IL93051A0 - ((5-oxo-2-pyrrolidinyl)methyl)cyclohexaneacetamides,their preparation and pharmaceutical compositions containing them - Google Patents

((5-oxo-2-pyrrolidinyl)methyl)cyclohexaneacetamides,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL93051A0
IL93051A0 IL93051A IL9305190A IL93051A0 IL 93051 A0 IL93051 A0 IL 93051A0 IL 93051 A IL93051 A IL 93051A IL 9305190 A IL9305190 A IL 9305190A IL 93051 A0 IL93051 A0 IL 93051A0
Authority
IL
Israel
Prior art keywords
lower alkyl
aryl
hydrogen
cyclohexaneacetamides
pyrrolidinyl
Prior art date
Application number
IL93051A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL93051A0 publication Critical patent/IL93051A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/08—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing alicyclic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Packging For Living Organisms, Food Or Medicinal Products That Are Sensitive To Environmental Conditiond (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL93051A 1989-01-17 1990-01-15 ((5-oxo-2-pyrrolidinyl)methyl)cyclohexaneacetamides,their preparation and pharmaceutical compositions containing them IL93051A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29772689A 1989-01-17 1989-01-17
US37764389A 1989-07-10 1989-07-10

Publications (1)

Publication Number Publication Date
IL93051A0 true IL93051A0 (en) 1990-11-05

Family

ID=26970288

Family Applications (1)

Application Number Title Priority Date Filing Date
IL93051A IL93051A0 (en) 1989-01-17 1990-01-15 ((5-oxo-2-pyrrolidinyl)methyl)cyclohexaneacetamides,their preparation and pharmaceutical compositions containing them

Country Status (16)

Country Link
EP (1) EP0381959B1 (fr)
JP (1) JPH02229154A (fr)
KR (1) KR900011759A (fr)
AT (1) ATE122037T1 (fr)
AU (1) AU625157B2 (fr)
CA (1) CA2007732A1 (fr)
DE (1) DE69019007T2 (fr)
DK (1) DK0381959T3 (fr)
ES (1) ES2071685T3 (fr)
FI (1) FI900231A7 (fr)
HU (1) HUT53607A (fr)
IL (1) IL93051A0 (fr)
MC (1) MC2081A1 (fr)
NO (1) NO174386C (fr)
NZ (1) NZ232112A (fr)
PT (1) PT92874A (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4404848A1 (de) * 1994-02-16 1995-08-17 Hoechst Ag Substituierte Cyclohexanolester, ihre Verwendung zur Behandlung von Krankheiten und pharmazeutische Präparate
KR100395779B1 (ko) * 2001-05-25 2003-08-21 한국화학연구원 임의적으로 베타-위치가 치환된 알파-아릴알킬기의 제거를통해 3급 아미드 화합물로부터 2급 아미드 화합물을제조하는 방법
ES2865504T3 (es) 2008-10-16 2021-10-15 Univ Johns Hopkins Procedimientos y composiciones para la mejora de la función cognitiva
US20140206667A1 (en) 2012-11-14 2014-07-24 Michela Gallagher Methods and compositions for treating schizophrenia
JP6433482B2 (ja) 2013-03-15 2018-12-05 エージンバイオ， インコーポレイテッド 認知機能を改善するための方法および組成物
WO2014144663A1 (fr) 2013-03-15 2014-09-18 The Johns Hopkins University Procédés et compositions pour améliorer la fonction cognitive
WO2016191288A1 (fr) 2015-05-22 2016-12-01 Agenebio, Inc. Compositions pharmaceutiques de lévétiracétam à libération prolongée

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1045043B (it) * 1975-08-13 1980-04-21 Isf Spa Derivati pirrolidinici
DE3336024A1 (de) * 1983-10-04 1985-04-18 Boehringer Ingelheim KG, 6507 Ingelheim 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel
US4668687A (en) * 1984-07-23 1987-05-26 Bristol-Myers Company Psychogeriatric 1-(2-pyrimidinyl)piperazinyl derivatives of 1-pyrrolidin-2-ones
IT1190378B (it) * 1985-06-21 1988-02-16 Isf Spa Derivati pirrolidonici
IT1224168B (it) * 1986-08-01 1990-09-26 Finanziaria R F Spa Ora Finanz Derivati del pirrolidin-2-one ad attivita' nootropa

Also Published As

Publication number Publication date
NO900234L (no) 1990-07-18
NO174386B (no) 1994-01-17
AU625157B2 (en) 1992-07-02
AU4798890A (en) 1990-07-26
EP0381959B1 (fr) 1995-05-03
FI900231A7 (fi) 1990-07-18
NO174386C (no) 1994-04-27
EP0381959A1 (fr) 1990-08-16
DE69019007T2 (de) 1995-09-14
JPH02229154A (ja) 1990-09-11
ES2071685T3 (es) 1995-07-01
MC2081A1 (fr) 1991-01-07
HUT53607A (en) 1990-11-28
DK0381959T3 (da) 1995-09-04
ATE122037T1 (de) 1995-05-15
DE69019007D1 (de) 1995-06-08
CA2007732A1 (fr) 1990-07-17
PT92874A (pt) 1990-07-31
HU900127D0 (en) 1990-03-28
NO900234D0 (no) 1990-01-16
NZ232112A (en) 1992-07-28
KR900011759A (ko) 1990-08-02
FI900231A0 (fi) 1990-01-16

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Legal Events

Date Code Title Description
RH Patent void