IL91648A - Amino acid quinoline and naphthyridine derivatives, their preparation and pharmaceutical compositions containing them - Google Patents
Amino acid quinoline and naphthyridine derivatives, their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL91648A IL91648A IL91648A IL9164889A IL91648A IL 91648 A IL91648 A IL 91648A IL 91648 A IL91648 A IL 91648A IL 9164889 A IL9164889 A IL 9164889A IL 91648 A IL91648 A IL 91648A
- Authority
- IL
- Israel
- Prior art keywords
- alkyl
- hydrogen
- haloalkyl
- preparation
- amino acid
- Prior art date
Links
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 title 2
- 150000001413 amino acids Chemical class 0.000 title 1
- 150000005054 naphthyridines Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- 125000001188 haloalkyl group Chemical group 0.000 abstract 4
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000003381 solubilizing effect Effects 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 125000000335 thiazolyl group Chemical group 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 1
- 229920002554 vinyl polymer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1027—Tetrapeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
- Luminescent Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24799088A | 1988-09-22 | 1988-09-22 | |
| US31326089A | 1989-02-21 | 1989-02-21 | |
| US32840189A | 1989-03-24 | 1989-03-24 | |
| US07/400,111 US5057520A (en) | 1989-03-24 | 1989-09-01 | 7-(peptidylpyrolidinyl)naphthyridine antibacterial compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL91648A0 IL91648A0 (en) | 1990-04-29 |
| IL91648A true IL91648A (en) | 1997-03-18 |
Family
ID=27500274
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL91648A IL91648A (en) | 1988-09-22 | 1989-09-15 | Amino acid quinoline and naphthyridine derivatives, their preparation and pharmaceutical compositions containing them |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0360258B1 (da) |
| JP (1) | JP2938898B2 (da) |
| KR (1) | KR100189474B1 (da) |
| AT (1) | ATE141271T1 (da) |
| AU (1) | AU616053B2 (da) |
| DE (1) | DE68926941T2 (da) |
| DK (1) | DK173511B1 (da) |
| ES (1) | ES2092991T3 (da) |
| GR (1) | GR3021342T3 (da) |
| IE (1) | IE76284B1 (da) |
| IL (1) | IL91648A (da) |
| NZ (1) | NZ230727A (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2676445B1 (fr) * | 1991-05-16 | 1995-02-03 | Esteve Labor Dr | Derives de pyridone amino acide azetidinyl substitues, leur preparation et leur application en tant que medicaments. |
| JP3113440B2 (ja) * | 1992-03-25 | 2000-11-27 | 日本臓器製薬株式会社 | ピリジニウム誘導体 |
| TW252107B (da) * | 1993-08-27 | 1995-07-21 | Hokuriku Pharmacetical Co Ltd | |
| JP3242792B2 (ja) * | 1994-08-05 | 2001-12-25 | 日本臓器製薬株式会社 | ナフチリジニウム誘導体 |
| KR19980701625A (ko) * | 1995-01-24 | 1998-06-25 | 이토 마사노리 | 퀴놀린카르본산유도체 |
| US6613537B2 (en) | 2000-02-29 | 2003-09-02 | Nippon Zoki Pharmaceutical Co., Ltd. | Pyrrolopyridinium derivatives |
| US7067148B2 (en) | 2001-02-15 | 2006-06-27 | King Pharmaceutical Research & Development, Inc. | Stabilized pharmaceutical and thyroid hormone compositions and method of preparation |
| US7101569B2 (en) | 2001-08-14 | 2006-09-05 | Franz G Andrew | Methods of administering levothyroxine pharmaceutical compositions |
| US7589233B2 (en) | 2003-07-29 | 2009-09-15 | Signature R&D Holdings, Llc | L-Threonine derivatives of high therapeutic index |
| US8173840B2 (en) | 2003-07-29 | 2012-05-08 | Signature R&D Holdings, Llc | Compounds with high therapeutic index |
| KR101029764B1 (ko) * | 2010-12-01 | 2011-04-19 | 라현수 | 축산분뇨, 하수슬러지를 토양미생물을 이용하여 발효시키는 장치 및 이를 이용한 발효퇴비 제조방법 |
| CN103396396B (zh) * | 2013-08-12 | 2015-09-09 | 西南大学 | 胺基烷酰克林沙星及其应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5649382A (en) * | 1979-09-28 | 1981-05-02 | Dainippon Pharmaceut Co Ltd | 6-fluoro-7-cyclic amino-1,8-naphthylidine derivative and its salt |
| US4479898A (en) * | 1982-05-18 | 1984-10-30 | Smithkline Beckman Corporation | Oligopeptide prodrugs |
| US4730000A (en) * | 1984-04-09 | 1988-03-08 | Abbott Laboratories | Quinoline antibacterial compounds |
| NZ208470A (en) * | 1983-07-18 | 1988-06-30 | Abbott Lab | 6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid derivatives and antibacterial compositions containing such |
| US4604401A (en) * | 1984-07-20 | 1986-08-05 | Warner-Lambert Company | Antibacterial agents III |
| US4962112A (en) * | 1987-08-04 | 1990-10-09 | Abbott Laboratories | 7-(2-methyl-4-aminopyrrolidinyl)naphthryidine and quinoline compounds |
| US4851418A (en) * | 1987-08-21 | 1989-07-25 | Warner-Lambert Company | Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent |
-
1989
- 1989-09-15 IL IL91648A patent/IL91648A/xx not_active IP Right Cessation
- 1989-09-15 IE IE296489A patent/IE76284B1/en not_active IP Right Cessation
- 1989-09-21 KR KR1019890013566A patent/KR100189474B1/ko not_active Expired - Fee Related
- 1989-09-21 AU AU41724/89A patent/AU616053B2/en not_active Ceased
- 1989-09-21 NZ NZ230727A patent/NZ230727A/xx unknown
- 1989-09-21 DE DE68926941T patent/DE68926941T2/de not_active Expired - Fee Related
- 1989-09-21 EP EP89117428A patent/EP0360258B1/en not_active Expired - Lifetime
- 1989-09-21 AT AT89117428T patent/ATE141271T1/de not_active IP Right Cessation
- 1989-09-21 DK DK198904668A patent/DK173511B1/da not_active IP Right Cessation
- 1989-09-21 ES ES89117428T patent/ES2092991T3/es not_active Expired - Lifetime
- 1989-09-22 JP JP1247841A patent/JP2938898B2/ja not_active Expired - Lifetime
-
1996
- 1996-10-16 GR GR960402715T patent/GR3021342T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE68926941T2 (de) | 1997-03-20 |
| JP2938898B2 (ja) | 1999-08-25 |
| EP0360258A3 (en) | 1991-06-05 |
| EP0360258B1 (en) | 1996-08-14 |
| DE68926941D1 (de) | 1996-09-19 |
| AU616053B2 (en) | 1991-10-17 |
| GR3021342T3 (en) | 1997-01-31 |
| KR900004732A (ko) | 1990-04-12 |
| IE76284B1 (en) | 1997-10-08 |
| JPH02142786A (ja) | 1990-05-31 |
| EP0360258A2 (en) | 1990-03-28 |
| DK466889A (da) | 1990-03-23 |
| DK466889D0 (da) | 1989-09-21 |
| ATE141271T1 (de) | 1996-08-15 |
| IE892964L (en) | 1990-03-22 |
| IL91648A0 (en) | 1990-04-29 |
| AU4172489A (en) | 1990-04-26 |
| ES2092991T3 (es) | 1996-12-16 |
| NZ230727A (en) | 1991-08-27 |
| DK173511B1 (da) | 2001-01-15 |
| KR100189474B1 (ko) | 1999-06-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE94065T1 (de) | Diazepine enthaltende pharmazeutische zusammensetzungen mit plaettchen aktivierender faktor (paf)-antagonistischer wirkung. | |
| AR015769A1 (es) | Derivados de imidazo piridina que inhiben la secrecion de acido gastrico, procedimiento para la preparacion de dichos derivados, composicion farmaceutica, uso de dichos derivados para la preparacion de medicamentos, y compuestos intermediarios. | |
| HUP9802937A2 (hu) | Benzo[g]kinolin-származékok, e vegyületeket tartalmazó gyógyászati készítmények, eljárás előállításukra és alkalmazásuk | |
| ES8404990A1 (es) | Un procedimiento para la preparacion de derivados de prolina. | |
| IL91648A (en) | Amino acid quinoline and naphthyridine derivatives, their preparation and pharmaceutical compositions containing them | |
| HU904785D0 (en) | Process for the production of medicaments | |
| DE2960820D1 (en) | Carbostyrile derivatives, processes for their preparation and pharmaceutical compositions containing them | |
| CA2136553A1 (en) | 7-(2-aminoethyl)-Benzothiazolones | |
| BG94282A (bg) | 2,9-дизаместени-4н-пиридо/1,2,-а/пиримидин-4-они | |
| MY101801A (en) | Novel phenoxyacetic acid derivatives, process for preparing the same and pharmaceutical composition having the same as an active ingredient. | |
| TW249804B (da) | ||
| DE69006872D1 (de) | 1H,3H,7-Pyrrolo [1,2-c]thiazolcarbonsäureamid-Derivate, ihre Herstellung und diese enthaltende pharmazeutische Zubereitungen. | |
| ES479820A1 (es) | Procedimiento para la preparacion de isoquinoleinas. | |
| IL76175A (en) | N-substituted tricyclic oxindole carboxamides and pharmaceutical compositions containing them | |
| NO160783C (no) | Analogifremgangsmaate til fremstilling av terapeutisk aktive substituerte beta-karbolinderivater. | |
| ES8506634A1 (es) | Un procedimiento para la preparacion de derivados de isoquinuclidina. | |
| FR2663029B1 (fr) | Derives de benzothiazole, leur preparation et les medicaments les contenant. | |
| MY103515A (en) | Ergolinyl heterocycles | |
| ATE18211T1 (de) | Chinolinessigsaeuren und diese enthaltende pharmazeutische zubereitungen. | |
| EP0487996A3 (en) | Cephalosporins substituted in position 3, process for their preparation and their use as medicine | |
| ZA899321B (en) | Indole derivatives,process for preparing them and pharmaceutical compositions containing them | |
| TW337983B (en) | 1, 3-oxazn-4-one derivatives, their preparation and uses | |
| MY102282A (en) | Isoxazole derivatives with antiviral activities and pharmaceutical products containing these. | |
| IE40722L (en) | Indolopiperidino -alkylphenothiazines | |
| ATE66231T1 (de) | Dioxolobenzisoxazolderivate und verfahren zu ihrer herstellung. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| RH1 | Patent not in force |