IL92826A - Chemical process for preparing antibiotic L17392 (deglucoteicoplanin) and its salts - Google Patents

Chemical process for preparing antibiotic L17392 (deglucoteicoplanin) and its salts

Info

Publication number: IL92826A
Authority: IL; Israel
Prior art keywords: deglucoteicoplanin; salts; chemical process; preparing antibiotic; teicoplanin
Prior art date: 1988-12-27

Application number

IL9282689A

Other languages

English (en)

Other versions

IL92826A0 (en

Inventor

Giambattista Panzone

Anacleto Gianantonio

Original Assignee

Lepetit Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-12-27

Filing date

1989-12-20

Publication date

1994-06-24

1989-12-20 Application filed by Lepetit Spa filed Critical Lepetit Spa

1990-09-17 Publication of IL92826A0 publication Critical patent/IL92826A0/xx

1994-06-24 Publication of IL92826A publication Critical patent/IL92826A/xx

Links

238000001311 chemical methods and process Methods 0.000 title abstract 2
150000003839 salts Chemical class 0.000 title abstract 2
DKVBOUDTNWVDEP-NJCHZNEYSA-N teicoplanin aglycone Chemical compound N([C@H](C(N[C@@H](C1=CC(O)=CC(O)=C1C=1C(O)=CC=C2C=1)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)OC=1C=C3C=C(C=1O)OC1=CC=C(C=C1Cl)C[C@H](C(=O)N1)NC([C@H](N)C=4C=C(O5)C(O)=CC=4)=O)C(=O)[C@@H]2NC(=O)[C@@H]3NC(=O)[C@@H]1C1=CC5=CC(O)=C1 DKVBOUDTNWVDEP-NJCHZNEYSA-N 0.000 title abstract 2
DKVBOUDTNWVDEP-ZCVCDMNQSA-N teicoplanin aglycone Chemical compound N([C@H](C(N[C@@H](C1=CC(O)=CC(O)=C1C=1C(O)=CC=C2C=1)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)OC=1C=C3C=C(C=1O)OC1=CC=C(C=C1Cl)C[C@H](C(=O)N1)NC([C@H](N)C=4C=C(O5)C(O)=CC=4)=O)C(=O)C2NC(=O)[C@@H]3NC(=O)[C@@H]1C1=CC5=CC(O)=C1 DKVBOUDTNWVDEP-ZCVCDMNQSA-N 0.000 title abstract 2
108010053950 Teicoplanin Proteins 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
238000005903 acid hydrolysis reaction Methods 0.000 abstract 1
150000007513 acids Chemical class 0.000 abstract 1
239000000010 aprotic solvent Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
238000000746 purification Methods 0.000 abstract 1
229960001608 teicoplanin Drugs 0.000 abstract 1
-1 teicoplanin compound Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
- C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Life Sciences & Earth Sciences (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Compounds Of Unknown Constitution (AREA)
Materials For Medical Uses (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IL9282689A 1988-12-27 1989-12-20 Chemical process for preparing antibiotic L17392 (deglucoteicoplanin) and its salts IL92826A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP88121707		1988-12-27

Publications (2)

Publication Number	Publication Date
IL92826A0 IL92826A0 (en)	1990-09-17
IL92826A true IL92826A (en)	1994-06-24

Family

ID=8199721

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL9282689A IL92826A (en)	1988-12-27	1989-12-20	Chemical process for preparing antibiotic L17392 (deglucoteicoplanin) and its salts

Country Status (12)

Country	Link
US (1)	US5594102A (ja)
EP (1)	EP0376042B1 (ja)
JP (1)	JPH02221297A (ja)
KR (1)	KR900009652A (ja)
AT (1)	ATE135369T1 (ja)
CA (1)	CA2006381A1 (ja)
DE (1)	DE68925951T2 (ja)
DK (1)	DK640589A (ja)
ES (1)	ES2084595T3 (ja)
HU (1)	HU209314B (ja)
IL (1)	IL92826A (ja)
ZA (1)	ZA899773B (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8621912D0 (en) *	1986-09-11	1986-10-15	Lepetit Spa	Increasing ratio of components of anti-biotic complex
KR20000010589A (ko)	1996-04-23	2000-02-15	클라우디오 쿼르타	항생제a40926의아미드유도체의개선된화학적제조방법
CN101273272B (zh) *	2005-09-29	2012-11-07	霍夫曼-拉罗奇有限公司	维生素d化合物的释放试剂
EP2572204B1 (en)	2010-05-20	2017-12-27	Roche Diagnostics GmbH	Release reagent for vitamin d compounds
EP3467510B1 (en)	2011-11-18	2022-10-26	F. Hoffmann-La Roche AG	Release reagent for vitamin d compounds

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1496386A (en) *	1975-03-05	1977-12-30	Lepetit Spa	Antibiotics
US4604239A (en) *	1982-03-24	1986-08-05	Eli Lilly And Company	Antibiotics
GB8307847D0 (en) *	1983-03-22	1983-04-27	Lepetit Spa	Antibiotics l 17054 and l 17046
US4521335A (en) *	1983-07-13	1985-06-04	Smithkline Beckman Corporation	Aglycone and pseudo-aglycones of the AAD 216 antibiotics
AU579120B2 (en) *	1983-12-16	1988-11-17	Gruppo Lepetit S.P.A.	Chemical process for preparing antibiotic L 17392 (deglucoteicoplanin) and its salts
IT1173329B (it) *	1984-02-21	1987-06-24	Lepetit Spa	Procedimento per la trasformazione quantitativa di teicoplanina a2 fattore 1 in teicoplanina a2 fattore 3
GB8415093D0 (en) *	1984-06-13	1984-07-18	Lepetit Spa	Antibiotic l 17392
GB8420405D0 (en) *	1984-08-10	1984-09-12	Lepetit Spa	Preparing antibiotic l 17046
GB8531846D0 (en) *	1985-12-30	1986-02-05	Lepetit Spa	Antibiotic a 40926 mannosyl aglycon
GB8608809D0 (en) *	1986-04-11	1986-05-14	Lepetit Spa	Antibiotic
US4742045A (en) *	1986-07-30	1988-05-03	Smithkline Beckman Corporation	Glycopeptide antibiotics
EP0255299A3 (en) *	1986-07-30	1988-07-20	Smithkline Beecham Corporation	Glycopeptide antibiotics
GB8715735D0 (en) *	1987-07-03	1987-08-12	Lepetit Spa	De-mannosyl teicoplanin derivatives
GB8720980D0 (en) *	1987-09-07	1987-10-14	Lepetit Spa	Derivatives

1989
- 1989-12-12 EP EP89122875A patent/EP0376042B1/en not_active Expired - Lifetime
- 1989-12-12 AT AT89122875T patent/ATE135369T1/de not_active IP Right Cessation
- 1989-12-12 ES ES89122875T patent/ES2084595T3/es not_active Expired - Lifetime
- 1989-12-12 DE DE68925951T patent/DE68925951T2/de not_active Expired - Fee Related
- 1989-12-18 DK DK640589A patent/DK640589A/da not_active Application Discontinuation
- 1989-12-20 ZA ZA899773A patent/ZA899773B/xx unknown
- 1989-12-20 IL IL9282689A patent/IL92826A/xx unknown
- 1989-12-21 CA CA002006381A patent/CA2006381A1/en not_active Abandoned
- 1989-12-22 HU HU896773A patent/HU209314B/hu not_active IP Right Cessation
- 1989-12-26 KR KR1019890019475A patent/KR900009652A/ko not_active Withdrawn
- 1989-12-27 JP JP1336812A patent/JPH02221297A/ja active Pending
1995
- 1995-05-30 US US08/453,114 patent/US5594102A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US5594102A (en)	1997-01-14
ES2084595T3 (es)	1996-05-16
HU209314B (en)	1994-04-28
KR900009652A (ko)	1990-07-05
EP0376042A1 (en)	1990-07-04
DE68925951T2 (de)	1996-07-25
CA2006381A1 (en)	1990-06-27
HUT53377A (en)	1990-10-28
JPH02221297A (ja)	1990-09-04
EP0376042B1 (en)	1996-03-13
HU896773D0 (en)	1990-03-28
DE68925951D1 (de)	1996-04-18
ZA899773B (en)	1991-02-27
ATE135369T1 (de)	1996-03-15
DK640589A (da)	1990-06-28
IL92826A0 (en)	1990-09-17
DK640589D0 (da)	1989-12-18

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