IL90996A - S-adenosyl-methionine decarboxylase inhibitors, method for their preparation and pharmaceutical compositions containing them - Google Patents

S-adenosyl-methionine decarboxylase inhibitors, method for their preparation and pharmaceutical compositions containing them

Info

Publication number
IL90996A
IL90996A IL9099689A IL9099689A IL90996A IL 90996 A IL90996 A IL 90996A IL 9099689 A IL9099689 A IL 9099689A IL 9099689 A IL9099689 A IL 9099689A IL 90996 A IL90996 A IL 90996A
Authority
IL
Israel
Prior art keywords
compound
deoxy
mmol
amino
cis
Prior art date
Application number
IL9099689A
Other languages
English (en)
Other versions
IL90996A0 (en
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP88401896A external-priority patent/EP0351475A1/en
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of IL90996A0 publication Critical patent/IL90996A0/xx
Publication of IL90996A publication Critical patent/IL90996A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/167—Purine radicals with ribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
IL9099689A 1988-07-21 1989-07-17 S-adenosyl-methionine decarboxylase inhibitors, method for their preparation and pharmaceutical compositions containing them IL90996A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP88401896A EP0351475A1 (en) 1988-07-21 1988-07-21 S-Adenosylmethionine decarboxylase inhibitors
EP89401845A EP0358536B1 (en) 1988-07-21 1989-06-28 Novel S-adenosyl methionine decarboxylase inhibitors

Publications (2)

Publication Number Publication Date
IL90996A0 IL90996A0 (en) 1990-02-09
IL90996A true IL90996A (en) 1994-11-28

Family

ID=26117870

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9099689A IL90996A (en) 1988-07-21 1989-07-17 S-adenosyl-methionine decarboxylase inhibitors, method for their preparation and pharmaceutical compositions containing them

Country Status (12)

Country Link
EP (1) EP0358536B1 (da)
JP (1) JP2789228B2 (da)
KR (1) KR0150633B1 (da)
CN (1) CN1026115C (da)
CA (1) CA1335201C (da)
DK (1) DK171027B1 (da)
FI (1) FI94644C (da)
IE (1) IE81169B1 (da)
IL (1) IL90996A (da)
NO (1) NO171982C (da)
NZ (1) NZ229955A (da)
PT (1) PT91235B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA916464B (en) * 1990-08-22 1992-05-27 Merrell Dow Pharma 5'-amine substituted adenosine analogs as immunosuppressants
US5308837A (en) * 1990-08-22 1994-05-03 Merrell Dow Pharmaceuticals Inc. 5'-amine substituted adenosine analogs as immunosuppressants
US6020139A (en) * 1995-04-25 2000-02-01 Oridigm Corporation S-adenosyl methionine regulation of metabolic pathways and its use in diagnosis and therapy
EP1221615A2 (en) 1995-04-25 2002-07-10 Oridigm Corporation S-adenosyl methionine regulation of metabolic pathways and its use in diagnosis and therapy
KR100456970B1 (ko) * 2001-12-31 2004-11-10 주식회사 디피아이 우레탄 변성 폴리에스테르 수지 조성물, 이의 제조 방법및 이를 포함하는 도료 조성물
KR100496049B1 (ko) * 2001-12-31 2005-06-17 주식회사 디피아이 열경화성 우레탄 변성 폴리에스테르 수지 조성물
EP1408028A1 (en) * 2002-10-09 2004-04-14 Institut National De La Sante Et De La Recherche Medicale (Inserm) S-adenosyl methionine decarboxylase inhibition for the treatment of a herpes simplex virus infection
JP2010535202A (ja) * 2007-08-02 2010-11-18 サザン リサーチ インスティテュート ５’−置換アデノシン、その製造、及び、ｓ−アデノシルメチオニン脱炭酸酵素の阻害剤としての使用

Also Published As

Publication number Publication date
PT91235A (pt) 1990-02-08
KR910002891A (ko) 1991-02-26
IE81169B1 (en) 2000-05-31
JP2789228B2 (ja) 1998-08-20
AU3886689A (en) 1990-02-01
NZ229955A (en) 1991-03-26
PT91235B (pt) 1995-03-01
JPH02191296A (ja) 1990-07-27
FI893507A0 (fi) 1989-07-20
IL90996A0 (en) 1990-02-09
EP0358536A3 (en) 1991-04-03
CN1039422A (zh) 1990-02-07
CA1335201C (en) 1995-04-11
NO892977D0 (no) 1989-07-20
IE892364L (en) 1990-01-21
FI893507A7 (fi) 1990-01-22
EP0358536A2 (en) 1990-03-14
NO171982C (no) 1993-05-26
DK360189A (da) 1990-01-22
EP0358536B1 (en) 1996-05-08
CN1026115C (zh) 1994-10-05
KR0150633B1 (ko) 1998-08-17
DK171027B1 (da) 1996-04-22
DK360189D0 (da) 1989-07-20
FI94644B (fi) 1995-06-30
NO171982B (no) 1993-02-15
FI94644C (fi) 1995-10-10
AU610740B2 (en) 1991-05-23
NO892977L (no) 1990-01-22

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Legal Events

Date Code Title Description
KB Patent renewed
RH1 Patent not in force
HC Change of name of proprietor(s)

Owner name: AVENTIS INC.

Free format text: FORMER NAME:MERRELL PHARMACEUTICALS INC.