NO171982C - Analogifremgangsmaate for fremstilling av nye terapeutisk aktive s-adenosylmethionindecarboxylase-inhibitorer, og mellomprodukter derfor - Google Patents

Analogifremgangsmaate for fremstilling av nye terapeutisk aktive s-adenosylmethionindecarboxylase-inhibitorer, og mellomprodukter derfor

Info

Publication number
NO171982C
NO171982C NO892977A NO892977A NO171982C NO 171982 C NO171982 C NO 171982C NO 892977 A NO892977 A NO 892977A NO 892977 A NO892977 A NO 892977A NO 171982 C NO171982 C NO 171982C
Authority
NO
Norway
Prior art keywords
indecarboxylase
adenosylmethion
intermediates
inhibitors
preparation
Prior art date
Application number
NO892977A
Other languages
English (en)
Norwegian (no)
Other versions
NO892977D0 (no
NO171982B (no
NO892977L (no
Inventor
Patrick Casara
Charles Danzin
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP88401896A external-priority patent/EP0351475A1/en
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of NO892977D0 publication Critical patent/NO892977D0/no
Publication of NO892977L publication Critical patent/NO892977L/no
Publication of NO171982B publication Critical patent/NO171982B/no
Publication of NO171982C publication Critical patent/NO171982C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/167—Purine radicals with ribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
NO892977A 1988-07-21 1989-07-20 Analogifremgangsmaate for fremstilling av nye terapeutisk aktive s-adenosylmethionindecarboxylase-inhibitorer, og mellomprodukter derfor NO171982C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP88401896A EP0351475A1 (en) 1988-07-21 1988-07-21 S-Adenosylmethionine decarboxylase inhibitors
EP89401845A EP0358536B1 (en) 1988-07-21 1989-06-28 Novel S-adenosyl methionine decarboxylase inhibitors

Publications (4)

Publication Number Publication Date
NO892977D0 NO892977D0 (no) 1989-07-20
NO892977L NO892977L (no) 1990-01-22
NO171982B NO171982B (no) 1993-02-15
NO171982C true NO171982C (no) 1993-05-26

Family

ID=26117870

Family Applications (1)

Application Number Title Priority Date Filing Date
NO892977A NO171982C (no) 1988-07-21 1989-07-20 Analogifremgangsmaate for fremstilling av nye terapeutisk aktive s-adenosylmethionindecarboxylase-inhibitorer, og mellomprodukter derfor

Country Status (12)

Country Link
EP (1) EP0358536B1 (da)
JP (1) JP2789228B2 (da)
KR (1) KR0150633B1 (da)
CN (1) CN1026115C (da)
CA (1) CA1335201C (da)
DK (1) DK171027B1 (da)
FI (1) FI94644C (da)
IE (1) IE81169B1 (da)
IL (1) IL90996A (da)
NO (1) NO171982C (da)
NZ (1) NZ229955A (da)
PT (1) PT91235B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5308837A (en) * 1990-08-22 1994-05-03 Merrell Dow Pharmaceuticals Inc. 5'-amine substituted adenosine analogs as immunosuppressants
ZA916464B (en) * 1990-08-22 1992-05-27 Merrell Dow Pharma 5'-amine substituted adenosine analogs as immunosuppressants
US6020139A (en) * 1995-04-25 2000-02-01 Oridigm Corporation S-adenosyl methionine regulation of metabolic pathways and its use in diagnosis and therapy
JPH11506426A (ja) 1995-04-25 1999-06-08 オリディグム コーポレイション 代謝経路のｓ−アデノシルメチオニン調節ならびに診断および治療におけるその使用
KR100496049B1 (ko) * 2001-12-31 2005-06-17 주식회사 디피아이 열경화성 우레탄 변성 폴리에스테르 수지 조성물
KR100456970B1 (ko) * 2001-12-31 2004-11-10 주식회사 디피아이 우레탄 변성 폴리에스테르 수지 조성물, 이의 제조 방법및 이를 포함하는 도료 조성물
EP1408028A1 (en) * 2002-10-09 2004-04-14 Institut National De La Sante Et De La Recherche Medicale (Inserm) S-adenosyl methionine decarboxylase inhibition for the treatment of a herpes simplex virus infection
EP2574616A3 (en) * 2007-08-02 2013-09-04 Southern Research Institute 5'-substituted adenosynes, preparation thereof and use as inhibitors of s-adenosylmethionine decarboxylase.

Also Published As

Publication number Publication date
FI94644C (fi) 1995-10-10
KR910002891A (ko) 1991-02-26
EP0358536B1 (en) 1996-05-08
EP0358536A3 (en) 1991-04-03
NO892977D0 (no) 1989-07-20
IL90996A0 (en) 1990-02-09
AU610740B2 (en) 1991-05-23
IL90996A (en) 1994-11-28
NZ229955A (en) 1991-03-26
PT91235B (pt) 1995-03-01
IE892364L (en) 1990-01-21
DK360189D0 (da) 1989-07-20
FI893507A7 (fi) 1990-01-22
JP2789228B2 (ja) 1998-08-20
PT91235A (pt) 1990-02-08
CN1039422A (zh) 1990-02-07
DK360189A (da) 1990-01-22
CN1026115C (zh) 1994-10-05
NO171982B (no) 1993-02-15
AU3886689A (en) 1990-02-01
CA1335201C (en) 1995-04-11
FI893507A0 (fi) 1989-07-20
KR0150633B1 (ko) 1998-08-17
FI94644B (fi) 1995-06-30
NO892977L (no) 1990-01-22
EP0358536A2 (en) 1990-03-14
DK171027B1 (da) 1996-04-22
IE81169B1 (en) 2000-05-31
JPH02191296A (ja) 1990-07-27

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