IL92083A0 - Naphthalenepropionic acid salts - Google Patents
Naphthalenepropionic acid saltsInfo
- Publication number
- IL92083A0 IL92083A0 IL92083A IL9208389A IL92083A0 IL 92083 A0 IL92083 A0 IL 92083A0 IL 92083 A IL92083 A IL 92083A IL 9208389 A IL9208389 A IL 9208389A IL 92083 A0 IL92083 A0 IL 92083A0
- Authority
- IL
- Israel
- Prior art keywords
- carbon atoms
- hydroxyalkyl
- salts
- acid salts
- amine
- Prior art date
Links
- PRLKVVMRQFFIOQ-UHFFFAOYSA-N 3-naphthalen-1-ylpropanoic acid Chemical class C1=CC=C2C(CCC(=O)O)=CC=CC2=C1 PRLKVVMRQFFIOQ-UHFFFAOYSA-N 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- -1 amine salts Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- QWFAMXAVDCZEBZ-UHFFFAOYSA-N 2-[6-(quinolin-2-ylmethoxy)naphthalen-2-yl]propanoic acid Chemical compound C1=CC=CC2=NC(COC3=CC4=CC=C(C=C4C=C3)C(C(O)=O)C)=CC=C21 QWFAMXAVDCZEBZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical class OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/351,119 US4960892A (en) | 1988-06-10 | 1989-05-12 | Naphthalenepropionic acid derivatives as anti-inflammatory/anti-allergic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL92083A0 true IL92083A0 (en) | 1990-07-12 |
Family
ID=23379653
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL92083A IL92083A0 (en) | 1989-05-12 | 1989-10-23 | Naphthalenepropionic acid salts |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4960892A (de) |
| EP (1) | EP0396839B1 (de) |
| JP (1) | JPH02311463A (de) |
| KR (1) | KR900018033A (de) |
| AT (1) | ATE104281T1 (de) |
| AU (1) | AU629868B2 (de) |
| CA (1) | CA1331001C (de) |
| DE (1) | DE68914646T2 (de) |
| DK (1) | DK169545B1 (de) |
| ES (1) | ES2063143T3 (de) |
| GB (1) | GB2231570B (de) |
| IE (1) | IE61967B1 (de) |
| IL (1) | IL92083A0 (de) |
| NZ (1) | NZ231255A (de) |
| ZA (1) | ZA898291B (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5208344A (en) * | 1987-07-31 | 1993-05-04 | American Home Products Corporation | Naphthalenepropionic acid derivatives as anti-inflammatory/antiallergic agents |
| US5084575A (en) * | 1987-07-31 | 1992-01-28 | American Home Products Corporation | Quinoline substituted naphthalenepropionic acid derivatives as anti-inflammatory/antiallergic agents |
| JPH0317061A (ja) * | 1989-06-13 | 1991-01-25 | Kyorin Pharmaceut Co Ltd | 新規環状アントラニル酸酢酸誘導体 |
| EP0540165A1 (de) * | 1991-10-03 | 1993-05-05 | Zeneca Limited | Alkonsäurederivate |
| ES2058024B1 (es) * | 1992-11-10 | 1995-05-01 | Menarini Lab | Nuevo derivado arilpropionico, procedimiento de fabricacion del mismo y su utilizacion como analgesico. |
| ES2124196B1 (es) * | 1997-06-04 | 1999-12-01 | Menarini Lab | Procedimiento para la fabricacion de una forma farmaceutica semisolida conteniendo dexketoprofeno trometamol y su utilizacion en el tratamiento topico de la inflamacion. |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3904682A (en) * | 1967-01-13 | 1975-09-09 | Syntex Corp | 2-(6{40 -Methoxy-2{40 -naphthyl)acetic acid |
| DE2134672A1 (de) * | 1971-07-08 | 1973-01-25 | Josef Dipl Chem Dr Rer N Klosa | Wasserloesliches acetylsalicylsaeuresalz, dessen herstellung, zubereitung und anwendung |
| US4097674A (en) * | 1975-03-17 | 1978-06-27 | Syntex Corporation | 2-Naphthylacetic acid derivatives |
| HU185926B (en) * | 1979-09-27 | 1985-04-28 | Agostne Kahan | Process for preparing water soluble derivatives of non-steroid antiinflammatory compositions and pharmaceutical compositins containing such derivatives |
| AT370721B (de) * | 1981-02-24 | 1983-04-25 | Ciba Geigy Ag | Verfahren zur herstellung von neuen salzen der 2- (2,6-dichloranilino)-phenylessigsaeure, der |
| US4794188A (en) * | 1982-12-01 | 1988-12-27 | Usv Pharmaceutical Corporation | Certain unsymmetrical quinolinyl ethers having anti-inflammatory and anti-allergic activity |
| US4661596A (en) * | 1985-02-21 | 1987-04-28 | American Home Products Corporation | Quinolinyl (or pyridinyl) methoxy substituted naphthalene compounds as antiallergic agents |
| US4631287A (en) * | 1985-04-16 | 1986-12-23 | Usv Pharmaceutical Corp. | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments |
| US4754043A (en) * | 1985-10-03 | 1988-06-28 | American Home Products Corporation | Oxazole and thiazole naphthalenes as antiallergic agents |
| US4732978A (en) * | 1985-10-03 | 1988-03-22 | American Home Products Corporation | Novel substituted naphthyloxymethyl quinoline derivatives as anti-inflammatory and antiallergy agents |
| US4772703A (en) * | 1986-01-27 | 1988-09-20 | American Home Products Corporation | 2-(phenoxymethyl)-quinazolines as antiallergic and antiinflammatory agents |
| AU611699B2 (en) * | 1987-07-31 | 1991-06-20 | American Home Products Corporation | Naphthalene propionic acid derivatives |
| EP0988144A1 (de) * | 1997-06-12 | 2000-03-29 | Northrop Grumman Corporation | Wärmebeständige verbundstruktur |
-
1989
- 1989-05-12 US US07/351,119 patent/US4960892A/en not_active Expired - Lifetime
- 1989-09-26 CA CA000613074A patent/CA1331001C/en not_active Expired - Fee Related
- 1989-10-23 IL IL92083A patent/IL92083A0/xx not_active IP Right Cessation
- 1989-10-26 JP JP1279615A patent/JPH02311463A/ja active Pending
- 1989-10-31 ES ES89311231T patent/ES2063143T3/es not_active Expired - Lifetime
- 1989-10-31 AT AT89311231T patent/ATE104281T1/de active
- 1989-10-31 EP EP89311231A patent/EP0396839B1/de not_active Expired - Lifetime
- 1989-10-31 DE DE68914646T patent/DE68914646T2/de not_active Expired - Fee Related
- 1989-10-31 GB GB8924501A patent/GB2231570B/en not_active Expired - Fee Related
- 1989-10-31 ZA ZA898291A patent/ZA898291B/xx unknown
- 1989-11-01 IE IE351989A patent/IE61967B1/en not_active IP Right Cessation
- 1989-11-03 AU AU44361/89A patent/AU629868B2/en not_active Ceased
- 1989-11-03 NZ NZ231255A patent/NZ231255A/xx unknown
- 1989-11-08 KR KR1019890016130A patent/KR900018033A/ko not_active Withdrawn
-
1990
- 1990-05-10 DK DK117590A patent/DK169545B1/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU629868B2 (en) | 1992-10-15 |
| GB2231570A (en) | 1990-11-21 |
| ATE104281T1 (de) | 1994-04-15 |
| EP0396839A3 (de) | 1991-06-05 |
| IE61967B1 (en) | 1994-11-30 |
| CA1331001C (en) | 1994-07-26 |
| EP0396839B1 (de) | 1994-04-13 |
| GB2231570B (en) | 1992-05-20 |
| KR900018033A (ko) | 1990-12-20 |
| DK169545B1 (da) | 1994-11-28 |
| EP0396839A2 (de) | 1990-11-14 |
| JPH02311463A (ja) | 1990-12-27 |
| ES2063143T3 (es) | 1995-01-01 |
| DK117590A (da) | 1990-11-13 |
| US4960892A (en) | 1990-10-02 |
| DE68914646D1 (de) | 1994-05-19 |
| NZ231255A (en) | 1991-02-26 |
| DE68914646T2 (de) | 1994-07-21 |
| IE893519L (en) | 1990-11-12 |
| DK117590D0 (da) | 1990-05-10 |
| ZA898291B (en) | 1991-06-26 |
| AU4436189A (en) | 1990-11-15 |
| GB8924501D0 (en) | 1989-12-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |