (de)
ES (1)	ES2059474T3 (de)
FI (1)	FI90776C (de)
IL (1)	IL88453A (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5561121A (en) *	1993-11-09	1996-10-01	American Cyanamid Company	Stable lyophilized thiotepa composition
WO2001061340A1 (en) *	2000-02-18	2001-08-23	Matsushita Electric Industrial Co., Ltd.	Measuring system
CN108484669B (zh) *	2018-06-01	2020-07-07	黑龙江福和制药集团股份有限公司	塞替派的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2212146A (en) *	1939-03-10	1940-08-20	Du Pont	Preparation of alpha-alkylenimines, e. g., ethylenimine
US2670347A (en) *	1952-01-08	1954-02-23	American Cyanamid Co	Thiophosphoric acid derivatives and method of preparing the same

1988
- 1988-01-21 US US07/146,511 patent/US4918199A/en not_active Expired - Lifetime
- 1988-11-22 IL IL88453A patent/IL88453A/xx not_active IP Right Cessation
- 1988-11-23 AT AT88119469T patent/ATE111474T1/de not_active IP Right Cessation
- 1988-11-23 EP EP88119469A patent/EP0324920B1/de not_active Expired - Lifetime
- 1988-11-23 ES ES88119469T patent/ES2059474T3/es not_active Expired - Lifetime
- 1988-11-23 DE DE3851523T patent/DE3851523T2/de not_active Expired - Fee Related
- 1988-12-26 KR KR1019880017532A patent/KR0135608B1/ko not_active Expired - Fee Related
1989
- 1989-01-18 JP JP1007904A patent/JPH021496A/ja active Granted
- 1989-01-19 CA CA000588625A patent/CA1282073C/en not_active Expired - Fee Related
- 1989-01-20 FI FI890309A patent/FI90776C/fi not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA1282073C (en)	1991-03-26
KR890011898A (ko)	1989-08-23
ATE111474T1 (de)	1994-09-15
FI890309L (fi)	1989-07-22
EP0324920B1 (de)	1994-09-14
FI890309A0 (fi)	1989-01-20
JPH021496A (ja)	1990-01-05
DE3851523T2 (de)	1995-03-16
FI90776C (fi)	1994-03-25
EP0324920A2 (de)	1989-07-26
IL88453A0 (en)	1989-06-30
ES2059474T3 (es)	1994-11-16
EP0324920A3 (en)	1990-10-31
US4918199A (en)	1990-04-17
FI90776B (fi)	1993-12-15
KR0135608B1 (ko)	1998-04-23
JPH0579075B2 (de)	1993-11-01
DE3851523D1 (de)	1994-10-20

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Legal Events

Date	Code	Title	Description
2003-01-12	KB	Patent renewed
2007-07-24	MM9K	Patent not in force due to non-payment of renewal fees