IL91369A - LFA-1alpha subunit and derivatives thereof free of natural contaminants, and pharmaceutical compositions containing it - Google Patents

LFA-1alpha subunit and derivatives thereof free of natural contaminants, and pharmaceutical compositions containing it

Info

Publication number
IL91369A
IL91369A IL9136989A IL9136989A IL91369A IL 91369 A IL91369 A IL 91369A IL 9136989 A IL9136989 A IL 9136989A IL 9136989 A IL9136989 A IL 9136989A IL 91369 A IL91369 A IL 91369A
Authority
IL
Israel
Prior art keywords
lfa
subunit
alpha
molecule
functional derivative
Prior art date
Application number
IL9136989A
Other languages
English (en)
Other versions
IL91369A0 (en
Original Assignee
Dana Farber Cancer Inst Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dana Farber Cancer Inst Inc filed Critical Dana Farber Cancer Inst Inc
Publication of IL91369A0 publication Critical patent/IL91369A0/xx
Publication of IL91369A publication Critical patent/IL91369A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70546—Integrin superfamily
    • C07K14/70553—Integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
IL9136989A 1988-08-23 1989-08-21 LFA-1alpha subunit and derivatives thereof free of natural contaminants, and pharmaceutical compositions containing it IL91369A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23522788A 1988-08-23 1988-08-23
US32101789A 1989-03-09 1989-03-09

Publications (2)

Publication Number Publication Date
IL91369A0 IL91369A0 (en) 1990-04-29
IL91369A true IL91369A (en) 1994-08-26

Family

ID=26928699

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9136989A IL91369A (en) 1988-08-23 1989-08-21 LFA-1alpha subunit and derivatives thereof free of natural contaminants, and pharmaceutical compositions containing it

Country Status (14)

Country Link
EP (1) EP0362526B1 (de)
JP (1) JPH02306999A (de)
KR (1) KR900002796A (de)
AT (1) ATE123810T1 (de)
AU (1) AU634974B2 (de)
DE (1) DE68923048T2 (de)
DK (1) DK412589A (de)
ES (1) ES2075016T3 (de)
FI (1) FI893916L (de)
GR (1) GR3017303T3 (de)
HU (1) HUT53673A (de)
IL (1) IL91369A (de)
NO (1) NO893366L (de)
PT (1) PT91503B (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988006592A1 (en) * 1987-02-26 1988-09-07 Dana-Farber Cancer Institute, Inc. Cloning of lfa-1
US5395929A (en) * 1987-12-15 1995-03-07 Dana Farber Cancer Institute Isolated nucleic acid encoding the alpha subunit of the human leukocyte adhesion receptor
US6514936B1 (en) 1988-09-01 2003-02-04 Bayer Corporation Antiviral methods using human rhinovirus receptor (ICAM-1)
ZA896668B (en) * 1988-09-01 1990-06-27 Molecular Therapeutics Inc A human rhinovirus receptor protein that inhibits virus infectivity
US6143298A (en) * 1988-09-01 2000-11-07 Bayer Corporation Soluble truncated forms of ICAM-1
EP0362531B1 (de) 1988-09-01 1999-11-10 Bayer Corporation Menschliches Rhinovirusrezeptorprotein, das die Virusinfektionsanfälligkeit hemmt
US6051231A (en) * 1988-09-01 2000-04-18 Bayer Corporation Antiviral methods and prepations
JPH04505613A (ja) * 1989-03-09 1992-10-01 ダナ・ファーバー・キャンサー・インスティチュート 白血球付着レセプター
EP0462184A4 (en) * 1989-03-09 1992-01-08 Dana Farber Cancer Institute Method of treating viral infections using lfa-1
US6107461A (en) * 1990-07-20 2000-08-22 Bayer Corporation Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use
US5686582A (en) * 1990-07-20 1997-11-11 Bayer Corporation Multimeric forms of human rhinovirus receptor protein
ATE184049T1 (de) * 1990-07-20 1999-09-15 Bayer Ag Multimere formen des menschlichen rhinovirus- rezeptorproteins
US5686581A (en) * 1990-07-20 1997-11-11 Bayer Corporation Multimeric form of human rhinovirus receptor protein
US5120830A (en) * 1990-10-25 1992-06-09 Washington University Inhibitory peptides against α-2, β-1 mediated mg++ dependent adhesion of platelets to collagen
US5629287A (en) * 1991-01-18 1997-05-13 University College London Depot formulations
US5610148A (en) * 1991-01-18 1997-03-11 University College London Macroscopically oriented cell adhesion protein for wound treatment
EP0762886A4 (de) * 1994-04-19 1999-03-31 Univ Kansas Icam-1/lfa-1 kurzkettigen peptide und methoden zu deren verwendung
US6017734A (en) * 1995-07-07 2000-01-25 The Texas A & M University System Unique nucleotide and amino acid sequence and uses thereof
US6075004A (en) 1996-04-26 2000-06-13 The University Of Kansas Peptide compositions which induce immune tolerance and methods of use
AU4825699A (en) * 1998-06-19 2000-01-05 Genzyme Corporation Identification and use of differentially expressed genes and polynucleotide sequences
EP1169048A4 (de) * 1998-07-06 2002-07-17 Glenn D Prestwich Analoge der hyaluronsäure und entsprechende anwendungsverfahren
DK1512695T3 (da) * 2003-09-04 2009-03-16 Biomay Ag Hypoallergeniske polypeptider på fiske-parvalbumin
AU2004287875B2 (en) 2003-11-05 2011-06-02 Bausch + Lomb Ireland Limited Modulators of cellular adhesion
EP2168986A3 (de) 2004-02-19 2010-07-28 Genentech, Inc. Antikörper mit korrigiertem CDR
SI1881823T1 (sl) 2005-05-17 2015-04-30 Sarcode Bioscience Inc. Sestavki in postopki za zdravljenje bolezni oäśesa
CA2702984C (en) 2007-10-19 2017-04-11 Sarcode Corporation Compositions and methods for treatment of diabetic retinopathy
WO2009139817A2 (en) 2008-04-15 2009-11-19 Sarcode Corporation Crystalline pharmaceutical and methods of preparation and use thereof
US8378105B2 (en) 2009-10-21 2013-02-19 Sarcode Bioscience Inc. Crystalline pharmaceutical and methods of preparation and use thereof
EP2877465A4 (de) 2012-07-25 2016-05-11 Sarcode Bioscience Inc Lfa-1-hemmer und polymorph davon

Also Published As

Publication number Publication date
PT91503B (pt) 1996-04-30
EP0362526A2 (de) 1990-04-11
IL91369A0 (en) 1990-04-29
AU634974B2 (en) 1993-03-11
EP0362526A3 (en) 1990-07-18
KR900002796A (ko) 1990-03-23
AU4014589A (en) 1990-03-01
HUT53673A (en) 1990-11-28
DK412589D0 (da) 1989-08-22
ATE123810T1 (de) 1995-06-15
JPH02306999A (ja) 1990-12-20
FI893916A7 (fi) 1990-02-24
NO893366D0 (no) 1989-08-22
PT91503A (pt) 1990-03-08
GR3017303T3 (en) 1995-12-31
ES2075016T3 (es) 1995-10-01
FI893916L (fi) 1990-02-24
EP0362526B1 (de) 1995-06-14
FI893916A0 (fi) 1989-08-21
DE68923048D1 (de) 1995-07-20
DE68923048T2 (de) 1995-11-16
NO893366L (no) 1990-02-26
DK412589A (da) 1990-02-24

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Legal Events

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