IL93177A0 - Heterocyclic nitromethane derivatives - Google Patents
Heterocyclic nitromethane derivativesInfo
- Publication number
- IL93177A0 IL93177A0 IL93177A IL9317790A IL93177A0 IL 93177 A0 IL93177 A0 IL 93177A0 IL 93177 A IL93177 A IL 93177A IL 9317790 A IL9317790 A IL 9317790A IL 93177 A0 IL93177 A0 IL 93177A0
- Authority
- IL
- Israel
- Prior art keywords
- ring
- phenyl
- alkyl
- atoms
- optionally substituted
- Prior art date
Links
- -1 Heterocyclic nitromethane derivatives Chemical class 0.000 title abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 6
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 2
- 125000004429 atom Chemical group 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- BONYJLSUCJTVGL-UHFFFAOYSA-N 4-(nitromethylsulfonyl)morpholine Chemical compound [O-][N+](=O)CS(=O)(=O)N1CCOCC1 BONYJLSUCJTVGL-UHFFFAOYSA-N 0.000 abstract 1
- 208000002249 Diabetes Complications Diseases 0.000 abstract 1
- 206010012655 Diabetic complications Diseases 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
- 125000006413 ring segment Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000004044 trifluoroacetyl group Chemical group FC(C(=O)*)(F)F 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/26—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
- C07D207/48—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/96—Sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/58—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Quinoline Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB898902405A GB8902405D0 (en) | 1989-02-03 | 1989-02-03 | Heterocyclic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL93177A0 true IL93177A0 (en) | 1990-11-05 |
Family
ID=10651067
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL93177A IL93177A0 (en) | 1989-02-03 | 1990-01-25 | Heterocyclic nitromethane derivatives |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5096918A (de) |
| EP (1) | EP0408714B1 (de) |
| JP (1) | JPH03503900A (de) |
| AT (1) | ATE100797T1 (de) |
| AU (1) | AU631400B2 (de) |
| CA (1) | CA2025664A1 (de) |
| DE (1) | DE69006274D1 (de) |
| GB (1) | GB8902405D0 (de) |
| GR (1) | GR1000444B (de) |
| IE (1) | IE900255L (de) |
| IL (1) | IL93177A0 (de) |
| NZ (1) | NZ232348A (de) |
| PT (1) | PT93051A (de) |
| WO (1) | WO1990008762A1 (de) |
| ZA (1) | ZA90637B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5250570A (en) * | 1990-08-02 | 1993-10-05 | Imperial Chemical Industries Plc | Amidobenzene derivatives, compositions and use |
| JPH05255089A (ja) * | 1991-12-18 | 1993-10-05 | Sanwa Kagaku Kenkyusho Co Ltd | 抗ウイルス剤 |
| NZ254550A (en) * | 1992-09-28 | 1997-08-22 | Pfizer | Use of nitrogen-substituted pyrimidines to prepare medicaments useful for treatment or prevention of diabetic complications |
| US5516534A (en) * | 1993-11-26 | 1996-05-14 | Rensselaer Polytechnic Institute | Composition and method for reducing structural defects |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1229653A (de) * | 1968-03-14 | 1971-04-28 | ||
| US4053633A (en) * | 1976-06-24 | 1977-10-11 | The Dow Chemical Company | Aryl dibromonitromethyl sulfones |
| GB8718619D0 (en) * | 1987-08-06 | 1987-09-09 | Ici Plc | Pharmaceutical compositions |
-
1989
- 1989-02-03 GB GB898902405A patent/GB8902405D0/en active Pending
-
1990
- 1990-01-23 IE IE900255A patent/IE900255L/xx unknown
- 1990-01-25 IL IL93177A patent/IL93177A0/xx unknown
- 1990-01-29 ZA ZA90637A patent/ZA90637B/xx unknown
- 1990-02-01 CA CA002025664A patent/CA2025664A1/en not_active Abandoned
- 1990-02-01 AU AU50208/90A patent/AU631400B2/en not_active Ceased
- 1990-02-01 WO PCT/GB1990/000163 patent/WO1990008762A1/en not_active Ceased
- 1990-02-01 DE DE90902343T patent/DE69006274D1/de not_active Expired - Lifetime
- 1990-02-01 EP EP90902343A patent/EP0408714B1/de not_active Expired - Lifetime
- 1990-02-01 AT AT90902343T patent/ATE100797T1/de active
- 1990-02-01 JP JP2502693A patent/JPH03503900A/ja active Pending
- 1990-02-02 PT PT93051A patent/PT93051A/pt not_active Application Discontinuation
- 1990-02-02 NZ NZ232348A patent/NZ232348A/en unknown
- 1990-02-05 US US07/474,935 patent/US5096918A/en not_active Expired - Fee Related
- 1990-02-05 GR GR900100067A patent/GR1000444B/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0408714B1 (de) | 1994-01-26 |
| ATE100797T1 (de) | 1994-02-15 |
| GR900100067A (en) | 1991-06-28 |
| AU631400B2 (en) | 1992-11-26 |
| CA2025664A1 (en) | 1990-08-04 |
| WO1990008762A1 (en) | 1990-08-09 |
| ZA90637B (en) | 1990-10-31 |
| GR1000444B (el) | 1992-07-30 |
| PT93051A (pt) | 1990-08-31 |
| DE69006274D1 (de) | 1994-03-10 |
| AU5020890A (en) | 1990-08-24 |
| NZ232348A (en) | 1992-04-28 |
| EP0408714A1 (de) | 1991-01-23 |
| GB8902405D0 (en) | 1989-03-22 |
| JPH03503900A (ja) | 1991-08-29 |
| US5096918A (en) | 1992-03-17 |
| IE900255L (en) | 1990-08-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU557691B2 (en) | 2-penem antibiotics and their oxa-aza-, and carba analogues | |
| ZA90637B (en) | Heterocyclic nitromethane derivatives | |
| AU532411B2 (en) | Phenyl piperazine derivatives | |
| AU576887B2 (en) | 1,6-naphthyridine derivatives | |
| SE7605190L (sv) | Nya tiazoliner | |
| IL61687A (en) | (benzothiazole-2-yl-thio)-phenylpropionic acid derivatives,pharmaceutical formulations containing them and a process for their preparation | |
| NZ216125A (en) | Isoxazoles and pharmaceutical compositions | |
| DE3167347D1 (en) | New benzothiazine derivatives, processes for preparation thereof and use thereof | |
| AU586485B2 (en) | New thieno-1,2-thiazole derivatives, a process for their prepaeration and pharmaceutical products containing these compounds | |
| IL93178A0 (en) | Benzheterocyclyl sulphones | |
| ZA811149B (en) | Cyclohepitindolol derivatives and their salts with the acids, their preparation, their use as medicaments and the compositions containing them | |
| AU601942B2 (en) | New esters derived from 4-hydroxy-3-quinoline carboxylic acid substituted by an alpha-hydroxyl chain at position 2, their preparation, their use as a medicament and the compositions containing them |